Comparison of cardiovascular risk prediction models developed using machine learning based on data from a Sri Lankan cohort with World Health Organization risk charts for predictin... by Anuradhani Kasturiratne, Hithanadura Janaka de Silva, Chamila Mettananda, Anuradha Supun Dassanayake, Norihiro Kato, Rajitha Wickremasinghe, Maheeka Solangaarachchige, Prasanna Haddela

“…We validated the 6-variable model in an external hospital-based cohort.Results Of the 2596 participants in the baseline cohort, 179 incident CVEs were observed over 10 years. WHO risk charts predicted only 10 CVEs (AUC-ROC: 0.51, 95% CI 0.42 to 0.60), while the new 6-variable ML model predicted 125 CVEs (AUC-ROC: 0.72, 95% CI 0.66 to 0.78) and the 75-variable ML model predicted 124 CVEs (AUC-ROC: 0.74, 95% CI 0.68 to 0.80). …”
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Therapeutic Effect of <italic>Self-made Wrist Joint Flexion and Extension Orthoses</italic> Combined with Routine Rehabilitation Training on Wrist Joint Spasm after Brain Infarctio... by Rui JIAO, Shangjie CHEN, Shuqian LI, Xinyan JIA, Heng LIU

“…Objective:To observe the effect of <italic>self-made wrist joint flexion and extension orthoses</italic> combined with conventional rehabilitation treatment on wrist joint spasm in convalescent patients after cerebral infarction.Methods:A total of 60 patients with cerebral infarction were randomly assigned to wrist flexion-extension orthoses group and routine rehabilitation group according to the random number table method, with 30 cases in each group. …”
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Frailty Assessment Tools in Chronic Kidney Disease: A Systematic Review and Meta-analysis by Alisha Puri, Anita M. Lloyd, Aminu K. Bello, Marcello Tonelli, Sandra M. Campbell, Karthik Tennankore, Sara N. Davison, Stephanie Thompson

“…Selection Criteria for Studies: Observational studies and randomized trials. Data Extraction: Risk and precision measurements; measurement properties. …”
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Enhancing reproductive capacity in hybrid Red Tilapia (Oreochromis niloticus ×‎ O. mossambicus) via dietary administration of date palm pollen (Phoenix dactylifera L.)‎ by Nashi K. Alqahtani, Hesham S. Ghazzawy, Roshmon Thomas Mathew, Yousef‎ Ahmed Alkhamis, Rashid Saleh Alngada, Moaheda E.H. Eissa, Sameh A. Abdelnour, Sara F. Ghanem, Layla A. Almutairi, El-Sayed Hemdan Eissa

“…The lowest values for these parameters were observed in the DPP40 group. Lipase activity was significantly improved by DPP dietary inclusion, while amylase activity remained unaffected (P > 0.05). …”
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Perbedaan Rerata Kadar Profil Lipid pada Preeklampsia dengan Kehamilan Normal pada Etnik Minangkabau by Helen Evelina Siringoringo, Yusrawati ., Eva Chundrayetti Chundrayetti

“…The objective of this study was to find out the difference of lipid profile mean level in preeclampsia and normal pregnancy at Minangkabau Ethnic. This was an observational study with cross-sectional design at  dr. …”
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Evaluation of Southern African wild edible plants for potential herb-drug interactions through ex vivo p-glycoprotein and in vitro cytochrome P450 3A4 inhibitory effects by P.S. Kheoane, K.C. Mokhetho, S. Mokhele, K.C. Mbara, C.M. Leonard, T.H. Gadaga, C. Tarirai

“…Meanwhile, Wahlengergia androsacea A.DC exhibited the most significant (p < 0.05) CYP3A4 inhibitory effect at the same concentration in intestinal microsomes. Conclusion: The observed inhibitory effects of certain wild edible plants on P-gp-mediated drug efflux and CYP3A4 drug metabolism indicate potential food/herb-drug interactions challenges for clinical practice. …”
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Capturing Bone Signal in MRI of Pelvis, as a Large FOV Region, Using TWIST Sequence and Generating a 5-Class Attenuation Map for Prostate PET/MRI Imaging by Mehdi Shirin Shandiz PhD, Hamid Saligheh Rad PhD, Pardis Ghafarian PhD, Khadijeh Yaghoubi MSc, Mohammad Reza Ay PhD

