Biochemical analysis to study wild-type and polyglutamine-expanded ATXN3 species. by Grégoire Quinet, María Cristina Paz-Cabrera, Raimundo Freire

“…Spinocerebellar ataxia type 3 (SCA3) is a cureless neurodegenerative disease recognized as the most prevalent form of dominantly inherited ataxia worldwide. …”
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Is Parkinson’s Disease Truly a Prion-Like Disorder? An Appraisal of Current Evidence by Aneesha Chauhan, Alexander F. Jeans

“…Parkinson’s disease (PD) is the world’s second most common neurodegenerative disease and most common movement disorder. …”
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Advancements in the Use of Hydrogels for Regenerative Medicine: Properties and Biomedical Applications by Andrea Revete, Andrea Aparicio, Bruno A. Cisterna, Javier Revete, Luis Luis, Ernesto Ibarra, Edwin A. Segura González, Jay Molino, Diego Reginensi

“…This reason presents them as an exciting alternative to highly complex human physiological problems, such as injuries to the central nervous system and neurodegenerative disease.…”
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Schwann Cells in Neuromuscular Disorders: A Spotlight on Amyotrophic Lateral Sclerosis by Kathryn R. Moss, Smita Saxena

“…Amyotrophic Lateral Sclerosis (ALS) is a complex neurodegenerative disease primarily affecting motor neurons, leading to progressive muscle atrophy and paralysis. …”
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Mesenchymal Stem Cells: A Potential Therapeutic Approach for Amyotrophic Lateral Sclerosis? by Agnese Gugliandolo, Placido Bramanti, Emanuela Mazzon

“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the degeneration of both upper and lower motor neurons. …”
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Case report: Significant lesion reduction and neural structural changes following ibogaine treatments for multiple sclerosis by David Qixiang Chen, José Adalberto Inzunza Domínguez, Juan Manuel Valle Uzeta, Abhiram P. Pushparaj, Abhiram P. Pushparaj, Jonathan E. Dickinson

“…Multiple sclerosis (MS) is a debilitating neurodegenerative disease characterized by demyelination and neuronal loss. …”
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Insight into the Molecular Imaging of Alzheimer’s Disease by Abishek Arora, Neeta Bhagat

“…Alzheimer’s disease is a complex neurodegenerative disease affecting millions of individuals worldwide. …”
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deutetrabenazine for the treatment of chorea associated with Huntington’s disease by Harshit Gupta, Wil Perkins, Cain Stark, Sathya Kikkeri, Juyeon Kakazu, Adam D. Kaye, Alan D. Kaye

“…Unfortunately, treatment has been limited for many aspects of this neurodegenerative disease. The present investigation presents the background, evidence, and indications for the use Deutetrabenazine in the setting of Huntington’s disease. …”
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Long-Term Provision of Acidified Drinking Water Fails to Influence Autoimmune Diabetes and Encephalomyelitis by Sundararajan Jayaraman, Arathi Jayaraman

“…Interestingly, administration of complete Freund’s adjuvant alone or emulsified with a neuronal peptide to induce neurodegenerative disease during the prediabetic stage completely prevented the onset of diabetes regardless of the pH of the drinking water. …”
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Ensemble-Based Alzheimer's Disease Classification Using Features Extracted from Hog Descriptor and Pre-trained Models by Enver Akbacak, Nedim Muzoglu

“…Alzheimer's Disease is the most common type of dementia and is a progressive, neurodegenerative disease. The disease worsens over time, and the patient becomes bedridden, unable to move or understand what is happening around him. …”
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The Genetics of Alzheimer’s Disease by Robert C. Barber

“…Alzheimer’s disease is a progressive, neurodegenerative disease that represents a growing global health crisis. …”
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Mechanisms and active substances of targeting lipid peroxidation in ferroptosis regulation by Hui Chen, Lingli Chen, Wenjun Wang

“…Ferroptosis is a novel form of cell death driven by iron-dependent lipid peroxidation and it is implicated in various diseases, such as liver disease, acute kidney injury, cardiovascular disease, neurodegenerative disease and cancer. Lipid-based reactive oxygen species (ROS), particularly lipid hydroperoxides in the cellular membrane can lead to membrane disruption and cell death mediated by ferroptosis. …”
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Toll-Like Receptor 4: A Promising Therapeutic Target for Alzheimer’s Disease by Linyu Wu, Xiaohui Xian, Guangyu Xu, Zixuan Tan, Fang Dong, Min Zhang, Feng Zhang

