In Vivo Resistance to Ceftolozane/Tazobactam in Pseudomonas aeruginosa Arising by AmpC- and Non-AmpC-Mediated Pathways by Erik Skoglund, Henrietta Abodakpi, Rafael Rios, Lorena Diaz, Elsa De La Cadena, An Q. Dinh, Javier Ardila, William R. Miller, Jose M. Munita, Cesar A. Arias, Vincent H. Tam, Truc T. Tran

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Genetic analyses identify circulating genes related to brain structures associated with Parkinson’s disease by Zhe Han, Yanping Zhu, Zhenhong Xia, Qing Deng, Hongjie He, Quanting Yin, Hui Zhang, Mudan Yuan, Chunhua Yang, Geng Tian, Jia Mi, Fuyi Xu

“…Our study bridges the gap between molecular genetics, neuroimaging, and PD pathology, and suggests novel targets for diagnosis and treatment.…”
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Rare Manifestation of a c.290 C>T, p.Gly97Glu VCP Mutation by Nivedita U. Jerath, Cameron D. Crockett, Steven A. Moore, Michael E. Shy, Conrad C. Weihl, Tsui-Fen Chou, Tiffany Grider, Michael A. Gonzalez, Stephan Zuchner, Andrea Swenson

“…A 60-year-old man who played ice hockey into his 50’s was evaluated by electrodiagnostics, muscle biopsy, and molecular genetics. Results. With long-standing pes cavus and toe walking, our patient developed progressive weakness, cramps, memory loss, and paresthesias at age 52. …”
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DeepDrug as an expert guided and AI driven drug repurposing methodology for selecting the lead combination of drugs for Alzheimer’s disease by Victor O. K. Li, Yang Han, Tushar Kaistha, Qi Zhang, Jocelyn Downey, Illana Gozes, Jacqueline C. K. Lam

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SOX2+ sustentacular cells are stem cells of the postnatal adrenal medulla by Alice Santambrogio, Yasmine Kemkem, Thea L. Willis, Ilona Berger, Maria Eleni Kastriti, Louis Faure, John P. Russell, Emily J. Lodge, Val Yianni, Bence Kövér, Rebecca J. Oakey, Barbara Altieri, Stefan R. Bornstein, Charlotte Steenblock, Igor Adameyko, Cynthia L. Andoniadou

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Dietary Effect of Withania somnifera Root Powder on Growth, Hematobiochemical Parameters, Immunity, and Disease Resistance to Aeromonas hydrophila in Cyprinus carpio by Syed Sikandar Habib, Muhammad Qamar Saeed, Samrah Masud, Osman Sabri Kesbiç, Javed Ahmed Ujan, Cristina Cravana, Salim S. Al-Rejaie, Mohamed Mohany, Francesco Fazio

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A strategy to increase identification of patients with Familial Hypercholesterolemia: Application of the Simon Broome lipid criteria in a large-scale retrospective analysis by James K. Fleming, Renee M. Sullivan, David Alfego, Natalia T. Leach, Tamara J. Richman, Jill Rafalko

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Allele-specific PCR with fluorescently labeled probes: criteria for selecting primers for genotyping by V. A. Devyatkin, A. A. Shklyar, A. Zh. Fursova, Yu. V. Rumyantseva, O. S. Kozhevnikova

“…It makes it possible to distinguish alleles in a genome with high accuracy without additional manipulations with DNA samples or PCR products; hence the popularity of this method in genetic association studies in molecular genetics and medicine. Due to advancements in technologies for the synthesis of oligonucleotides and improvements in techniques for designing primers and probes, we can expect expansion of the possibilities of this approach in terms of the diagnosis of hereditary diseases. …”
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Epigenetic Alterations and an Increased Frequency of Micronuclei in Women with Fibromyalgia by Victoria Menzies, Debra E. Lyon, Kellie J. Archer, Qing Zhou, Jenni Brumelle, Kimberly H. Jones, G. Gao, Timothy P. York, Colleen Jackson-Cook

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Distribution and clinicopathological characteristics of G-CSF expression in tumor cells and stromal cells in upper tract urothelial carcinoma by Go Kobayashi, Yohei Sekino, Hikaru Nakahara, Kohei Kobatake, Keisuke Goto, Tetsutaro Hayashi, Kazuhiro Sentani, Nobuyuki Hinata

