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38981
Artificial Intelligence–Related Dental Research: Bibliometric and Altmetric Analysis
Published 2025-02-01“…Altmetric Attention Score was correlated with News Mentions (P < .001), and significant associations were observed amongst Dimension Citations, Mendeley Readers, and Web of Science Citations (P < .001). …”
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38982
Burden of NASH related liver cancer from 1990 to 2021 at the global, regional, and national levels
Published 2025-01-01“…Similar patterns were observed for NRLC-related deaths and DALYs. Regionally, ASRs initially declined but then increased as SDI rose. …”
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38983
Spatial transcriptomics reveals unique metabolic profile and key oncogenic regulators of cervical squamous cell carcinoma
Published 2024-12-01“…Cell-cell communication analysis showed that various cells in tumor microenvironment were influenced by the signalling molecule APP released by cancer cells and higher expression of APP was observed in hypermetabolic regions. Furthermore, our results revealed the correlation between APP and the transcription factor TRPS1. …”
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38984
Precise Detection of Gene Mutations in Fine-Needle Aspiration Specimens of the Papillary Thyroid Microcarcinoma Using Next-Generation Sequencing
Published 2019-01-01“…Results. BRAF mutation was observed in 59 (81.94%) of 72 specimens. This mutation detected in BRAF was p.V600E (c.1799T>A) in exon 15 of all 59 specimens. …”
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38985
Donafenib combined with sintilimab for advanced hepatocellular carcinoma: a single arm phase II trial
Published 2025-02-01“…Treatment-related adverse events (TRAEs) occurred in 28 patients (93.3%) and grade 3 TRAEs were observed in 9 patients (30.0%). Conclusions Don-Sin showed promising antitumor effects with an acceptable safety profile in patients with advanced stage HCC. …”
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38986
Early Endoscopic Outcomes After Risankizumab Are Associated With Fewer Hospitalizations and Surgeries in Crohn’s Disease
Published 2025-01-01“…No CD-related surgeries were observed through 52 weeks of risankizumab maintenance among patients who achieved vs did not achieve endoscopic outcomes following induction (endoscopic response, 0 vs 3.2/100 person-years; endoscopic remission, 0 vs 2.6/100 person-years; ulcer-free endoscopy, 0 vs 2.4/100 person-years; all P = .025). …”
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38987
Coatomer complex I is required for the transport of SARS-CoV-2 progeny virions from the endoplasmic reticulum-Golgi intermediate compartment
Published 2025-01-01“…During the later stages of SARS-CoV-2 infection, we observed a notable alteration in the distribution of COPI and ERGIC throughout the cytoplasm, suggesting their potential involvement in virus replication. …”
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38988
Adequate Reporting Among Ventral Hernia Repair Operative Reports: A Cross-Sectional Study of Prevalence of Details and Association With Clinical Outcomes
Published 2024-06-01“…This is a retrospective cross-sectional observational study. Operative reports describing VHR were obtained from a medical-legal database. …”
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38989
Thyroid Function in Korean Adolescents with Obesity: Results from the Korea National Health and Nutrition Examination Survey VI (2013–2015)
Published 2018-01-01“…Positive linear associations were observed between TSH and BMI z-score (P=0.031), waist circumference (P=0.013), waist-height ratio (P=0.002), systolic blood pressure (P=0.001), total cholesterol (P=0.008), and triglyceride (P=0.002) after adjusting for age and sex. …”
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38990
Phytochemical Profiling, GC-MS Analysis and Antibacterial Activity of Sida acuta leave Extracts Against Helicobacter pylori
Published 2024-12-01“…Bactericidal effects were observed with the ethanol and aqueous extracts at 250 mg/mL and 500 mg/mL, respectively, while hexane showed no bactericidal activity at tested concentrations. …”
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38991
High Data-Rate Hilbert-Curved-Shaped MIMO Antenna With Improved Bandwidth and Circular Polarization for Wireless Capsule Endoscopy
Published 2025-01-01“…A good match between the measured and simulated results has been observed. At both ports, the axial ratio (<3 dB) covers part of the ISM band in the homogeneous stomach, small intestine, and large intestine phantoms. …”
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38992
