Targeting Histone Deacetylases: A Novel Approach in Parkinson’s Disease by Sorabh Sharma, Rajeev Taliyan

“…The worldwide prevalence of movement disorders is increasing day by day. Parkinson’s disease (PD) is the most common movement disorder. …”
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A case report of acute promyelocytic leukemia with myeloid sarcoma of the lumbar spine and literature review by Yiwen Du, Kun Yang, Yantao Ling, Ying Zhang, Yuping Gong

“…This report describes a 53-year-old male who presented with low back pain and a movement disorder in his lower limbs. MRI and PET/CT scans of the lumbar spine revealed an intraspinal mass. …”
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deutetrabenazine for the treatment of chorea associated with Huntington’s disease by Harshit Gupta, Wil Perkins, Cain Stark, Sathya Kikkeri, Juyeon Kakazu, Adam D. Kaye, Alan D. Kaye

“…Huntington’s disease is characterized by a variety of motor, psychiatric, and cognitive symptoms with chorea being one of the more notable ones. Chorea is a movement disorder present in multiple neurologic diseases that causes involuntary and irregular muscle movements theorized to be stemming from high dopamine levels. …”
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Psychiatric and Behavioral Complications of GPi DBS in an Adolescent with Myoclonus Dystonia by Graciela Kriegel, Melanie I. Stuckey

“…Myoclonus dystonia is a rare movement disorder that often causes significant disability. …”
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Focal hand dystonia due to hemorrhage of the cervical spinal mass: a case report by Pelin Analay, Hazal Sevinç, Hilmi Berkan Abacıoğlu, Rahşan Göçmen, Bayram Kaymak, Levent Özçakar

“…Dystonia is a movement disorder characterized by intermittent or sustained muscle contractions that lead to abnormal postures and/or repetitive movements. …”
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Mitochondrial Dysfunction and α-Synuclein Synaptic Pathology in Parkinson’s Disease: Who’s on First? by Michela Zaltieri, Francesca Longhena, Marina Pizzi, Cristina Missale, PierFranco Spano, Arianna Bellucci

“…Parkinson’s disease (PD) is the most common neurodegenerative movement disorder. Its characteristic neuropathological features encompass the loss of dopaminergic neurons of the nigrostriatal system and the presence of Lewy bodies and Lewy neurites. …”
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The Contribution of α-Synuclein Spreading to Parkinson’s Disease Synaptopathy by Francesca Longhena, Gaia Faustini, Cristina Missale, Marina Pizzi, PierFranco Spano, Arianna Bellucci

“…In sporadic PD, the most common age-related neurodegenerative movement disorder, nigrostriatal dopaminergic deficits are responsible for the onset of motor symptoms that have been related to α-synuclein deposition at synaptic sites. …”
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Clinimetrics of the 9- and 19-Item Wearing-Off Questionnaire: A Systematic Review by Carlos E. Mantese, Artur Schumacher-Schuh, Carlos R. M. Rieder

“…A recent review by the Movement Disorder Society suggested the 19-item (WOQ-19) and 9-item (WOQ-9) questionnaires as screening tools for the wearing-off phenomenon. …”
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Collective Expert Perspectives on the Use of Safinamide as Adjunctive Therapy for Parkinson’s Disease: Online-Based Delphi Survey by Atsushi Takeda, Yoshio Tsuboi, Masahiro Nomoto, Hideki Mochizuki, Nobutaka Hattori

“…To summarize opinions on the optimal patient profile and methods of using safinamide in common clinical scenarios, Japanese movement disorder specialists with expertise in PD investigated the perspectives of neurologists and neurosurgeons. …”
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Kinect-Based Exergames Tailored to Parkinson Patients by Ioannis Pachoulakis, Nikolaos Papadopoulos, Anastasia Analyti

“…Parkinson’s disease (PD) is a progressive neurodegenerative movement disorder where motor dysfunction gradually increases. …”
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Rehabilitation of Speech and Swallowing Disorder in a Patient With Severe Brain Injury in the Subacute Phase: A Case Report by Morteza Farazi, Niyayesh Aali, Seyed Majid Akhvan Hejazi

