Association between monocyte-lymphocyte ratio and all-cause and cardiovascular mortality in patients with chronic kidney diseases: A data analysis from national health and nutritio... by Wenwu Liu, Shuwei Weng, Chenghui Cao, Yuting Yi, Yue Wu, Daoquan Peng

“…Consistent results were also observed when MLR was examined as categorical variable (quartiles). …”
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Determination of HLA Tissue Type According to the Etiology of Patients with Chronic Renal Failure by Burcu KARAKUS TURAN, Fahri UCAR, Vural Taner YILMAZ, Yahya KILINC, Sule DARBAŞ ARAS, Huseyin KOCAK, Nurten SAYIN EKINCI, Bulent AYDINLI, Habibe Sema ARSLAN

“…Results: HLA A*02 (21.83%), B*35 (18.30%), DRB1*11 (21.41%) alleles were observed most frequently in individuals with CKD, respectively. …”
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Application of Rapid Impacts Assessment Matrix (RIAM) in Detecting Environmental Impacts of Chabahar Desalination Plant by Hasan Sayyad, Mohsen Shahriari Moghaddam, Malihe Erfani, Saeed Mohammadi

“…Considering that this complex is a significant source of drinking water for the region and has meaningful positive impacts in the economic and social sectors, the continuation of its activities is permissible as long as environmental protection measures are observed.   Discussion: It is necessary to reduce the intensity of their effects by implementing corrective actions and monitoring environmental parameters at the wastewater disposal site, as well as continuously measuring the output pollutants in the surrounding environment and comparing them with national and international standards. …”
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A retrospective multicenter study on the efficacy and safety of disitamab vedotin monotherapy versus combination with anti-PD-1 immunotherapy in advanced gastric cancer by Shuailei Dong, Chen Wei, Xueting Wang, Xinyi Yang, Wei Shen, Shuyi Li, Jiye Xu, Yijie Ma, Liangyu Bie, Wenyue Yu, Ning Li

“…No new safety risks were observed. In sum, the RC48 and anti-PD-1 IT combination showed good efficacy and a manageable safety profile, indicating its strong potential as an advanced GC therapeutic option.…”
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The Relationship of Conduction Disorder and Prognosis in Patients with Acute Coronary Syndrome by Wei-Chieh Lee, Yen-Nan Fang, Tien-Yu Chen, Yun-Yu Hsieh, Yi-Hsuan Tsai, Hsiu-Yu Fang, Po-Jui Wu, Huang-Chung Chen, Ping-Yen Liu

“…The lowest incidence of CV and all-cause mortality was observed in patients with RBBB. After adjustment of age, gender, comorbidities, medication, and mean LVEF, those with LBBB had the highest hazard ratio for major adverse cardiovascular events (MACEs) of 1.113 (p=0.029; 95% CI = 1.013–1.266). …”
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Im Niemandsland zwischen strengem Satz und Historismus. Zur Krise der Kontrapunktlehre im mittleren 19. Jahrhundert by Florian Edler

“…The influence of the music of his time on Bellermann’s method can be observed in an example from his book Der Contrapunkt, which may be interpreted as the outer voices of a modified Tristan citation.…”
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The analgesic effectiveness of auriculotherapy for acute postoperative pain: A systematic review and meta-analysis by Guilin Zhang, Guixing Xu, Yao Tang, Lingxue Zhang, Xi Chen, Xingyu Liang, Ling Zhao, Dehua Li

“…However, no significant effects were observed in reducing postoperative nausea or vomiting [RR(95 %CI)=0.61(0.32, 1.16), I2=71 %, P=0.13; RR(95 %CI)=0.32(0.09, 1.18), I2=71 %, P=0.09; RR (95 %CI)=0.34(0.11, 1.06), I2=28 %, P=0.06; for postoperative nausea and vomiting (PONV), postoperative nausea or postoperative vomiting respectively], with evidence ranging from moderate to very low. …”
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Charlson comorbidity index has no incremental value for mortality risk prediction in nursing home residents with COVID-19 disease by Anum Zahra, Maarten van Smeden, Petra J. M. Elders, Jan Festen, Jacobijn Gussekloo, Karlijn J. Joling, Anouk van Loon, Kim Luijken, René J. F. Melis, Simon P. Mooijaart, Karel G. M. Moons, Geeske Peeters, Harmke A. Polinder-Bos, Fenne Wouters, Anne de Hond

