Role of Prothrombin and Methylenetetrahydrofolate Reductase Gene Polymorphisms as well as Thrombophilia Markers, as Risk Factors for Unexplained Recurrent Miscarriage: A Case-Contr... by Zeinab Ahmed Abd Elhameed, Omar M Shaaban, Hanan G Abd Elazeem, Azza Abouelfadle, Tarek Farghaly, Ghada Mahran, Mohamed Ismail Seddik

“…PT G20210A showed two in group I were A/G, no A/G in group II, and no AA carrier in the either group. G allelewas observed in 99.5% of the group I and 100% of the group II, while A allele was detected in 0.5% of group I. …”
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Effectiveness of nurse-led care in patients with rheumatoid arthritis: a systematic review and meta-analysis by Dan Liu, Li Liu, Lin Yang, Ting Wen, Peng Xiang, Guifang Pi

“…In terms of self-efficacy, no significant difference was observed between NLC and usual care (SMD=0.56, 95% CI (−0.09, 1.21)) or between NLC and rheumatologist-led care (SMD=0.20, 95% CI (−0.19, 0.59). …”
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Genome-wide association study and genomic prediction of root system architecture traits in Sorghum (Sorghum bicolor (L.) Moench) at the seedling stage by Muluken Enyew, Mulatu Geleta, Kassahun Tesfaye, Amare Seyoum, Tileye Feyissa, Admas Alemu, Cecilia Hammenhag, Anders S. Carlsson

“…The genomic prediction accuracy estimated for the studied traits using five Bayesian models ranged from 0.30 to 0.63 while it ranged from 0.35 to 0.60 when the RR-BLUP model was used. The observed moderate to high prediction accuracy for each trait suggests that genomic selection could be a feasible approach to sorghum RSA-targeted selection and breeding. …”
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Effect of Different Anti-hypertensive Drugs on Circadian Blood Pressure Profile in Elderly Hypertensive Patients by Bingqing YU, Jinping ZHOU, Zhongxian FENG, Junxia XU

“…According to the survey of drug use, 204 elderly hypertension patients who were treated in cadre's wards of Fuzhou General Hospital were divided into five groups: 1) long-acting calcium channel blockers (CCB group)(<italic>n</italic>=50);2) angiotensin converting enzyme inhibitors (ACEIs) or angiotensinⅡreceptor blockers (ARBs)(AA group)(<italic>n</italic>=22);3) treated with joint anti-hypertensive scheme including ACEIs or ARBs (but not including diuretics)(AAND group)(<italic>n</italic>=60);4) treated with joint anti-hypertensive scheme including diuretics (but not including ACEIs or ARBs)(DNAA group)(<italic>n</italic>=19);5) treated with joint anti-hypertensive scheme including diuretics and ACEIs or ARBs group (DAA group)(<italic>n</italic>=53), to observe the profile on circadian blood pressure in each group, binary <italic>Logistic</italic> regression analysis was used to evaluate the correlation between circadian blood pressure profile and its influencing factors.Results:Compared to the CCB group, the level of all day average SBP and daytime SBP in the DAA group were both lower (all <italic>P</italic>&lt;0.01), the decreasing level of SBP at night in the DAA group was higher (<italic>P</italic>&lt;0.05). …”
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The Effect of A2E on the Uptake and Release of Calcium in the Lysosomes and Mitochondria of Human RPE Cells Exposed to Blue Light by Mao-Mei Luo, Lin Chen, Shu Wang, Chun Zeng, De-Zhi Li, YeGe Bi, Long-Qian Liu, Shan-Jun Cai

“…After A2E treatment, the fluorescence intensity of the calcium in the cytoplasm was further increased (P<0.05), while that in the mitochondria and lysosomes decreased (P<0.05). In addition, we observed that nifedipine reduced the fluorescence intensity of calcium in the RPE cells. …”
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Outcomes of Open Reduction and Modified McLaughlin’s Procedure in Neglected Posterior Shoulder Dislocation by Vikas, Jatin Prakash, Karan Maggo, Jujhar Singh, Ankesh Jain, Naval Bhatia

“…Strength and range of motion in the treated limbs were satisfactory, with good stability observed in all treated shoulders. Radiographic evaluation did not reveal anatomical misalignment or associated lesions. …”
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Efficacy of electroacupuncture for insomnia in cancer patients: a systematic review and meta-analysis by Xiaodong Liu, Ning Xu, Shangpei Wang, Qingjun Jia

“…No significant differences were observed in the Athens Insomnia Scale (AIS), sleep duration (SD), sleep efficiency (SE), or sleep quality (SQ) scores between the EA and control groups.ConclusionElectroacupuncture has shown promising potential in treating cancer-related insomnia by increasing total sleep time and reducing sleep disturbances. …”
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Decision support systems for waste-to-energy technologies: A systematic literature review of methods and future directions for sustainable implementation in Ghana by Theophilus Frimpong Adu, Lena Dzifa Mensah, Mizpah Ama Dziedzorm Rockson, Francis Kemausuor

“…The study utilized the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) approach in analyzing and synthesizing a diverse range of studies to identify key observations, trends, and a pathway for future research. …”
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The Usefulness of the Pressure Algometer in the Diagnosis and Treatment of Orofacial Pain Patients: A Systematic Review by Agata Kamińska, Bartosz Dalewski, Ewa Sobolewska