“…Dysarthria is a speech movement disorder caused by damage to the central nervous system. …”
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Insomnia: definition, pathophysiological models, diagnosis, and treatment by E. Sakalauskaitė-Juodeikienė, R. Masaitienė

“…Polysomnography is recommended when other sleep disorders (periodic limb movement disorder, sleep apnea or narcolepsy) are suspected, also for treatment-resistant insomnia. …”
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The Parkinson’s Disease Composite Scale Is Adequately Responsive to Acute Levodopa Challenge by Dávid Pintér, Pablo Martinez-Martin, József Janszky, Norbert Kovács

“…To investigate the correlation between changes in the motor examination part of the Movement Disorder Society-sponsored Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) and the PDCS motor scores during acute levodopa challenge and calculate a cutoff range on the PDCS indicating clinically relevant improvement. …”
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“Does the Response to Morning Medication Predict the ADL-Level of the Day in Parkinson’s Disease?” by Trine Hørmann Thomsen, Troels Wesenberg Kjær, Lene Bastrup Jørgensen, Anita Haahr, Kristian Winge

“…Data collection encompasses measurements from the Parkinson KinetiGraph, and the ADL-limitations are assessed by the Movement Disorder Society Unified Parkinson Disease Rating Scale (MDS-UPDRS) Part II. …”
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The added value of anosmic subtype on motor subtype in Parkinson’s disease: a pilot study by Chia-Yen Lin, Hsiao-Hui Chen, Ching-Heng Lin, Ming-Hong Chang

“…We assessed 157 participants with PD using the University of Pennsylvania Smell Identification Test (UPSIT), Movement Disorder Society-Sponsored Revision of the Unified Parkinson’s Disease Rating Scale (M-UPDRS), Montreal Cognitive Assessment (MoCA), 39-item Parkinson’s Disease Questionnaire Summary Index (PDQ-39 SI), and 99mTc-TRODAT-1 imaging. …”
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Surface Electromyography for the Diagnosis of Tremor Syndrome: A Study of 97 Patients by Kartika Gulati, Sanjay Pandey

“…Background and Objectives: Tremor is one of the most frequent movement disorders encountered in clinical practice with heterogeneous phenomenology and etiology. …”
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SOX5-Null Heterozygous Mutation in a Family with Adult-Onset Hyperkinesia and Behavioral Abnormalities by Michael Zech, Katharina Poustka, Sylvia Boesch, Riccardo Berutti, Tim M. Strom, Wolfgang Grisold, Werner Poewe, Juliane Winkelmann

“…Aged 43 years, our female index patient demonstrated abrupt onset of mixed generalized hyperkinesia, with dystonic and choreiform movements being the most salient features. The movement disorder was accompanied by behavioral problems such as anxiety and mood instability. …”
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Deciphering Parkinson’s Disease through Eye Movements: A Promising Tool for Early Diagnosis in the Face of Cognitive Impairment by Xianglian Liao, Jian Yao, Hongyin Tang, Yilan Xing, Xin Zhao, Daao Nie, Ping Luan, Guihua Li

“…In this article, we review the correlation between cognitive impairment and eye movement disorder in patients with PD.…”
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Treatment of tardive dyskinesia caused by long-term antipsychotic use: case reports and literature review by I. Pabarčiūtė, M. Karnickas

“…Tardive dyskinesia is a movement disorder that begins with exposure to dopamine receptor-blocking agents for at least a few months. …”
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Validation of the Official Slovak Version of the Unified Dyskinesia Rating Scale (UDysRS) by Matej Skorvanek, Michal Minar, Milan Grofik, Katarina Kracunova, Vladimir Han, Frantisek Cibulcik, Jan Necpal, Ladislav Gurcik, Peter Valkovic

“…The Slovak version of the UDysRS was designated as an official non-English translation and can be downloaded from the website of the International Parkinson and Movement Disorder Society.…”
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