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Methylenetetrahydrofolate reductase gene polymorphisms, lipid profiles, and basic renal functional markers as risk for myocardial infarction: A case-control study and haplotype ana... by Perović Svetlana, Vujović Slavica, Kapur-Pojskić Lejla, Garai Nemanja, Šćepanović Anđelka

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HLA-C Alleles and Cytomegalovirus Retinitis in Brazilian Patients with AIDS by Tânia Gisela Biberg-Salum, Maria de Lourdes Veronese Rodrigues, Ana Paula Morais Fernandes, Neifi Hassan Salum Deghaide, Jayter Silva de Paula, Erick C. Castelli, Celso Teixeira Mendes-Junior, Eduardo Antonio Donadi

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Migration of primordial germline cells is negatively regulated by surrounding somatic cells during early embryogenesis in Drosophila melanogaster by N. V. Dorogova, A. S. Khruscheva, Iu. A. Galimova, D. Yu. Oshchepkov, D. E. Maslov, E. D. Shvedkina, K. A. Akhmetova, S. A. Fedorova

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Pre-gestational diabetes in a young woman with a pathogenic INSR missense mutation, p.(Met1180Lys) by Emma L Prehn, Mairéad Crowley, David Fennell, Brendan T Kinsley, Kevin Colclough, Maria M Byrne

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Influence of age, sex, and presence of cleft lip and palate on the quantity and quality of saliva-derived DNA by Lina M. Escobar, Zita Bendahan, Deisy Abril, David Díaz-Baez, Adolfo Paternina, Farith González-Martinez, Ma Clara González-Carrera

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Robust single-nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose tissue remodeling during obesity by Jisun So, Olivia Strobel, Jamie Wann, Kyungchan Kim, Avishek Paul, Dominic J Acri, Luke C Dabin, Jungsu Kim, Gang Peng, Hyun Cheol Roh

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Profiling gene alterations in striatonigral neurons associated with incubation of methamphetamine craving by cholera toxin subunit B-based fluorescence-activated cell sorting by Rachel D. Altshuler, Megan A. M. Burke, Kristine T. Garcia, Kenneth Class, Raffaello Cimbro, Xuan Li, Xuan Li

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Global Gene Expression Profiling in PPAR-γ Agonist-Treated Kidneys in an Orthologous Rat Model of Human Autosomal Recessive Polycystic Kidney Disease by Daisuke Yoshihara, Masanori Kugita, Tamio Yamaguchi, Harold M. Aukema, Hiroki Kurahashi, Miwa Morita, Yoshiyuki Hiki, James P. Calvet, Darren P. Wallace, Takafumi Toyohara, Takaaki Abe, Shizuko Nagao

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Mechanistic insights into Rho/MRTF inhibition-induced apoptotic events and prevention of drug resistance in melanoma: implications for the involvement of pirin by Bardees M. Foda, Bardees M. Foda, Annika E. Baker, Annika E. Baker, Annika E. Baker, Łukasz Joachimiak, Marzena Mazur, Richard R. Neubig, Richard R. Neubig, Richard R. Neubig

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Sociodemographic, Clinical and Genetic Correlates of Aggressive and Auto-Aggressive Behaviour in Alcohol-Dependent Individuals – Preliminary Study by Czarnecki D, Holec EA, Chodkiewicz J, Ziółkowski M, Gorzkiewicz M

“…Damian Czarnecki,1 Elżbieta Anna Holec,2 Jan Chodkiewicz,3 Marcin Ziółkowski,1 Marta Gorzkiewicz4 1Department of Preventive Nursing, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Torun, Poland; 2Department of Nursing, Stanisław Staszic State University of Applied Scences in Piła, Pila, Poland; 3Institute of Psychology, Department of Clinical Psychology and Psychopathology, University of Łodz, Łodz, Poland; 4Department of Molecular Genetics and Justice, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Torun, PolandCorrespondence: Damian Czarnecki, Department of Preventive Nursing, Nicolaus Copernicus University in Torun, Collegium Medicum in Bydgoszcz, ul. …”
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