An approach for accurate identification and monitoring of species in mangrove forests based on multi-source spectral data and deep learning by Monterrubio-Martínez Erandi, Trujillo-Acatitla Rubicel, Tuxpan-Vargas José, Moreno-Casasola Patricia

“…The computational experiments for MLP models involve different number of neurons and hidden layers. The best models for detecting mangrove forest achieved an accuracy of 99.95 % for training and 99.8 % for test, while for monospecific mangrove forest, at the species level, it attained an accuracy of 98.73 % for training and 96.84 % for test, in both cases the models demonstrated a great performance test for segmentation of different kind of mangrove forests. …”
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Oxidized DJ-1 Levels in Urine Samples as a Putative Biomarker for Parkinson’s Disease by Jihoon Jang, Soyeon Jeong, Sung Ik Lee, Wongi Seol, Hyemyung Seo, Ilhong Son, Dong Hwan Ho

“…Numerous reports have demonstrated that oxidative stress aggravates cytotoxicity in dopaminergic neurons and accelerates the formation of protein inclusions. …”
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Assessment of the Chemical Diversity and Functional Properties of Secondary Metabolites from the Marine Fungus <i>Asteromyces cruciatus</i> by María Paz González-Troncoso, Catalina Landeta-Salgado, Javiera Munizaga, Ruth Hornedo-Ortega, María del Carmen García-Parrilla, María Elena Lienqueo

“…Additionally, no detrimental effects were observed on a neuronal cell line. These findings highlight the influence of carbon sources on the production of bioactive metabolites and their functional properties, providing valuable insights into the biotechnological potential of <i>A. cruciatus</i>.…”
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Integrated Transcriptome Analysis Reveals Novel Molecular Signatures for Schizophrenia Characterization by Tong Ni, Yu Sun, Zefeng Li, Tao Tan, Wei Han, Miao Li, Li Zhu, Jing Xiao, Huiying Wang, Wenpei Zhang, Yitian Ma, Biao Wang, Di Wen, Teng Chen, Justin Tubbs, Xiaofeng Zeng, Jiangwei Yan, Hongsheng Gui, Pak Sham, Fanglin Guan

“…The analysis identified 184 DREGs forming an interconnected network involved in synaptic plasticity, inflammation, neuronal development, and neurotransmission. DREGs exhibited distinct expression in SCZ‐related brain regions and animal models. …”
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Investigation of PACAP Fragments and Related Peptides in Chronic Retinal Hypoperfusion by Dora Werling, Dora Reglodi, Peter Kiss, Gabor Toth, Krisztina Szabadfi, Andrea Tamas, Zsolt Biro, Tamas Atlasz

“…Pituitary adenylate cyclase activating polypeptide (PACAP) has neuroprotective effects in different neuronal and retinal injuries. Retinal ischemia can be effectively modelled by permanent bilateral common carotid artery occlusion (BCCAO), which causes chronic hypoperfusion-induced degeneration in the entire rat retina. …”
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Integrated multi-omics analysis reveals the underlying molecular mechanism for the neurotoxicity of triclosan in zebrafish by Shasha Zhao, Yuhang Ling, Baohua Zhang, Danting Wang, Limei Sun

“…Histopathological investigations and neural ultrastructural observations demonstrated that TCS could induce variable levels of pyknosis and vacuolation in the cytoplasm of neurons as well as torn mitochondrial membranes, shrinkage and broken or absent cristae. …”
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Parametrization of the dying brain: A case report from ICU bed-side EEG monitoring by Sebastian Zinn, Srdjan Z. Dragovic, Jan A. Kloka, Laurent M. Willems, Sebastian Harder, Stephan Kratzer, Kai D. Zacharowski, Gerhard Schneider, Paul S. García, Matthias Kreuzer

“…Although still fundamentally unique, the neuronal activity present in the dying brain is more similar to REM sleep than any other state we tested. …”
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Advancing Alzheimer's Therapy: Computational strategies and treatment innovations by Jibon Kumar Paul, Abbeha Malik, Mahir Azmal, Tooba Gulzar, Muhammad Talal Rahim Afghan, Omar Faruk Talukder, Samar Shahzadi, Ajit Ghosh

“…Alzheimer's disease (AD) is a multifaceted neurodegenerative condition distinguished by the occurrence of memory impairment, cognitive deterioration, and neuronal impairment. Despite extensive research efforts, conventional treatment strategies primarily focus on symptom management, highlighting the need for innovative therapeutic approaches. …”
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Whole exome sequencing identifies ABHD14A and MRNIP as novel candidate genes for developmental language disorder by Amal Bouzid, Malek Belcadhi, Amal Souissi, Meryam Chelly, Fakher Frikha, Hela Gargouri, Crystel Bonnet, Fida Jebali, Salma Loukil, Christine Petit, Saber Masmoudi, Rifat Hamoudi, Mariem Ben Said

“…Biological functions and interconnections analyses predicted the potential roles of ABHD14A and MRNIP in neuronal development pathways. These results suggest ABHD14A and MRNIP, as putative candidate genes for DLD susceptibility. …”
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Electroacupuncture Improved Hippocampal Neurogenesis following Traumatic Brain Injury in Mice through Inhibition of TLR4 Signaling Pathway by Yuqin Ye, Yongxiang Yang, Chen Chen, Ze Li, Yanfeng Jia, Xinhong Su, Chaoxian Wang, Xiaosheng He

