Eugenol inhibits NEAT1 as a ceRNA in pre-cancerous breast lesions by Yusheng Liu, Guijuan Zhang, Yi Ma, Min Ma, Xuefeng Jiang

“…Results: There were altogether 1162 mRNAs, 81 miRNAs, and 26 lncRNAs recognized as trend genes in breast cancer (BC) and pre-cancerous BC (pBC), constructing the ceRNA network using 3 lncRNAs, 3 miRNAs, and 38 mRNAs. It was observed that NEAT1, miR-383-5p, miR-9-5p, VEGF-A, and MMP-9 were downregulated in breast tumor cells in accordance with bioinformatics analysis. …”
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Interactive effect of dietary metabolizable energy levels with amino acid density in male broiler chickens: Carcass yield, nutrient intake, digestibility and excretion by Mehdi Toghyani, Shemil MacElline, Peter H. Selle, Sonia Y. Liu

“…No interactions were observed between ME and AA densities on carcass characteristics, nutrient digestibility, and excretion (P > 0.05). …”
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Neuroprotection by chronic administration of Fluoroethylnormemantine (FENM) in mouse models of Alzheimer's disease by Allison Carles, Aline Freyssin, Sarra Guehairia, Thomas Reguero, Michel Vignes, Hélène Hirbec, Gilles Rubinstenn, Tangui Maurice

“…Similar effects were observed with the daily FENM or MEM treatments. Animals infused with 0.1 mg/kg/day FENM showed prevention of Aβ25–35-induced neuroinflammation, oxidative stress and apoptosis. …”
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Immune responses of cattle vaccinated by various routes with Mycobacterium bovis Bacillus Calmette-Guérin (BCG) by Mitchell V. Palmer, Soyoun Hwang, Carly Kanipe, Ellie J. Putz, Luis Guilherme Virgilio Fernandes, Anna Didkowska, Paola M. Boggiatto

“…Similar to oral lyophilized BCG vaccinated animals, we did not observe any significant increases in the frequency of CD8 and γδ T cell proliferative and IFN-γ responses following SQ or oral liquid vaccinated animals. …”
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Heart Rate in Hypertension: Review and Expert Opinion by Jamshed Dalal, Arup Dasbiswas, Immaneni Sathyamurthy, Srinivasa Rao Maddury, Prafulla Kerkar, Sandeep Bansal, Joy Thomas, Sankar Chandra Mandal, Soura Mookerjee, Sivakadaksham Natarajan, Viveka Kumar, Nishith Chandra, Aziz Khan, R. Vijayakumar, J. P. S. Sawhney

“…A linear association between the two is observed especially in individuals with HR >80 bpm. …”
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Association between the C-reactive protein-triglyceride–glucose index and endometriosis: a cross-sectional study using data from the national health and nutrition examination surve... by Yanan Ren, Ren Xu, Junqin Zhang, Ying Jin, Di Zhang, Yazhuo Wang, Luyang Su

“…In addition, greater EM prevalence was observed with CTI in those > 40 years of age (OR 1.57 [95% CI 1.16–2.13]), body mass index ≥ 25 kg/m2 (OR 1.38 [95% CI 1.06–1.80]), smoking ≥ 100 cigarettes (OR 1.43 [95% CI 1.06–1.96]), married or living with partner (OR 1.41 [95% CI 1.09–1.85]), and oral contraceptive use (OR 1.35 [95% CI 1.07–1.69]). …”
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Evaluation of Health Science Students’ Knowledge, Attitudes, and Practices Toward Artificial Intelligence in Northern Saudi Arabia: Implications for Curriculum Refinement and... by ALruwail BF, Alshalan AM, Thirunavukkarasu A, Alibrahim A, Alenezi AM, Aldhuwayhi TZA

“…Additionally, multivariate analysis was employed to identify associated factors.Results: The present study demonstrated low knowledge, attitude, and practices among 55.7%, 37.0%, and 50.3% of health science students. We observed a positive correlation between knowledge and attitude (rho = 0.451, p = 0.001), knowledge and practice (rho = 0.353, p = 0.001), and attitude and practice (rho = 0.651, p = 0.001). …”
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Short-acting beta agonist, antibiotics, oral corticosteroid and association with mortality and cardiopulmonary events in patients with COPD: a retrospective cohort study in Alberta... by Mohit Bhutani, Irvin Mayers, Arsh Randhawa, Manisha Talukdar, Suzanne McMullen, Phongsack Manivong, Aaron Gelfand

“…Associations were modelled between mortality and SABA, antibiotic and OCS history, and between major adverse cardiac events (MACE) and cardiovascular disease (CVD) death and SABA history.Results Among 188 969 patients, dose–response effects were observed. Adjusting for covariates, rates were higher for patients with 6+ (vs 1) SABA dispenses (all-cause mortality HR: 1.20, 95% CI 1.16 to 1.24, p<0.001; COPD-related mortality HR: 1.40, 95% CI 1.34 to 1.46, p<0.001). …”
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Terlipressin at esophageal varicose bleeding at liver cirrhosis with portal hypertension syndrome by B. N. Kotiv, I. I. Dzidzava, D. P. Kashkin, A. V. Smorodsky, A. V. Slobodyanik, S. A. Soldatov, M. V. Koldin

“…Terlipressin injection was accompanied by significant decrease both linear, and volume velocity of portal blood flow on average by 41,6±9,7% (р=0,038) and 33,9±5,8% (р=0,024), respectively. This effect was observed for over 60 mines from the moment of injection. …”
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Are noise and air pollution related to the incidence of dementia? A cohort study in London, England by Derek G Cook, Frank J Kelly, Iain M Carey, H Ross Anderson, David P Strachan, Richard W Atkinson, Sean D Beevers, David Dajnak, John Gulliver

