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Narcolepsy: Pathophysiology and Neuropsychological Changes
Published 2003-01-01“…Findings on the role of the neuropeptide hypocretin are opening new avenues of research and new strategies for therapy. …”
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62
The role of the corticotropin-releasing hormone and its receptors in the regulation of stress response
Published 2021-04-01“…Stress is an essential part of everyday life. The neuropeptide corticotropin-releasing hormone (CRH, also called CRF and corticoliberin) plays a key role in the integration of neuroendocrine, autonomic and behavioral responses to stress. …”
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63
Food intake regulation during pregnancy and lactation in mice with reduced activity of the melanocortin system
Published 2016-05-01“…Hypothalamic melanortin receptor (MCR) activation inhibits appetite. Neuropeptide Y (NPY) and Agouti Related Protein (AgRP) are coexpressed in some hypothalamic neurons and stimulate feeding, NPY via inhibition of MCR-expressing neurons, and AgRP via MCR4 antagonism. …”
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64
Differentially localizing isoforms of the migraine component calcitonin gene-related peptide (CGRP), in the mouse trigeminal ganglion: βCGRP is translated but, unlike αCGRP, not so...
Published 2025-01-01“…Abstract Objective The neuropeptide calcitonin gene-related peptide (CGRP) has been established to be a key signaling molecule in migraine, but little is known about the differences between the two isoforms: αCGRP and βCGRP. …”
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65
Exploring the role of ubiquitination modifications in migraine headaches
Published 2025-01-01“…Calcitonin gene-related peptide (CGRP) plays a dominant role and activation of MAPK and NF-κB signaling pathways regulates neuropeptide release, glial cell activation, and amplification of nociceptive signals. …”
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66
A high-protein diet-responsive gut hormone regulates behavioral and metabolic optimization in Drosophila melanogaster
Published 2024-12-01“…Gut-derived CCHa1 is received by a small subset of enteric neurons that produce short neuropeptide F, thereby modulating protein-specific satiety. …”
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67
Cholecystokinin facilitates the formation of long-term heterosynaptic plasticity in the distal subiculum
Published 2025-02-01“…Cholecystokinin (CCK), is the most abundant neuropeptide in the central nervous system, which broadly regulates the animal’s physiological status at multiple levels, including neuroplasticity and its behavioral consequences. …”
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68
Pre-Emptive Treatment of Lidocaine Attenuates Neuropathic Pain and Reduces Pain-Related Biochemical Markers in the Rat Cuneate Nucleus in Median Nerve Chronic Constriction Injury M...
Published 2012-01-01“…This study investigates the effects of lidocaine pre-emptive treatment on neuropathic pain behavior, injury discharges of nerves, neuropeptide Y (NPY) and c-Fos expression in the cuneate nucleus (CN) after median nerve chronic constriction injury (CCI). …”
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69
Modulation by NPY/NPF-like receptor underlies experience-dependent, sexually dimorphic learning
Published 2025-01-01“…Transcriptomic and behavioral analysis revealed that the neuropeptide receptor npr-5, an ortholog of the mammalian NPY/NPF-like receptor, regulates male learning by modulating neuronal activity. …”
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70
Nutrient status alters developmental fates via a switch in mitochondrial homeodynamics
Published 2025-02-01“…Pre-NRC starvation reduces prothoracicotropic neuropeptide hormone signaling, insulin signaling, and TORC1 activity in PG cells, which prevent mitochondrial fragmentation and import of Disembodied, a key steroidogenic enzyme. …”
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71
Vertebral artery dissection in a patient with migraine treated with calcitonin gene-related peptide monoclonal antibody: a case report and FAERS database analysis
Published 2025-01-01“…Calcitonin gene-related peptide (CGRP) is a multifunctional neuropeptide with vasodilatory effects. The use of anti-CGRP monoclonal antibodies (CGRP mAb) may affect cerebrovascular disease risk; however, no reports have associated CGRP mAb with CeAD. …”
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72
Comparison of Plasma NPY and Zinc Levels of Elite Weightlifters and Sedentaries
Published 2021-08-01“…Neuropeptide Y (NPY), a strong stimulant of nutrition, and zinc, which has an important effect on nutrition regulation, have attracted the attention of many researchers. …”
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73
Pituitary adenylate cyclase-activating polypeptide plays a role in neuropsychiatric and substance use disorders: sex-specific perspective
Published 2025-02-01“…The neuropeptide pituitary adenylate cyclase-activating peptide (PACAP) plays a pivotal role in regulating stress, fear, and anxiety responses. …”
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74
Mettl3-m6A-NPY axis governing neuron–microglia interaction regulates sleep amount of mice
Published 2025-02-01“…We also showed that Mettl3 regulates neuropeptide Y (NPY) via m6A modification and Mettl3 conditional knockout (cKO) mice displayed significantly decreased expression of NPY in thalamus. …”
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75
The Alpha-Melanocyte Stimulating Hormone Induces Conversion of Effector T Cells into Treg Cells
Published 2011-01-01“…The neuropeptide alpha-melanocyte stimulating hormone (α-MSH) has an important role in modulating immunity and homeostasis. …”
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76
Changes in Ghrelin-Related Factors in Gastroesophageal Reflux Disease in Rats
Published 2013-01-01“…Therefore, these results suggest that aberrantly increased secretion of peripheral ghrelin and decreased ghrelin responsiveness may occur in GERD rats. Neuropeptide Y and agouti-related peptide mRNA expression in the hypothalamus of GERD rats was significantly increased, whereas proopiomelanocortin mRNA expression was significantly decreased compared to that in sham-operated rats. …”
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77
Pituitary Adenylate Cyclase-Activating Polypeptide Protects Glomerular Podocytes from Inflammatory Injuries
Published 2015-01-01“…Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide, which was originally isolated from the ovine hypothalamus and reportedly has diverse biological functions. …”
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78
Neurochemical Plasticity of the Coeliac-Superior Mesenteric Ganglion Complex Neurons Projecting to the Prepyloric Area of the Porcine Stomach following Hyperacidity
Published 2016-01-01“…In the control animals, FB-positive perikarya displayed immunoreactivity to tyrosine hydroxylase (TH), dopamine β-hydroxylase (DβH), neuropeptide Y (NPY), and galanin (GAL). Experimentally induced gastric hyperacidity changed the neurochemical phenotype of the studied neurons. …”
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79
Insulin Detemir Causes Lesser Weight Gain in Comparison to Insulin Glargine: Role on Hypothalamic NPY and Galanin
Published 2014-01-01“…This study investigated whether this effect was achieved by influencing the hypothalamic appetite regulators neuropeptide Y (NPY) and galanin (GAL). Methods. Type 2 diabetic rat models were established with a high-fat diet and intraperitoneal injection of STZ. …”
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Drosulfakinin signaling encodes early-life memory for adaptive social plasticity
Published 2024-12-01“…In particular, social deprivation suppressed the expression of the neuropeptide Drosulfakinin (Dsk) in three pairs of adult brain neurons. …”
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