Paysage millénaire et développement touristique en Chine. Le cas des rizières en terrasses des Hani du Yunnan by Myriam Dao

“…Suite à un travail de terrain entre 1995 et 2015, dans un village de riziculteurs du Sud-Ouest de la Chine, en tant qu’artiste-chercheuse, j’examine dans ce texte les profondes mutations qui traversent les territoires frontaliers ruraux habités par les minorités nationales non-Han et en particulier ceux des Hani de la vallée du fleuve Rouge au Yunnan. …”
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Fortis-lenis vs voiced-voiceless plosives in Welsh by Sabine Asmus, Sylwester Jaworski, Michał Baran

“…In light of research results of theoretical as well as experimental investigations into Welsh, e.g. the vowel-coda length dependence discovered by Asmus and Grawunder (2017), advocated further research into that matter, seeing also that the fortis-lenis distinction establishes a firm link to focal properties of Welsh, such as morpheme-initial consonant mutations (mICM). It was, therefore, decided to look at potential phonetic features that would contribute to the postulated distinction. …”
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A szürke OSINT gyanús? by István Solti

“…Érték: A magyar büntetőjog egyes tényállási elemeinek tanulmányozásával mutat ki olyan elkövetési módokat, amik az információgyűjtés bűntetőjogi minősítését alapozhatják meg. …”
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De la bibliothèque au « Tesseract » : une représentation borgésienne de la littérature dans le film de Christopher Nolan Interstellar (2014)  by Emmanuel Buzay

“…Because it is decisive for understanding the way in which the library, as a memory of the world, rethinks humanity, its mutations, and its limits in a journey through time, the constant represented by the figure of the “book in the film” reveals a double identity which, although based on scientific knowledge, nonetheless reactivates an immemorial imaginary with its mythologies. …”
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Gastric Cancer in Young Adults: A Different Clinical Entity from Carcinogenesis to Prognosis by Jian Li

“…According to molecular classifications, the cancer of most GCYA patients belongs to the genomically stable or microsatellite stable/epithelial-mesenchymal transition subtype, with the common genetic aberrations being mutations in CDH1. What characterizes GCYA are a higher prevalence in females, more aggressive tumor behaviors, diagnosis at advanced stages, fewer comorbidities and being better treatment candidates, and a similar or better survival outcome when compared with older patients. …”
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Matérialité nombreuse et spiritualité sans fond dans Les Soprano by Aymen Gharbi

“…Nous ferons dans ce sens s’interpénétrer esthétique littéraire, narratologie, analyse filmique, histoire et sociologie afin de montrer que l’œuvre est habitée, de manière aussi bien volontaire qu’involontaire, par certaines contradictions multidimensionnelles, inhérentes aux mutations de la civilisation libérale et que l’Abîme/Chaos/Sans-Fond de Cornelius Castoriadis, par sa richesse conceptuelle, peut contribuer à décrire.…”
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Case Report: Diagnosis and treatment of incontinentia pigmenti with central nervous system anomalies in one patient by Yun Li, Junbin Hong, Shangge Xu, Tong Zhou, Xiaolan Xiao, Jinghua Yang, Yiting Chen

“…Molecular genetic testing was conducted to identify IKBKG mutations, and the case was finally diagnosed with incontinentia pigmenti complicated by central nervous system anomalies. …”
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South Africa’s Battle Against COVID-19 Pandemic by Ke Yan Loo, Jodi Woan-Fei Law, Loh Teng Hern Tan, Vengadesh Letchumanan

“…As the country struggles to secure and administer COVID-19 vaccines to its people, the Coronavirus has been rapidly mutating and causing new waves of infections within the nation. …”
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Advanced Melanoma: Updated Results from Ongoing Trials by Egle Ramelyte, Ramon Staeger

“…Following the success of BRAF/MEK inhibitors (BRAF/MEKis) and immune checkpoint inhibitors (ICIs), clinical research is ongoing to improve survival rates, particularly in selected patient subgroups, such as patients with treatment-refractory disease or leptomeningeal involvement. In BRAF-mutated cases with more than one first-line option, treatment sequencing has become increasingly important. …”
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Synonymous Codon Usage Controls Various Molecular Aspects by Eu-Hyun Im, Sun Shim Choi

“…Researchers have recognized synonymous codon usage bias (SCUB) in the genomes of almost all species and have investigated whether SCUB is due to random nucleotide compositional bias or to natural selection of any functional exposure generated by synonymous mutations. One of the most prominent observations on the non-neutrality of synonymous codons is the correlation between SCUB and levels of gene expression, such that highly expressed genes tend to have a higher preference toward so-called optimal codons than lowly expressed genes. …”
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La désobéissance civile aux Etats-Unis contemporains : triomphe incomplet du libéralisme sur la gauche, routine et réactivation par les mouvements sociaux de l’immigration by Mathieu Bonzom

“…Secondly, drawing on examples from the immigrant mobilizations of the 2000 and 2010 decades, with a counterpoint to the Civil Rights Movement of the 1950s and 60s, the article shows how the diversity of civil disobedience practices is structured by cyclical mutations, between routinization and defusing on the one hand, revival and reactivation on the other, where reactivation depends on the taking of certain forms of risk which is then turned against the authorities by drawing on mass mobilization.…”
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Integrated single-cell and bulk transcriptome analysis of R-loop score-based signature with regard to immune microenvironment, lipid metabolism and prognosis in HCC by Long Chen, Houzhi Yang, Xianfu Wei, Xianfu Wei, Jianchao Liu, Xiuxin Han, Chao Zhang, Yongheng Liu, Yan Zhang, Yao Xu, Yiqin Li, Guowen Wang, Jinyan Feng

