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Network pharmacology study on the mechanism of berberine in Alzheimer’s disease model
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Distinct regulation of Tau Monomer and aggregate uptake and intracellular accumulation in human neurons
Published 2024-12-01Get full text
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305
Protective effects of apigenin in neurodegeneration: An update on the potential mechanisms
Published 2025-03-01“…Neurodegenerative diseases (NDs) are characterized by the progressive loss of neurons and neuronal connections, leading to cognitive decline, memory impairment, and motor dysfunction. …”
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COMPARISON OF COGNITIVE FUNCTION AND DEPRESSIVE SYMPTOMS IN INSTITUTIONALIZED HEALTHY AND OLDER PERSON WITH ALZHEIMER’S DISEASE
Published 2024-09-01“…So, the purpose of this study was to compare cognitive function and depressive symptoms in two groups: a group of older adults with Alzheimer’s disease and a group of older adults without neurodegenerative diseases, by sex and level of physical activity. …”
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4-Hydroxycinnamic acid attenuates neuronal cell death by inducing expression of plasma membrane redox enzymes and improving mitochondrial functions
Published 2023-07-01“…Many approaches to neurodegenerative diseases that focus on amyloid-β clearance and gene therapy have not been successful. …”
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309
Toll-Like Receptors Expression and Signaling in Glia Cells in Neuro-Amyloidogenic Diseases: Towards Future Therapeutic Application
Published 2010-01-01“…While TLR signaling was linked to neurogenesis, it was also found to be involved in the pathogenesis of neurodegenerative diseases. This paper will focus on TLR signaling in glial cells in neurodegenerative diseases such as Alzheimer's disease, prion diseases, amyotrophic lateral sclerosis, and Parkinson's disease. …”
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310
The Emerging Role of Proteolysis in Mitochondrial Quality Control and the Etiology of Parkinson’s Disease
Published 2012-01-01“…Mitochondrial biology and dysfunction have recently been linked to different types of cancers and neurodegenerative diseases, most notably Parkinson’s disease. …”
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311
Dynamics of retinal changes in early-stage Parkinson’s disease
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312
Omega-3 Fatty Acids: Key Players in Cognitive Function and Brain Health
Published 2025-01-01“…Modern diets, often lacking in omega-3, highlight their importance in combating cognitive decline, neurodegenerative diseases, and mental disorders. Purpose of research: This study explores the roles of omega-3 fatty acids in brain health and cognitive functions, including their mechanisms of action and potential in preventing and alleviating neurodegenerative diseases. …”
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MitoSeg: Mitochondria segmentation tool
Published 2025-05-01“…Recent studies suggest a potential link between the physical structure of mitochondria and neurodegenerative diseases. With advances in Electron Microscopy techniques, it has become possible to visualize the boundary and cristae structures of mitochondria in detail. …”
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314
Strategies for Regenerating Striatal Neurons in the Adult Brain by Using Endogenous Neural Stem Cells
Published 2011-01-01“…Currently, there is no effective treatment for the marked neuronal loss caused by neurodegenerative diseases, such as Huntington's disease (HD) or ischemic stroke. …”
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The Emerging Roles of the Calcineurin-Nuclear Factor of Activated T-Lymphocytes Pathway in Nervous System Functions and Diseases
Published 2016-01-01“…The ongoing epidemics of metabolic diseases and increase in the older population have increased the incidences of neurodegenerative diseases. Evidence from murine and cell line models has implicated calcineurin-nuclear factor of activated T-lymphocytes (NFAT) signaling pathway, a Ca2+/calmodulin-dependent major proinflammatory pathway, in the pathogenesis of these diseases. …”
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Change of Accent as an Atypical Onset of non Fluent Primary Progressive Aphasia
Published 2013-01-01“…Language disorders can be the first symptom of many neurodegenerative diseases, including Alzheimer's disease (AD) and primary progressive aphasia (PPA). …”
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Application of antisense oligonucleotide drugs in amyotrophic lateral sclerosis and Huntington’s disease
Published 2025-01-01“…Currently, available treatments for various neurodegenerative diseases can alleviate symptoms but do not provide a definitive cure. …”
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Protocol for live imaging of axonal transport in iPSC-derived iNeurons
Published 2025-03-01“…Summary: Studies of human induced pluripotent stem cell (iPSC)-derived neurons promise important insights into neurodegenerative diseases. Here, we present a protocol for live imaging of axonal transport in glutamatergic iPSC-derived neurons (iNeurons). …”
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Human Endogenous Retroviruses and Their Putative Role in Pathogenesis of Alzheimer’s Disease, Inflammation, and Senescence
Published 2024-12-01“…The article aims to highlight the potential role of HERVs in neurodegenerative diseases such as Alzheimer’s disease and senescence. …”
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Linking Neuroinflammation and Neurodegeneration in Parkinson’s Disease
Published 2018-01-01“…Neurodegenerative diseases such as Parkinson’s disease (PD) and Alzheimer’s disease (AD) impose a pressing burden on our developed and consequently aging society. …”
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