Biochanin a modulates steroidogenesis and cellular metabolism in human granulosa cells through TAS2Rs activation: a spotlight on ovarian function by Francesca Paola Luongo, Sofia Passaponti, Alesandro Haxhiu, Irene Ortega Baño, Rosetta Ponchia, Giuseppe Morgante, Paola Piomboni, Alice Luddi

“…Conclusion The findings indicate that BCA modulates transcriptional and metabolic processes in GCs through the activation of TAS2Rs, highlighting their role in endocrine regulation. …”
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The Generation and Modulation of Distinct Gamma Oscillations with Local, Horizontal, and Feedback Connections in the Primary Visual Cortex: A Model Study on Large-Scale Networks by Chuanliang Han, Tian Wang, Yujie Wu, Yang Li, Yi Yang, Liang Li, Yizheng Wang, Dajun Xing

“…Surprisingly, we found that HC and FB, the two types of large-scale connections, play very different roles in generating and modulating GAMMA. While both FB and HC modulate a fast gamma oscillation (around 50-60 Hz) generated by FF and RC, HC generates a new GAMMA oscillating around 30 Hz, whose power and peak frequency can also be modulated by FB. …”
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Prioritization of potential pharmacological targets for the development of anti-hepatocarcinoma drugs modulating the extrinsic apoptosis pathway: the reconstruction and analysis of associative gene networks help by P. S. Demenkov, E. A. Antropova, A. V. Adamovskaya, E. I. Mishchenko, T. M. Khlebodarova, T. V. Ivanisenko, N. V. Ivanisenko, A. S. Venzel, I. N. Lavrik, V. A. Ivanisenko

“…In the present study, 13 criteria were proposed for prioritizing potential pharmacological targets for developing anti-hepatocarcinoma drugs modulating the extrinsic apoptosis pathway. The criteria are based on indicators of the structural and functional organization of reconstructed gene networks of hepatocarcinoma, the extrinsic apoptosis pathway, and regulatory pathways of virus-extrinsic apoptosis pathway interaction and aberrant gene methylation-extrinsic apoptosis pathway interaction using ANDSystem. …”
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SwinInsSeg: An Improved SOLOv2 Model Using the Swin Transformer and a Multi-Kernel Attention Module for Ship Instance Segmentation by Rabi Sharma, Muhammad Saqib, Chin-Teng Lin, Michael Blumenstein

“…The study presents SwinInsSeg, an instance segmentation model that combines the Swin transformer and a lightweight MKA module to segment ships accurately and efficiently in maritime surveillance. …”
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Immune cell infiltration and modulation of the blood-brain barrier in a guinea pig model of tuberculosis: Observations without evidence of bacterial dissemination to the brain. by Amanda S Latham, Charlize E Geer, David F Ackart, Kristin N Weninger, Chase C Gross, Brendan K Podell, Randall J Basaraba, Julie A Moreno

“…Following Mtb infection, proteins critical to BBB function, including claudin V and collagen IV, are modulated without evidence of bacterial dissemination to the brain. …”
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Bariatric Surgery as a Molecular Modulator: The Role of FSHR Polymorphisms in Enhancing eNOS Expression and Reproductive Hormone Dynamics in Women with Severe Obesity by Charalampos Voros, Despoina Mavrogianni, Kyriakos Bananis, Alexios Karakasis, Anthi-Maria Papahliou, Vasileios Topalis, Antonia Varthaliti, Raphail Mantzioros, Panagiota Kondili, Menelaos Darlas, Regina Sotiropoulou, Diamantis Athanasiou, Dimitris Mathiopoulos, Panagiotis Antsaklis, Dimitrios Loutradis, Georgios Daskalakis

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The PD-1 with PD-L1 Axis Is Pertinent with the Immune Modulation of Atrial Fibrillation by Regulating T Cell Excitation and Promoting the Secretion of Inflammatory Factors by Guodong Chang, Yingwei Chen, Zichang Liu, Yong Wang, Wenkun Ge, Yongan Kang, Shuling Guo

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IMPLEMENTASI MODUL IPA BERBASIS ETNOSAINS MASYARAKAT BENGKULU MATERI PENGUKURAN MELALUI DISCOVERY LEARNING UNTUK MENINGKATKAN KEMAMPUAN BERPIKIR KRITIS MAHASISWA by Indra Sakti, Aprina Defianti, Nirwana Nirwana

“…Kata kunci: Classroom Action Research, Modul, Etnosains, Discovery Learning, Kemampuan Berpikir Kritis.   …”
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Neuroligin 1 Regulates Autistic‐Like Repetitive Behavior through Modulating the Activity of Striatal D2 Receptor‐Expressing Medium Spiny Neurons by Dandan Lv, An Liu, Ziyue Yi, Mingdao Mu, Miao Wu, Xingcan Li, Kun Cao, Ruining Liu, Zhengping Jia, Junhai Han, Wei Xie

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FINITE ELEMENT STRESS AND STRAIN ANALYSIS OF BGA SOLDER JOINT OF BOARD LEVEL OPTICAL INTERCONNECTION MODULE UNDER TEMPERATURE AND VIBRATION COUPLED CONDITION by HUA JianWei, HUANG ChunYue, LIANG Ying, HUANG Wei, ZHANG Long