“…Additionally, we constructed a prognostic risk model consisting of 8 RLRGs related to fatty acid metabolism, which effectively evaluated the prognostic value, status of tumor immune microenvironment, gene mutations, and chemotherapeutic drug sensitivity for HCC patients. …”
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Whole genomic analysis uncovers high genetic diversity of rifampicin-resistant Mycobacterium tuberculosis strains in Botswana by Tuelo Mogashoa, Tuelo Mogashoa, Johannes Loubser, Ontlametse T. Choga, Ontlametse T. Choga, Justice Tresor Ngom, Wonderful T. Choga, Wonderful T. Choga, Mpaphi B. Mbulawa, Tuduetso Molefi, One Stephen, Topo Makhondo, Kedumetse Seru, Patience Motshosi, Boitumelo Zuze, Joseph Makhema, Rosemary M. Musonda, Dimpho Otukile, Chawangwa Modongo, Botshelo T. Kgwaadira, Keabetswe Fane, Simani Gaseitsiwe, Rob M. Warren, Sikhulile Moyo, Sikhulile Moyo, Sikhulile Moyo, Sikhulile Moyo, Anzaan Dippenaar, Elizabeth M. Streicher

“…No bedaquiline and delamanid resistance-associated mutations were detected.ConclusionsThis study highlights the high genetic diversity of M. tb strains, with a predominance of lineage 4 among people with RR-TB in Botswana. …”
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An integrative analysis of ASCL1 in breast cancer and inhibition of ASCL1 increases paclitaxel sensitivity by activating ferroptosis via the CREB1/GPX4 axis by Xiaolu Yang, Xiaolu Yang, Yilun Li, Yilun Li, Yaqi Peng, Yuan Chang, Binglu He, Binglu He, Tianqi Zhang, Tianqi Zhang, Shiyu Zhang, Cuizhi Geng, Yunjiang Liu, Xiaolong Li, Jun Hao, Li Ma

“…Genetic alterations in ASCL1 were assessed through the COSMIC and cBioPortal databases, while the TIMER2.0 database provided insights into the relationship between ASCL1 expression and key gene mutations in BC. The GDSC database was used to examine correlations between ASCL1 levels and sensitivity to standard chemotherapeutic agents. …”
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Clonal hematopoiesis of indeterminate potential is a risk factor of gastric cancer: A Prospective Cohort in UK Biobank study by Zhihui Xi, Huolun Feng, Kunling Chen, Xin Guo, Dandan Zhu, Jiabin Zheng, Yong Li

“…Conclusions and relevance: CHIP is associated with gastric cancer in the elderly and contributes to the positive association between DNM3A and ASXL1 mutations and risk of gastric cancer.…”
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Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes by Sowmiya Palani, Yuka Machida, Julia R. Alvey, Vandana Mishra, Allison L. Welter, Gaofeng Cui, Benoît Bragantini , Maria Victoria Botuyan, Anh T. Q. Cong, Georges Mer, Matthew J. Schellenberg, Yuichi J. Machida

“…Abstract FAM111A, a serine protease, plays roles in DNA replication and antiviral defense. Missense mutations in the catalytic domain cause hyper-autocleavage and are associated with genetic disorders with developmental defects. …”
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Primary Hairy Cell Leukemia/Lymphoma of the Breast: A Case Report and Review of the Literature by Monika Pilichowska, Ahmad Shariftabrizi, Ian Mukand-Cerro, Kenneth Miller

“…Extensive immunohistochemical studies supported by positive BRAF V600E mutational status confirmed the diagnosis of HCL. The patient remains asymptomatic without treatment one year following the diagnosis. …”
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Current Trends in the Molecular Classification of Renal Neoplasms by Andrew N. Young, Viraj A. Master, Mahul B. Amin

“…The primary approach to diagnosis is by light microscopy, using the World Health Organization (WHO) classification system, which defines histopathologic tumor subtypes with distinct clinical behavior and underlying genetic mutations. However, light microscopic diagnosis of RCC subtypes is often difficult due to variable histology. …”
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Mutant glycosidases for labeling sialoglycans with high specificity and affinity by Shuyu Liang, Qi Tang, Xunzi Guo, Zi’an Li, Yilan Guo, Jinghan Chang, Bo Cheng, Qitao Song, Jiayu Sun, Peng Dai, Xing Chen

“…Here we report the development of glycan recombinant affinity binders (GRABs) based on mutant bacterial sialidases, which are enzymatically inactive but preserve stringent specificity for sialoglycan substrates. By mutating a key catalytic residue of Streptococcus pneumoniae neuraminidase A (SpNanA) and Ruminococcus gnavus neuraminidase H (RgNanH), we develop GRAB-Sia and GRAB-Sia3 recognizing total sialoglycans and α2,3-sialosides, respectively. …”
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Interaction of RECQL4 with poly(ADP‐ribose) is critical for the DNA double‐strand break response in human cells by Sunyoung Shin, Dongmin Kim, Hyemi Kim, Won‐Ho Cho, Gyungmin Kim, Joon‐Kyu Lee

“…By replacing this PBM with a PBM of hnRNPA2 or its mutated form, we demonstrated that the PBM in RECQL4 is required for PARylation‐dependent recruitment and the roles of RECQL4 in the DSB response. …”
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