Lipid Oxidation at the Crossroads: Oxidative Stress and Neurodegeneration Explored in <i>Caenorhabditis elegans</i> by Julia Tortajada-Pérez, Andrea del Valle Carranza, Cristina Trujillo-del Río, Mar Collado-Pérez, José María Millán, Gema García-García, Rafael Pascual Vázquez-Manrique

“…The findings from <i>Caenorhabditis elegans</i> studies offer valuable insights into these complex processes and highlight potential avenues for developing targeted therapies to mitigate neurodegenerative disease progression.…”
Get full text

Temporal and spatial pattern of DNA damage in neurons following spinal cord Injury in mice by Elle EM Scheijen, Naomi Veeningen, Sam Duwé, Anna Ivanova, Jana Van Broeckhoven, Sven Hendrix, David M Wilson

“…Abstract Background Deficient DNA repair and excessive DNA damage contribute to neurodegenerative disease. However, the role of DNA damage and repair in spinal cord injury (SCI) is unclear. …”
Get full text

Acupuncture for Parkinson’s Disease: Efficacy Evaluation and Mechanisms in the Dopaminergic Neural Circuit by Yadan Zhao, Zichen Zhang, Siru Qin, Wen Fan, Wei Li, Jingyi Liu, Songtao Wang, Zhifang Xu, Meidan Zhao

“…Parkinson’s disease (PD) is a chronic and progressive neurodegenerative disease caused by degeneration of dopaminergic neurons in the substantia nigra. …”
Get full text

Pharmacophore-based virtual screening for identification of marine sponge bioactive compound inhibitors against Alzheimer's disease by Suruthi SS, Prashanth KK, Baskaran A

“…Alzheimer's disease is a hereditary neurodegenerative disease that occurs sporadically and causes amnestic cognitive impairment. …”
Get full text

In vivo mapping of sodium homeostasis disturbances in individual ALS patients: A brain 23Na MRI study. by Aude-Marie Grapperon, Mohamed Mounir El Mendili, Adil Maarouf, Jean-Philippe Ranjeva, Maxime Guye, Annie Verschueren, Shahram Attarian, Wafaa Zaaraoui

“…<h4>Objective</h4>Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by significant heterogeneity among patients. 23Na MRI maps abnormal sodium homeostasis that reflects metabolic alterations and energetic failure contributing to the neurodegenerative process. …”
Get full text

Identifying the NEAT1/miR-26b-5p/S100A2 axis as a regulator in Parkinson's disease based on the ferroptosis-related genes. by Taole Li, Jifeng Guo

“…<h4>Objectives</h4>Parkinson's disease (PD) is a complex neurodegenerative disease with unclear pathogenesis. Some recent studies have shown that there is a close relationship between PD and ferroptosis. …”
Get full text

Extensive In Silico Analysis of ATL1 Gene : Discovered Five Mutations That May Cause Hereditary Spastic Paraplegia Type 3A by Mujahed I. Mustafa, Naseem S. Murshed, Abdelrahman H. Abdelmoneim, Miyssa I. Abdelmageed, Nafisa M. Elfadol, Abdelrafie M. Makhawi

“…Hereditary spastic paraplegia type 3A (SPG3A) is a neurodegenerative disease inherited type of Hereditary spastic paraplegia (HSP). …”
Get full text

LINC02282 promotes DNA methylation of TRIM6 by recruiting DNMTs to inhibit the progression of Parkinson's disease by Lu Han, Chuansheng Zhao, Feng Jin, Rongfeng Jiang, Hao Wu

“…Parkinson’s disease (PD) is the second most common neurodegenerative disease. Long non-coding RNAs (lncRNAs) are closely linked to the occurrence and development of neurodegenerative diseases, while the underlying mechanisms remain elusive. …”
Get full text

A robust Parkinson’s disease detection model based on time-varying synaptic efficacy function in spiking neural network by Priya Das, Sarita Nanda, Ganapati Panda, Sujata Dash, Amel Ksibi, Shrooq Alsenan, Wided Bouchelligua, Saurav Mallik

“…Abstract Parkinson’s disease (PD) is a neurodegenerative disease affecting millions of people around the world. …”
Get full text

Data Clustering Improves Siamese Neural Networks Classification of Parkinson’s Disease by Mohamed Shalaby, Nahla A. Belal, Yasser Omar

“…Parkinson’s disease (PD) is a clinical neurodegenerative disease having symptoms like tremor, rigidity, and postural disability. …”
Get full text

Sexual dimorphism in the sheep corpus callosum using 3 tesla MRI by Sedat Aydoğdu, Emrullah Eken, Mustafa Koplay

