It Is All in the Genes: A Story of Unexpected Survival in a 67-Year-Old Male with Metastatic Pancreatic Cancer by Patsy W. P. Lee, Scott W. Strum, Elena Tsvetkova

“…(Tyr2215Thrfs∗14) frameshift mutation and somatic GNAS 2531G>A p.(Arg844His) mutation. …”
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The Role of the IL-20 Subfamily in Glaucoma by Mary K. Wirtz, Kate E. Keller

“…In particular, our lab recently identified a T104M mutation in IL-20 receptor-B (IL-20RB) in primary open angle glaucoma patients from a large pedigree. …”
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Simulation Study of Swarm Intelligence Based on Life Evolution Behavior by Yanmin Liu, Ying Bi, Changling Sui, Yuanfeng Luo, Zhuanzhou Zhang, Rui Liu

“…Additionally, PSO is a random swarm intelligence algorithm with the genetic and sociological property, so we embed the improved mutation and crossover operation to particle swarm optimization (PSO) and designed DNA-PSO algorithm to optimize single and multiobjective optimization problems. …”
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An Improved Feedforward-Robust Algorithm for Active Vibration Control of Helicopter Maneuver Flight by Yifan Qin, Yang Lu, Huiyu Yue

“…To solve the problem of secondary path mutation and external disturbance abrupt changes during helicopter maneuver flight, the previous research proposed a hybrid active vibration control law. …”
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A Rare Case of Erdheim-Chester Disease (Non-Langerhans Cell Histiocytosis) with Concurrent Langerhans Cell Histiocytosis: A Diagnostic and Therapeutic Challenge by Hamza Hashmi, Drew Murray, John Greenwell, Marwan Shaikh, Soumit Basu, Maxwell Krem

“…Patients who have the BRAF V600E mutation are treated first line with vemurafenib. For those without the mutation with symptomatic ECD, conventional or PEGylated interferon alpha is recommended. …”
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Genetic Study In a Pakistani Family Reveals Autosomal Recessive Type of Artemis Deficiency by Saddaf Ayub, Abeerah Zainub, Nida Shafi, Zara Khalid Khan, Lubna Siddique, Syed Irfan Raza

“…The mutation leads to Artemis deficiency T-/B-/NK+ type of SCID. …”
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A new efficient genetic algorithm-Taguchi-based approach for multi-period inventory routing problem by Amin Farahbakhsh, Amir Saman Kheirkhah

“…The algorithm parameters, including crossover and mutation rates, population size, number of iterations, and selection pressure, are fine-tuned using the Taguchi method. …”
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Study on Spatio-temporal Variation Characteristics of Hydro-meteorological Factors in the Source Region of Yellow River by WANG Dong, WU Dongdong, JIE Xiaobai, LI Xuehui

“…The results show that; for the annual precipitation,its rising trend isinsignificant, without significant mutation and with significant periodicity of 30 years;for theannual average temperature,its increasing trend is significant, with strong mutations around 1997and without significant periodicity;for the annual runoff,its decreasing trend is significant,with strong mutations around 1989 and significant periodicity of 30 years; the spatialdistribution difference of annual precipitation and average temperature are significant, withdecreasing trend for spatial distribution difference of annual precipitation and with obviousvariation trend for that of annual average temperature; before 2000, the spatial distributiondifference of annual average temperature was obvious, but that was even after 2000. …”
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Fatal Hypogammaglobulinemia 3 Years after Rituximab in a Patient with Immune Thrombocytopenia: An Underlying Genetic Predisposition? by Jean-François Viallard, Marie Parrens, Frédéric Rieux-Laucat

“…The heterozygous mutation in the FASL gene, not present in the Genome Aggregation Database or ClinVar database, could suggest atypical Autoimmune LymphoProliferative Syndrome and its role in this patient’s immunodepression is discussed. …”
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Coexistence of T-Cell Lymphoblastic Lymphoma and Ichthyosis Vulgaris: A Case Report by Şule Çalışkan Kamış, Begül Yağcı

“…Ichthyosis vulgaris (IV) is an inherited disorder characterized by the scaling of the skin. It is caused by mutations in the filaggrin gene. IV is a reactive skin manifestation that may be associated with malignant hematological disease. …”
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Inactivation of the CMAH gene and deficiency of Neu5Gc play a role in human brain evolution by Yuxin Liu, Jinhong Li, Qicai Liu

