Perbandingan Reaksi Zat Besi Terhadap Teh Hitam dan Teh Hijau Secara In Vitro dengan Menggunakan Spektrofotometer Uv-Vis by Husnil Wardiyah, Yustini Alioes, Dian Pertiwi

“…Black tea and green tea were observed in this research since these are widely consumed by public. …”
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Oxidative balance score was negatively associated with the risk of metabolic syndrome, metabolic syndrome severity, and all-cause mortality of patients with metabolic syndrome by Zhixiao Xu, Xiong Lei, Weiwei Chu, Luoqi Weng, Chengshui Chen, Chengshui Chen, Chengshui Chen, Ran Ye

“…There existed a statistically significant negative correlation between diet/lifestyle OBS and both MetS risk as well as MetS severity.ConclusionsAn inverse correlation was observed between OBS and the susceptibility to MetS, MetS severity, and all-cause mortality of MetS patients. …”
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Baseline 18F-FDG PET/CT parameters in predicting the efficacy of immunotherapy in non-small cell lung cancer by Lu Zheng, Lu Zheng, Yanzhu Bian, Yanzhu Bian, Yujing Hu, Congna Tian, Xinchao Zhang, Shuheng Li, Xin Yang, Yanan Qin

“…Multivariate Cox proportional hazards regression analysis was conducted with parameters significantly associated with survival in univariate analysis.ResultsSignificant differences were observed in PFS (χ2 = 11.910, p = 0.0006) and OS (χ2 = 8.343, p = 0.0039). …”
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Determining whether ethnic minorities with severe obesity face a disproportionate risk of serious disease and death from COVID-19: outcomes from a Southern California-based retrosp... by Qiaowu Li, Hemesh Mahesh Patel, Shefali Khandwala, Poonam Somani, Stephanie Tovar, Alejandra Montano

“…A similar trend was observed with invasive ventilation risk. The risk of death was greater in Asian (RR 3.96, 95% CI 1.88 to 8.33; p<0.001), Hispanic (RR 3.03, 95% CI 2.53 to 3.61; p<0.001) and Pacific Islander (RR 4.60, 95% CI 1.42 to 14.92; p=0.011) patients compared with White (RR 1.47, 95% CI 1.13 to 1.91; p=0.005) and Black (RR 2.83, 95% CI 1.99 to 4.02; p<0.001) patients with a BMI over 45 kg/m².Conclusions Ethnic minorities with severe obesity, particularly Asian, Hispanic and Pacific Islander patients, had a statistically significant higher risk of hospitalisation, invasive ventilator use and death due to COVID-19. …”
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Adjuvant-free, self−assembling ferritin nanoparticle vaccine coupled with influenza virus hemagglutinin protein carrying M1 and PADRE epitopes elicits cross-protective immune respo... by Yongqiang Zhao, Shuangshuang Guo, Jia Liu, Yating Wang, Bo Wang, Chun Peng, Enqi Du, Enqi Du, Enqi Du

“…And neutralization titers induced by HMP-NPs against the H3N2 virus and heterologous strains of the H1N1 and H9N2 viruses were ~8, 12.4 and 16 times higher than inactivated influenza vaccine, respectively. Meanwhile, we also observed that the number of IFN-γ- and IL-4-secreting cells induced by HMP-NPs were ~2.5 times higher than inactivated influenza vaccine. …”
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Real-World Persistence and Effectiveness of Upadacitinib versus Other Janus Kinase Inhibitors and Tumor Necrosis Factor Inhibitors in Australian Patients with Rheumatoid Arthritis by Peter Youssef, Sabina Ciciriello, Talib Tahir, Joanna Leadbetter, Belinda Butcher, Miriam Calao, Nicole Walsh, Catherine O’Sullivan, Tegan Smith, Geoffrey Littlejohn