“…Increases in dementia risk were also observed with PM2.5, PM2.5 specifically from primary traffic sources only and Lnight, but only NO2 and PM2.5 remained statistically significant in multipollutant models. …”
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Evaluating the Effectiveness, Safety, and Satisfaction Rates of Phenol 90%, Trichloroacetic Acid 100%, and Radiofrequency in Lateral Matricectomy for the Treatment of Ingrown Toena... by Mohammadreza Ghassemi, Zahra Keshavarz, Elham Behrangi, Afsaneh Sadeghzadeh Bazargan, Alireza Jafarzadeh, Azadeh Goodarzi

“…Results Mean pre‐ and postoperative (second day) pain scores were 6.0 ± 3.3 and 0.75 ± 0.67 for Group 1, 6.25 ± 4.92 and 1.75 ± 0.58 for Group 2, and 6.25 ± 2.25 and 3.50 ± 0.50 for Group 3, with significant differences observed. RF treatment showed higher moderate postoperative pain compared to mild pain in the phenol and TCA groups. …”
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Integrating WHO thinking healthy programme for maternal mental health into routine antenatal care in China: a randomized-controlled pilot trial by Anum Nisar, Juan Yin, Jingjun Zhang, Wenli Qi, Jie Yu, Jiaying Li, Xiaomei Li, Atif Rahman

“…Although the study was not designed to detect differences between the intervention and control groups, we observed positive trends towards reductions in anxiety and depressive symptoms favoring the intervention arm. …”
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Size distribution of extracellular vesicles in pretreatment ascites and plasma is correlated with primary treatment outcome in advanced high-grade serous carcinoma by Maruša Herzog, Ivan Verdenik, Borut Kobal, Katarina Černe

“…A significant correlation between the D10 value of EVs in plasma and the chemotherapy response score (CRS) after NACT was observed. A smaller D10 value of plasma EVs was correlated with a better chemotherapy response. …”
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Acquisition of innate B cell properties and generation of autoreactive IgA antibodies by follicular B cells during homeostatic proliferation by Laura Kampe, Laura Kampe, Christian Melcher, Christian Melcher, Katrin Westphal, Katrin Westphal, Korbinian Brand, Niko Föger, Niko Föger, Kyeong-Hee Lee, Kyeong-Hee Lee

“…In light of the poor reactivity of FoBs to innate stimulation in vitro, the observed high expansion capacity of FoBs, their sustained repopulation of lymphoid and intestinal organs and their particularly prominent ability to induce class-switched auto-/polyreactive IgA antibodies in this antigen- and T cell-independent system was rather unexpected. …”
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Induction by caterpillars of stored and emitted volatiles in terpene chemotypes from populations of wild cotton (Gossypium hirsutum) by Marine Mamin, Mary V. Clancy, Galien Flückiger, Teresa Quijano-Medina, Biiniza Pérez-Niño, Luis Abdala-Roberts, Ted C. J. Turlings, Carlos Bustos-Segura

“…Intraspecific variation was also observed in the induced emissions of nitriles and certain terpenes. …”
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Interleukin-1 Gene Variability and Plasma Levels in Czech Patients with Chronic Periodontitis and Diabetes Mellitus by Petra Borilova Linhartova, Hana Poskerova, Marie Tomandlova, Jirina Bartova, Katerina Kankova, Antonin Fassmann, Lydie Izakovicova Holla

“…Although no significant associations were found in the genotype and allele frequencies of IL-1A (−889C/T), significant differences in the allele frequencies of IL-1B (+3953C/T) were observed between controls and CP patients (P<0.05). …”
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Investigating the implementation of infection prevention and control practices in neonatal care across country income levels: a systematic review by Emanuela Nyantakyi, Julia Baenziger, Laura Caci, Kathrin Blum, Aline Wolfensberger, Angela Dramowski, Bianca Albers, Marta Castro, Marie-Therese Schultes, Lauren Clack

“…However, further research is needed to understand the underlying relationships of factors and dynamics contributing to the observed practice variances in LMICs and HICs. Registration PROSPERO (CRD42022380379).…”
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Is Thermal Pulsation Therapy Effective for Dry Eyes Before and After Cataract Surgery? A Systematic Review and Meta-Analysis by Chen KY, Chan HC, Chan CM

“…The meta-analysis revealed a moderate effect of TPT, with a small but clinically significant improvement observed in MGYLS scores (Cohen’s d = 0.29, p = 0.033) and TBUT (Cohen’s d = 0.15, p = 0.029). …”
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Maternal smoking during infancy increases the risk of allergic diseases in children: a nationwide longitudinal survey in Japan by Kenji Shigehara, Naomi Matsumoto, Mitsuru Tsuge, Kazuhiro Uda, Yukie Saito, Masato Yashiro, Takashi Yorifuji, Masanori Ikeda, Hirokazu Tsukahara

“…In particular, a serious decline in the age of onset of allergic rhinitis has been observed. Passive smoking from parental smoking has a significant impact on children’s health; however, it is difficult to restrict smoking in the home. …”
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Does an increase in physiological indexes predict better cognitive performance: the PhyCog randomised cross-over protocol in type 2 diabetes by Frederic Dutheil, Guillaume T Vallet, Igor Tauveron, Julien S Baker, Valentin Magnon, Jordan Mille, Valentin Brusseau, Laetitia Silvert, Marie Izaute

“…All participants will be observed for 3 months following the intervention. The study will include a total of 81 patients with T2D.Cognitive performance and physiological variables will be assessed at baseline (week 0—W0), during the washout (W5, 72–96 hours after week 4), at the end of the intervention (W10), and at the end of the follow-up (W22). …”
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