“From in the light I touched the light” by Anne-Laure Tissut

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MASH as an emerging cause of hepatocellular carcinoma: current knowledge and future perspectives by Michael Karin, Ju Youn Kim

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Interactions between key genes and pathways in prostate cancer progression and therapy resistance by Fan Wu, Hengsen Zhang, Miaomiao Hao

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Brain magnetic resonance imaging findings in Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE): A case-based review by Maria Veatriki Christodoulou, MD, MSc, Nikoletta Anagnostou, MD, MSc, Anastasia K. Zikou, MD, PhD

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Genomic Variation in Dengue Virus Non-Structural Protein 5 (NS5). by Saira Mushtaq, Malik Ihsan Ullah Khan, Muhammad Tahir Khan, Aneeqa Shahid, Rameesha Shafiq, Sarwat Jahan

Subjects: “…Dengue virus, Whole Genome Sequencing, mutation, NS5, Pakistan…”
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Dihydrotanshinone I enhanced BRAF mutant melanoma treatment efficacy by inhibiting the STAT3/SOX2 signaling pathway by Xing Luo, Yi Duan, Jinwei He, CongGai Huang, Jun Liu, Yifan Liu, Mengdei Xu, Qiong Dai, Zhihui Yang

Subjects: “…BRAF mutation…”
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Clinical and molecular characteristics and long-term outcomes of pediatric intracranial meningiomas: a comprehensive analysis from a single neurosurgical center by Leihao Ren, Jiaojiao Deng, Hiroaki Wakimoto, Qing Xie, Ye Gong, Lingyang Hua

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Ecological and genetic assessment of the consequences of radiation influence on contaminated areas by A. B. Bigaliev, K. Z. Shalabaeva, B. E. Shimshikov, S. S. Kobegenova, L. M. Adilova, A. N. Kozhakhmetova, S. Sharakhmetov, M. N. Burkhanova

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Phenotype and genetic spectrum of six Indian patients with bestrophinopathy by Areeba Shakeel, Darshan M Bhatt, Lingam Gopal, Rajiv Raman, Chetan Rao, S. Sripriya, Muna Bhende

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APOPTOSIS IN CITY SYSTEMS: A BIOMIMETIC APPROACH TO CITY REGENERATION by Stephen Ajadi

Subjects: “…Apoptosis, Mutations, City Systems, Biomimetics, Settlements…”
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MPN/MDS OVERLAP SYNDROME ANTICIPATED BY A SEVERE BLEEDING DIATHESIS: HYPOTHESIS OF A PRE-EXISTING PLATELET DISORDER by Paola Ranalli, Stefano Baldoni, Daniela Bruno, Mauro Di Ianni

Subjects: “…Myeloid Neoplasms; Germline mutations…”
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HВcorAg expression in HВeАg-negative hepatitis: correlation to clinical and histological activity and HВsAg-status by O. P. Dudanova, I. A. Pravdolyubova

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Knock-In Mice with Myo3a Y137C Mutation Displayed Progressive Hearing Loss and Hair Cell Degeneration in the Inner Ear by Peipei Li, Zongzhuang Wen, Guangkai Zhang, Aizhen Zhang, Xiaolong Fu, Jiangang Gao

“…To investigate the mechanism of DFNB30-type deafness, we established a mouse model of Myo3a kinase domain Y137C mutation by using CRISPR/Cas9 system. No difference in hearing between 2-month-old Myo3a mutant mice and wild-type mice was observed. …”
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Generation of human induced pluripotent stem cell lines from three different male XLRS patients carrying RS1 gene mutation by Sang-Yun Kim, Yong-Min Choi, Yunho Park, Seung-Hyun Kim, Hyun Beom Song, Jeong Hun Kim, Ok-Seon Kwon, Kyung-Sook Chung

“…X-linked retinoschisis (XLRS) is an inherited retinal disease caused by mutation in RS1 gene. Due to limited cell sources available for studying retinal disease, patient-derived induced pluripotent stem cells (iPSCs) offer an essential resource for developing XLRS disease models. …”
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Enjeux de la mutation des techniques artisanales sur la formalisation de l’exploitation de l’or au Burkina Faso by Edith Sawadogo, Dapola Evariste Constant Da†

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Gender and melanoma subtype‐based prognostic implications of MUC16 and TTN co‐occurrent mutations in melanoma: A retrospective multi‐study analysis by Nilesh Kodali, Simona Alomary, Abhijit Bhattaru, Ahmed Eldaboush, Robert A. Schwartz, Shari R. Lipner

“…For MUP patients, only MUC16 mutations correlated with worse prognosis. ALM patients with neither MUC16 nor TTN mutations had significantly more total mutations than MUP patients, followed by CM patients. …”
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The Missing LNK: Evolution from Cytosis to Chronic Myelomonocytic Leukemia in a Patient with Multiple Sclerosis and Germline SH2B3 Mutation by Krishna Gundabolu, Bhavana J. Dave, Carmelita J. Alvares, Jeffrey J. Cannatella, Vijaya R. Bhatt, Lori J. Maness, Zaid S. Al-Kadhimi, Rana K. Zabad, Allison M. Cushman-Vokoun

“…Germline mutation in SH2B adaptor protein 3 (SH2B3) had been reported before to affect a family with autoimmune disorders and acute lymphoblastic leukemia. …”
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High tumor mutational burden assessed through next-generation sequencing predicts favorable survival in microsatellite stable metastatic colon cancer patients by Annabella Di Mauro, Mariachiara Santorsola, Giovanni Savarese, Roberto Sirica, Monica Ianniello, Alessia Maria Cossu, Anna Ceccarelli, Francesco Sabbatino, Marco Bocchetti, Anna Chiara Carratù, Francesca Pentimalli, Gerardo Ferrara, Guglielmo Nasti, Michele Caraglia, Alessandro Ottaiano

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Clinical utility of tumour mutational burden on efficacy of immune checkpoint inhibitors in malignant solid tumours: protocol for a systematic review and meta-analysis by Xiaoguang Yang, Yunming Li, Xuemei Xiang, Wang Guo, Pengfei Zhou

“…We propose a systematic review to evaluate the predictive value of tumour mutation burden (TMB) on efficacy of ICIs.Methods and analysis A systematic literature search will be conducted in the PubMed, OVID, Web of Science, Embase and Cochrane Central Register of Controlled Trials Library databases up to 31 May 2022. …”
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OsHMA3 overexpression works more efficiently in generating low-Cd rice grain than OsNramp5 knockout mutation by Yuejing Gui, Joanne Teo, Dongsheng Tian, Raji Mohan, Zhongchao Yin

“…In this study, we compared the efficiency of OsNramp5 knockout mutation and OsHMA3 overexpression in reducing Cd content in rice grain. …”
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