Tumor hypoxia evidences the differential regulation of Mdm2-p53 axis by PTEN in tumor derived vs. normal endothelial cells by Kinga Wilkus-Adamczyk, Klaudia Brodaczewska, Claudine Kieda

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E2F1 activates breast stromal fibroblasts and promotes their paracrine pro-carcinogenic effects by Layla A. Al-Kharashi, Falah H. Al-Mohanna, Abdelilah Aboussekhra, Abdelilah Abousekhra

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Reevaluating the Concept of Treating Experimental Tumors with a Mixed Bacterial Vaccine: Coley’s Toxin by C. Maletzki, U. Klier, W. Obst, B. Kreikemeyer, M. Linnebacher

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XCL1-secreting CEA CAR-T cells enhance endogenous CD8+ T cell responses to tumor neoantigens to confer a long-term antitumor immunity by Kun Chen, Fei Zhao, Hong Zhao, Dongmei Wang, Chunfeng Qu, Zhiyuan Wu, Feifei Wang, Xing-Ning Li, Ruochan Zhang, Chentong Xiao, Yuliang Ran

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DAMPs prognostic signature predicts tumor immunotherapy, and identifies immunosuppressive mechanism of pannexin 1 channels in pancreatic ductal adenocarcinoma by Qianxue Wu, Qian Xiao, Qian Xiao, Xin Tang, Liuying Li, Daqiang Song, Yang Zhou, Benhua Li, Benhua Li, Guosheng Ren, Guosheng Ren, Fang Luo

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Predicting immunotherapy efficacy in endometrial cancer: focus on the tumor microenvironment by Liubov A. Tashireva, Irina V. Larionova, Irina V. Larionova, Nikita A. Ermak, Anastasia A. Maltseva, Ekaterina I. Livanos, Anna Yu. Kalinchuk, Marina N. Stakheyeva, Larisa A. Kolomiets

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Cancer phylogenetic tree inference at scale from 1000s of single cell genomes by Salehi, Sohrab, Dorri, Fatemeh, Chern, Kevin, Kabeer, Farhia, Rusk, Nicole, Funnell, Tyler, Williams, Marc J., Lai, Daniel, Andronescu, Mirela, Campbell, Kieran R., McPherson, Andrew, Aparicio, Samuel, Roth, Andrew, Shah, Sohrab P., Bouchard-Côté, Alexandre

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Alternative splicing in the DBD linker region of p63 modulates binding to DNA and iASPP in vitro by Rebecca Lotz, Christian Osterburg, Apirat Chaikuad, Sabrina Weber, Masato Akutsu, Anne Christin Machel, Ulrike Beyer, Jakob Gebel, Frank Löhr, Stefan Knapp, Matthias Dobbelstein, Xin Lu, Volker Dötsch

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Histopathological Characterization and Whole Exome Sequencing of Ectopic Thyroid: Fetal Architecture in a Functional Ectopic Gland from Adult Patient by Rosalinda Yasato Camargo, Cristina Takami Kanamura, Celso Ubirajara Friguglietti, Célia Regina Nogueira, Sonia Iorcansky, Alfio José Tincani, Ana Karina Bezerra, Ester Brust, Fernanda Christtanini Koyama, Anamaria Aranha Camargo, Fernanda Orpinelli R. Rego, Pedro Alexandre Favoretto Galante, Geraldo Medeiros-Neto, Ileana Gabriela Sanchez Rubio

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A cohort-based multi-omics identifies nuclear translocation of eIF5B /PD-L1/CD44 complex as the target to overcome Osimertinib resistance of ARID1A-deficient lung adenocarcinoma by Dantong Sun, Helei Hou, Feiyue Feng, Weizheng Wu, Jingyu Tan, Tongji Xie, Jiayu Liu, Jinsong Wang, Haili Qian, Junling Li, Puyuan Xing

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From Melanocyte to Metastatic Malignant Melanoma by Bizhan Bandarchi, Linglei Ma, Roya Navab, Arun Seth, Golnar Rasty

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Detection of N-Glycolyl GM3 Ganglioside in Neuroectodermal Tumors by Immunohistochemistry: An Attractive Vaccine Target for Aggressive Pediatric Cancer by Alejandra M. Scursoni, Laura Galluzzo, Sandra Camarero, Jessica Lopez, Fabiana Lubieniecki, Claudia Sampor, Valeria I. Segatori, Mariano R. Gabri, Daniel F. Alonso, Guillermo Chantada, María Teresa G. de Dávila

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A sensitive ERK fluorescent probe reveals the significance of minimal EGF-induced transcription by Zhang Weisheng, Jun Nakayama, Yukino Inomata, Shigeki Higashiyama, Toru Hiratsuka

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Retinoblastoma: The Evidence Does Matter by Nadia L. Prigoda-Leea, Diane Rushlowa, Beata Piovesan, Katherine Zhang, Helen Dimaras, Sanja Pajovic, Brenda L. Galliea

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Case Report: Successful treatment of metastatic retinoblastoma with CNS involvement with anti-GD2 immunotherapy, intrathecal topotecan and reduced systemic chemotherapy by Cristina Larrosa, Margarida Simao-Rafael, Noelia Salvador, Juan Pablo Muñoz, Cinzia Lavarino, Guillermo Chantada, Jaume Mora, Jaume Mora

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Chemical catalyst manipulating cancer epigenome and transcription by Yuki Yamanashi, Shinpei Takamaru, Atsushi Okabe, Satoshi Kaito, Yuto Azumaya, Yugo R. Kamimura, Kenzo Yamatsugu, Tomoya Kujirai, Hitoshi Kurumizaka, Atsushi Iwama, Atsushi Kaneda, Shigehiro A. Kawashima, Motomu Kanai

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Loss of Sirtuin 7 impairs cell motility and proliferation and enhances S-phase cell arrest after 5-fluorouracil treatment in head and neck cancer by Marta Halasa, Syeda Afshan, Anna Wawruszak, Agata Borkowska, Klaudia Brodaczewska, Alicja Przybyszewska-Podstawka, Joanna Kalafut, Marzena Baran, Adolfo Rivero-Müller, Andrzej Stepulak, Matthias Nees

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Enabling next-generation engineered TCR-T therapies based on high-throughput TCR discovery from diagnostic tumor biopsies by Thomas Kuilman, Deborah S. Schrikkema, Jules Gadiot, Raquel Gomez-Eerland, Laura Bies, Julia Walker, Robbert M. Spaapen, Hanna Kok, Demi Houg, Milena Viyacheva, Yvonne B. Claassen, Manuel Saornil, Oscar Krijgsman, Bas Stringer, Huiwen Ding, Anou Geleijnse, Anne C. Meinema, Bianca Weissbrich, Melissa Lancee, Carmen G. Engele, Marianna Sabatino, Pei-Ling Chen, Kenneth Y. Tsai, James J. Mulé, Vernon K. Sondak, Jitske van den Bulk, Noel F. de Miranda, Inge Jedema, John G. Haanen, Jeroen W. J. van Heijst, Ton N. Schumacher, Carsten Linnemann, Gavin M. Bendle

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Knockdown of RFC4 inhibits cell proliferation of oral squamous cell carcinoma in vitro and in vivo by Pengyue You, Di Wang, Zheng Liu, Shuzhen Guan, Ning Xiao, Haotian Chen, Xin Zhang, Lichuan Wu, Guizhen Wang, Haitao Dong

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Build the virtual cell with artificial intelligence: a perspective for cancer research by Tao Yang, Yuan-Yi Wang, Fei Ma, Bing-He Xu, Hai-Li Qian

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