“…The DAS28CRP(3) remission rate was 73% at 3 months, with improvements observed across lines of therapy. UPA monotherapy and combination therapy had similar persistence (27.8 [23.5, 33.4] versus 30.4 months [22.1, 35.3], p = 0.84) and effectiveness. …”
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Activation of Hippocampal Microglia Mediates Chronic Stress-induced Depression-like Behavior in Rats with Ischemic Stroke by TAO Xi, YANG Chen, TANG Wenjing, WU Siyuan, DENG Jinggui

“…Four weeks after MCAO, compared with the 4-week stroke group, decreases in the body weight, SPI and counts of rearing and grid crossing of OFT, and extended latency and reduced food intake of NSFT were observed in the 3-week stress group (all <italic>P</italic>&lt;0.05). …”
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Reciprocal regulation between DNMT3A/3B and microRNAs miRs-299-3p/-30e is a causal factor for the downregulation of microRNAs targeting androgen receptor in prostate cancer by Kavya Ganapathy, Christian F. Harrs, Samuel Harris, Stephen J. Staklinski, Ayman Khatib, Jong Y. Park, Ratna Chakrabarti

“…We performed DNMT activity assays and ectopic expression of miRNAs to study their effects. Results: We observed higher promoter methylation of these miRNA genes in cells derived from an AA patient compared to cells of CA origin, which can be reversed through AzaC treatment. …”
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Large-scale evidence generation and evaluation across a network of databases for type 2 diabetes mellitus (LEGEND-T2DM): a protocol for a series of multinational, real-world compar... by Rohan Khera, Yuan Lu, Harlan M Krumholz, Martijn J Schuemie, Ruijun Chen, George Hripcsak, Marc A Suchard, Patrick B Ryan, Anna Ostropolets

“…LEGEND-T2DM will leverage the Observational Health Data Sciences and Informatics (OHDSI) community that provides access to a global network of administrative claims and electronic health record data sources, representing 190 million patients in the USA and about 50 million internationally. …”
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Radiogenomics and machine learning predict oncogenic signaling pathways in glioblastoma by Abdul Basit Ahanger, Syed Wajid Aalam, Tariq Ahmad Masoodi, Asma Shah, Meraj Alam Khan, Ajaz A. Bhat, Assif Assad, Muzafar Ahmad Macha, Muzafar Rasool Bhat

“…Disruptions in various oncogenic signaling pathways, such as Receptor Tyrosine Kinase (RTK)-Ras-Extracellular signal-regulated kinase (ERK) signaling, Phosphoinositide 3- Kinases (PI3Ks), tumor protein p53 (TP53), and Neurogenic locus notch homolog protein (NOTCH), contribute to the development of different tumor types, each exhibiting distinct morphological and phenotypic features that can be observed at a microscopic level. However, identifying genetic abnormalities for targeted therapy often requires invasive procedures, prompting exploration into non-invasive approaches like radiogenomics. …”
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Effect of temporal water restrictions on drinking behavior and time budget in lactating dairy cows according to their position in the social hierarchy within the herd by E. Nizzi, O. Dhumez, C. Hurtaud, A. Boudon

“…Hourly lying time decreased at the end of the water restriction periods, that is, at 1000 h in HL, at 1100 h in D2H, and at 1200 and 1300 h in D4H, which was not observed in CTRL, which could be interpreted as a sign of cow discomfort. …”
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A green forage diet enhances microbial diversity in buffalo rumen by Angela Salzano, Giovanna Bifulco, Alfio Calanni Macchio, Valentina Longobardi, Francesca Aragona, Giovan Maria Pacelli, Giuseppe Campanile

“…Al though the abundant microbial taxa of the rumen are not affected by the experimental diet, we observed a significant increase in rare species and an overall increase in total biodiversity in the Green group. …”
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The Degree of Cervical Intervertebral Disc Degeneration Is Associated With Denser Bone Quality of the Cervical Sub‐endplate and Vertebral Body by Jia‐Yu Chen, Jia‐Chen Yang, Ruo‐Yao Li, Zu‐Cheng Huang, Zhi‐Ping Huang, Xiu‐Hua Wu, Qing‐An Zhu, Yin Ding