“…Methods We included older individuals of ≥ 70 years of age in a large retrospective observational cohort across NHs in the Netherlands. Individuals with PCR-confirmed COVID-19 diagnosis from 1 March 2020 to 31 December 2021 were included. …”
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A randomised, double-masked, placebo-controlled trial evaluating the efficacy and safety of teprotumumab for active thyroid eye disease in Japanese patientsResearch in context by Yuji Hiromatsu, Eri Ishikawa, Ai Kozaki, Yasuhiro Takahashi, Mika Tanabe, Ken Hayashi, Yukihiro Imagawa, Kazutoyo Kaneda, Masashi Mimura, Xiaoxian Dai, Tomoko Hayashida, Takashi Akamizu

“…No study drug-related serious AEs were observed. Funding: Horizon Therapeutics plc (now Amgen).…”
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Functional status, lymphocyte-to-monocyte ratio, and platelet-to-lymphocyte ratio as prognostic factors of one-year survival rate in elderly patients with advanced-stage non-small... by Ratna Nurhayati, Aulia Rizka, Cleopas Martin Rumende, Noorwati Sutandyo, Arif Hanafi, Edy Rizal Wahyudi, Hamzah Shatri, Anna Mira Lubis, Em Yunir, Muhammad Firdaus, Yuniar Harris Prayitno, Nadira Nibras Taqiyya

“…Significant correlations were observed between the lymphocyte-to-monocyte ratio and platelet-to-lymphocyte ratio with the 1-year survival rate in elderly patients with stage IIIB-IV NSCLC (p = 0.015 and p = 0.001, respectively). …”
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CAM/TMA-DPH as a promising alternative to SYTO9/PI for cell viability assessment in bacterial biofilms by Tinatini Tchatchiashvili, Tinatini Tchatchiashvili, Mateusz Jundzill, Mateusz Jundzill, Mike Marquet, Kamran A. Mirza, Kamran A. Mirza, Mathias W. Pletz, Mathias W. Pletz, Oliwia Makarewicz, Oliwia Makarewicz, Lara Thieme, Lara Thieme

“…In contrast, SYTO9/PI staining consistently underestimated the viability of untreated biofilms, particularly in Klebsiella pneumoniae, where a negative correlation with CFU/mL was observed (r = –0.04). Positive correlations for SYTO9/PI staining were noted in other species (r = 0.65 - 0.79). …”
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Wu-Mei-Wan enhances brown adipose tissue function and white adipose browning in obese mice via upregulation of HSF1 by Shen Chen, Kexin Nie, Hongzhan Wang, Yang Gao, Xinyue Jiang, Hao Su, Zhi Wang, Yueheng Tang, Fuer Lu, Hui Dong, Jingbin Li

“…The increase in HSF1 expression in both BAT and WAT, observed with WMW treatment, was crucial for these beneficial effects, as inhibition of HSF1 negated the positive outcomes. …”
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Core microbe Bifidobacterium in the hindgut of calves improves the growth phenotype of young hosts by regulating microbial functions and host metabolism by Yimin Zhuang, Duo Gao, Wen Jiang, Yiming Xu, Guanglei Liu, Guobin Hou, Tianyu Chen, Shangru Li, Siyuan Zhang, Shuai Liu, Jingjun Wang, Jianxin Xiao, Mengmeng Li, Wei Wang, Shengli Li, Zhijun Cao

“…Distinct differences were observed between the two clustered gut microbiomes, including microbial diversity and composition. …”
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Oxyresveratrol as a novel ferroptosis inducer exhibits anticancer activity against breast cancer via the EGFR/PI3K/AKT/GPX4 signalling axis by Lei Xiang, Qingzhou Li, Zhiwei Guan, Guilin Wang, Xiankuo Yu, Xianwen Zhang, Guochen Zhang, Jushan Hu, Xue Yang, Mingrui Li, Xilinqiqige Bao, Yumei Wang, Dong Wang

“…Ferroptosis markers (ferrous ions, reactive oxygen species, lipid peroxidation, and GPX4 expression) were assessed, and mitochondrial morphology was observed. The effect of ORes on tumour growth was evaluated in vivo, along with the analysis of ferroptosis in tissues. …”
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Frequency of consumption and factors associated with hookah use in Curitiba, Brazil: a cross-sectional study by Heloisa Franco de Meira, Paulo Henrique Couto Souza, Juliana Schaia Rocha Orsi, Fernanda Tiboni, Sérgio Aparecido Ignácio, Constanza Andrea Hernandez Meza, Flávia Sukekava, Arieli Carini Michels, Amanda Dallegrave Vicentin, Patricia Lupion Torres, Emanuela Carla dos Santos, Mariana Hornung Marins, Aldini Beuting Pereira, Paula Cristina Trevilatto, Aline Cristina Batista Rodrigues Johann

