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361
Oligodendrocyte precursor cells facilitate neuronal lysosome release
Published 2025-01-01“…Our findings have implications for the prevention of age-related pathologies and the treatment of neurodegenerative diseases.…”
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362
Illuminating the impact of N-terminal acetylation: from protein to physiology
Published 2025-01-01“…At the organismal level, N-terminal acetylation is highly influential, and its impairment was recently linked to cardiac dysfunction and neurodegenerative diseases.…”
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363
Bioactive compounds in Hericium erinaceus and their biological properties: a review
Published 2024-07-01“…It is also effective in protecting the digestive system and preventing neurodegenerative diseases. In this review paper, we summarize the sources, structures and eff icacies of the main active components in H. erinaceus fruiting body, mycelium, and culture media, and update the latest research progress on their biological activities and the related molecular mechanisms. …”
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364
Levodopa Responsive Parkinsonism in Patients with Hemochromatosis: Case Presentation and Literature Review
Published 2017-01-01“…Accumulation of iron in the brain has been postulated to be associated with several neurodegenerative diseases including Parkinson’s disease. The excess iron promotes Parkin and α-synuclein aggregation in the neurons. …”
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365
Non-invasive brain stimulation in cognitive sciences and Alzheimer's disease
Published 2025-01-01“…In the present paper, basic physiological and technical mechanisms and different applications of NIBS were reviewed and discussed to highlight the importance of NIBS in multidisciplinary and translational approaches in clinical and research settings of cognitive sciences and neurodegenerative diseases, especially in Alzheimer's disease. …”
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366
The Genetics of Parkinson’s Disease
Published 2024-02-01“…Parkinson's disease (PD) is one of the most common neurodegenerative diseases worldwide. Approximately 15% of PD patients have a family history of the disease in one or more first-degree relatives, and 5-10% of PD cases exhibit a classical Mendelian inheritance pattern. …”
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367
Neurobiology of Vascular Dementia
Published 2011-01-01“…However, in a very large majority of cases, these alterations occur in an already aged brain, characterized by a milieu of cellular and molecular events common for different neurodegenerative diseases. The cell signaling defects and molecular dyshomeostasis might lead to neuronal malfunction prior to the death of neurons and the alteration of neuronal networks. …”
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368
Contribution of Microglia-Mediated Neuroinflammation to Retinal Degenerative Diseases
Published 2015-01-01“…One common feature of retinal degenerative diseases and brain neurodegenerative diseases is chronic neuroinflammation. There is growing evidence that retinal microglia, as in the brain, become activated in the course of retinal degenerative diseases, having a pivotal role in the initiation and propagation of the neurodegenerative process. …”
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369
Role of Neuroinflammation in Adult Neurogenesis and Alzheimer Disease: Therapeutic Approaches
Published 2013-01-01“…Neuroinflammation, a specialized immune response that takes place in the central nervous system, has been linked to neurodegenerative diseases, and specially, it has been considered as a hallmark of Alzheimer disease, the most common cause of dementia in the elderly nowadays. …”
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370
Programmed neurite degeneration in human central nervous system neurons driven by changes in NAD+ metabolism
Published 2025-01-01“…Abstract Neurite degeneration (ND) precedes cell death in many neurodegenerative diseases. However, it remains unclear how this compartmentalized cell death process is orchestrated in the central nervous system (CNS). …”
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371
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The neurotoxicity of iodoacetic acid, a byproduct of drinking water disinfection
Published 2025-01-01“…In neurological manifestations, IAA can lead to neurotransmitter disorders, neurodevelopment dysfunction, and even neurodegenerative diseases. Taken together, our review provides insights into the mechanisms of IAA neurotoxicity that will contribute to future studies of IAA neurotoxicity and its protective strategies.…”
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373
Targeting Mitochondrial Dysfunction in Cerebral Ischemia: Advances in Pharmacological Interventions
Published 2025-01-01“…This article highlights the critical role of mitochondrial dysfunction in the progression of neurodegenerative diseases and discusses the need for targeted therapeutic strategies to attenuate cellular damage, restore mitochondrial function, and enhance neuroprotection.…”
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374
Configuration of health pathway networks for patients with chronic diseases
Published 2024-01-01“…Chronic and long-term diseases, particularly neurodegenerative diseases and polymorbidity, are increasingly occupying the medical and socio-medical landscape and are a concern for government policies. …”
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375
Brain Plasticity and Cell Competition: Immediate Early Genes Are the Focus
Published 2025-01-01“…This work might inspire new gene therapy strategies targeting IEGs to regulate synaptic plasticity, and potentially prevent or mitigate neurodegenerative diseases.…”
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376
Consequences of Repetitive Head-Impact Exposure in Sports - literature review
Published 2025-01-01“… Repetitive head impacts (RHIs), common in contact sports, have raised concerns about their long-term effects on brain health, potentially leading to conditions like concussions, Chronic Traumatic Encephalopathy (CTE), and other neurodegenerative diseases. CTE, a progressive tauopathy, is associated with cognitive and psychological symptoms, including memory loss and depression. …”
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377
An Overview of DNA Repair in Amyotrophic Lateral Sclerosis
Published 2011-01-01“…Moreover, biochemical and genetic data on DNA repair in ALS are discussed in light of similar findings in other neurodegenerative diseases.…”
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378
Exploring the diversity of cannabis cannabinoid and non-cannabinoid compounds and their roles in Alzheimer's disease: A review
Published 2025-06-01“…Cannabis sativa is recognized for its chemical diversity and therapeutic potential, particularly in addressing neurodegenerative diseases such as Alzheimer's disease (AD). …”
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379
Statistical Complexity Analysis of Sleep Stages
Published 2025-01-01“…Studying sleep stages is crucial for understanding sleep architecture, which can help identify various health conditions, including insomnia, sleep apnea, and neurodegenerative diseases, allowing for better diagnosis and treatment interventions. …”
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380
TSE Diagnostics: Recent Advances in Immunoassaying Prions
Published 2013-01-01“…Transmissible spongiform encephalopathies (TSEs) or prion diseases are a group of rare fatal neurodegenerative diseases, affecting humans and animals. They are believed to be the consequence of the conversion of the cellular prion protein to its aggregation-prone, β-sheet-rich isoform, named prion. …”
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