Application of organoids in drug screening of gynecological malignant tumors by JIANG Yuanyuan, WEI Wenfei, WU Jingya, LI Huawen

“…However, the actual clinical effectiveness is often influenced by various factors, such as adverse reactions due to drug toxicity and the drug resistance and insensitivity observed in some patients, which limit improvements in patient survival rates. …”
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Risdiplam utilization, adherence, and associated health care costs for patients with spinal muscular atrophy: a United States retrospective claims database analysis by Anish Patel, Walter Toro, Min Yang, Wei Song, Raj Desai, Mingchen Ye, Nadia Tabatabaeepour, Omar Dabbous

“…Conclusions Nonadherence to risdiplam was observed in the first year of treatment, especially for patients with SMA type 4 and patients aged 6–12 years. …”
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Azithromycin in the Management of Upper Respiratory Tract Infections (URTIs): Indian Real-Life Experience by Dominic M, Srivastava R, Shah K, Naik SM, Rout K, Ray B, Patil D, Rana D, Swami OC

“…This study aims to evaluate the effectiveness and safety of Azithromycin in treatment of URTIs in a real-world setting.Methods: This multicenter, retrospective, observational study was conducted across 184 Ear, Nose, and Throat (ENT) clinics in India. …”
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Poor outcome despite modern treatments: A retrospective study of 99 patients with primary and secondary plasma cell leukemia by Camille Tessier, Richard LeBlanc, Jean Roy, Sabrina Trudel, Julie Côté, Marc Lalancette, Jean‐Samuel Boudreault, Émilie Lemieux‐Blanchard, Rayan Kaedbey, Michel Pavic

“…The median progression‐free survival (PFS) to frontline treatment and overall survival (OS) were, respectively, 4.8 (95% CI, 0.4–9.2) and 18.3 months (95% CI, 0.0–39.0) for pPCL and 0.8 (95% CI, 0.5–1.1) and 1.2 months (95% CI, 0.9–1.5) for sPCL (both p < 0.001). We observed no improvement in OS over time (2005–2012 vs. 2013–2020, p = 0.629 for pPCL and p = 0.329 for sPCL). …”
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The influence of locus of control, coping strategies and time perspective on post-traumatic growth in survivors with primary breast cancer by Alexandra-Cristina Paunescu, Marina Kvaskoff, Cyrille Delpierre, Lidia Delrieu, Guillemette Jacob, Myriam Pannard, Marie Préau

“…Further studies, especially longitudinal studies, are needed to confirm the observed associations between health behaviours, health locus of control, time perspective, and PTG scores. …”
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The validation and cross-cultural adaptation of the PainDETECT questionnaire in osteoarthritis-related pain by Xiaofeng Chang, Shuxin Yao, Jie Wei, Lei Shang, Chao Xu, Jianbing Ma

“…Results The PDQ-CV demonstrated good acceptability among KOA patients, with no floor or ceiling effects observed. Internal consistency was high (Cronbach’s α = 0.896), and test-retest reliability was excellent (ICC = 0.994; 95% CI: 0.943–1.045). …”
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Therapeutic Effect of Repetitive Transcranial Magnetic Stimulation Combined with Local Vibration Therapy on Children with Hemiplegic Cerebral Palsy by LI Mingdi, LIANG Guanjun, ZHANG Dali, ZHANG Hewei, WANG Wei, GU Qin

“…ObjectiveTo observe the effect of repetitive transcranial magnetic stimulation (rTMS) combined with local vibration (LVB) therapy on lower limb spasticity, balance function and gait function in children with hemiplegic cerebral palsy（HCP).MethodsA total of 66 children with HCP , who were treated in the Children's Hospital of Soochow University from January 2022 to December 2022 were randomly divided into control group, rTMS group and combined group, with 22 cases in each group. …”
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Water scarcity in semi-arid California compromises perennial alfalfa’s high yield and carbon sinking potentials by Tianxin Wang, Kanishka Mallick, Joseph Verfaille, Daphne Szutu, Dennis Baldocchi

“…However, a notable decline in NEE (-175 g C m−2 y−1) was observed in 2022, which coincided with reduction in GPP (-1794 g C m−2 y−1) and ET (722 mm y−1). …”
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Annealing temperature modify of crystalline structure, magnetic properties and antibacterial performance in nickel substituted cobalt ferrite nanoparticles utilizing natural-fine-s... by Laksmita Farah Bestari, Lathifah Iqlimatussholihah, Nurdiyantoro Putra Prasetya, Kusumandari, Utari, Riyatun, Budi Purnama

“…The VSM result showed that a narrow hysteresis curve was observed for the NiCFO-fs sample compared to NiCFO-pa. …”
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Inflammatory Monocyte Subsets Correlation with Iron Levels in Low Vitamin D Pediatric Transfusion-Dependent Thalassemia by Ghozali M, Matahari M, Cahyadi AI, Agustini SD, Ghrahani R, Reniarti L, Setiabudiawan B, Panigoro R

“…A correlational study was performed.Results: We did not find a correlation between low vitamin D levels (22.9 ng/mL ± 3.9) and monocyte characteristics, iron status, or hematology profile. However, we observed a negative correlation between the percentage of intermediate and non-classical monocytes and hemoglobin and ferritin levels (P = 0.02, r = − 0.3; P = 0.04, r = − 0.3). …”
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Characterization of polyethylene and polyurethane microplastics and their adsorption behavior on Cu2+ and Fe3+ in environmental matrices by Ilaria Zanoni, Lucia Briccolani, Lara Faccani, Magda Blosi, Simona Ortelli, Matteo Crosera, Giovanna Marussi, Stefania Albonetti, Anna Luisa Costa