“…Negative correlations were observed between both cranial and caudal VBQ and EBQ scores and Pfirrmann grades. …”
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Hubungan Tingkat Kemandirian dalam Melakukan Aktivitas Kehidupan Sehari-Hari dan Status Gizi pada Usia Lanjut di Panti Sosial Tresna Werdha Sabai Nan Aluih Sicincin by Afifah Alfyanita, Rose Dinda Martini, Husnil Kadri

“…The objective of this study was to determine the relationship between the level of independence in performing ADL and nutritional status of elderly.This research was an observational analytical study which designed as cross-sectional study. …”
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Burden of chronic obstructive pulmonary disease attributable to ambient ozone pollution across China and its provinces, 1990–2021: An analysis for the Global Burden of Disease Stud... by Yixuan Jiang, Fanshu Yan, Haidong Kan, Maigeng Zhou, Peng Yin, Renjie Chen, Jing Ni

“…Generally, a higher burden was observed among males, the elderly, and the population residing in regions with worse health conditions. …”
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A PEDAGOGIA DA ALTERNÂNCIA COMO PROPOSTA DE EDUCAÇÃO NO CAMPO: UM ESTUDO NA ESCOLA FAMÍLIA AGRÍCOLA ITAPIREMA EM RONDÔNIA, BRASIL by Claudineia Ferreira dos Santos, Charles Carminati de Lima, Yanet Reimondo Barrios, Daniete Fernandes Rocha

“…From the results, it was possible to observe the predominant option in studying at the Agricultural Family School (EFA Itapirema) because the school has a technical course of professional preparation. …”
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Short-term Effects of Sling Exercise Combined with Massage on the Treatment of Neck Type Cervical Spondylopathy by LI Jianfei, ZHAO Hong, CHEN Qian, LI Li, ZHANG Deqi

“…Objective: To observe the effects of sling exercise combined with massage in patients with neck type cervical spondylopathy (NTCS) by using surface electromyography (sEMG), and to explore the short-term effects on neck pain, neck disabilities and muscle fatigue.MethodsA total of ninety-three patients with neck type cervical spondylopathy who met the inclusion criteria were divided into three groups according to the random number table: massage group, sling exercise group and sling exercise combined with massage group, with 31 cases in each group. …”
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Safety profile of sacituzumab govitecan in patients with breast cancer: A systematic review and meta-analysis by Maria Inez Dacoregio, Isabella Michelon, Caio Ernesto do Rego Castro, Francisco Cezar Aquino de Moraes, Guilherme Rossato de Almeida, Lis Victória Ravani, Maysa Vilbert, Ricardo Lima Barros Costa

“…Compared to TPC, we observed a higher risk of neutropenia (OR 3.11, 95 % CI 1.62–5.99, I2 = 81 %; p < 0.001), diarrhea (OR 6.82, 95 % CI 3.99–11.66, I2 = 64 %; p < 0.001) and anemia (OR 2.26, 95 % CI 1.20–4.27, I2 = 78 %; p = 0.012) for those on SG. …”
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Long-Term Real-World Outcomes of Tenofovir Alafenamide in Chronic Hepatitis B: Detailed Analysis of Treatment-Naive and Experienced Patients by Yu-Xuan Song, Guang-Jun Song, Hui Ma, Bo Feng, Yan-Di Xie

“…A significant decrease in the HBsAg levels from the baseline was observed at 144 and 192 weeks in the treatment-naive patients (p=0.01). …”
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Combination of Metformin and Magnesium Citrate Reduces TNF-α, NF-κB p65, IL-6, CD4, and MMP-9 Expressions in Diabetic Model Rats by Rachmi Fauziah Rahayu, Adi Prayitno, Bambang Purwanto, Widiastuti Soewondo, Ida Nurwati, Eti Poncorini Pamungkasari, Paramasari Dirgahayu

“…RESULTS: Significant differences in TNF-α, NF-κB p65, IL-6, CD4, and MMP-9 expression levels were observed across all groups (p<0.001). The combination therapy group demonstrated the most significant reduction in all parameters compared to the diabetic control group (p<0.001) and other therapy groups. …”
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