A Nomogram Model for Predicting Recurrent Coronary Thrombosis in Kawasaki Disease Patients by Zhou X, Peng Y, Yi Q

“…Independent risk factors were identified using univariate and multivariate logistic regression analyses, and a nomogram was constructed to predict recurrent coronary thrombosis.Results: Multivariate analysis showed that large coronary artery aneurysm(CAA) (Odds Ratio [OR] 4.28; 95% Confidence Interval [CI]  1.39– 13.12), saccular CAA (OR 5.03; 95% CI 1.55– 16.29), first left anterior descending (LAD) thrombosis (OR 3.90; 95% CI 1.20– 12.63), and persistent CAA (OR 43.27; 95% CI 12.23– 153.12) were independent risk factors for recurrent coronary thrombosis. …”
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Cancer incidence and the influence of immunosuppressive agents in Korean patients with systemic lupus erythematosus: a retrospective cohort study by Soo-Kyung Cho, Jung-Yong Han, Yena Jeon, Seung-Hun You, Sun-Young Jung, Eun Jin Jang, Yoon-Kyoung Sung

“…No statistically significant association was found between immunosuppressive agents and cancer development (Odds Ratio 1.03, 95% CI 0.80–1.34). Conclusion Our study shows that Korean SLE patients using immunosuppressive agents are not significantly more likely to develop cancer. …”
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The Relationship Between the Modified Glasgow Prognostic and SYNTAX Scores in Patients with Non-ST Elevation Myocardial Infarction by Ahmet KARADUMAN, Cemalettin YILMAZ, Mustafa Ferhat KETEN, Ismail BALABAN, Zeynep Esra GUNER, Mehmet CELIK

“…Those with a SYNTAX score >22 were observed to possess significantly higher levels of CRP, CRP/albumin ratio, and mean mGPS 1-2 ratios compared with those with a SYNTAX score ≤22 (all p<0.001). Smoking [odds ratio (OR): 3.341, 95% confidence interval (CI): 1.531-7.294; p=0.002], CRP/albumin ratio (OR: 4.958, 95% CI: 1.335-18.418; p=0.017), and mGPS score of 1-2 (OR: 3.121, 95% CI: 1.430-6.814; p=0.004) were independent factors used to help predict a high SYNTAX score. …”
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Efficacy of tezepelumab in patients with severe asthma and persistent airflow obstruction by Elliot Israel, Mario Castro, Christopher S. Ambrose, Jean-Pierre Llanos, Nestor A. Molfino, Nicole L. Martin, Sandhia S. Ponnarambil, Neil Martin

“…For patients with PAO at baseline, the proportion without PAO at week 52 was higher with tezepelumab (12.1%) than placebo (6.6%) (odds ratio 1.96, 95% CI: 1.30–2.94). Conclusion Tezepelumab improved lung function and reduced exacerbations versus placebo in patients with severe, uncontrolled asthma with and without PAO.…”
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Effects of Sarcopenia on Changes in the Prevalence of Patients with Depressive Mood during Inpatient Geriatric Rehabilitation by Akio Shimizu, Keisuke Maeda, Junko Ueshima, Yuria Ishida, Tatsuro Inoue, Kenta Murotani, Ayano Nagano, Naoharu Mori, Tomohisa Ohno, Ichiro Fujisima

“…The logistic regression model showed that sarcopenia negatively influenced depressive mood at discharge (odds ratio=5.460; 95% confidence interval, 2.344–13.415). …”
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Associations between autistic traits and early ear and upper respiratory signs: a prospective observational study of the Avon Longitudinal Study of Parents and Children (ALSPAC) ge... by Amanda Hall, Dheeraj Rai, Jean Golding, Yasmin Iles-Caven, Steven Gregory, Richard Maw

“…For example, for discharge of pus or sticky mucus from ears the adjusted odds ratio (aOR) for autism at 30 months was 3.29 (95% CI 1.85 to 5.86, p<0.001), and for impaired hearing during a cold the aOR was 2.18 (95% CI 1.43 to 3.31, p<0.001).Conclusions Very young children exhibiting common ear and upper respiratory signs appear to have an increased risk of a subsequent diagnosis of autism or demonstrated high levels of autism traits. …”
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Meta-Analysis of Randomized Trials: Efficacy and Safety of Colchicine for Secondary Prevention of Cardiovascular Disease by Elie Akl, Nazanin Sahami, Christopher Labos, Jacques Genest, Ali Zgheib, Nicolo Piazza, Sanjit Jolly