“…Based on ANSYS software established board level optical interconnect module finite element model,by means of the analysis of the model of the thermal-structure random vibration coupling,obtained the data of stress and strain under the coupling condition,analyzed the influence of the change of the shape parameters of three kinds of solder joints,the height of the solder joints,the diameter of the pad and the volume of the solder balls.The results show that the stress and strain value of the solder joint is gradually reduced from the center position to the solder joint at both ends;the maximum stress and strain point appeared in the solder joint at the corner of the array.With the increase of the solder joint height,the maximum stress and strain of the solder joint increased gradually.With the increase of the diameter of the pad and the volume of the solder ball,the maximum stress and strain decreased gradually.…”
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Dexmedetomidine Mitigates Microglial Activation Associated with Postoperative Cognitive Dysfunction by Modulating the MicroRNA-103a-3p/VAMP1 Axis by Zhichao Wu, Han Wang, Zuan Shi, Yalan Li

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The Modulation Instability Analysis and Analytical Solutions of the Nonlinear Gross−Pitaevskii Model with Conformable Operator and Riemann Wave Equations via Recently Developed Scheme by Wei Gao, Haci Mehmet Baskonus

“…Strain conditions of the existence are also reported in detail. Finally, modulation instability analysis of the nonlinear GPE is studied in detail.…”
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Immune Modulation Effects of Lactobacillus casei Variety rhamnosus on Enterocytes and Intestinal Stem Cells in a 5-FU-Induced Mucositis Mouse Model by Chun-Yan Yeung, Jen-Shiu Chiang Chiau, Mei-Lien Cheng, Wai-Tao Chan, Szu-Wen Chang, Chuen-Bin Jiang, Hung-Chang Lee

“…Probiotics were shown to modulate the immune response. This is the first study to analyze the immune modulation effects and safety of Lactobacillus strain on enterocytes and intestinal stem cells in a mouse model.…”
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Solar energy driven photocatalytic membrane modules for water reuse in agricultural and food industries.... by Ignazio Renato Bellobono, Franca Morazzoni, Riccardo Bianchi, Emilia Simona Mangone, Rodica Stanescu, Cristina Costache, Paola Maria Tozzi

“…A membrane module, utilizing photocatalytic membranes, has been employed in a pilot plant, in conditions of solar irradiation, to investigate photomineralisation of atrazine, propazine, terbutylazine, symazine, prometryn, and ametryn, as model molecules of s-triazine herbicides, at a standard concentration (1.0 ppm) simulating those of contaminated aquifers, by using ozone as oxygen supplier. …”
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Modulation of Tyrosine Hydroxylase, Neuropeptide Y, Glutamate, and Substance P in Ganglia and Brain Areas Involved in Cardiovascular Control after Chronic Exposure to Nicotine by Merari F. R. Ferrari, Emerson F. Coelho, Karen L. G. Farizatto, Gerson Chadi, Debora R. Fior-Chadi

“…In summary, nicotine positively modulated the studied variables in ganglia while its central effects were mainly constrained to SHR.…”
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ZBiotics ameliorates T2DM-induced histopathological damage in liver, kidney and adipose tissues by modulating the NOD-like receptor signaling in Wistar rats by Mohammed Esawie, Marwa Matboli, Mariam Sameh Bushra, Amany H. Hasanin, Eman Kamal Habib, Reham Hussein Mohamed, Hebatalla Said Ali

“…Therefore, ZBiotics is speculated to operate by modulating the genetic-epigenetic network linked to inflammatory cGAS-STING and autophagy signaling. …”
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Long non-coding RNAs modulate glutathione metabolism gene expression and tolerance to Pb stress in root tissue of endophyte-infected rice seedling by He-Fei Sun, Xin-Nan Wang, Ya-Nan Li, Lan-Lan Wang, Yue-Ying Li, Lian-Ju Ma, Xue-Mei Li

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Chronic inflammation in post-acute sequelae of COVID-19 modulates gut microbiome: a review of literature on COVID-19 sequelae and gut dysbiosis by Najeeha Talat Iqbal, Hana Khan, Aqsa Khalid, Syed Faisal Mahmood, Nosheen Nasir, Iffat Khanum, Isadora de Siqueira, Wes Van Voorhis

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Photo-curing hyaluronic acid-Janus antibacterial packs as O2 generator precisely modulate the infectious microenvironment for antibiotic-free periodontal therapy by Runxiu Wei, Gaojie Li, Yuying Huang, Linjing Mi, Jiamin Wu, Huan Huang, Na Yin, Yuling Chen, Qiang Yang, Wenjun Zhang, Bingzhi Sun, Ran Sun, Ling Guo, Min Feng

“…In light of their precise elimination of bacterial colonization and modulation of the infectious microenvironment, the H-Janus antibacterial packs show promising therapeutic potential for preventing the recurrence of periodontal pathogens following scaling and root planning.…”
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Antipsychotic Drugs Reverse MK801-Inhibited Cell Migration and F-actin Condensation by Modulating the Rho Signaling Pathway in B35 Cells by Yi-Chyan Chen, Fu-Ming Tsai, Mao-Liang Chen

“…MK801-induced psychotic symptoms and also the Ras homolog family member A (RhoA) expression and cell division control protein 42 (cdc42) mRNA modulation in the rat brain have been investigated. …”
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