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  1. 38981

    Artificial Intelligence–Related Dental Research: Bibliometric and Altmetric Analysis by Wei Lu, Xueqian Yu, Yueyang Li, Yi Cao, Yanning Chen, Fang Hua

    Published 2025-02-01
    “…Altmetric Attention Score was correlated with News Mentions (P < .001), and significant associations were observed amongst Dimension Citations, Mendeley Readers, and Web of Science Citations (P < .001). …”
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  2. 38982

    Burden of NASH related liver cancer from 1990 to 2021 at the global, regional, and national levels by Shuang Li, Shuang Li, Shuangjiang Li, Linjing Guan, Mingjuan Li, Jiahui Zhao, Min Wu, Qiuyun Li, Hui Li, Guoqing Ouyang, Guangdong Pan, Guangdong Pan

    Published 2025-01-01
    “…Similar patterns were observed for NRLC-related deaths and DALYs. Regionally, ASRs initially declined but then increased as SDI rose. …”
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  3. 38983

    Spatial transcriptomics reveals unique metabolic profile and key oncogenic regulators of cervical squamous cell carcinoma by Limin Zhou, Jiejie Liu, Peipei Yao, Xing Liu, Fei Chen, Yu Chen, Li Zhou, Chao Shen, You Zhou, Xin Du, Junbo Hu

    Published 2024-12-01
    “…Cell-cell communication analysis showed that various cells in tumor microenvironment were influenced by the signalling molecule APP released by cancer cells and higher expression of APP was observed in hypermetabolic regions. Furthermore, our results revealed the correlation between APP and the transcription factor TRPS1. …”
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  4. 38984

    Precise Detection of Gene Mutations in Fine-Needle Aspiration Specimens of the Papillary Thyroid Microcarcinoma Using Next-Generation Sequencing by Feng-xia Yu, Min-xia Hu, Han-xue Zhao, Li-juan Niu, Xue-yu Rong, Wei-hua Li, Qiang Zhu, Jian-ming Ying, Ning Lyu

    Published 2019-01-01
    “…Results. BRAF mutation was observed in 59 (81.94%) of 72 specimens. This mutation detected in BRAF was p.V600E (c.1799T>A) in exon 15 of all 59 specimens. …”
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  5. 38985

    Donafenib combined with sintilimab for advanced hepatocellular carcinoma: a single arm phase II trial by Xiaoyang Hong, Yongjian Guo, Wenbo Shi, Kangshun Zhu, Licong Liang, Liteng Lin, Ye Chen, Jingwen Zhou, Jingjun Huang, Jiabai Huang, Yaozhu Wu, Wensou Huang, Mingyue Cai

    Published 2025-02-01
    “…Treatment-related adverse events (TRAEs) occurred in 28 patients (93.3%) and grade 3 TRAEs were observed in 9 patients (30.0%). Conclusions Don-Sin showed promising antitumor effects with an acceptable safety profile in patients with advanced stage HCC. …”
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  6. 38986

    Early Endoscopic Outcomes After Risankizumab Are Associated With Fewer Hospitalizations and Surgeries in Crohn’s Disease by Brian G. Feagan, Jean-Frederic Colombel, Remo Panaccione, Stefan Schreiber, Marc Ferrante, Koji Kamikozuru, Christopher Ma, Wan-Ju Lee, Jenny Griffith, Namita Joshi, Kristina Kligys, Jasmina Kalabic, Si Xuan, Marla Dubinsky

    Published 2025-01-01
    “…No CD-related surgeries were observed through 52 weeks of risankizumab maintenance among patients who achieved vs did not achieve endoscopic outcomes following induction (endoscopic response, 0 vs 3.2/100 person-years; endoscopic remission, 0 vs 2.6/100 person-years; ulcer-free endoscopy, 0 vs 2.4/100 person-years; all P = .025). …”
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  7. 38987

    Coatomer complex I is required for the transport of SARS-CoV-2 progeny virions from the endoplasmic reticulum-Golgi intermediate compartment by Ai Hirabayashi, Yukiko Muramoto, Toru Takenaga, Yugo Tsunoda, Mayumi Wakazaki, Mayuko Sato, Yoko Fujita-Fujiharu, Norimichi Nomura, Koji Yamauchi, Chiho Onishi, Masahiro Nakano, Kiminori Toyooka, Takeshi Noda

