Evolutionary Genomics Provides Insights Into Endangerment and Conservation of a Wild Apple Tree Species, Malus sieversii by Jian Zhang, Fang‐Yuan Zhao, Hong‐Xiang Zhang

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TopoQual polishes circular consensus sequencing data and accurately predicts quality scores by Minindu Weerakoon, Sangjin Lee, Emily Mitchell, Haynes Heaton

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In-silico study of E169G and F242K double mutations in leucine-rich repeats (LRR) polygalacturonase inhibiting protein (PGIP) of Gossypium barbadense and associated defense mechanism against plant pathogens by Sneha Murmu, Mayank Rashmi, Dipak T. Nagrale, Tejasman Kour, Mahender Kumar Singh, Anurag Chaurasia, Santosh Kumar Behera, Raja Shankar, Rajiv Ranjan, Girish Kumar Jha, Shailesh P. Gawande, Neelakanth S. Hiremani, Y. G. Prasad, Sunil Kumar

“…Both wild-type and mutated cotton PGIPs were examined in the interaction with the PG enzyme of a bacterial and fungal pathogen. …”
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Multiple intracerebral hematomas during SEEG recording and intradural hemorrhage after spinal tap: A case report prompting more research on collagen IV gene mutation and oral nicotine consumption as risk factors by Markus Leitinger, Serena Broggi, Mathias Spendel, Gudrun Kalss, Ivan Petrović, Herbert Krainz, Fabio Rossini, Julia Höfler, Andreea Toma, Giorgi Kuchukhidze, Matthias Mauritz, Kai‐Nicolas Poppert, Bernardo Crespo‐Pimentel, Pilar Bosque‐Varela, Anna Pleyers, Patricia Ganger, Dieter Kotzot, Davor Lessel, Christoph J. Griessenauer, Eugen Trinka

“…As collagen mutations were previously described risk factors and smoking in particular worsens the bleeding risk in collagen mutations, further research is warranted to prevent hemorrhages in neurosurgical procedures. …”
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Real‐World Study of EGFR‐TKI Rechallenge With Another TKI After First‐Line Osimertinib Discontinuation in Patients With EGFR‐Mutated Non‐Small Cell Lung Cancer: A Subset Analysis of the Reiwa Study by Kei Sonehara, Kazunari Tateishi, Kiyotaka Yoh, Kazuhiro Usui, Yukio Hosomi, Kazuma Kishi, Go Naka, Kageaki Watanabe, Shu Tamano, Kohei Uemura, Hideo Kunitoh

“…Methods This multicenter prospective observational study enrolled patients with EGFR‐mutated NSCLC who received first‐line osimertinib and another EGFR‐TKI as second‐ or third‐line treatment between September 2018 and August 2020. …”
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Generation and characterization of an isogenic control line by correcting the BAG3 P209L mutation of a human induced pluripotent stem cell (hiPSC) line from a patient with myofibrillar myopathy-6 by Kerstin Filippi, Isabelle Riße, Luke M. Judge, Bruce R. Conklin, Bernd K. Fleischmann, Michael Hesse

“…This function is affected by a point mutation (p.P209L; c.626C>T) in the BAG3 gene, leading to myofibrillar myopathy-6 (MFM6), restrictive cardiomyopathy and polyneuropathy, which manifests as severe skeletal muscle weakness and heart failure. …”
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Ranpo par inflexion ou Nagoya en mutation, recension de Ranpo et Nagoya : modernisme d’une ville de province et paysage originel du roman policier, de Komatsu Shōko by Hirotaka Ichiyanagi

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Adaptive fractional-order Darwinian particle swarm optimization algorithm by Tong GUO, Ju-long LAN, Yu-feng LI, Shi-wen CHEN

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The Olive Oil Monophenolic Secoiridoid Ligstroside Aglycone Suppresses Melanoma Progression by Targeting the BRAF Signaling Pathway by Md Ashiq Mahmud, Abu Bakar Siddique, Afsana Tajmim, Judy Ann King, Khalid A. El Sayed

Subjects: “…<i>BRAF V600E</i> mutation…”
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Multi-Strategy Improved Whale Optimization Algorithm and Its Engineering Applications by Yu Zhou, Zijun Hao

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NPRL2 gene therapy induces effective antitumor immunity in KRAS/STK11 mutant anti-PD1 resistant metastatic non-small cell lung cancer (NSCLC) in a humanized mouse model by Ismail M Meraz, Mourad Majidi, Renduo Song, Feng Meng, Lihui Gao, Qi Wang, Jing Wang, Elizabeth J Shpall, Jack A Roth

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Assessment of various etiological factors for oral squamous cell carcinoma in non-habit patients- a cross sectional case control study by Mudiyayirakkani Muthusamy, Pratibha Ramani, Paramasivam Arumugam, Parthiban Rudrapathy, Boopathi Kangusamy, Vishnu Priya Veeraraghavan, Selvaraj Jayaraman, Balachander Kannan, Anitha Pandi

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New Lung Cancer Panel for High-Throughput Targeted Resequencing by Eun-Hye Kim, Sunghoon Lee, Jongsun Park, Kyusang Lee, Jong Bhak, Byung Chul Kim

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The impact of PD-L1 expression status on the prognosis of ALK-positive lung cancer patients by Li Wang, Yingjun Kong, Yao Zhang, Chuanyong Mu

Subjects: “…ALK gene mutation…”
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Identification of alterations in the nucleotide sequence of the chromatin remodeling gene PBRM1 in clear cell renal cell carcinoma patients by E. A. Klimentova, I. R. Gilyazova, A. A. Izmailov, I. M. Sultanov, M. A. Bermisheva, V. N. Pavlov, E. K. Khusnutdinova

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Genome sequencing enhances the diagnostic yield and expands the genetic landscape of male breast cancer by Wen Wen, Sen Zhao, Yiwen Jiang, Chengzhu Ou, Changyuan Guo, Ziqi Jia, Jiayi Li, Yansong Huang, Hengyi Xu, Pengming Pu, Tongxuan Shang, Lin Cong, Xiang Wang, Nan Wu, Jiaqi Liu

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Heterogeneity of Genetic Landscapes in Salivary Gland Tumors and Their Critical Roles in Current Management by Anam YOUSAF, Sarina SULONG, Baharudin ABDULLAH, Norhafiza Mat LAZIM

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Impact of socio-demographic structure of the deaf people communities in prevalence of hereditary hearing loss by O. L. Posukh, M. S. Bady-Khoo, M. V. Zytsar, V. Yu. Mikhalskaia, S. A. Lashin, N. A. Barashkov, G. P. Romanov

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Spontaneous and environment induced genomic alterations in yeast model by Ke-Jing Li, Lei Qi, Ying-Xuan Zhu, Min He, Qian Xiang, Dao-Qiong Zheng

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Phenotypic and genotypic characterization of Mycobacterium tuberculosis pyrazinamide resistance—India, 2018–2020 by Sembulingam Tamilzhalagan, Evanslin Santus Justin, Ashok Selvaraj, Karthick Venkateswaran, Arun Kumar Sivakumar, Suganthi Chittibabu, Heather P. McLaughlin, Patrick K. Moonan, Jonathan P. Smith, Sakthi Suba, Mukesh Kumar Sathya Narayanan, Christine S. Ho, Nishant Kumar, Srikanth P. Tripathy, Srikanth P. Tripathy, Siva K. Shanmugam, Patricia J. Hall-Eidson, Uma Devi Ranganathan

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