Effects of chili straw on rumen fermentation, meat quality, amino acid and fatty acid contents, and rumen bacteria diversity in sheep by Jinlong Li, Jinlong Li, Jinlong Li, Yong Tuo, Yong Tuo, Yong Tuo, Linjiao He, Linjiao He, Linjiao He, Yan Ma, Yan Ma, Zhijun Zhang, Zhijun Zhang, Zhiqiang Cheng, Changjiang Zang, Tongjun Guo, Tongjun Guo

“…Key findings include: (1) No significant differences were observed in rumen pH, NH3-N, or acetic acid-to-propionic acid ratio across groups (P > 0.05). (2) Rumen microbial diversity indices did not vary significantly between groups (P > 0.05), though the relative abundance of Firmicutes and Proteobacteria increased, and Bacteroidota decreased in CS-fed groups, with specific genus-level changes. (3) Carcass weight decreased in the CS20% group (P < 0.01). (4) Cooking loss decreased in CS10%, 15%, and 20% groups (P < 0.05), and meat redness increased in CS15% and 20% groups (P < 0.01). (5) Saturated fatty acids decreased, while the PUFA/SFA ratio and amino acid profiles, including sulfur-containing amino acids (SAA), dibasic amino acids (DAA), essential amino acids (EAA), and total amino acids (TAA), increased with CS, with a significant rise in Gly content in the CS15% group (P < 0.05). …”
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Liver damage in patients living with HIV on antiretroviral treatment with normal baseline liver function and without HBV/HCV infection: an 11-year retrospective cohort study in Gua... by Jun Yu, Hao Liang, Fengxiang Qin, Junjun Jiang, Chunwei Qin, Yunxuan Huang, Bingyu Liang, Yuexiang Xu, Jiegang Huang, Zhiliang Xu, Chuanyi Ning, Yanyan Liao, Ning Zang, Jingzhen Lai, Wudi Wei, Li Ye, Xionglin Qin

“…The highest liver damage incidence was observed in patients with 6–12 months’ ART (15.16/100 person-years). …”
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Comparative evaluation of allograft particulate bone and cortical bone blocks combined with xenograft bone for labial bone defects in the aesthetic zone: a prospective cohort study by Li-Rong Huang, Yong-Jin Zhong, Xiao-Qing Zhang, Ze-Ru Feng, Yan-Cheng Lai, Hong-Kun Wu, An-Chun Mo

“…No complications were observed. Conclusion Both treatment approaches achieved satisfactory bone regeneration, but combining cortical bone blocks with granular grafts provided better outcomes for larger defects, with greater bone formation and less resorption. …”
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SNORA37/CMTR1/ELAVL1 feedback loop drives gastric cancer progression via facilitating CD44 alternative splicing by Banghe Bao, Minxiu Tian, Xiaojing Wang, Chunhui Yang, Jiaying Qu, Shunchen Zhou, Yang Cheng, Qiangsong Tong, Liduan Zheng

“…Alternative splicing and gene expression was observed by real-time quantitative RT-PCR and western blot assays. …”
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Prior Anticoagulation and Risk of Hemorrhagic Transformation in Acute Stroke: A Post Hoc Analysis of the PRODAST Study by Gerrit M. Grosse, Anika Hüsing, Andreas Stang, Nils Kuklik, Marcus Brinkmann, Martin Grond, Jens D. Rollnik, Lars Marquardt, Andrea Kraft, Eckhard Schlemm, Carsten Eggers, Christoph C. Eschenfelder, Christian Weimar, Hans‐Christoph Diener

“…Methods and Results This is a post hoc analysis of the prospective, multicenter, observational PRODAST (Prospective Record of the Use of Dabigatran in Patients With Acute Stroke or TIA) study, which was conducted in 86 stroke units in Germany between July 2015 and November 2020. …”
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Shatavari supplementation during eight weeks of resistance training increases training load, enhances skeletal muscle contractility and alters the skeletal muscle proteome in older... by Elsa Greed, Elsa Greed, Jack Pritchard, Lauren Struszczak, Esra Bozbaş, Georgia Ek, Jordan Acheson, Jordan Acheson, Ben Winney, Aaliyah Qadir, Karl Ka-Lam Wong, Joanna Bowtell, Mary O’Leary

“…Expression of proteins related to striated muscle contraction, transcription and translation were decreased by shatavari supplementation in older women.DiscussionThese novel observations support the notion that shatavari supplementation confers resistance to neuromuscular fatigue in older women. …”
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The near-optimal adjustment of carbon and nitrogen allocations into different organs in early-season rice cultivars with drastically different yield components under nitrogen appli... by Wen Ning, Wen Ning, Lin Su, Lin Su, Dandan Shi, Dandan Shi, Meina Ji, Meina Ji, Xiang Ouyang, Qingfeng Song, Caihong Shao, Xin-Guang Zhu, Shuoqi Chang, Shuoqi Chang