    Published 2025-01-01
    “…During the later stages of SARS-CoV-2 infection, we observed a notable alteration in the distribution of COPI and ERGIC throughout the cytoplasm, suggesting their potential involvement in virus replication. …”
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  8. 38988
  9. 38989

    Thyroid Function in Korean Adolescents with Obesity: Results from the Korea National Health and Nutrition Examination Survey VI (2013–2015) by Won Kyoung Cho, Hyo-Kyoung Nam, Jae Hyun Kim, Young-Jun Rhie, Sochung Chung, Kee-Hyoung Lee, Byung-Kyu Suh

    Published 2018-01-01
    “…Positive linear associations were observed between TSH and BMI z-score (P=0.031), waist circumference (P=0.013), waist-height ratio (P=0.002), systolic blood pressure (P=0.001), total cholesterol (P=0.008), and triglyceride (P=0.002) after adjusting for age and sex. …”
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  10. 38990

    Phytochemical Profiling, GC-MS Analysis and Antibacterial Activity of Sida acuta leave Extracts Against Helicobacter pylori by Kamoldeen Ajijolakewu, Ayobami Elias Ajadi, S A Ayoola, Sheriffdeen Issa Bale, Taiwo Ayodeji Sorunke, Saheed Abayomi Onifade, Tomisin Oyawoye

    Published 2024-12-01
    “…Bactericidal effects were observed with the ethanol and aqueous extracts at 250 mg/mL and 500 mg/mL, respectively, while hexane showed no bactericidal activity at tested concentrations.  …”
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  11. 38991

    High Data-Rate Hilbert-Curved-Shaped MIMO Antenna With Improved Bandwidth and Circular Polarization for Wireless Capsule Endoscopy by Syed Misbah Un Noor, Syed Ahson Ali Shah, Shahid Khan, Izaz Ali Shah, Jamal Nasir, Salahuddin Khan, Slawomir Koziel

    Published 2025-01-01
    “…A good match between the measured and simulated results has been observed. At both ports, the axial ratio (&#x003C;3 dB) covers part of the ISM band in the homogeneous stomach, small intestine, and large intestine phantoms. …”
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  12. 38992

    Can oral caffeine decrease postoperative opioid consumption following posterior spinal fusion in adolescent idiopathic scoliosis? A randomized placebo-controlled trial by Anne Stuedemann, MSN, RN, CPNP, Richard M Schwend, MD FAAP FAOA, Kenneth A. Shaw, MD, Nicolette Saddler, MSN, APRN, FNP-C, Michon Huston, PA-C, Michael Benvenuti, MD, Julia Leamon, MSN, RN, CPN, Ashley K. Sherman, MA, John Anderson, MD

    Published 2025-03-01
    “…This trial's reported mean total oral opioid consumption range of 0.83 to 0.92 MME/kg is lower than the amounts typically observed in clinical trials. This finding could indicate a successful strategy in reducing opioid use, which aligns with current medical efforts for opioid stewardship.…”
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  13. 38993

    Triglyceride-independent associations between circulating levels of apolipoprotein C-III and biomarkers of inflammation by Dídac Llop, Pere Rehues, Silvia Paredes, Montse Guardiola, Josefa Girona, Roser Rosales, Yaiza Esteban, Lluís Masana, Daiana Ibarretxe, Joan-Carles Vallvé, Josep Ribalta

    Published 2025-01-01
    “…Our results suggest that apoCIII is associated with the low-grade inflammatory profile represented by glycoproteins, independent of triglyceride levels. Additionally, we observed a negative association with hsCRP, which, while seemingly paradoxical, has been reported in previous studies.…”
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  14. 38994

    Risk factors affecting polygenic score performance across diverse cohorts by Daniel Hui, Scott Dudek, Krzysztof Kiryluk, Theresa L Walunas, Iftikhar J Kullo, Wei-Qi Wei, Hemant Tiwari, Josh F Peterson, Wendy K Chung, Brittney H Davis, Atlas Khan, Leah C Kottyan, Nita A Limdi, Qiping Feng, Megan J Puckelwartz, Chunhua Weng, Johanna L Smith, Elizabeth W Karlson, Regeneron Genetics Center, Penn Medicine BioBank, Gail P Jarvik, Marylyn D Ritchie

    Published 2025-01-01
    “…Twenty-eight covariates had significant PGSBMI–covariate interaction effects, modifying PGSBMI effects by nearly 20% per standard deviation change. We observed overlap between covariates that had significant R2 differences among strata and interaction effects – across all covariates, their main effects on BMI were correlated with their maximum R2 differences and interaction effects (0.56 and 0.58, respectively), suggesting high-PGSBMI individuals have highest R2 and increase in PGS effect. …”
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  15. 38995

