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A Muscle Physiology-Based Framework for Quantifying Training Load in Resistance Exercises
Published 2025-01-01“…This study was aimed to provide a muscle physiology-based approach for quantifying TL in resistance exercises (REs). …”
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Calcium Handling in Airway Smooth Muscle: Mechanisms and Therapeutic Implications
Published 1998-01-01“…Calcium plays a central role in the activation of many cellular processes, including the most relevant end-point in airway smooth muscle physiology: contraction. For this reason, the cytosolic concentration of calcium is tightly controlled by an elaborate array of mechanisms. …”
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Gut Dysbiosis and Muscle Aging: Searching for Novel Targets against Sarcopenia
Published 2018-01-01“…Here, we review the current knowledge of the changes in intestinal microbiota that occur in advanced age with a special emphasis on findings supporting the idea of a modulation of muscle physiology through alterations in gut microbial composition and activity.…”
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Label-free proteomic analysis of Duchenne and Becker muscular dystrophy showed decreased sarcomere proteins and increased ubiquitination-related proteins
Published 2025-01-01“…The human phenotypes most related to the proteomic signature were abnormal circulating metabolites, muscle physiology, and weakness. Quantitative analysis identified significant changes in proteins associated with sarcomere organization and protein ubiquitination, such as myomesin, myozenin, and E3 ubiquitin-protein ligase rififylin, suggesting these as potential therapeutic targets.…”
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A Comprehensive Review on the Effects of Laser Photobiomodulation on Skeletal Muscle Fatigue in Spastic Patients
Published 2021-01-01“…Besides that, a literature review concerning on muscle physiology, fatigue, and LLLT was made. No language filter was applied, and altogether, 689 papers were identified. …”
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Sarcopenic obesity is attenuated by E-syt1 inhibition via improving skeletal muscle mitochondrial function
Published 2025-02-01“…To investigate the regulatory role of E-syt1 in muscle metabolism, we performed in vivo and in vitro experiments through E-syt1 loss- and gain-of-function on muscle physiology. When E-syt1 is overexpressed in vitro, myoblast proliferation, differentiation, mitochondrial respiration, biogenesis, and mitochondrial dynamics are impaired, which were alleviated by the silence of E-syt1. …”
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Genetic analyses identify circulating genes related to brain structures associated with Parkinson’s disease
Published 2025-01-01“…Additionally, 1345 circulating genes causally linked with white matter tract diffusivity were enriched for muscle physiological abnormalities (padj < 0.05). Notable genes, including LRRC37A4P (effect size = 15.7, p = 1.23E-55) and KANSL1-AS1 (effect size = -15.3, p = 1.13E-52), were directly associated with PD. …”
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