Role of autophagy defects and significance of adherent-invasive <i>Escherichia coli</i> in Crohn's disease development by I. V. Mayev, D. N. Andreev, D. V. Rakitina, Yu. P. Baykova

“…To present new data on a role of molecular genetic disorders of innate immunity at Crohn's disease (CD), and to demonstrate the role of adherent-invasive Escherichia coli (AIEC) as the microorganisms potentially involved in CD development.Summary. …”
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Rapid Detection of the mt3243A > G Mutation Using Urine Sediment in Elderly Chinese Type 2 Diabetic Patients by Yinan Zhang, Xiujuan Du, Xinqian Geng, Chen Chu, Huijuan Lu, Yixie Shen, Ruihua Chen, Pingyan Fang, Yanmei Feng, Xiaojie Zhang, Yan Chen, Yanping Zhou, Congrong Wang, Weiping Jia

“…Moreover, detection of mt3243 A > G mutation in urine sediment with high-resolution melting (HRM) curve and pyrosequencing is feasible in molecular genetic diagnosis.…”
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Species identification based on the fecal DNA samples of the Caprinae by Abdurakhim E. Kuchboev, Oybek O. Amirov, Makhamadi B. Abramatov, Bakhtiyor H. Ruziev, Mehmonjon Kh. Egamberdiyev, Rokhatoy R. Karimova

“…The possibility of using non-invasive biological materials in molecular genetic studies of rare bovids is shown, using the example of the markhor and Siberian ibex of Uzbekistan. …”
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Ontologies in bioinformatics and systems biology by N. L. Podkolodnyy, O. A. Podkolodnaya

“…This review summarizes the features of the subject area (bioinformatics, systems biology, and biomedicine), the main motivation for the development of ontologies and the most important examples of ontological modeling and semantic analysis at different levels of the hierarchy of knowledge: the molecular genetic level, cellular level, tissue levels of organs and the body. …”
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Investigation of metabolic features of glioblastoma tissue and the peritumoral environment using targeted metabolomics screening by LC-MS/MS and gene network analysis by N. V. Basov, A. V. Adamovskaya, A. D. Rogachev, E. V. Gaisler, P. S. Demenkov, T. V. Ivanisenko, A. S. Venzel, S. V. Mishinov, V. V. Stupak, S. V. Cheresiz, O. S. Oleshko, E. A. Butikova, A. E. Osechkova, Yu. S. Sotnikova, Y. V. Patrushev, A. S. Pozdnyakov, I. N. Lavrik, V. A. Ivanisenko, A. G. Pokrovsky

“…Using computational systems biology and artificial intelligence methods implemented in a cognitive platform, ANDSystem, molecular genetic regulatory pathways were reconstructed to describe potential mechanisms underlying the dysfunction of sphingolipid metabolism enzymes. …”
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Аpplicability of microsatellite loci designed for cosmopolitan species for the investigation of endemic species: a case study of Silene sendtneri Boiss. by Jasna Hanjalić, Lejla Ušanović, Lejla Lasić, Abdurahim Kalajdžić, Belma Kalamujić Stroil, Adisa Ahmić, Naris Pojskić

“…Previous studies on this endemic species were based on morphology and effects on seed germination after the treatment with salicylic acid. However, no molecular genetic studies have been conducted on this species so far. …”
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Prospects of Using Microbiota Correction Methods in the Treatment of Inflammatory Bowel Disease by A. I. Akinshina, D. V. Smirnova, A. V. Zagainova, V. V. Makarov, S. M. Yudin

“…In recent years, preference has been given to more accurate and faster molecular genetic methods allowing a more detailed study of the key mechanisms by which microbiota affects the intestine in Crohn’s disease (CD) and ulcerative colitis (UC), as well as of the effect of microbial metabolites on their pathogenesis. …”
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PRPF3-Associated Autosomal Dominant Retinitis Pigmentosa and CYP4V2-Associated Bietti’s Crystalline Corneoretinal Dystrophy Coexist in a Multigenerational Chinese Family by Xiaohong Meng, Qiyou Li, Hong Guo, Haiwei Xu, Shiying Li, Zhengqin Yin

“…To characterize the clinical and molecular genetic characteristics of a large, multigenerational Chinese family showing different phenotypes. …”
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Dysmorphic Facial Features and Other Clinical Characteristics in Two Patients with PEX1 Gene Mutations by Mehmet Gunduz, Ozlem Unal