“…At maturity, the photosynthate labeled with 13C distribution ratio in the panicle was greater in the basipetal 2nd leaves than in the flag leaves for ZZ39, whereas the opposite was observed in LLY268. These different photosynthate allocation patterns and their responses to nitrogen application were linked with their corresponding tiller number and number of grains per panicle.DiscussionThis study shows that early-season rice has the ability to flexibly adapt their carbon and nitrogen allocation patterns to gain optimized yield components for higher yield under different nitrogen status. …”
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Soil preferential flow dynamics in the southern drylands of India—a watershed based approach by Pushpanjali, K. S. Reddy, Ashish S. Dhimate, K. Karthikeyan, Josily Samuel, A. G. K. Reddy, N. Ravi Kumar, K. V. Rao, Prabhat Kumar Pankaj, Jagriti Rohit, Manoranjan Kumar, V. K. Singh

“…Heterogeneous matrix flow and fingering were observed both at the surface and sub-surface, along with macropore flow with low and mixed interactions. …”
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J-shaped association between dietary thiamine intake and the risk of cognitive decline in cognitively healthy, older Chinese individuals by Yuanyuan Zhang, Xianhui Qin, Chengzhang Liu, Chun Zhou, Mengyi Liu, Panpan He, Ziliang Ye, Qiguo Meng, Yuanxiu Wei, Xinyue Su

“…A stronger positive association between thiamine intake and cognitive decline was observed in those with hypertension, obesity and those who were non-smokers (all p<0.05).Conclusions This study revealed a J-shaped association between dietary thiamine intake and cognitive decline in cognitively healthy, older Chinese individuals, with an inflection point at 0.68 mg/day and a minimal risk at 0.60–1.00 mg/day of dietary thiamine intake.…”
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Intracranial Aneurysms Treated with a Novel Coated Low-Profile Flow Diverter (p48 HPC)—A Single-Center Experience and an Illustrative Case Series by Nadja Krug, Jan S. Kirschke, Christian Maegerlein, Kornelia Kreiser, Maria Wostrack, Bernhard Meyer, Carolin Albrecht, Claus Zimmer, Tobias Boeckh-Behrens, Dominik Sepp

“…New braid deformation patterns were observed in 16.6% at the follow-up examination, but none with subsequent clinical significance. …”
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Risk of lung disease in the PI*SS genotype of alpha-1 antitrypsin: an EARCO research project by Teresa Martín, Catarina Guimarães, Cristina Esquinas, Maria Torres-Duran, Alice M. Turner, Hanan Tanash, Carlota Rodríguez-García, Angelo Corsico, José Luis López-Campos, Eva Bartošovská, Jens-Ulrik Stæhr Jensen, José María Hernández-Pérez, Maria Sucena, Marc Miravitlles

“…Conclusions We found that, as expected, the risk of lung disease associated with the PI*SS genotype is significantly lower compared with PI*ZZ, but does not differ from that observed in PI*SZ individuals, despite having higher serum AAT levels. …”
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The baked side: Cow's milk and egg protein threshold dose distributions in children reacting to baked milk and baked egg by Rocco Luigi Valluzzi, MD, Carla Riccardi, MD, Sara Urbani, MD, Davide Ursi, MD, Deborah Zavettieri, MD, Francesco Di Girolamo, PhD, Lamia Dahdah, MD, Veronica Calandrelli, PharmD, Vincenzo Fierro, MD, Alessandro Fiocchi, MD

“…Conclusions: Milk thresholds are similar to those already observed in baked allergic versus baked tolerant children, while EDs for egg are at least 1.6 times higher than those currently indicated.Egg-allergic patients could be exempt from the recommendations of absolute avoidance of foods when present in infinitesimal quantities, represented by precautionary allergen labelling based on current EDs.…”
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Comparative analysis of the performance, egg quality and ovarian immune function of fast and slow feather strains in tianfu green shell laying hens at various stages of egg product... by Zhi Hu, Hengyong Xu, Zhipeng Zhang, Yuxiang Lu, Yuxin Zhou, Jiajun Zhu, Qingqing Deng, Xi Wang, Yiping Liu, Yao Zhang, Yan Wang

