Quality of life in early breast cancer patients after adjuvant accelerated partial-breast irradiation (APBI) in randomized trial by Petr Burkon, Iveta Selingerova, Miroslav Vrzal, Milos Holanek, Oldrich Coufal, Katerina Polachova, Vera Andraskova, Sachin R. Jhawar, Pavel Slampa, Tomas Kazda, Marek Slavik

“…Significant between-group differences were observed for the pain (p = 0.002), systemic therapy side effects (p = 0.004), and breast symptoms (p < 0.001) scales at M0, with higher scores in the WBI arm. …”
Get full text

Efficacy and safety of SHEN26, a novel oral small molecular RdRp inhibitor for COVID-19 treatment: a multicenter, randomized, double-blinded, placebo-controlled, phase II clinical... by Jiangtao Bai, Tetsuya Asakawa, Wenfang Yuan, Yuanlong Lin, Hao Ju, Dandan Xu, Mingming Yang, Shuo Li, Guanguan Li, Deyin Guo, Hongzhou Lu, Xumu Zhang

“…No significant differences in the baseline data were observed between the groups. The changes of viral load were significantly higher on D3 (P = 0.0119), and D5 (P = 0.0120) in 400 mg group (vs. placebo group), and the difference value achieved 1.06 log10 copies/mL on D3 and 1.21 log10 copies/mL on D5. …”
Get full text

Meta Analysis of Methylenetetrahydrofolate Reductase (MTHFR) C677T polymorphism and its association with folate and colorectal cancer by Meng Ye, Guojie Xu, Liming Zhang, Zhihui Kong, Zhenhua Qiu

“…A negative correlation between TT genotype and CRC was observed in ethnics of Asians (OR = 0.83, 95% CI: 0.76, 0.91), Caucasians (OR = 0.93, 95% CI: 0.88, 0.99) and the region of USA (OR = 0.77, 95% CI: 0.71, 0.85), Asia (OR = 0.93, 95% CI: 0.86, 1.00) and Europe (OR = 0.93, 95% CI:0.87, 1.00),but not in Indian (TT: OR = 1.67, 95% CI: 1.06, 2.63; CT: OR = 1.31, 95% CI: 1.00, 1.73)). …”
Get full text

Behavioral risk factors and socioeconomic inequalities in ischemic heart disease mortality in the United States: A causal mediation analysis using record linkage data. by Yachen Zhu, Laura Llamosas-Falcón, William C Kerr, Jürgen Rehm, Charlotte Probst

“…In both males and females, clear socioeconomic gradients in IHD mortality were observed, with low- and middle-education people bearing statistically significantly higher risks compared to high-education people. …”
Get full text

One-Year Review Of Reduced Fetal Movements In Izzat Ali Shah MCH Center: A Predictor Of Poor Perinatal Outcome by Humera Rani, Gulwish Salahuddin, Ayesha Naz, Noreen Majeed, Faiza Safdar, Shazia Rafique

“…Methodology: This Prospective, Observational study was conducted at Izzat Ali Shah Maternal and child health center, unit III Gynae, Wah medical college Wah Cantt, from January 2019 to December 2019. …”
Get full text

Regulatory T Cell Phenotype Related to Cytokine Expression Patterns in Post‐COVID‐19 Pulmonary Fibrosis and Idiopathic Pulmonary Fibrosis by Sara Gangi, Laura Bergantini, Irene Paggi, Marco Spalletti, Paolo Cameli, Elena Bargagli, Miriana d'Alessandro

“…Results Higher CD8 percentages were observed in IPF than in HCs and PCLF (p = 0.020 and p = 0.007, respectively). …”
Get full text

Associated adverse outcomes with tumor treating fields when combined to temozolomide versus temozolomide alone for the treatment of glioblastoma: a meta-analysis of randomized tria... by Yuanyuan Chen, Yan Chen, Hong Zhen, Danhua Lou

“…Similar adverse effects were observed. Conclusion TTF in combination with temozolomide was not associated with significantly worse adverse outcomes for the treatment of patients with glioblastoma. …”
Get full text

Early Weaning Impairs the Growth Performance of Hu Lambs Through Damaging Intestinal Morphology and Disrupting Serum Metabolite Homeostasis by Haoyun Jiang, Haibo Wang, Haobin Jia, Yuhang Liu, Yue Pan, Xiaojun Zhong, Junhong Huo, Jinshun Zhan

“…As for the serum parameters, the concentrations of glucose on D33, D36, and D45 (<i>p</i> < 0.001), and the IL-6 content on D45 (<i>p</i> = 0.018) were observed to be lower, while the levels of immunoglobulin A (IgA) (<i>p</i> = 0.027), IgG (<i>p</i> = 0.035), and IgM (<i>p</i> = 0.002) on the four ages were all higher in the EW group than those in CON group. …”
Get full text

Hypofractionated image-guided radiotherapy with 70 Gy in 28 fractions for prostate cancer confined to the pelvis: a single institute experience in Taiwan by Hui-Lei Mu, Mau-Shin Chi, Hui-Ling Ko, Guang-Dar Juang, Thomas I-Sheng Hwang, Kwan-Hwa Chi, Kai-Lin Yang

“…Grade ≥ 2 late GI toxicity was rare (0.7%), and grade ≥ 2 late GU toxicity was observed in 9.3% of the patients. Conclusions Hypofractionated image-guided radiotherapy, delivering 70 Gy at 2.5 Gy per fraction, is both effective and safe for Taiwanese patients with prostate cancer across all risk groups, consistent with findings from existing large randomized trials. …”
Get full text

