Macrocycle Unidirectional Transport Along a Linear Molecule by a Two‐Step Chemical Reaction Sequence by Aldo C. Catalán, Lucio Peña‐Zarate, Ruy Cervantes, Alberto Vela, Jorge Tiburcio

Subjects: “…Molecular machines…”
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Multi-channel learning for integrating structural hierarchies into context-dependent molecular representation by Yue Wan, Jialu Wu, Tingjun Hou, Chang-Yu Hsieh, Xiaowei Jia

“…However, the data scarcity, combined with the highly non-linear causal relationships between physicochemical and biological properties and conventional molecular featurization schemes, complicates the development of robust molecular machine learning models. Self-supervised learning (SSL) has emerged as a popular solution, utilizing large-scale, unannotated molecular data to learn a foundational representation of chemical space that might be advantageous for downstream tasks. …”
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Three-dimensional structure of entire hydrated murine hearts at histological resolution by Jasper Frohn, Frederik Böddeker, Marius Reichardt, Hendrik Bruns, Titus Czajka, Amara Khan, Ludovic Broche, Michael Krisch, Alberto Bravin, Frauke Alves, Jana Zschüntzsch, Tim Salditt

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Distribution of the four type VI secretion systems in Pseudomonas aeruginosa and classification of their core and accessory effectors by Antonia Habich, Verónica Chaves Vargas, Luca A. Robinson, Luke P. Allsopp, Daniel Unterweger

“…Abstract Bacterial type VI secretion systems (T6SSs) are puncturing molecular machines that transport effector proteins to kill microbes, manipulate eukaryotic cells, or facilitate nutrient uptake. …”
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Ribosomes: An Exciting Avenue in Stem Cell Research by Zhenzhen Han, Qi Zhang, Yanbo Zhu, Jingcheng Chen, Wei Li

“…Ribosomes are stable molecular machines that play a role with changes in the levels of RNA during translation. …”
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Single-cell data reveal heterogeneity of investment in ribosomes across a bacterial population by Antrea Pavlou, Eugenio Cinquemani, Corinne Pinel, Nils Giordano, Van Melle-Gateau Mathilde, Irina Mihalcescu, Johannes Geiselmann, Hidde de Jong

“…Our results thus reveal a range of strategies for investing resources in the molecular machines at the heart of cellular self-replication. …”
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Coupling of alternative splicing and alternative polyadenylation by Zhang Xueying, Liu Feiyan, Zhou Yu

“…Here, we first provide a brief overview of the molecular machines involved in splicing and 3′-end processing events, and then review recent studies on the functions and mechanisms of the crosstalk between the two processes. …”
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