“…Higher values for high consumption compared to low consumption were observed in individuals aged up to 22 years, those with high school education, and those who purchase hookah essence from a distributor. …”
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Safety and efficacy of edoxaban monotherapy after bioabsorbable polymer everolimus-eluting stent implantation in a human-like coronary atherosclerotic porcine model by Daisuke Kitano, Suguru Migita, Yuxin Li, Yutaka Koyama, Katsunori Fukumoto, Sayaka Shimodai-Yamada, Akira Onishi, Daiichiro Fuchimoto, Shunichi Suzuki, Yoshiyuki Nakamura, Atsushi Hirayama, Hiroyuki Hao, Yasuo Okumura

“…No in-stent thrombi were observed in either group. iMap-IVUS findings indicated that edoxaban monotherapy significantly suppressed the increase in lipidic and necrotic plaque area while promoting fibrotic area expansion. …”
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Analysis of drought and extreme precipitation events in Thailand: trends, climate modeling, and implications for climate change adaptation by José Francisco de Oliveira-Júnior, David Mendes, Helder Dutra Porto, Kelvy Rosalvo Alencar Cardoso, José Augusto Ferreira Neto, Emannuel Bezerra Cavalcante da Silva, Marlúcia de Aquino Pereira, Monica Cristina Damião Mendes, Bernardo Bruno Dias Baracho, Punyawi Jamjareegulgarn

“…Historically, the CWD indicated consecutive wet days in the N and NE, whereas in the R4.5 and R8.5 scenarios, this was observed only in the Central and Southern regions. …”
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Predictors of Colorectal Cancer Screening and Screening Modalities among Patients seen at Federally Qualified Health Centers Funded by the United States Health Resources and Servic... by Megan R.M. Aaronson, Nadereh Pourat, Connie Lu, Jayraan Badiee, Helen Yu-Lefler, Benjamin Picillo, Hank Hoang, Folasade P. May

“…Selected factors associated with any CRC screening included having five or more health center visits in the past year (aOR = 1.66, 95 %CI = 1.07–2.56), being insured (Medicaid aOR = 2.25, 95 %CI = 1.44–3.54; other insurance aOR = 2.69, 95 %CI = 1.51–4.82), living within 30  minutes of the health center (aOR = 1.93, 95 %CI = 1.15–3.25), having multiple comorbidities (aOR = 1.72, 95 %CI = 1.13–2.63), using telehealth (aOR = 1.52, 95 %CI = 1.02–2.27), and having a flu shot last year (aOR = 1.77, 95 %CI = 1.29–2.45). We observed that patients who are non-Hispanic Black (aOR = 3.52, 95 %CI = 1.28–9.68) and who do not speak English well or at all (aOR = 5.54, 95 %CI = 1.64–18.75) reported having multiple modalities. …”
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Role of Virtual iMRI in Glioblastoma Surgery: Advantages, Limitations, and Correlation with iCT and Brain Shift by Erica Grasso, Francesco Certo, Mario Ganau, Giulio Bonomo, Giuseppa Fiumanò, Giovanni Buscema, Andrea Maugeri, Antonella Agodi, Giuseppe M. V. Barbagallo

“…A statistically significant reduction towards lower TRE values after EIF was observed for test structures. <b>Conclusions</b>: Virtual iMRI was proven to be a feasible option to detect residual tumour. …”
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Exploring sex differences in Alzheimer’s disease: a comprehensive analysis of a large patient cohort from a memory unit by Maitee Rosende-Roca, Fernando García-Gutiérrez, Yahveth Cantero-Fortiz, Montserrat Alegret, Vanesa Pytel, Pilar Cañabate, Antonio González-Pérez, Itziar de Rojas, Liliana Vargas, Juan Pablo Tartari, Ana Espinosa, Gemma Ortega, Alba Pérez-Cordón, Mariola Moreno, Sílvia Preckler, Susanna Seguer, Miren Jone Gurruchaga, Lluís Tárraga, Agustín Ruiz, Sergi Valero, Mercè Boada, Marta Marquié

“…Similarly, the decline in most neuropsychological functions assessed by NBACE did not exhibit significant differences between males and females. However, we observed that women diagnosed with mild AD dementia progressed more rapidly based on their CDR score (HR = 2.57, 95%CI:2.33–2.84) than men (HR = 2.03, 95%CI: 1.71–2.41) (p-interaction = 0.01). …”
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