Microwave Ablation of T1a and T1b Renal Masses: A Retrospective Study by Assim Saad Eddin, Karan Rao, Bradford Oliva, Ajmain Chowdhury, Shetty Zubin, Chad Tracy, Brian J. Smith, Sandeep T. Laroia

“…Furthermore, local tumor recurrence was observed in three (6.1%) patients at 2.5, 15, and 25 months postablation. …”
Get full text

Evolution of the microbiota of wound infections in military personnel during the full-scale russian invasion: a retrospective cohort study (2022–2024) by N.A. Beley, O.A. Loskutov, A.M. Strokan, O.B. Izmaylova

“…Other pathogens were observed with a proportion of < 5 %. Monomicrobial cultures accounted for 50.5 % (95% CI 47.8–53.3), two isolates were found in 34.0 % (95% CI 31.4–36.6), three isolates — in 12.7 % (95% CI 10.9–14.5), four isolates — in 2.2 % (95% CI 1.4–3.0) and five isolates — in 0.6 % (95% CI 0.3–1.1) of all cultures. …”
Get full text

Gene content of seawater microbes is a strong predictor of water chemistry across the Great Barrier Reef by Marko Terzin, Steven J. Robbins, Sara C. Bell, Kim-Anh Lê Cao, Renee K. Gruber, Pedro R. Frade, Nicole S. Webster, Yun Kit Yeoh, David G. Bourne, Patrick W. Laffy

“…Distinct seasonal variations in surface water chemistry were observed, with nutrient concentrations up to threefold higher during austral summer, explained by enhanced production of particulate organic matter (POM) by photoautotrophic picocyanobacteria, primarily Synechococcus. …”
Get full text

The Explo’Santé mixed methods protocol: an interventional research school health promotion project in France by Matteo Olivo, Adeline Darlington-Bernard, Corélie Salque, Laurie Fraticelli, Emmanuel Ricard, Florence Carrouel, Emily Darlington

“…Methods Explo’Santé is an observational study based on a mixed methods research design, which aims to evaluate the effects of a health promotion programme, to elicit its implementation process and identify contextual factors. …”
Get full text

A cross-sectional study exploring the predictors of herpes zoster vaccination for people aged over 50 years old in Chaoyang district, Beijing by Jiao Zhang, Shuo Zhang, Bin Jia, Yunhua Bai, Zhen Li, Fang Liu, Yingxue Hu, Xiaojing Guo, Jianxin Ma, Shuming Li, Qian Shi

“…On the other hand, higher vaccination coverage was observed among individuals whose spouses had a master’s degree or higher, those awarded that a history of chickenpox may lead to potential herpes zoster infection, those who were knowledgeable about the herpes zoster vaccine, and those received recommendations from medical staff. …”
Get full text

RETRACTED: Long non‐coding RNA Sox2OT promotes coronary microembolization‐induced myocardial injury by mediating pyroptosis by Liying Xuan, Danni Fu, Dong Zhen, Dongsong Bai, Lijun Yu, Guohua Gong

“…Rat cardiac functions and MI were observed by ultrasonic electrocardiogram, HE staining, and HBFP staining. …”
Get full text

Mortality risk prediction model in AIDS patients with pneumocystis pneumonia in China by Xi Wang, Letian Liu, Wen Wang, Yang Zhang, Hui Chen, Zhangli Wang, Jianwei Li, Yue Gao, Yanqun Huang, Lijun Sun, Tong Zhang, Aixin Li

“…We aimed to develop a risk model for the near-term prognosis of people with HIV/AIDS and PCP and verify its effectiveness.MethodsThis single-center, retrospective observational study was conducted at Beijing Youan Hospital from January 2012 to October 2022. 972 AIDS patients with Pneumocystis pneumonia met our criteria were recruited. …”
Get full text

Association between the hemoglobin A1c/High-density lipoprotein cholesterol ratio and stroke incidence: a prospective nationwide cohort study in China by Chaojuan Huang, Hongtao You, Yuyang Zhang, Ligang Fan, Xingliang Feng, Naiyuan Shao

“…Consistent associations were observed across most stratified subgroups. Conclusions Elevated baseline and cumulative mean HbA1c/HDL-C levels are significantly associated with an increased risk of stroke among middle-aged and older individuals in China, underscoring the potential of HbA1c/HDL-C as a clinical marker for long-term stroke risk assessment and prevention strategies.…”
Get full text

Morphological characterization and yield of pepper (Piper nigrum L.) types grown in Morogoro District, Tanzania by Abdul Jafari Shango, Ramadhani Omari Majubwa, Amon Petro Maerere

“…Methods The evaluation of pepper morphological characters was conducted following a randomized complete block design with three replications and four treatments (pepper types). Observations were recorded with respect to 28 characters (9 qualitative and 19 quantitative) which entail vegetative (8) and reproductive (20) traits. …”
Get full text

La transformation de l’ancien centre de détention secrète de Derb Moulay Cherif en musée des « années de plomb » (Casablanca, Maroc) by Anissa Habane

“…Drawing on the accounts of detainees during the "Years of Lead", scientific papers, written documents and recordings of conferences related to the issue at stake, as well as field observations and several semi-guided interviews conducted in 2023, I will reflect on three different temporalities. …”
Get full text

Evaluating choroidal vascular changes in young adults with high myopia utilizing swept source optical coherence tomography angiography by Qing wang, Lin-Bo He, Sha Li, Hong-Ling Liu, Yong Liu

“…Moreover, gradual decrease of the DCP was observed with aging(sβ=-0.227, p = 0.004). CSHL density subfoveal increased with the increase in AL(sβ=0.318, p = 0.007). …”
Get full text