“…Dysmorphic facial features including broad nasal root, low set ears, downward slanting eyes, downward slanting eyebrows, and epichantal folds were common findings in two patients. Molecular genetic analysis indicated homozygous novel IVS1-2A>G mutation in Case I and homozygous p.G843D (c.2528G>A) mutation in Case II in the PEX1 gene. …”
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Ayurvedic Management of Huntington’s Chorea (Tandava Roga): A Case of Rare Genetic Condition by Mrunal Sunil Bole, Sourabh Deshmukh, Trupti Thakre

“…A 50-year-old male patient presented to the Outpatient Department of Kayachikitsa, diagnosed with Huntington’s chorea based on positive family history, molecular genetic analysis, and chief complaints of abnormal involuntary movements. …”
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ANALYSIS OF THE INTERACTIONS OF NEURONAL APOPTOSIS GENES IN THE ASSOCIATIVE GENE NETWORK OF PARKINSON’S DISEASE by M. A. Yankina, O. V. Saik, P. S. Demenkov, E. K. Khusnutdinova, E. I. Rogaev, I. N. Lavrik, V. А. Ivanisenko

“…We previously developed the ANDSystem tool, designed to automatically extract knowledge from scientific publications and reconstruct on this basis associative gene networks describing the molecular genetic mechanisms of biological processes. The aim of this work was prioritization of neuronal apoptosis genes by their involvement in PD pathogenesis, taking into account the structure of the PD associative gene network using ANDSystem. …”
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Study on early inflorescence development in bread wheat (T. aestivum L.) lines with non-standard SCR-morphotype by O. B. Dobrovolskaya, A. A. Krasnikov, K. I. Popova, P. Martinek, N. Watanabe

“…The SCR-lines characterized using light and scanning electron microscopy represent an important genetic resource for further study of the molecular-genetic mechanisms determining plant architecture. …”
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Agr-typing of methicillin-susceptible Staphylococcus aureus (MSSA) isolated from non-human primates by V. A. Kalashnikova

“…The present study is devoted to molecular genetic testing of S. aureus isolated from different biological samples taken from monkeys and is based on typing of agr polymorphic locus which acts as a regulator of pathogenic gene expression. …”
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Exploration of migration directions in different populations of Eothenomys miletus in the Hengduan Mountains of Yunnan Province: a genome-based analysis by Yanfei Cai, Ting Jia, Wanlong Zhu, Wanlong Zhu, Wanlong Zhu

“…Our results indicated that the ALS population is positioned at the base of the phylogenetic tree, and admixture analysis revealed that the ALS population is more closely related to the JC and DQ populations. Integrate the molecular genetic structure, fossil records of E. miletus as well as the results of our research, we inferred that the migration direction of E. miletus may have been from south to north, suggesting that the DQ and JC populations may have originated from the migration of ALS. …”
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Reconstruction of gene regulatory networks from single cell transcriptomic data by M. A. Rybakov, N. A. Omelyanchuk, E. V. Zemlyanskaya

“…Obtaining omics data for individual cells has made it possible to conduct large-scale molecular genetic studies with an extremely high resolution. …”
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Genetic diversity of Tulipa suaveolens Roth populations in Volgograd Province by T. A. Kritskaya, A. S. Kashin

“…In order to work out the strategy of the species’ preservation, evaluation of its intraand interpopulation polymorphism is required.Materials and methods. Molecular-genetic ISSR markers were used to analyze 125 samples from 10 populations of T. suaveolens occurring in Volgograd Province and 4 populations from Saratov Province.Results. …”
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The creation of new aneuploid lines of the cotton (Gossypium hirsutum L.) with identification of chromosomes by translocation and SSR-markers by M. F. Sanamyan, Sh. U. Bobokhujaev, A. X. Makamov, S. G. Achilov, I. Y. Abdurakhmonov

“…The use of monosomic lines significantly increases the effectiveness of molecular-genetic analysis and the development of superior quality breeding lines via substitutions by alien chromosomes. …”
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The Association between Gly460Trp-Polymorphism of Alpha-Adducin 1 Gene (ADD1) and Arterial Hypertension Development in Ukrainian Population by Svitlana Yermolenko, Yaroslav Chumachenko, Viktor Orlovskyi, Irina Moiseyenko, Oleksandr Orlovskyi

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Loeys-Dietz syndrome by Bogumiła Wójcik-Niklewska, Erita Filipek

“…A 6-year-old boy with Loeys-Dietz syndrome, confirmed by molecular genetic testing, presented with high myopia, subluxated lenses, dysmorphic features, and disorders of the osteoarticular and cardiovascular systems. …”
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Acute Myeloid Leukemia with Basophilic Differentiation Transformed from Myelodysplastic Syndrome by Yasuhiro Tanaka, Atsushi Tanaka, Akiko Hashimoto, Kumiko Hayashi, Isaku Shinzato

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