“…BrdU/NeuN immunofluorescence was performed to label newborn neurons in the hippocampus after EA treatment. Water maze test and neurological severity score were used to evaluate neurological function posttrauma. …”
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Schwann Cell‐Specific Ablation of Beclin 1 Impairs Myelination and Leads to Motor and Sensory Neuropathy in Mice by Lisa Gambarotto, Loris Russo, Silvia Bresolin, Luca Persano, Rachele D'Amore, Giulia Ronchi, Federica Zen, Luisa Muratori, Alice Cani, Samuele Negro, Aram Megighian, Sonia Calabrò, Paola Braghetta, Dario Bizzotto, Matilde Cescon

“…Abstract The core component of the class III phosphatidylinositol 3‐kinase complex, Beclin 1, takes part in different protein networks, thus switching its role from inducing autophagy to regulating autophagosomal maturation and endosomal trafficking. While assessed in neurons, astrocytes, and microglia, its role is far less investigated in myelinating glia, including Schwann cells (SCs), responsible for peripheral nerve myelination. …”
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Efficacy of human umbilical cord mesenchymal stem cell in the treatment of neuromyelitis optica spectrum disorders: an animal study by Chunran Xue, Haojun Yu, Xuzhong Pei, Xiaoying Yao, Jie Ding, Xiying Wang, Yi Chen, Yangtai Guan

“…Results hUC-MSCs alleviated NMOSD progression in vivo with improved motor function, reduced inflammatory infiltration, myelin loss, and preservation of astrocytes and neurons. hUC-MSC treatment did not affect autoimmune reactions in the spleen, however, decreased cytokine release in the spinal cord and mitigated blood–brain barrier disruption. …”
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Detección de estrés por medio de redes neuronales artificiales en personal sanitario by Carlos Eduardo Cañedo Figueroa, Xóchitl Duque Alarcón, María Teresa Silvia Tinoco Zamudio

“…Se generó un modelo de red neuronal para clasificar datos relacionados con la detección oportuna de problemas de estrés en personal sanitario. …”
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Dystonia caused by ANO3 variants is due to attenuated Ca2+ influx by ORAI1 by Jiraporn Ousingsawat, Khaoula Talbi, Hilario Gómez-Martín, Anne Koy, Alberto Fernández-Jaén, Hasan Tekgül, Esra Serdaroğlu, Juan Darío Ortigoza-Escobar, Rainer Schreiber, Karl Kunzelmann

“…Conclusions Dysregulated Ca2+ signaling by ANO3 variants may impair the activation of K+ channels in striatal neurons of the brain, thereby causing dystonia. Furthermore, the data provide a first indication of a possible regulation of protein expression in the plasma membrane by ANO3, as has been described for other anoctamins.…”
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Metabolites derived from medicinal plants modulating voltage-gated sodium channel activity: A systematic review by José Luis Estela-Zape, Mayra Liliana Pizarro-Loaiza, Gabriel Arteaga, Santiago Castaño, Leonardo Fierro

“…Background: Voltage-gated sodium channels (Nav) are critical for generating action potentials in neuronal and muscle tissues. Dysfunction of these channels is associated with neurological disorders such as epilepsy, neuropathic pain, and myopathies. …”
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Environmental Enrichment Induces Changes in Long-Term Memory for Social Transmission of Food Preference in Aged Mice through a Mechanism Associated with Epigenetic Processes by Simona Cintoli, Maria Cristina Cenni, Bruno Pinto, Silvia Morea, Alessandro Sale, Lamberto Maffei, Nicoletta Berardi

“…We found that only EE mice successfully performed the remote memory recall task, showed neuronal activation in OFC, assessed with c-fos immunohistochemistry and early tagging of OFC, assessed with histone H3 acetylation, suggesting a defective system consolidation and early OFC tagging in aged mice which are ameliorated by EE.…”
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Brain 18FDG-PET pattern in cognitively impaired elderly patients with bipolar disorder by Nouredine Saleh, Capucine Blaise, Amina Daoudi, Matthieu Queneau, Karim Fard, Julien Dumurgier, Esteban Munoz-Musat, Emeline Marlinge, Jacques Hugon, Claire Hourregue, Claire Paquet, Emmanuel Cognat

“…FDG-PET elucidates glucose metabolic reductions due to altered neuronal activity in the cerebral cortex, allowing detection and identification of neurodegenerative processes. …”
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Altered Forebrain Functional Connectivity and Neurotransmission in a Kinase-Inactive Mouse Model of Autism by Shiyu Tang PhD, Elizabeth M. Powell PhD, Wenjun Zhu MS, Fu-Sun Lo MD, Reha S. Erzurumlu PhD, Su Xu PhD

“…We employed resting-state functional magnetic resonance imaging and in vivo high-resolution proton MR spectroscopy to examine neuronal connectivity and neurotransmission of wild-type, heterozygous Met–Emx1 , and fully inactive homozygous Met–Emx1 mice. …”
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A new immunofluorescence determination of Parkinson's disease biomarkers using silver nanoparticles by Chao Qin, Jun Xia, Yong Wen, Jun Wang, Chen Zhong

“…Parkinson's disease (PD) is a neurodegenerative condition marked by a steady loss of dopaminergic neurons in the brain's substantia nigra. Prompt identification and tracking of PD progression are essential for prompt intervention and efficient PD care. …”
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Xenopus laevis neural stem progenitor cells exhibit a transient metabolic shift toward glycolysis during spinal cord regeneration by Paula G. Slater, Paula G. Slater, Miguel E. Domínguez-Romero, Guillermo Campos, Guillermo Campos, Vania Aravena, Vania Aravena, Javier Cavieres-Lepe, Verónica Eisner

“…During Xenopus laevis spinal cord regeneration, neural stem precursor cells (NSPCs) surrounding the central canal rapidly proliferate in response to SCI, compensating for cellular loss, restoring canal continuity, and generating new neurons to reestablish lost connections. It has been described that mitochondria and cellular metabolism play essential roles in stem cell proliferation, self-renewal, and differentiation. …”
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