Unravelling the interplay of nitrogen nutrition and the Botrytis cinerea pectin lyase BcPNL1 in modulating Arabidopsis thaliana susceptibility by Antoine Davière, Aline Voxeur, Sylvie Jolivet, Luka Lelas, Samantha Vernhettes, Marie-Christine Soulié, Mathilde Fagard

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JUNB O‐GlcNAcylation‐Mediated Promoter Accessibility of Metabolic Genes Modulates Distinct Epithelial Lineage in Pulmonary Fibrosis by Marie‐Therese Bammert, Meshal Ansari, Leoni Haag, Zuhdi Ahmad, Victoria Schröder, Joseph Birch, Diana Santacruz, Werner Rust, Coralie Viollet, Benjamin Strobel, Alec Dick, Florian Gantner, Holger Schlüter, Fidel Ramirez, Muriel Lizé, Matthew J. Thomas, Huy Q. Le

“…Mechanistically, JUNB undergoes O‐linked β‐N‐acetylglucosamine modification (O‐GlcNAcylation), a critical step in modulating pro‐fibrotic responses to chronic injury. …”
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Improving Psychological Well-Being of Prospective Early Childhood Education Teachers: Module Development Using 4D Model by Ulya Rahmanita, Asiyah Asiyah, Nelly Marhayati, Alimni Alimni, Sahib Khatoon

Subjects: “…prospective early childhood education teachers, psychological well-being, module development, work stress…”
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Temperature-Dependent Hydrogen Modulations of Ultra-Scaled a-IGZO Thin Film Transistor Under Gate Bias Stress by Muhammad Aslam, Shu-Wei Chang, Min-Hui Chuang, Yi-Ho Chen, Yao-Jen Lee, Yiming Li

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Encapsulation of a Pediocin PA-1 producer Pediococcus acidilactici and its impact on enhanced survival and gut microbiota modulation by M. Mokrani, A. Elie, C. Jacquot, F. Kiran, M. Urdaci

“…The present study used encapsulation technology to improve bacteriocin-producing Pediococcus acidilactici HM-2 survivability under in vitro gastrointestinal conditions and evaluate its impact in vivo on gastrointestinal transit and gut microbiota modulation. Materials and Methods: Bacteriocin produced by P. acidilactici HM-2 was purified by chromatographic techniques and identified according to its molecular mass and gene sequencing. …”
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Optimal reception of multiple phase shift keying and quadrature amplitude modulation signals with non-coherent processing of harmonic interference by G. V. Kulikov, T. T. Do, A. A. Lelyukh, V. D. Nguyen

Subjects: “…quadrature amplitude modulation…”
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Preventive role of Pastinaca sativa in mitigating metabolic dysfunction-associated steatotic liver disease via modulation of metabolic endotoxemia by Ji-Eun Park, Hye-Bin Lee, Yu Ra Lee, Guijae Yoo, Hee-Kyoung Son, Sang Yoon Choi, Miri Park, Ho-Young Park

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Functional genomic imaging (FGI), a virtual tool for visualization of functional gene expression modules in heterogeneous tumor samples by Xinlei Chen, Youbing Guo, Xiaorong Gu, Danyi Wen

“…FGI uses weighted gene co-expression network analysis (WGCNA), followed by a modified Phenograph clustering algorithm to identify co-expression gene clusters. These gene modules were annotated and projected onto a t-SNE map for visualization. …”
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Arsenic Trioxide in Synergy with Vitamin D Rescues the Defective VDR-PPAR-γ Functional Module of Autophagy in Rheumatoid Arthritis by Weiyan Wang, Chunling Li, Zhiyi Zhang, Yue Zhang

“…For the first time, we report a defective functional module of autophagy comprising the Vitamin D receptor (VDR), PPAR-γ, microtubule-associated protein 1 light-chain 3 (LC3), and p62 which appears in RA synovial fibroblasts. …”
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Modulation of glymphatic system by visual circuit activation alleviates memory impairment and apathy in a mouse model of Alzheimer’s disease by Wen Wu, Yubai Zhao, Xin Cheng, Xiaoru Xie, Yixiu Zeng, Quan Tao, Yishuai Yang, Chuan Xiao, Zhan Zhang, Jiahui Pang, Jian Jin, Hongbo He, Yangyang Lin, Boxing Li, Junxian Ma, Xiaojing Ye, Wei-Jye Lin

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Modulation of the Wound Healing through Noncoding RNA Interplay and GSK-3β/NF-κB Signaling Interaction by Xianyi Wang, Wanqiu Li, Shengdi Lu, Zhongliang Ma