“…Despite poor correlation in the joint histogram of µ-map MR-4c versus µ-map CT-5c (R 2 > 0.78) and PET-MRAC4c versus PET-CTAC5c (R 2 = 0.83), high correlations were observed in µ-map MR-5c versus µ-map CT-5c (R 2 > 0.94) and PET-MRAC5c versus PET-CTAC5c (R 2 > 0.96). …”
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Most prevalent jobs of young master’s degree graduates by detailed field of study by Marc Frenette, Tomasz Handler

“…While there are plenty of noteworthy results in the tables, the remainder of this article will simply highlight a few key observations. Readers are invited to examine the results based on their specific interests. …”
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The Combined Effect of Garlic (Allium sativum) and Turmeric (Curcuma longa) Extracts to Reduce the Adverse Effects of Aflatoxin B1 in Rats by Hadi Sarir, Saeedeh Zakerian, masood didarkhah

“…Eight groups were tested for 28 days in the animal dissection laboratory of the Faculty of Agriculture of Birjand University, observing all ethical considerations. This study aimed to determine the synergistic effect of garlic and turmeric extracts for possible protection against injury induced by aflatoxin B1 (AFB1). …”
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Comparison of long-term ankle joint function after one-stage and staged microsurgical repair of open achilles tendon defects by Jianjie Mao, Yang Xiang, Hui Chu, GenYang Jin, Guangyan Su, Chang zeng Liu, Feng Zhu

“…In the second stage, 31 patients underwent flexor hallucis longus tendon transfer, and 35 patients underwent peroneus longus muscle tendon transfer with the lateral calcaneal artery. Observations included evaluation of the continuity and healing of the Achilles tendon via colour Doppler ultrasound 3 months postoperatively and assessment of ankle joint function 2 years postoperatively using the American Orthopedic Foot and Ankle Society ankle–hindfoot score (AOFAS) and the Achilles tendon total rupture score (ATRS). …”
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Renal dysfunction contributes to deteriorated survival outcomes in patients with upper and lower gastrointestinal bleeding: insights from a cohort study of 1160 cases by Orsolya Anna Simon, Levente Frim, Nelli Farkas, Zoltán Sipos, Nóra Vörhendi, Eszter Boros, Dániel Pálinkás, Brigitta Teutsch, Patrícia Kalló, Vivien Vass, Andrea Szentesi, Roland Hágendorn, Péter Hegyi, Bálint Erőss, Imre Szabó

“…Numerous primary (in-hospital mortality, discharge, need for endoscopic intervention, in-hospital rebleeding, length of hospitalisation, need for emergency surgery, need for endoscopic examination and need for intensive care unit) and secondary (detection of Helicobacter pylori (H. pylori), recognition of cancer as the source of bleeding, need for any kind of transfusion or clotting factor, anticoagulation therapy) outcomes were observed. Descriptive statistical tools were used to summarize our data. …”
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Algunas aplicaciones recientes de la técnica de radio ocultamiento satelital en el estudio de procesos atmosféricos by Alejandro de la Torre, Pedro Alexander, Pablo Llamedo, Rodrigo Hierro, Horacio Pessano, Andres Odiard

“…Se pondrá especial énfasis sobre las regiones montañosas de la cordillera de los Andes a latitudes medias y de la península antártica, para lo cual se analizarán individualmente eventos de RO de interés, a partir de las excepcionales características observables de OIG en dicha región. Dicho análisis será complementado con simulaciones numéricas con el modelo de mesoescala WRF, versión 3.2. y con perfiles de T de RO disponibles en las regiones de interés. …”
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Effect of Yanshiqiangxin Decoction on Cardiomyocyte Apoptosis in Heart Failure Rats Based on PI3K/Akt/Caspase-9 Signaling Pathway by ZHU Sixing, YAN Shiyun, XU Yan, QIN Yan, CHEN Liyun, JIA Meijun