“…Furthermore, EF hens exhibited the production of eggs with significantly thicker and stronger shells during the peak laying period (P < 0.05), while no notable differences were observed in other egg quality parameters. Immunologically, EF hens demonstrated elevated peak serum levels of IgA, IgG, and IgM compared to LF hens. …”
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Gibberellin-3 induced dormancy and suppression of flower bud formation in pitaya (Hylocereus polyrhizus) by Kamran Shah, Xiaoyue Zhu, Tiantian Zhang, Jiayi Chen, Jiaxuan Chen, Yonghua Qin

“…Transcriptomic analysis revealed batches of differentially expressed genes (DEGs) associated with phytohormone signal transduction, aligning with observed hormone changes. Notably, except four CONSTANS-like (CO) (HU06G02633, HU10G00019, HU04G00234, and HU02G01458), all other CO genes were preferentially active in GA3-treated buds. …”
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Integrated response of crop yields and greenhouse gas emissions to cropland management practices and natural factors: a global meta-analysis by Jiahui Dong, Shikun Sun, Guolong Zhan, Jingxin Sun, Yihe Tang, Yubao Wang

“…The study assessed the response of global crop yields and GHG to cropland management and natural factors (including mean annual temperature, mean annual rainfall, soil pH, soil C N ratio (SCN), soil organic matter, crop type, biochar (application rate Brate, biochar feedstock, C N ratio BCN, biochar pH BPH, biochar organic matter BTC), irrigation, N fertilizer (Nrate), tillage, straw management, plastic film mulch, duration of experiment, economic development, geographic location (state, country)) involving 167 papers from 17 crops in 27 countries, with a total of 1249 pairs of observations by using meta-analysis. The results showed that biochar application throughout the year improved crop yields, reduced GHG and was more suitable for use on C _4 crops. …”
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Cancer type-specific adverse events of immune checkpoint inhibitors: A systematic review and meta-analysis by Xuhui Tong, Rong Tang, Jin Xu, Wei Wang, Qiong Du, Si Shi, Xianjun Yu

“…Among individuals undergoing single-agent anti-PD-L1, higher frequency of all-grade pruritus occurred in 19.0 % of renal cell carcinoma (RCC) patients (95 % CI 15.2%–23.2 %), and the highest probability of developing other severe musculoskeletal disorders was observed in patients with RCC (6.2 %, 95 % CI 4.0%–9.0 %). …”
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A SPectroscopic Survey of Biased Halos in the Reionization Era (ASPIRE): Spectroscopically Complete Census of Obscured Cosmic Star Formation Rate Density at z = 4–6 by Fengwu Sun, Feige Wang, Jinyi Yang, Jaclyn B. Champagne, Roberto Decarli, Xiaohui Fan, Eduardo Bañados, Zheng Cai, Luis Colina, Eiichi Egami, Joseph F. Hennawi, Xiangyu Jin, Hyunsung D. Jun, Yana Khusanova, Mingyu Li, Zihao Li, Xiaojing Lin, Weizhe Liu, Romain A. Meyer, Maria A. Pudoka, George H. Rieke, Yue Shen, Wei Leong Tee, Bram Venemans, Fabian Walter, Yunjing Wu, Huanian Zhang, Siwei Zou

“…We also discuss the uncertainty of SFRD propagated from far-IR spectral energy distribution and IRLF at the bright end, which will need to be resolved with future ALMA and JWST observations.…”
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Unveiling the Potency of Gardenia Extract Against <i>H. pylori</i>: Insights from In Vitro and In Vivo Studies by Pornpen Werawatganone, Duangporn Werawatganon, Nattida Noonak, Maneerat Chayanupatkul, Tanittha Chatsuwan, Naruemon Klaikeaw, Walaisiri Muangsiri, Prasong Siriviriyakul

“…The inhibition zone was observed at the extract ≥ 1.97 mg/disk, and the extract presented anti-inflammatory potential. …”
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Association between ethylene oxide exposure and osteoarthritis risk: an analysis of NHANES data (2013–2014 and 2017–2018) by Zhongshan Li, Zhongshan Li, Qi Qu, Qi Qu, Zhiyu Wang, Zhiyu Wang, Shuanglin Mou, Rui Jiang, Rui Jiang, Wensheng Zhu, Wensheng Zhu

“…Additionally, a nonlinear U-shaped and J-shaped association was observed in the unadjusted and adjusted RCS models, respectively. …”
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Sepiolite immobilizes soil Cd to optimize microbial community structure thereby promoting wheat growth and reducing Cd accumulation by Ziqi Li, Xiaoxun Xu, Xin Qi, Changlian Xu, Guiyin Wang, Shirong Zhang, Zhanbiao Yang, Zhang Cheng, Junzhuo Cai, Guochun Lv, Ting Li, Yulin Pu, Yongxia Jia

“…The most substantial changes were observed when the sepiolite application rate reached 4500 kg ha−1. …”
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