Transient Elastography for Significant Liver Fibrosis and Cirrhosis in Chronic Hepatitis B: A Meta-Analysis by Xiaolong Qi, Min An, Tongwei Wu, Deke Jiang, Mengyun Peng, Weidong Wang, Jing Wang, Chunqing Zhang, on behalf of the CHESS Study Group

“…The sensitivity, specificity, and diagnostic odds ratio of TE for significant fibrosis were 0.78 (95% CI: 0.73–0.81, p<0.01; I2=85.59%), 0.81 (95% CI: 0.77–0.84, p<0.01; I2=88.20%), and 14.44 (95% CI: 10.80–19.31, p<0.01; I2=100%) and for cirrhosis were 0.84 (95% CI: 0.80–0.88, p<0.01; I2=76.67%), 0.87 (95% CI: 0.84–0.90, p<0.01; I2=90.89%), and 36.63 (95% CI: 25.38–52.87, p<0.01; I2=100%), respectively. …”
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Scrub typhus in pregnancy: A 10-year multicenter study in resource-limited settings in China. by Peilin Zhao, Tieyong Dong, Hongbin Lu, Rui Zhu, Shanshan Zhao, Wuqian Tao, Li Li, Chunmei Liu, Shuwei Pu, Ling Mo, Huanhuan Wang

“…The use of macrolides reduced the risk of a poor fetal outcome, while lower gestational age (GA) at the time of infection, pneumonia, leucopoenia, thrombocytopenia, and use of chloramphenicol were associated with a poor fetal outcome in univariate logistic-regression analysis, but only lower GA at the time of infection and pneumonia were independent risk factors for a poor fetal outcome on multivariate logistic-regression analysis with an odds ratio of 6.6 (95% CI 2.4-17.8, p < 0.001) and 3.1 (95% CI 1.3-7.6, p = 0.011).…”
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Frequency of viral etiology in community-acquired pneumonia by Zain Ahmad Khan, Akbar Shoukat Ali, Imran Ahmed, Joveria Farooqi, Muhammad Irfan

“…Confusion-Urea-Respiratory Rate-Blood Pressure-Age of 65 scores of 3-5 [odds ratio (OR) 4.234; 95% confidence interval 1.156-15.501], leukocytosis (OR 0.137; 0.030-0.636), high C-reactive protein (>10mg/L) (OR 1.008; 1.001-1.014), high serum procalcitonin level (≥0.5 ng/mL) (OR 10.731; 3.018-38.153), and mechanical ventilation required (OR 47.104; 13.644-162.625) were associated with mortality. …”
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Association of triglyceride glucose-related obesity indices with sarcopenia among U.S. adults: a cross-sectional study from the National Health and Nutrition Examination Survey by Runtao Zhao, Xinqiang Ji, Fan Wang

“…Additionally, regression analyses demonstrated TyG-WHtR as a significant predictor of sarcopenia with the highest odds ratio, reaching 12.50 (95% CI: 6.13–25.70, P < 0.001) for the upper fourth quartile (Q4) compared to the first quartile, followed by followed by TyG-BMI (Q4: 3.34; 95% CI: 1.92–5.80, P < 0.001) and TyG-WC (Q4: 1.95; 95% CI: 1.04–3.68, P < 0.001). …”
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Clinical Value of Renal Function Markers Combined with Blood Lipid Levels during Late Pregnancy to Predict Preeclampsia: A Retrospective Case-Control Study by Jindi Zhang, Pei Wang, Jie Liu

“…Multivariable analysis showed that the serum TG [adjusted odds ratio (AOR) = 1.827 (95% confidence interval (95% CI) = 1.277–2.615)], Cr [AOR = 1.066 (95% CI = 1.028–1.106)] and UA [AOR = 1.016 (95% CI = 1.011–1.022)] were risk factors for PE (p < 0.001). …”
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Insights Into Causal Effects of Genetically Proxied Lipids and Lipid‐Modifying Drug Targets on Cardiometabolic Diseases by Liwan Fu, Qin Liu, Hong Cheng, Xiaoyuan Zhao, Jingfan Xiong, Jie Mi

“…Notably, genetic enhancement of LPL (lipoprotein lipase) was linked to reduced risks of myocardial infarction (odds ratio [OR]1, 0.65 [95% CI, 0.57–0.75], P1=2.60×10−9; OR2, 0.59 [95% CI, 0.49–0.72], P2=1.52×10−7), ischemic heart disease (OR1, 0.968 [95% CI, 0.962–0.975], P1=5.50×10−23; OR2, 0.64 [95% CI, 0.55–0.73], P2=1.72×10−10), and coronary heart disease (OR1, 0.980 [95% CI, 0.975–0.985], P1=3.63×10−14; OR2, 0.64 [95% CI, 0.54–0.75], P2=6.62×10−8) across 2 data sets. …”
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The mediating role of body surface area-adjusted basal metabolic rate: effects of low muscle mass and central obesity on cognitive impairment in Chinese patients with type 2 diabet... by Ya-Jie Zhai, Ya-Jie Zhai, Fang Li, Chen-Ying Lin, Chen-Ying Lin, Fan Wu, Hui-Na Qiu, Jing-Bo Li, Jing-Na Lin

