Excessive occupational sitting increases risk of cardiovascular events among working individuals with type 1 diabetes in the prospective Finnish Diabetic Nephropathy Study by Matias Seppälä, Heidi Lukander, Johan Wadén, Marika I. Eriksson, Valma Harjutsalo, Per-Henrik Groop, Lena M. Thorn, FinnDiane Study Group

“…Our aim was to identify clinical factors associated with excessive occupational sitting in type 1 diabetes and, in a prospective setting, to explore its association with cardiovascular events and all-cause mortality, independent of leisure-time physical activity. Methods An observational follow-up study of 1,704 individuals (mean age 38.9 ± 10.1 years) from the Finnish Diabetic Nephropathy Study. …”
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Acute Concurrent Exercise Improves Inhibitory Control Without Mediating the Role of Lactate: An Event-Related Potential Study by Ruei-Hong Li, Tai-Rui Chen, Nicholas D. Gilson, Marius Brazaitis, Yi-Ting Cheng, Hui-Fang Wu, Ji-Hang Lee, Yu-Kai Chang

“…A decrease in P3 amplitude was observed for the CE group compared to the AE and CON groups. …”
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Effectiveness of potent topical corticosteroids versus mild ones in primary care for children with moderate flare-ups of atopic dermatitis; results of a randomised controlled trial by Patrick J E Bindels, Arthur M Bohnen, Gijs Elshout, Suzanne G M A Pasmans, Karlijn F van Halewijn

“…Objective To assess the effectiveness of a potent topical corticosteroid (TCS) as an initial treatment in primary care for children with moderate flare-ups of atopic dermatitis (AD), compared to starting on a mild TCS.Design An observational prospective cohort study with an embedded pragmatic multicentre open-label randomised controlled trial.Setting A total of 53 general practices in the southwest of the Netherlands took part in the study.Participants 209 children aged 3 months to 17 years diagnosed with AD (International Classification of Primary Care codes S87 or S88) who visited their general practitioner (GP) for AD or received repeat prescriptions for AD in the previous 12 months were included in the cohort study through the general practices. …”
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miRNA-541-5p regulates myocardial ischemia–reperfusion injury by targeting ferroptosis by ZhiYu Zhao, BoXia Li, DianWei Cheng, YuFang Leng

“…TTC staining evaluated infarction size. HE staining observed histopathological changes. DCFH-DA fluorescent probe detected ROS. …”
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The Anthelmintic Activity of <i>Nepeta racemosa</i> Lam. Against Gastrointestinal Nematodes of Sheep: Rosmarinic Acid Quantification and In Silico Tubulin-Binding Studies by Büşra Karpuz Ağören, Mahmut Sinan Erez, Esma Kozan, Aydın Dağyaran, Mevlüt Akdağ, Eduardo Sobarzo-Sánchez, Esra Küpeli Akkol

“…The EtOAc subextract shows the highest effectiveness at 79.66%, followed by the MeOH extract at 74.00%, water at 64.00%, <i>n</i>-hexane at 67.00%, and DCM at 61.00%, and the lowest effectiveness is observed with <i>n</i>-BuOH at 51.66% in the larval motility assay. …”
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Migrasomes derived from human umbilical cord mesenchymal stem cells: a new therapeutic agent for ovalbumin-induced asthma in mice by Weifeng Gu, Tingting Zheng, Wen Li, Xinkai Luo, Xiaowei Xu, Ying Wang, Chaoming Mao, Yongbin Ma, Liyang Dong

“…The administration of hUCMSC-migrasomes was observed to significantly ameliorate the symptoms of airway inflammation and mucus production in asthmatic mice. …”
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Coûts de la monopolisation des femelles et investissements reproductifs des mâles macaques crabiers (Macaca fascicularis) : importance de la valeur sociale et reproductive des feme... by Cédric Girard‑Buttoz, Michael Heistermann, Muhammad Agil, Panji Ahmad Fauzan, Antje Engelhardt

“…Nous avons combiné des observations comportementales sur l’activité des mâles avec des mesures hormonales non-invasives de glucocorticoïdes fécaux (fGC). …”
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Immunological mechanisms of tuberculosis susceptibility in TB-infected individuals with type 2 diabetes mellitus: insights from mycobacterial growth inhibition assay and cytokine a... by Bindu Dasan, Anuradha Rajamanickam, Arul Nancy Pandiarajan, Sivakumar Shanmugam, Sujatha Nott, Subash Babu

“…These findings suggest that MGIA holds promise as an in vitro marker for assessing M.tb immunological control in TBI individuals, particularly those with T2DM. The observed cytokine profile in TBI-T2DM individuals indicates a compromised immune response against M.tb activation, potentially explaining the heightened risk of active TB in this population.IMPORTANCEThis study is important because it sheds light on the impaired immune response in individuals with type 2 diabetes mellitus (T2DM) who are infected with Mycobacterium tuberculosis (M.tb), offering critical insights into why they are at higher risk of developing active tuberculosis (TB). …”
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Assessing five-year trend and socio-demographic determinants of caesarean section delivery in Ghana by Alfred Kwesi Manyeh, Anthony Ofosu, Anthony Kolsabilik Kuug, Atsu Ayi, Comfort Dede Tetteh, Saviour Edem Vidzro, Christopher Tetteh Odopey, Angela Nana Esi Ackon, Evelyn Acquah, Desmond Klu, Mustapha Immurana, Maxwell Ayindenaba Dalaba, Hubert Amu