“…One day after the last gavage, M-mode echocardiography [left ventricular ejection fraction (LVEF), left ventricular short-axis shortening (LVFS), left ventricular internal dimension diastole (LVIDd) and left ventricular internal dimension systole (LVIDs)] was performed through an ultra-high resolution small animal ultrasound imaging system; B-type natriuretic peptide (BNP) was measured by ELISA method; the apoptosis of cardiomyocytes was observed through laser confocal microscopy and the apoptosis index was calculated; the expression of apoptosis-related proteins Bax, Bcl-2 and PI3K/Akt/Caspase-9 signalling pathway proteins were detected by Western blot method.Results① Cardiac ultrasound test results: compared with the normal group, the left ventricular anterior wall motion waveform of the model group was not obvious, close to linear motion, and LVEF and LVFS decreased significantly (<italic>P</italic>&lt;0.05), LVIDd and LVIDs increased significantly (<italic>P</italic>&lt;0.05), the left ventricle was significantly enlarged and the contractility was reduced. …”
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Forest fire hazard assessment based on forest typology by Volodymyr P. Voron, Andriy D. Kuzyk, Sergiy V. Ivashyniuta, Yilia R. Tsipan

“…The greatest representation of fire-prone species was observed in dry pine forests (A1), where out of 11 species, 8 have a high inflammability. …”
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Le voisinage entre hommes, forêt et les chimpanzés : point de vue depuis le territoire des villageois, à l’extérieur du Parc National de Kibale by Sarah Bortolamiol, Marianne Cohen, Andrew Seguya, Richard Dumez, Sabrina Krief

“…Nous avons combiné des entretiens semi-directifs et des observations participantes (N = 42 villageois et agriculteurs, gestionnaires, employés des usines de thé) avec des relevés floristiques en lisière de forêt (N = 8 transects soit 32 relevés situés entre 0 et 150 mètres de part et d’autre de la lisière de la forêt – janvier à avril 2013) dans un Système d’Information Géographique (SIG) pour spatialiser les rapports entre les hommes que nous avons interrogés et les chimpanzés que nous étudions. …”
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Prevalence and Antimicrobial Susceptibility of Bacterial Uropathogens Isolated from Pediatric Patients at Yekatit 12 Hospital Medical College, Addis Ababa, Ethiopia by Yamirot Merga Duffa, Kumera Terfa Kitila, Dereje Mamuye Gebretsadik, Adane Bitew

“…Multidrug resistance to two or more drugs was observed in 73.7% of the bacterial isolates. Conclusion. …”
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Measurement report: Rocket-borne measurements of large ions in the mesosphere and lower thermosphere – detection of meteor smoke particles by J. Stude, J. Stude, H. Aufmhoff, H. Schlager, M. Rapp, M. Rapp, C. Baumann, F. Arnold, B. Strelnikov

“…</p> <p>Comparing our findings to proposed meteor smoke particle compounds by other authors, our observations would be consistent with magnetite, fayalite and forsterite. …”
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Designing a security-oriented leadership model of Mazandaran University of Medical Sciences by Saeid Miladigorji, Mohammad Hassan Shakki, Mojtaba Rezaei Rad

“…Based on the presented model, the central category, along with causal factors, has been observed to be effective in the security-oriented leadership model of Mazandaran University of Medical Sciences. …”
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Influence of ethnicity on cyclin-dependent kinase inhibitor efficacy and toxicity: A systematic review and meta-analysis by Roberto Buonaiuto, Aldo Caltavituro, Margherita Tafuro, Alessandra Longobardi, Giuliana Pavone, Pierluigi De Santis, Roberta Caputo, Carmine De Angelis, Lucia Del Mastro, Fabio Puglisi, Mario Giuliano, Grazia Arpino, Martina Pagliuca, Michelino De Laurentiis

“…Interestingly, a numerically higher rate of treatment-related hematological toxicity was observed in Asian patients, although no significant interethnic difference was found in the relative risk of these events. …”
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The effect of transcutaneous auricular vagus nerve stimulation on cardiovascular function in subarachnoid hemorrhage patients: A randomized trial by Gansheng Tan, Anna L Huguenard, Kara M Donovan, Phillip Demarest, Xiaoxuan Liu, Ziwei Li, Markus Adamek, Kory Lavine, Ananthv K Vellimana, Terrance T Kummer, Joshua W Osbun, Gregory J Zipfel, Peter Brunner, Eric C Leuthardt

“…Conclusions: Our study found that taVNS treatment did not induce adverse cardiovascular effects, such as bradycardia or QT prolongation, supporting its development as a safe immunomodulatory treatment approach for SAH patients. The observed acute increase in heart rate after taVNS treatment may serve as a biomarker for SAH patients who could derive greater benefit from this treatment. …”
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