Can oral caffeine decrease postoperative opioid consumption following posterior spinal fusion in adolescent idiopathic scoliosis? A randomized placebo-controlled trial
Published 2025-03-01“…This trial's reported mean total oral opioid consumption range of 0.83 to 0.92 MME/kg is lower than the amounts typically observed in clinical trials. This finding could indicate a successful strategy in reducing opioid use, which aligns with current medical efforts for opioid stewardship.…”
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38993
Triglyceride-independent associations between circulating levels of apolipoprotein C-III and biomarkers of inflammation
Published 2025-01-01“…Our results suggest that apoCIII is associated with the low-grade inflammatory profile represented by glycoproteins, independent of triglyceride levels. Additionally, we observed a negative association with hsCRP, which, while seemingly paradoxical, has been reported in previous studies.…”
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38994
Risk factors affecting polygenic score performance across diverse cohorts
Published 2025-01-01“…Twenty-eight covariates had significant PGSBMI–covariate interaction effects, modifying PGSBMI effects by nearly 20% per standard deviation change. We observed overlap between covariates that had significant R2 differences among strata and interaction effects – across all covariates, their main effects on BMI were correlated with their maximum R2 differences and interaction effects (0.56 and 0.58, respectively), suggesting high-PGSBMI individuals have highest R2 and increase in PGS effect. …”
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38995
Effects of the in ovo injection of an Escherichia coli vaccine on the hatchability and subsequent early post hatch characteristics of commercial layer chicks
Published 2025-01-01“…Cumulative mortality from 0 to 21 d of growout was 5.41% in the full dose treatment, whereas no mortalities were observed in the other treatment groups. While layer chicken embryos were able to survive to 3 wk post hatch after having received the PECV by in ovo injection, the full dose of the vaccine increased cumulative chick mortality and decreased chick BW through 3 wk post hatch.…”
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38996
Sepsis in Internal Medicine: blood culture-based subtypes, hospital outcomes, and predictive biomarkers
Published 2025-01-01“…Median length of stay (LOS) was 14 days, and mean ward-to-intensive care unit (ICU) transfer and in-hospital mortality rates were 11 and 26%, respectively; significant differences were observed over the years, with LOS peaks preceding mortality peaks by 1 year. …”
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38997
Concentration-dependent effects of immunomodulatory cocktails on the generation of leukemia-derived dendritic cells, DCleu mediated T-cell activation and on-target/off-tumor toxici...
Published 2025-01-01“…For Kit-M, we noted optimal generation of DC-subsets at intermediary concentration ranges of PGE1 (0.25-4.0 µg/mL), which facilitated upregulation of activated and memory T-cells upon mixed lymphocyte culture, and efficient anti-leukemic activity in cytotoxicity assays. For Kit-I, we observed DC/DCleu generation and enhanced T- and immune cell activation across a broader range of OK-432 concentrations (5-40 µg/mL), which also facilitated improved leukemic blast killing. …”
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38998
Time Zero for Net Zero: A Coal Mine Baseline for Decarbonising Heat
Published 2022-12-01“…Integration of the wide array of time zero observations and understanding of coupled subsurface processes has significant potential to inform development of efficient and resilient geothermal infrastructure and to inform the design of fit-for-purpose monitoring approaches in the quest towards meeting Net Zero targets.…”
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38999
Evaluation of the Sterile Insect Technique for the Control of the Melon Fly (<i>Bactrocera cucurbitae</i>) Under Laboratory and Semi-Field Conditions in Sri Lanka
Published 2024-12-01“…Significant differences were observed in percentage pupal survival, flight ability, and fertility rates (<i>p</i> < 0.05) at a 95% level of confidence. …”
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39000
Late-stage diversification strategy for the synthesis of peptide acids and amides using hydrazides
Published 2023-10-01“…The amides of the resulting peptide showed more potent activity against E. coli than the acid form, and the most potent activity was observed from the hydrazide. Conclusions: The developed protocols allow hydrazides to be converted to acids or amides, enabling late-stage diversification of peptide C-terminal residues.…”
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