“…Logistic regression showed that participants in the fourth quartile of BMR, BMR/Height2, and BMR/BSA had approximately a 54% reduced risk of CI (odds ratio range 0.457 to 0.463). RCS analysis indicated a linear decrease in CI risk with increasing BMR metrics. …”
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Association of composite dietary antioxidant index with circadian syndrome: evidence from NHANES by Chen Chen, Chenyu Zhao, Hongyu Jin, Zhiping Jiang, Wei Wang, Wen-Yang Li

“…Logistic regression revealed that the highest quartile of CDAI was inversely associated with the risk of CircS {odds ratio (OR) [95% CI = 0.69 (0.55–0.87)]} and the risk of depression [OR = 0.59 (0.48–0.72)], short sleep duration [OR = 0.54 (0.41–0.70)], elevated fasting glucose [OR = 0.80 (0.65–0.98)], elevated triglycerides (TG) [OR = 0.74 (0.59–0.92)], elevated waist circumference [OR = 0.65, (0.52–0.80)] and reduced high-density lipoprotein cholesterol (HDL-C) [OR = 0.75 (0.61–0.92)], respectively. …”
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A nomogram model based on albumin-bilirubin score for predicting 90-day prognosis in patients with acute-on-chronic liver failure by Wei Ding, Wei Ding, Jiandong Shen, Li Zhang, Li Zhang, Jianguo Shao, Zhaolian Bian, Hong Xue

“…Model performance was assessed using receiver operating characteristic (ROC) curves, calibration curves, decision curve analysis (DCA) and the Hosmer-Lemeshow test.ResultsCreatinine (CR) [odds ratio (OR) = 1.013, 95% confidence interval (CI): 1.004–1.022], ALBI (OR = 10.831, 95% CI: 4.009–33.247), Gender (OR = 1.931, 95% CI: 0.973–3.870) and ascites (OR = 3.032, 95% CI: 1.249–8.178) were identified as independent prognostic factors. …”
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Factors associated with the injury severity of falls from a similar height and features of the injury site in Korea: a retrospective study by Dae Hyun Kim, Jae-Hyug Woo, Yang Bin Jeon, Jin-Seong Cho, Jae Ho Jang, Jea Yeon Choi, Woo Sung Choi

“…In multivariable analysis, higher height (odds ratio [OR] 1.638; 95% confidence interval [Cl], 1.279–2.098) and accompanying foot injury (OR, 0.466; 95% CI, 0.263–0.828) were independently associated with injury severity (EMR-ISS ≥25) and intentionality of fall (OR, 0.722; 95% CI, 0.418–1.248) was not associated with injury severity. …”
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Knowledge, attitude, and practice toward vocal fatigue among occupational voice users: a cross-sectional study by Zhou Zhou, Yanlu Lyu, Ming Yang, Min Yan, Zhaoyang Ke

“…A graduate degree or higher was positively associated with knowledge (odds ratio [OR] = 1.596, P = 0.007). Negative associations with knowledge included being a salesperson (OR = 0.342, P < 0.001) or a lawyer (OR = 0.150, P = 0.001). …”
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Predictors and Prognostic Effects of Perioperative Myocardial Injury After Transcatheter Aortic Valve Replacement According to VARC-3 Criteria by Hu X, Zhao Z, Wang C, Feng D, Chen Y, Niu G, Zhou Z, Zhang H, Li Z, Ye Y, Wang M, Wu Y

“…After multivariable adjustment, female sex (odds ratio [OR]: 3.01, 95% confidence interval [CI]: 1.88− 4.82, P < 0.001), anticoagulant use (OR: 0.27, 95% CI: 0.08− 0.96, P = 0.043), balloon-expandable valve (OR: 0.27, 95% CI: 0.09− 0.79, P = 0.017), and secondary valve implantation (OR: 2.66, 95% CI: 1.40− 5.03, P = 0.003) were significantly associated with PPMI. …”
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Oral health-related quality of life of community-dwellers in the canton of Bern, Switzerland by Roberta Borg-Bartolo, Andrea Roccuzzo, Christian Tennert, Maria Prasinou, Maurus Jäggi, Pedro Molinero-Mourelle, Michael M. Bornstein, Guglielmo Campus

“…Binary logistic regression shows that participants with rheumatoid arthritis (odds ratio [OR] = 4.86, 95% confidence interval [CI] = 1.70–13.87) and chewing deficiencies (OR 28.43, 95% CI = 2.11–382.68) had higher odds of having functional limitations, while participants with bleeding gums (OR = 1.69, 95% CI = 1.02–2.81) had higher odds of experiencing pain and discomfort. …”
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Construction and Validation of a Major Depression Risk Predictive Model for Patients with Coronary Heart Disease: Insights from NHANES 2005–2018 by Li-xiang Zhang, Shan-bing Hou, Fang-fang Zhao, Ting-ting Wang, Ying Jiang, Xiao-juan Zhou, Jiao-yu Cao