“…Finally, we assessed the metal adsorption capacity to establish the role of microplastics in the transport of heavy metals in the environment. We observed selective adsorption for Cu2⁺ ions, which was both medium-dependent (more ions adsorbed in Elendt M7) and plastic-dependent, with PU showing a stronger affinity for Cu2⁺ in MilliQ and Egg water. …”
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Impact of Charge on Strange Compact Stars in Rastall Theory by Malick Sallah, Muhammad Sharif

“…These constants are determined using suitable matching conditions and observational data for compact objects which include Her X-1, SAX J 1808.4-3658, PSR J038-0842, LMC X-4 and SMC X-1. …”
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Scalable production of bio-calcium oxide via thermal decomposition of solid - hatchery waste in a laboratory-scale rotary kiln by Suwanan Chuakham, Ajchara I. Putkham, Yuwadee Chaiyachet, Arnusorn Saengprajak, Kriangsak Banlue, Nipon Tanpaiboonkul, Apipong Putkham

“…The effects of the calcination process in either an air or N2 atmosphere on the calcined product were also observed. Instrumental analysis shows that the production yield and purity of bio-CaO were in the range of 49–56 wt% and 97–98%, respectively. …”
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Alterations in Adipose Tissue and Adipokines in Heterozygous APE1/Ref-1 Deficient Mice by Eun-Ok Lee, Hao Jin, Sungmin Kim, Hee Kyoung Joo, Yu Ran Lee, Soo Yeon An, Shuyu Piao, Kwon Ho Lee, Byeong Hwa Jeon

“…Histological and immunohistochemical analyses were conducted to observe adipocyte size and macrophage infiltration of WAT. …”
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A five-finger mnemonic for teaching schoolchildren the theoretical components of adult basic life support: a modified reactive Delphi-guided development and memorability pilot test... by Nino Fijačko, Robert Greif, Špela Metličar, Gregor Štiglic, Benjamin S. Abella, Matej Strnad, the Delphi study investigators

“…Pre-training, no cards with 5-finger mnemonic content were arranged correctly, but post-training, progress improvement was observed, especially in older schoolchildren (Z = -2.727, p = 0.006). …”
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Efficacy and safety of single-branched stent graft in the treatment of type B aortic dissection: a meta-analysis of cohort studies by Wenxiao Lin, Fuyuan Cai, Jinliang Yan, Xiaolei Lin

“…However, no significant differences were observed between SBSG and other surgical methods in terms of technique success rate (OR = 1.51, 95%CI(0.55, 4.14), P = 0.42), hospital length of stay (OR = 1.51, 95%CI(0.55, 4.14), P = 0.42), aortic false lumen thrombosis rate (OR = 1.30, 95%CI(0.55, 3.07), P = 0.56), pulmonary infection rate (OR = 0.50, 95%CI(0.16, 1.58), P = 0.24), and 30-day postoperative mortality (OR = 0.41, 95%CI(0.12, 1.35), P = 0.41). …”
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Tropical Cyclone Size Prediction and Development of An Error Correction Method by Guo Ruichen, Xu Jing, Wang Yuqing

“…In 47% of samples, errors in the radius of maximum wind (RMW) could be more than twice as large as observations, while R33 and R26 are also overestimated. …”
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The role of long non-coding RNA LINC00839 in oral squamous cell carcinoma based on bioinformatics and experimental research by Ashkan Kalantary-Charvadeh, Saman Morovat, Somayeh Aslani, Nasrin Ziamajidi, Amirnader Emami Razavi, Roghayeh Abbasalipourkabir

“…A significant positive correlation was observed between LINC00839 and CCNE1 mRNA expression, along with a significant negative correlation between LINC00839 and miR-195-5p expression. …”
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Risk factors for mediastinal lymph node metastasis and lung metastasis in papillary thyroid carcinoma patients: who benefits from preoperative computed tomography? by Yoko Omi, Juro Yanagida, Yusaku Yoshida, Kiyomi Horiuchi, Takahiro Okamoto

“…MLNM and lung metastases were detected in 1.2% and 3.3% of patients, respectively. cT3-4, cN1, central LN metastasis, and lateral LN metastasis were RFs for MLNM in all patients (p &lt; 0.05, p &lt; 0.05, p &lt; 0.05, p &lt; 0.01) and older patients (age: ≥55 years) (p &lt; 0.01, p &lt; 0.05, p &lt; 0.05, p &lt; 0.05). cT3-4, cN1, gross extrathyroidal extension, central LN metastasis, and lateral LN metastasis were RFs for lung metastasis in all patients (p &lt; 0.01, p &lt; 0.05, p &lt; 0.01, p &lt; 0.01, p &lt; 0.01, respectively). cN1 and gross extrathyroidal extension, central LN metastasis, and lateral LN metastasis were RFs in older patients (p &lt; 0.01, p &lt; 0.01, p &lt; 0.05, p &lt; 0.01), while lateral LN metastasis was an RF for lung metastasis in those of &lt;55 years of age (younger patients) (p &lt; 0.05). No MLNM was observed in cT1-2cN0 PTC patients, who accounted for 50.5% of patients included in the MLNM analysis. …”
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A Cross-Sectional Comparative Study of the Performance of the Widal Test and the Typhidot Immunoassay for Typhoid Fever Diagnosis in the West Region of Cameroon by Karimo Ousenu, Innocent Mbulli Ali, Leonard Fonkeng Sama, Marcel Nsangou Ndam, Thibau Florant Tchouangueu, Christopher Bonglavnyuy Tume

“…Cohen’s kappa estimates were 0.1660 (0.121–0.211) and 0.386 (0.312–0.460) for the Widal test and Typhidot immunoassay for 53.6% and 76.16% agreements of all observations, respectively. Conclusion. The Widal test was found to have a lower predictive value for the diagnosis of typhoid fever in our setting. …”
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