“…Compared with placebo or usual care, colchicine was associated with a significant risk reduction in the primary outcome (odds ratio (OR) 0.70, 95% CI 0.60 to 0.83, P<0.0001; I2=52%). …”
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HIV status and contraceptive use in Zimbabwe among sexually active adolescent girls and women: Secondary analysis of Zimbabwe Demographic Health survey data by G Musuka, G Murewanhema, Z Mukandavire, I Chingombe, D Cuadros, F Mutenherwa, T Dzinamarira, R Eghtessadi, N Malunguza, M Mapingure

“…Sexually active adolescent girls and women on the Pill and injections were less likely to be HIV-positive compared with those not using any method of contraception (odds ratio (OR)=0.54, 95% confidence interval (CI) (0.45 - 0.64), p=0.001; and OR=0.75, 95% CI (0.59 - 0.96), p=0.020, respectively). …”
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Association between Chinese visceral adiposity index and risk of new-onset hypertension in middle-aged and older adults with prediabetes: evidence from a large national cohort stud... by Lanlan Li, Lanlan Li, Linqiang Xi, Qianhui Wang

“…Multivariate logistic regression analysis indicated that participants in Q4 had a 1.91-fold greater risk of hypertension development compared to those in Q1 (odds ratio (OR): 1.91, 95% confidence interval (CI): 1.49–2.45, p &lt; 0.001). …”
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Factors Associated with Alcohol Withdrawal or Alcohol-Withdrawal Delirium among Inpatients with Alcohol Use in a General Hospital Setting: A Comparison Before and During the COVID-... by Sukrit Teeratanatorn, Woraphat Ratta-apha, Sitigarn Puangtai, Naratip Sa-nguanpanich, Nantawat Sitdhiraksa, Sirirat Kooptiwoot

“…Clinical or laboratory risk factors related to alcohol withdrawal syndrome were analyzed using Pearson’s chi-square test, t-test, odds ratio, and logistic regression analysis for each dataset. …”
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Disrupted HIV care during COVID-19 pandemic associated with increased disabilities among people living with HIV in Belize by Tracy M. Quetzal, Wei-Cheng Lo, Ya-Wen Chiu, Hung-Yi Chiou

“…After adjusting for covariates, (age, gender, employment, CD4 count, viral load, COVID-19-affected HIV care behaviours), our results showed that people living with HIV, whose HIV care behaviors were greatly affected by COVID-19, were more likely to have disabilities across various domains: physical (adjusted odds ratio (AOR): 1.61, 95% confidence interval (CI): 1.08–2.41, p = 0.018), cognitive (AOR: 2.49, 95% CI: 1.58–3.94, p < 0.001), uncertainty (AOR: 2.94, 95% CI: 1.68–5.12, p < 0.001), difficulties carrying out day-to-day activities (AOR: 1.69, 95% CI: 1.06–2.69, p = 0.027), and social inclusion challenges (AOR: 1.89, 95% CI: 1.27–2.81, p = 0.002). …”
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The effect of cheese intake on osteoarthritis: a Mendelian randomization study by Song Wen, Zehan Huang, Bin Zhang, Yuqing Huang

“…Results Our two-sample MR analysis revealed an inverse causal relationship between cheese intake and several types of OA, including self-reported OA (odds ratio (OR) = 0.96, 95% confidence interval (CI) = 0.94–0.97, p = 6.70 × 10–7), OA of the hip or knee (OR = 0.59, 95% CI = 0.48–0.72, p = 1.38 × 10–7), knee OA (OR = 0.52, 95% CI = 0.42–0.66, p = 4.11 × 10–8), and hip OA (OR = 0.72, 95% CI = 0.53–0.96, p = 0.0268). …”
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Intranasal Insulin Diminishes Postoperative Delirium and Elevated Osteocalcin and Brain Derived Neurotrophic Factor in Older Patients Undergoing Joint Replacement: A Randomized, Do... by Yang M, Zhou L, Long G, Liu X, Ouyang W, Xie C, He X

