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341
Antioxidant and Neuroproliferative Effects of THL-3-PTD5 Peptide Derived from Hydramacin-1 Antimicrobial Peptide
Published 2024-01-01“…This study suggests that THL-3-PTD5 may serve as a potential candidate for developing therapeutic agents against neurodegenerative diseases.…”
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342
Tau phosphorylation suppresses oxidative stress-induced mitophagy via FKBP8 receptor modulation.
Published 2025-01-01“…Neurodegenerative diseases are often characterized by mitochondrial dysfunction. …”
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343
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344
Innate Immunity and Neuroinflammation
Published 2013-01-01“…Neuroinflammation occurs in close relation to trauma, infection, and neurodegenerative diseases. Low-level neuroinflammation is considered to have beneficial effects whereas chronic neuroinflammation can be harmful. …”
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345
A Review of the Effects of Physical Activity and Exercise on Cognitive and Brain Functions in Older Adults
Published 2013-01-01“…Together these finding suggest that physical exercise is a promising nonpharmaceutical intervention to prevent age-related cognitive decline and neurodegenerative diseases.…”
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346
Amyloid-Beta Induced Changes in Vesicular Transport of BDNF in Hippocampal Neurons
Published 2016-01-01“…Deficits in transport of this secretory protein could underlie neurodegenerative diseases. Investigation of disease-related changes in BDNF transport might provide insights into the cellular mechanism underlying, for example, Alzheimer’s disease (AD). …”
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347
Sex differences in the association between repetitive negative thinking and neurofilament light
Published 2024-11-01“…Given that women have a greater risk of many neurodegenerative diseases, this study investigated whether worry and brooding are associated with general neurodegeneration and whether associations differ by sex. …”
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348
Protective effects of wogonin in the treatment of central nervous system and degenerative diseases
Published 2025-02-01“…Moreover, wogonin shows promise in treating neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease by promoting autophagy and reducing neuroinflammation. …”
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349
Anti-Neuroinflammatory Effects of Prenylated Indole Alkaloids from the Antarctic Fungus <i>Aspergillus</i> sp. Strain SF-7367
Published 2025-01-01“…Inflammation has always been considered a trigger or consequence of neurodegenerative diseases, and the inhibition of inflammation in the central nervous system can effectively protect nerve cells. …”
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350
Epigenetic and Neurological Impairments Associated with Early Life Exposure to Persistent Organic Pollutants
Published 2019-01-01“…The incidence of neurodevelopmental and neurodegenerative diseases worldwide has dramatically increased over the last decades. …”
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351
A synthesized view of the CSF-blood barrier and its surgical implications for aging disorders
Published 2025-02-01“…Finally, we discuss the implications of flow dysregulation in the context of neurodegenerative diseases and discuss the rising role of perivascular drainage pathways including glymphatics.…”
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352
Novel Role of Pin1-Cis P-Tau-ApoE Axis in the Pathogenesis of Preeclampsia and Its Connection with Dementia
Published 2024-12-01“…Despite impressive research and therapeutic advances in both fields of preE and neurodegenerative diseases, further investigation of Pin1-cis P-tau and ApoE-related mechanistic underpinnings may unravel novel therapeutic options, and new transcriptional and proteomic markers. …”
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353
Changes in RNA Splicing: A New Paradigm of Transcriptional Responses to Probiotic Action in the Mammalian Brain
Published 2025-01-01“…Protein–protein interactions and a KEGG analysis of differentially spliced genes (DSGs) revealed consistent enrichment in the spliceosome and vesicle transport complexes, as well as in pathways related to neurodegenerative diseases, synaptic function and plasticity, and substance addiction across brain regions. …”
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354
CD22 modulation alleviates amyloid β-induced neuroinflammation
Published 2025-02-01“…Yet, therapeutic targets for neurodegenerative diseases based on neuroinflammation still warrant investigation. …”
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355
Risk Factors for Infection Associated with Ischemic Stroke in Patients over 60 Years of Age
Published 2024-09-01“…<br /><strong>Conclusions:</strong> the severity of ischemic stroke, the coexistence of neurodegenerative diseases and dysphagia constitute the main risk factors for infection associated with ischemic stroke in patients over 60 years of age.…”
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356
Impact of glycolysis inhibitor (2-DG) and oxidation and phosphorylation uncoupler (2,4-DNP) on brain metabolites
Published 2018-04-01“…A deficiency of available energy for brain cells under neurodegenerative diseases is either developed due to age-dependent underexpression of genes that encode glycolytic enzymes or induced due to the uncoupling of oxidation and phosphorylation that could be mediated by inflammatory cytokines. …”
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357
Magnetic resonance imaging in primates. The example of the mouse lemur (Microcebus murinus): From detection of pathological aging to therapeutic evaluations
Published 2011-02-01“…It leads in many cases to neurodegenerative diseases such as Alzheimer disease (AD). Rodents and particularly transgenic mice are widely used as models for research on physiopathology of cerebral aging, neurodegenerative diseases and for the evaluation of therapies. …”
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358
Alginate: Current Use and Future Perspectives in Pharmaceutical and Biomedical Applications
Published 2016-01-01“…The recent technological advancements with using alginates, issues related to alginates suitability as matrix for three-dimensional tissue cultures, adjuvants of antibiotics, and antiviral agents in cell transplantation in diabetes or neurodegenerative diseases treatment, and an update on the antimicrobial and antiviral therapy of the alginate based drugs are also highlighted.…”
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359
Parkinson's Disease: Is It a Toxic Syndrome?
Published 2010-01-01“…Parkinson's disease (PD) is one of the neurodegenerative diseases which we can by certainty identify its pathology, however, this confidence disappeares when talking about the cause. …”
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360
Stat3 mediates Fyn kinase-driven dopaminergic neurodegeneration and microglia activation
Published 2024-12-01Get full text
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