“…Multivariate weighted logistic regression revealed that waist circumference, smoking status, arthritis, sleep disorders, and restricted work capacity were independent risk factors for major depression (odds ratio (OR) >1, p < 0.05). The areas under the receiver operating characteristic (ROC) curve in the nomogram model for both the development and validation cohorts were 0.816 (95% confidence interval (CI): 0.776–0.857) and 0.765 (95% CI: 0.699–0.832), respectively, indicating the model possessed strong discriminative ability. …”
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Effect of perioperative methylprednisolone administration on postoperative pleural effusion in older patients with non-small cell lung cancer by Xinyu Hao, Yongxin Guo, Ziyao Xu, Yanping Song, Jingjing Liu, Likai Shi, Qiang Fu, Wenzhu Shi, Jiangbei Cao, Yanhong Liu, Li Tong, Weidong Mi

“…After adjusting all the variables and PSM, we found that intraoperative methylprednisolone was associated with a reduction in postoperative pleural effusion in older patients with non-small cell lung cancer [odds ratio (OR) = 0.48, P < 0.001; OR = 0.47, P < 0.001]. …”
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Intestinal protozoa infections and associated factors among diarrheal under-five children in Borena district, central Ethiopia by Alebie Mesfin, Woynshet Gelaye, Getaneh Alemu

“…Children whose mothers/guardians did not attend formal education were at higher risk of IPI (adjusted odds ratio (AOR) = 2.801; 95 %CI: 1.666–4.711, p < 0.001) than children from literate mothers/guardians. …”
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Lipoprotein Lipase and PPAR Alpha Gene Polymorphisms, Increased Very-Low-Density Lipoprotein Levels, and Decreased High-Density Lipoprotein Levels as Risk Markers for the Developme... by Márcia Dias Teixeira Carvalho, Diego Peres Alonso, Célia Maria Vieira Vendrame, Dorcas Lamounier Costa, Carlos Henrique Nery Costa, Guilherme Loureiro Werneck, Paulo Eduardo Martins Ribolla, Hiro Goto

“…A polymorphism analysis of the lipoprotein lipase (LPL) gene using HindIII restriction digestion (N = 156 samples) (H+ = the presence and H− = the absence of mutation) revealed an increased adjusted odds ratio (OR) of VL versus noninfected individuals when the H+/H+ was compared with the H−/H− genotype (OR = 21.3; 95% CI = 2.32–3335.3; P = 0.003). …”
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Tenecteplase vs Reteplase in Patients with Acute ST-Elevation Myocardial Infarction: A Retrospective Cohort Study by Adham Mohamed PharmD, Sara Mahmoud PharmD, Amr M. Fahmi PhD, Ahmed Mahfouz MSc, Tayseer Kanaan MD, Jihad Jaber MD, Mansour Alkhawi MD, Saleh Alkhalaf MD, Hassan Kodimi MD, Ahmed Shaaban MD, Omar Alshibli MD, Awad Almasalmeh MD, Salaheddin Arafa MD, Salah Elbdri MD, Suhail Falah MD, Fayez Altrad MD, Ezeldin Soaly MD, Rasha Elenany PharmD, Sumaya Alyafei PharmD, Abdul Rahman Arabi MD

“…The incidence of failed thrombolysis was 33.2% in the tenecteplase group compared to 20.8% in the reteplase group (adjusted odds ratio 0.53, 95% confidence interval 0.25-1.1; p = 0.089). …”
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Exploring under-five child malnutrition in Bangladesh: Analysis using the Extended Composite Index of Anthropometric Failure (ECIEF) by Farzana Akhter Bornee, Mohammad Rocky Khan Chowdhury, Badrun Naher Siddique, Baki Billah, Farjana Akter, Md Nazmul Karim

“…Mothers with no formal education (Adjusted odds ratio (AOR): 1.51, 95% CI: 1.08, 2.10), underweight mother (AOR: 1.54, 95% CI: 1.03, 1.83), poorest socio-economic status (AOR: 2.14, 95% CI: 1.64, 2.81), children age 24-35 months of age (AOR: 2.37, 95% CI: 1.97, 2.85), and fourth and above birth order children (AOR: 1.41, 95% CI: 1.16, 1.72) were identified key factors associated with childhood malnutrition while adjusting community and household level variations. …”
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IgG Glycosylation Profile and the Glycan Score Are Associated with Type 2 Diabetes in Independent Chinese Populations: A Case-Control Study by Zhiyuan Wu, Haibin Li, Di Liu, Lixin Tao, Jie Zhang, Baolu Liang, Xiangtong Liu, Xiaonan Wang, Xia Li, Youxin Wang, Wei Wang, Xiuhua Guo

“…The glycan score composed of these IgG glycans and traits showed a strong association with type 2 diabetes (combined odds ratio (OR): 3.78) and its risk factors. In the replication population, AUC of the model involving clinical traits improved from 0.74 to above 0.90, and the values of NRI and IDI were 0.35 and 0.42, respectively, with the glycan score added. …”
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