“…Most of the deliveries occurred in hospitals and government-owned facilities. The study also observed that more than half of the women had a C-section delivery, with the highest percentage occurring in 2019 and 2020. …”
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Restraint stress effects on glutamate signaling protein levels in the rats’ frontal cortex: Does β1 adrenoceptor activity matter? by Agnieszka Zelek-Molik, Anna Gądek-Michalska, Michał Wilczkowski, Adam Bielawski, Katarzyna Maziarz, Grzegorz Kreiner, Irena Nalepa

“…The impact of RS and BET on the expression of p(Y530)/t Fyn and p (S133)/t CREB in the mPFC was measured via Western blotting.Results and DiscussionThe first part of the study demonstrated a decreased level of glutamate receptors in rats exposed to 14 days of RS, following an initial increase observed after 7 days of RS. Results from the second part revealed that chronic RS reduced body weight, impaired recognition memory in the NOR test, augmented blood levels of ACTH, and increased the expression of p(Y530) Fyn in the mPFC. …”
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Investigation of gut microbiota in pediatric patients with peanut allergy in outpatient settings by Shouming Li, Jingyi Huang, Yunyun Xie, Di Wang, Xin Tan, Yufan Wang

“…Blood routine indicators were also found to be correlated with gut microbiota composition.ConclusionThe findings of this study provide compelling evidence that gut microbiota diversity and composition are significantly altered in children with peanut allergy. The observed shifts in microbial communities, particularly the increase in Proteobacteria and the decrease in beneficial bacteria such as Firmicutes and Bacteroidetes, underscore the potential role of the gut microbiome in the pathogenesis of peanut allergy. …”
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Investigating the Use of Generative Adversarial Networks-Based Deep Learning for Reducing Motion Artifacts in Cardiac Magnetic Resonance by Ma ZP, Zhu YM, Zhang XD, Zhao YX, Zheng W, Yuan SR, Li GY, Zhang TL

“…Image quality pre- and post-optimization was assessed using metrics including Peak Signal-to-Noise Ratio (PSNR), Structural Similarity Index (SSIM), Leningrad Focus Measure, and a 5-point Likert scale.Results: After GAN optimization, notable improvements were observed in the PSNR, SSIM, and focus measure metrics for the 100 images with simulated artifacts. …”
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Simultaneous Debridement and Titanium Mesh Reconstruction in Patients with Compound Depressed Skull Fracture: A Retrospective Descriptive Study by Srikant Das, Acharya Suryakant Pattajoshi, Mahesh Kumar Kusta, Dibakar Sarkar

“…A very low incidence of complications was observed in patients during their hospital stay and three-month follow-up. …”
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The Global Burden of Polycystic Ovary Syndrome in Women of Reproductive Age: Findings from the GBD 2019 Study by Jiang B

“…The highest incidence rates were observed in the High-income Asia Pacific region, particularly in Japan and New Zealand, while the lowest rates were in Central Europe. …”
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An animal model of severe acute respiratory distress syndrome for translational research by Kuo-An Chu, Chia-Yu Lai, Yu-Hui Chen, Fu-Hsien Kuo, I.-Yuan Chen, You-Cheng Jiang, Ya-Ling Liu, Tsui-Ling Ko, Yu-Show Fu

“…The physiological symptoms observed in this severe ARDS animal model are entirely consistent with the characteristics of clinical ARDS. …”
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Effects of Walnut Protein Peptides on Promotion of White Adipose Tissue Browning and Prevention of Obesity by Yankun FU, Yuzheng CAI, Zhiqiang FENG, Siru CHEN, Tianlin WANG, Lianjun SONG, Tiange LI

“…The morphological changes of inguinal WAT were observed, and the protein expression of key factors involved in WAT browning were detected. …”
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Serum Soluble Interleukin-2 Receptor Does Not Differentiate Complex Regional Pain Syndrome from Other Pain Conditions in a Tertiary Referral Setting by K. D. Bharwani, M. Dirckx, D. L. Stronks, W. A. Dik, F. J. P. M. Huygen

“…A statistically significant negative correlation was observed between sIL-2R levels and the CRPS severity score (rs=−0.468, p=0.024). …”
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Management Control System and Financial Performance of Micro Finance Institutions in Central Region Uganda by Arthur, Sunday, Caleb, Tamwesigire, Caroline Masiko, Murezi, George Stanley, Kinyata, Godfrey, Barigye, Keneth, Nuwagira, Moses, Agaba

“…The study confirmed efficient control system factor structure of observed variables and the latent variables. As a result, the study provided models for efficient Management control systems. …”
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Latissimus dorsi transfer or lower trapezius transfer: a treatment algorithm for irreparable posterosuperior rotator cuff tears muscles transfers in posterosuperior rotator cuff te... by Michael Kimmeyer, MD, Tilman Hees, MD, Laurens Allaart, MD, Rémi Nerot, MD, Arno Macken, MD, Geert-Alexander Buijze, MD, PhD, FEBHS, Laurent Lafosse, MD, Thibault Lafosse, MD

“…Materials and methods: This is a retrospective, single-center observational study. Included were patients who underwent arthroscopically assisted LDT (aaLDT) or arthroscopically assisted LTT (aaLTT) for PSIRCT. …”
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25 years of providing evidence on road safety interventions at the city level by Katherine Pérez, Katherine Pérez, Katherine Pérez, Elena Santamariña-Rubio, Maria José López, Maria José López, Maria José López, Maria José López, Lucia Artazcoz, Lucia Artazcoz, Lucia Artazcoz, Lucia Artazcoz, Josep Ferrando, Carlos Pastor, Adnan A. Hyder, Carme Borrell, Carme Borrell, Carme Borrell

“…Next, the paper quantifies the overall impact of road safety interventions by estimating the difference between the observed number of road traffic injuries and the expected number if no interventions had been implemented from January 2008 to December 2023, stratified by gender, injury severity, and mode of transport. …”
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