“…These missing genes might be the key to the evolution of humans’ unique cognitive skills. An inactivation mutation in CMP-N-acetylneuraminic acid hydroxylase (CMAH) was the result of natural selection. …”
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Risk Stratification and Adjuvant Chemotherapy for High‐Risk Stage IA Lung Adenocarcinoma: The Unmet Needs by Chen Shen, Haoran Liu, Bofei Li, Jiaming Wang, Yiyang Wang, Feichao Bao, Zhitao Gu, Wentao Fang

“…Testing rates for EGFR mutation and ALK fusion among high‐risk patients were only 52.4% and 43.9%, respectively, while mutation rates reached up to 55.7% and 9.4%, respectively. …”
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Unraveling the genetic mysteries of spinal muscular atrophy in Chinese families by Shanshan Gao, Duo Chen, Qianqian Li, Xuechao Zhao, Chen Chen, Lina Liu, Miao Jiang, Zhenhua Zhao, Yanhua Wang, Xiangdong Kong

“…Furthermore, one family demonstrated a compound-heterozygous double mutation, while another carried a type “2 + 0” mutation alongside a point mutation. …”
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Role of Prothrombin and Methylenetetrahydrofolate Reductase Gene Polymorphisms as well as Thrombophilia Markers, as Risk Factors for Unexplained Recurrent Miscarriage: A Case-Contr... by Zeinab Ahmed Abd Elhameed, Omar M Shaaban, Hanan G Abd Elazeem, Azza Abouelfadle, Tarek Farghaly, Ghada Mahran, Mohamed Ismail Seddik

“…MTHFRC677T gene showed C/T mutation in 33.3% of group I and 32.2% of group II, while T/T mutation was detected in 12.8%of group I and 8.9% of the group II. …”
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Protracted Clonal Trajectory of a JAK2 V617F-Positive Myeloproliferative Neoplasm Developing during Long-Term Remission from Acute Myeloid Leukemia by Stephen E. Langabeer, Karl Haslam, Maria Anne Smyth, John Quinn, Philip T. Murphy

“…Alternatively, both malignancies possibly evolved from a common precursor defined by a predisposition mutation with divergent evolution into MPN through acquisition of the JAK2 V617F and AML through acquisition of different mutations. …”
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Differential Analysis of Genetic, Epigenetic, and Cytogenetic Abnormalities in AML by Mirazul Islam, Zahurin Mohamed, Yassen Assenov

“…Combining the methylation and mutation data reveals three distinct patient groups and four clusters of genes. …”
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Motion-Genetic Testing is Useful in the Diagnosis of Nonhereditary Pancreatic Conditions: Arguments for the Motion by David C Whitcomb

“…These mutations, as with those of the SPINK1 (or PSTI) gene, are prevalent in North America; thus, the presence of such a mutation in an asymptomatic person does not confer a high risk of developing pancreatitis. …”
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Relapsing Remitting Multiple Sclerosis in X-Linked Charcot-Marie-Tooth Disease with Central Nervous System Involvement by Georgios Koutsis, Georgia Karadima, Paraskewi Floroskoufi, Maria Raftopoulou, Marios Panas

“…We report a patient with relapsing remitting multiple sclerosis (MS) and X-linked Charcot-Marie-Tooth disease (CMTX), carrying a GJB1 mutation affecting connexin-32 (c.191G>A, p. Cys64Tyr) which was recently reported by our group. …”
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Detecting Communities in Complex Networks Using an Adaptive Genetic Algorithm and Node Similarity-Based Encoding by Sajjad Hesamipour, Mohammad Ali Balafar, Saeed Mousazadeh

“…Besides the fact that the proposed encoding can avoid meaningless mutations or disconnected communities, we show that the new initial population generation function and the new adaptive mutation function can improve the convergence time of the algorithm. …”
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Prediction of Chaotic Time Series Based on BEN-AGA Model by LiYun Su, Fan Yang

“…We design the dynamic crossover probability and mutation probability to control the crossover process and the mutation process, and the optimal parameters are selected through the fitness function to evaluate the chromosome. …”
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