“…The titles and abstracts from electronic search results were screened for keywords and evaluated by two observers, with the following inclusion criteria: published since 1997, written in English, and encompassing human research. …”
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Patient-Generated Collections for Organizing Electronic Health Record Data to Elevate Personal Meaning, Improve Actionability, and Support Patient–Health Care Provider Communicatio... by Drashko Nakikj, David Kreda, Karan Luthria, Nils Gehlenborg

“…The app also allows patients to add text notes to collections and their constituent records. By observing how patients used features to select records and assemble them into collections, our goal was to learn about their preferred mechanisms to complete these tasks and the challenges they would face in the wild. …”
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Effects of Ginseng Peptides on Laxative in Mice by Qiannan WANG, Wen YANG, Tingfang XUE, Jiaqi ZOU, Tao FENG, Lei YU, Yunfeng BI, Lina WANG

“…After 7 consecutive days of intervention with GPs, the small intestine peristalsis and defecation time, as well as pathological changes in the small intestine villus tissue of each group of mice were observed and compared. The improvement effect of GPs on mouse constipation was evaluated by detecting the content of brain gut peptide indicators in the serum of each group of mice, including substance P (SP) and vasoactive intestinal peptide (VIP). …”
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Elevation of ganglioside degradation pathway drives GM2 and GM3 within amyloid plaques in a transgenic mouse model of Alzheimer's disease by Wenxuan Wang, Sarah J. Myers, Nikita Ollen-Bittle, Shawn N. Whitehead

“…Significantly greater levels of simple gangliosides GM2 and GM3 were observed in the cortex and dentate gyrus of the hippocampus in transgenic mice at 12 and 18 m than in age-matched controls. …”
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Abdominal visceral and subcutaneous adipose tissue and associations with cardiometabolic risk in Inuit, Africans and Europeans: a cross-sectional study by Gregers Stig Andersen, Mette Aadahl, Niels Grarup, Torsten Lauritzen, Bendix Carstensen, Pernille Falberg Rønn, Marit Eika Jørgensen, Dirk Lund Christensen

“…Generally weaker associations were observed for women. Furthermore, the absolute levels of several of the cardiometabolic outcomes differed between the ethnic groups.Conclusions VAT and SAT were associated with several of the cardiometabolic risk factors beyond overall adiposity. …”
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Explaining the Antecedents and Consequences of the Glass Cliff in Service Organizations by Sara Kavoosi, Ali Safari, Ali Shaemi Barzoki

“…Objective The concept of the "glass cliff" refers to the observed trend of appointing women to leadership roles in contexts that are inherently risky or crisis-prone. …”
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PATTERNS OF CLINICAL MEDICO-LEGAL CASES: A RETROSPECTIVE STUDY AT A distt headquarter hospital charsadda by Nayella Nijat Bangash, Naheed Siddiqui, Urooj Khushbakhat Khan, Ihsan Ullah, Faiza Nadeem, Farzand Iqbal

“…Poisoning cases were observed in 25 instances, constituting 5.00% of the total MLC. …”
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Development and Validation of a Photoplethysmography System for Noninvasive Monitoring of Hemoglobin Concentration by Hongyun Liu, Fulai Peng, Minlu Hu, Jinlong Shi, Guojing Wang, Haiming Ai, Weidong Wang

“…In ROC analysis, PLS and BP models were good at predicting Hb ≥ 12 g/dL with area under the curve of 0.828 and 0.824, respectively. Observed differences between invasive and noninvasive Hb measurements displayed no significant correlation with perfusion index values. …”
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Electroacupuncture Improves Clearance of Amyloid-β through the Glymphatic System in the SAMP8 Mouse Model of Alzheimer’s Disease by Pei-zhe Liang, Li Li, Ya-nan Zhang, Yan Shen, Li-li Zhang, Jie Zhou, Zhi-jie Wang, Shu Wang, Sha Yang

“…After EA treatment, Morris water maze (MWM) test was used to evaluate the cognitive function; HE and Nissl staining was performed to observe the brain histomorphology; ELISA, contrast-enhanced MRI, and immunofluorescence were applied to explore the mechanisms underlying EA effects from Aβ accumulation, glymphatic system function, reactivity of astrocytes, and AQP4 polarization, respectively. …”
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Association between the atherogenic index of plasma and non-alcoholic fatty liver disease in Korean pregnant women: secondary analysis of a prospective cohort study by Rong Shuai, Yuxing He, Dongqian Yang, Yingying Zhang, Li Zhang

“…The subjects included in the study had an average AIP of 0.22 (0.11, 0.37), and NAFLD occurred in 110 (18.8%) pregnant women. We observed a positive linear association between AIP and NAFLD (OR = 1.33, 95% CI: 1.19–1.48), which persisted after adjusting for potential confounders (OR = 1.2, 95% CI: 1.06–1.37). …”
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Integrated bioinformatics analysis identified cuproptosis-related hub gene Mpeg1 as potential biomarker in spinal cord injury by Dandan Mao, Qi Chen, Shuolan Tong, Zixia Xu, Guofeng Yu, Chuan Chang, Yao Lv

“…From these modules, we identified two hub genes, Cd48 and Mpeg1, which exhibited a strong positive correlation (R = 0.92) and shared similar pathways. Furthermore, we observed a positive correlation between M2 macrophages and Cd48/Mpeg1. …”
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Predictive Value of Initial 18F-FDG PET/CT for Identifying EGFR and KRAS Mutations in Patients with Non-small-cell Lung Cancer by Ozge Vural Topuz, Nur Buyukpinarbasili

“…Methods: This retrospective observational study examined patients with NSCLC who underwent 18F-FDG PET/CT for staging from August 2021 to January 2024. …”
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