    Effects of the in ovo injection of an Escherichia coli vaccine on the hatchability and subsequent early post hatch characteristics of commercial layer chicks by K.E.C. Elliott, L.L. Lindsey, J.D. Evans, S.A. Leigh, K.J. Robinson, S.A. Fatemi, A. Mousstaaid, P.D. Gerard, J. L Purswell, E.D. Peebles

    Published 2025-01-01
    “…Cumulative mortality from 0 to 21 d of growout was 5.41% in the full dose treatment, whereas no mortalities were observed in the other treatment groups. While layer chicken embryos were able to survive to 3 wk post hatch after having received the PECV by in ovo injection, the full dose of the vaccine increased cumulative chick mortality and decreased chick BW through 3 wk post hatch.…”
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  16. 38996

    Sepsis in Internal Medicine: blood culture-based subtypes, hospital outcomes, and predictive biomarkers by Gaetano Zizzo, Gabriele Guazzardi, Daniela Bompane, Francesco Di Terlizzi, Giorgio Rotola, Ilario Stefani, Michela Medugno, Mario Bucalo, Antonino Mazzone

    Published 2025-01-01
    “…Median length of stay (LOS) was 14 days, and mean ward-to-intensive care unit (ICU) transfer and in-hospital mortality rates were 11 and 26%, respectively; significant differences were observed over the years, with LOS peaks preceding mortality peaks by 1 year. …”
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  17. 38997

    Concentration-dependent effects of immunomodulatory cocktails on the generation of leukemia-derived dendritic cells, DCleu mediated T-cell activation and on-target/off-tumor toxici... by Hazal Aslan Rejeski, Hazal Aslan Rejeski, Anne Hartz, Anne Hartz, Elias Rackl, Elias Rackl, Lin Li, Lin Li, Christoph Schwepcke, Christoph Schwepcke, Kai Rejeski, Kai Rejeski, Christoph Schmid, Christoph Schmid, Andreas Rank, Andreas Rank, Jörg Schmohl, Doris Kraemer, Peter Bojko, Helga Maria Schmetzer, Helga Maria Schmetzer

    Published 2025-01-01
    “…For Kit-M, we noted optimal generation of DC-subsets at intermediary concentration ranges of PGE1 (0.25-4.0 µg/mL), which facilitated upregulation of activated and memory T-cells upon mixed lymphocyte culture, and efficient anti-leukemic activity in cytotoxicity assays. For Kit-I, we observed DC/DCleu generation and enhanced T- and immune cell activation across a broader range of OK-432 concentrations (5-40 µg/mL), which also facilitated improved leukemic blast killing. …”
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  18. 38998

    Time Zero for Net Zero: A Coal Mine Baseline for Decarbonising Heat by Alison A. Monaghan, Luke Bateson, Adrian J. Boyce, Neil M. Burnside, Rebecca Chambers, Julia R. de Rezende, Eilidh Dunnet, Paul A. Everett, Stuart M. V. Gilfillan, Muhammad S. Jibrin, Gareth Johnson, Richard Luckett, Donald John MacAllister, Alan M. MacDonald, John W. Moreau, Laura Newsome, Alessandro Novellino, Barbara Palumbo-Roe, Ryan Pereira, Douglas Smith, Mike J. Spence, Vanessa Starcher, Helen Taylor-Curran, Christopher H. Vane, Thomas Wagner, David B. Walls

    Published 2022-12-01
    “…Integration of the wide array of time zero observations and understanding of coupled subsurface processes has significant potential to inform development of efficient and resilient geothermal infrastructure and to inform the design of fit-for-purpose monitoring approaches in the quest towards meeting Net Zero targets.…”
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  19. 38999
  20. 39000

    Late-stage diversification strategy for the synthesis of peptide acids and amides using hydrazides by Shoko Tanaka, Mizuki Kanno, Yosuke Tashiro, Tetsuo Narumi, Nobuyuki Mase, Kohei Sato

    Published 2023-10-01
    “…The amides of the resulting peptide showed more potent activity against E. coli than the acid form, and the most potent activity was observed from the hydrazide. Conclusions: The developed protocols allow hydrazides to be converted to acids or amides, enabling late-stage diversification of peptide C-terminal residues.…”
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