“…<p> <b>Conclusion:</b> It is thought that the findings obtained from healthy sheep brains in this study can be used in neurodegenerative disease models created in sheep in neuroscience studies and experimental studies.…”
Get full text

Cognitive enhancing effect of an extract of Swertia chirata against memory impairment induced by aluminum chloride by Reena Deshmukh, Manisha Jaiswal, Anshita Shukla, Umesh Patil, Mukesh Sharma

“…Background: The most advanced type of neurodegenerative disease, Alzheimer's disease (AD), significantly reduces cognitive performance. …”
Get full text

Oxidative stress and dysregulated long noncoding RNAs in the pathogenesis of Parkinson’s disease by Jialu Wang, Meitong Liu, Jiuhan Zhao, Pan Hu, Lianbo Gao, Shen Tian, Jin Zhang, Huayan Liu, Xiaoxue Xu, Zhenwei He

“…Abstract Parkinson’s disease (PD) is a progressive age-related neurodegenerative disease whose annual incidence is increasing as populations continue to age. …”
Get full text

Oxidized DJ-1 Levels in Urine Samples as a Putative Biomarker for Parkinson’s Disease by Jihoon Jang, Soyeon Jeong, Sung Ik Lee, Wongi Seol, Hyemyung Seo, Ilhong Son, Dong Hwan Ho

“…Parkinson’s disease (PD) is the second most common neurodegenerative disease. Oxidative stress is the most critical risk factor for neurodegenerative diseases, including Alzheimer’s disease (AD) and Huntington’s disease (HD). …”
Get full text

Age-Related Macular Degeneration: Insights into Inflammatory Genes by Raffaella Cascella, Michele Ragazzo, Claudia Strafella, Filippo Missiroli, Paola Borgiani, Francesco Angelucci, Luigi Tonino Marsella, Andrea Cusumano, Giuseppe Novelli, Federico Ricci, Emiliano Giardina

“…Age-related macular degeneration (AMD) is a progressive neurodegenerative disease that affects approximately 8.7% of elderly people worldwide (>55 years old). …”
Get full text

Early Electrophysiological Disintegration of Hippocampal Neural Networks in a Novel Locus Coeruleus Tau-Seeding Mouse Model of Alzheimer’s Disease by A. Ahnaou, C. Walsh, N. V. Manyakov, S. A. Youssef, W. H. Drinkenburg

“…Alzheimer’s disease (AD) is a progressive, neurodegenerative disease characterized by loss of synapses and disrupted functional connectivity (FC) across different brain regions. …”
Get full text

Recent advances in nanotechnology for Parkinson’s disease: diagnosis, treatment, and future perspectives by Virendra Kumar Yadav, Seshathiri Dhanasekaran, Nisha Choudhary, Deepak Nathiya, Vishal Thakur, Rachna Gupta, Sheersha Pramanik, Pankaj Kumar, Nishant Gupta, Ashish Patel

“…Parkinson’s disease is a progressive neurodegenerative disease that destroys substantia nigra dopaminergic neurons, causing tremors, bradykinesia, rigidity, and postural instability. …”
Get full text

Catecholaminergic dysfunction drives postural and locomotor deficits in a mouse model of spinal muscular atrophy by John G. Pagiazitis, Nicolas Delestrée, Leonie Sowoidnich, Nandhini Sivakumar, Christian M. Simon, Athanasios Chatzisotiriou, Maria Albani, George Z. Mentis

“…Dopamine and noradrenaline strongly influence locomotion, and their dysregulation initiates the development of motor impairments linked to neurodegenerative disease. However, the precise cellular and circuit mechanisms are not well defined. …”
Get full text

The burden of medical contraindications to corneal donation: Time for review. by Oliver Dorado-Cortez, Sylvain Poinard, Magali Epinat, Fanny Collange, Sandrine Ninotta, Paul Goin, Jean Luc Perrot, Philippe Gain, Graeme Pollock, Gilles Thuret

“…The identification of a neurodegenerative disease was the most frequent, accounting for 16% of the files examined and 29% of CIs. …”
Get full text

The potential of stem cell therapy in Multiple Sclerosis treatment: a review by Sorina Amarculesei, Ava O'Meara Cushen, Cathy Brougham

“…Multiple Sclerosis is an autoimmune and neurodegenerative disease of the central nervous system. There are currently 2.8 million people living with Multiple Sclerosis worldwide, including 9000 people in Ireland, with a prevalence of 193 per 100,000 people. …”
Get full text