“…The secondary objective was insulin sensitivity, which was assessed using the homeostasis model Assessment of Insulin Resistance (HOMA-IR) and biomarkers, including total osteocalcin (tOC), uncarboxylated osteocalcin (ucOC), and brain-derived neurotrophic factor (BDNF).Main Results: Compared to placebo, intranasal insulin significantly reduced the incidence of delirium within 5 days after surgery (8 [8.33%] vs 23 [23.23%], P = 0.004, odds ratio [OR] = 3.33 [95% CI 1.41– 7.88]) and the severity of delirium (P< 0.001). …”
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Clinical Outcomes of COVID-19 and Impact on Disease Course in Patients with Inflammatory Bowel Disease by Panu Wetwittayakhlang, Farah Albader, Petra A Golovics, Gustavo Drügg Hahn, Talat Bessissow, Alain Bitton, Waqqas Afif, Gary Wild, Peter L Lakatos

“…Biologic therapy was held during active COVID-19 infection in 37% of patients. Age ≥55 years (odds ratio (OR): 11.1, 95% CI: 1.8–68.0), systemic corticosteroid use (OR: 4.6, 95% CI: 0.7–30.1), active IBD (OR: 3.8, 95% CI: 0.7–20.8), and comorbidity (OR: 4.9, 95% CI: 0.8–28.6) were factors associated with severe COVID-19. …”
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Practice and factors associated with sunlight exposure of infants among mothers in Ethiopia: a systematic review and meta-analysis by Shambel Dessale Asmamaw, Tibebu Habte Zewde, Abiel Teshome, Esayas Nigussie

“…The pooled prevalence with a 95% confidence interval (CI) of the meta-analysis utilizing the random effect model was displayed using forest plots, and adjusted odds ratio (AOR) was utilized to quantify the association. …”
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Retrospective evaluation of acid–base imbalances, clinicopathologic alterations, and prognostic factors in hospitalized calves with Eimeria-associated diarrhea by Andrea Urgibl-Bauer, Annette Lorch, Dana Badura, Yury Zablotski, Peter D. Constable, Florian M. Trefz

“…In addition to plasma ionized calcium [Odds ratio (OR) = 0.011] and leukocyte concentrations (OR = 1.08), recumbency (OR = 6.1), albumin (OR = 0.90), and decreased strong ion difference (OR = 0.91) were associated with mortality in a second modeling approach (sensitivity 78.7%, specificity 71.8%).ConclusionCalves with Eimeria-associated diarrhea can develop profound clinicopathologic derangements. …”
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Prevalence and Risk Factors of Work-Related Upper Extremity Disorders among University Teaching Staff in Ethiopia, 2021: An Institution-Based Cross-Sectional Study by Amensisa Hailu Tesfaye, Tesfaye Hambisa Mekonnen, Mekuriaw Alemayehu, Giziew Abere

“…The association was ascertained using an adjusted odds ratio (AOR) with a 95% confidence interval (CI) at a p value of <0.05. …”
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The clinical role of blood coagulation and platelet receptors gene allelic variants in development of Wilson’s disease by T. P. Rozina, S. V. Fastovets, E. E. Starostina, L. M. Samokhodskaya, T. N. Krasnova

“…Frequency of 5G allele of plasminogen activator inhibitor gene PAI-675 5G/4G in the group with neurologic symptoms was lower (41.17%), than in the group without symptoms of central nervous system (CNS) involvement (49.02%) (odds ratio - OR: 1.374; 95% confidence interval - CI: 0.739-2.553). …”
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Central Obesity and Associated Factors among Adult Patients on Antiretroviral Therapy (ART) in Armed Force Comprehensive and Specialized Hospital, Addis Ababa, Ethiopia by Adnan Kemal, Mohammed Ahmed, Melese Sinaga Teshome, Kalkidan Hassen Abate

“…The collected data were entered into EpiData version 3 and analyzed by SPSS version 21. An adjusted odds ratio with 95% CI was considered to declare a statistically significant association. …”
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Association of antihypertensive drug target genes with alzheimer’s disease: a mendelian randomization study by He Zheng, Chaolei Chen, Yingqing Feng

“…Results A 1-standard deviation (SD) lower expression of the angiotensin-converting enzyme (ACE) gene in blood was associated with a lower SBP of 3.92 (95% confidence interval (CI), 2.69–5.15) mmHg but an increased risk of AD (odds ratio (OR), 2.46; 95% CI, 1.82–3.33). A similar direction of association was also observed between ACE expression in prefrontal cortex (OR, 1.19; 95% CI, 1.10–1.28), frontal cortex (OR, 1.19; 95% CI, 1.11–1.27), cerebellum (OR, 1.13; 95% CI, 1.09–1.17), cortex (OR, 1.59; 95% CI, 1.33–1.28) and ACE protein levels in plasma (OR, 1.13; 95% CI, 1.09–1.17) and AD risk. …”
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