“…Alzheimer’s disease (AD) is a progressive neurodegenerative disease that primarily manifests as memory deficits and cognitive impairment and has created health challenges for patients and society. …”
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Detection of fungal sequences in human brain: rDNA locus amplification and deep sequencing by Rodrigo Leitao, Iam Ut Wan, Harry Chown, Thomas J. Williams, Matthew C. Fisher, Johanna Rhodes

“…This approach would be well-placed to investigate potential links between microbial infection and neurodegenerative disease.…”
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Machine learning identified novel players in lipid metabolism, endosomal trafficking, and iron metabolism of the ALS spinal cord by Jack Cheng, Bor-Tsang Wu, Hsin-Ping Liu, Wei-Yong Lin

“…Abstract Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting motor neurons. Although genes causing familial cases have been identified, those of sporadic ALS, which occupies the majority of patients, are still elusive. …”
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Functional connectivity within sensorimotor cortical and striatal regions is regulated by sepsis in a sex-dependent manner by Quan Vo, Zachary D. Simon, Gwoncheol Park, Dina C Nacionales, Carmelina Gorski, Evan L Barrios, Gemma Casadesus, Philip A Efron, Lyle L Moldawer, Ravinder Nagpal, Paramita Chakrabarty, Marcelo Febo

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Comparison of Diffusion Tensor Imaging Metrics in Normal-Appearing White Matter to Cerebrovascular Lesions and Correlation with Cerebrovascular Disease Risk Factors and Severity by Seyyed M. H. Haddad, Christopher J. M. Scott, Miracle Ozzoude, Courtney Berezuk, Melissa Holmes, Sabrina Adamo, Joel Ramirez, Stephen R. Arnott, Nuwan D. Nanayakkara, Malcolm Binns, Derek Beaton, Wendy Lou, Kelly Sunderland, Sujeevini Sujanthan, Jane Lawrence, Donna Kwan, Brian Tan, Leanne Casaubon, Jennifer Mandzia, Demetrios Sahlas, Gustavo Saposnik, Ayman Hassan, Brian Levine, Paula McLaughlin, J. B. Orange, Angela Roberts, Angela Troyer, Sandra E. Black, Dar Dowlatshahi, Stephen C. Strother, Richard H. Swartz, Sean Symons, Manuel Montero-Odasso, null ONDRI Investigators, Robert Bartha

“…DTI metrics including fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), and radial diffusivity (RD) were measured in cerebral tissues and cerebrovascular anomalies from 152 people with CVD participating in the Ontario Neurodegenerative Disease Research Initiative (ONDRI). Ten cerebral tissue types were segmented including NAWM, and vascular lesions including stroke, periventricular and deep white matter hyperintensities, periventricular and deep lacunar infarcts, and perivascular spaces (PVS) using T1-weighted, proton density-weighted, T2-weighted, and fluid attenuated inversion recovery MRI scans. …”
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An Optimized Hybrid PSO-ELM for Parkinson’s Disease Diagnosis by Gunakala Archana, Afzal Hussain Shahid

“…Parkinson’s disease (PD) is a neurodegenerative disease that gradually causes movement impairment and various symptoms. …”
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Neuroinflammation and ALS: Transcriptomic Insights into Molecular Disease Mechanisms and Therapeutic Targets by Giovanna Morello, Antonio Gianmaria Spampinato, Sebastiano Cavallaro

“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting the motor nervous system. …”
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In Vitro Characterization of Motor Neurons and Purkinje Cells Differentiated from Induced Pluripotent Stem Cells Generated from Patients with Autosomal Recessive Spastic Ataxia of... by Aurélie Louit, Marie-Josée Beaudet, Mathieu Blais, François Gros-Louis, Nicolas Dupré, François Berthod

“…Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is an early-onset neurodegenerative disease mainly characterized by spasticity in the lower limbs and poor muscle control. …”
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