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TRPV4 modulates inflammatory responses and apoptosis in enteric glial cells triggered by Clostridioides difficile toxins A and B by Dvison de Melo Pacífico, Deiziane Viana da Silva Costa, Maria Lucianny Lima Barbosa, Conceição Silva Martins Rebouças, Simone de Goes Simonato, Cirle Alcantara Warren, Maria Luana Gaudencio dos Santos Morais, Renata Ferreira de Carvalho Leitao, Gerly Anne de Castro Brito

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Effect of exercise training on modulating the TH17/TREG imbalance in individuals with severe COPD: A randomized controlled trial by Juliana Tiyaki Ito, Luan Henrique Vasconcelos Alves, Luana de Mendonça Oliveira, Rafaella Fagundes Xavier, Regina Maria Carvalho-Pinto, Iolanda de Fátima Lopes Calvo Tibério, Maria Notomi Sato, Celso R. F. Carvalho, Fernanda Degobbi Tenorio Quirino dos Santos Lopes

“…Exercise training can modulate the immune response in healthy subjects.Objective We aimed to evaluate the effects of exercise training on Th17/Treg responses and the differentiation of Treg phenotypes in individuals with COPD.Methods This randomized controlled trial included 50 individuals with severe or very severe COPD who were allocated to the Exercise or Control groups. …”
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Dopaminergic modulation of propofol-induced activation in VLPO neurons: the role of D1 receptors in sleep-promoting neural circuits by Kun Qian, Kun Qian, Yu Zhang, Yang Liu, Sisi Wu, Zikun Duan, Jianhao Liao, Jianhao Liao, Wei Luo, Mo Zhou, Xuejiao Dou, Xingkui Liu, Tian Yu

“…Blocking D1 receptors with SCH23390 reversed the effects of DA on PRO-induced changes, while D2 receptor antagonist sulpiride had minimal impact.ConclusionOur findings demonstrate that PRO excites sleep-promoting NA (−) neurons in the VLPO, primarily through GABA_A receptors, with dopaminergic modulation occurring via D1 receptors. These results provide new insights into the neural mechanisms underlying general anesthesia and highlight the potential role of dopaminergic signaling in modulating anesthetic effects on sleep-related neural circuits.…”
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Regulator of G protein signaling-1 facilitates ovarian cancer development by modulating NF-kB signal pathway by Liu Shengnan, Xi Jiayan, Sun Meng, Li Li, Cai Shengyun, Xu Mingjuan

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Influence of target area density parameter and electrostatic pulse width modulation variable nozzle on physical characteristics of precision spray by Lin Zhen, Liang Shengkai, Xie Jinye, Tian Shuo

“…This paper discusses the observation of different precision spraying processes of pulse width modulated variable sprinkler in electrostatic field under different target area densities and discusses the physical characteristics of precision spraying under electrostatic action of different target area density parameters and pulse width modulated variable sprinkler, the influence of various parameters of precision spraying on spray settling rate. …”
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Dietary steviol glycosides mixture supplementation modulates the gene expression of gut chemoreceptors and enhances the antioxidant capacity in weaned piglets by Yunxia Xiong, Zhentao He, Qiwen Wu, Hao Xiao, Shuting Cao, Xuefen Yang, Yajing Li, Zongyong Jiang, Cui Zhu, Li Wang

“…Conclusions Therefore, our results suggest that dietary 100 ~ 150 mg/kg SGs mixture supplementation modulates gene expression of sweet taste recognition receptors and glucose transporters, while also enhancing the antioxidant capacity of weaned piglets.…”
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Acute Psychological Stress Modulates the Expression of Enzymes Involved in the Kynurenine Pathway throughout Corticolimbic Circuits in Adult Male Rats by Haley A. Vecchiarelli, Chaitanya P. Gandhi, Matthew N. Hill

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Modulation of Second Messenger Signaling in the Brain Through PDE4 and PDE5 Inhibition: Therapeutic Implications for Neurological Disorders by Min Kyu Park, Hyun Wook Yang, Seo Young Woo, Dong Yeon Kim, Dae-Soon Son, Bo Young Choi, Sang Won Suh

“…PDE4 and PDE5 are promising therapeutic targets for neurological disorders. Pharmacological modulation of these enzymes offers potential to enhance cognitive function and mitigate pathological mechanisms underlying brain injuries, neurodegenerative diseases, and psychiatric disorders. …”
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Protective Effect of Rosmarinic Acid on Endotoxin-Induced Neuronal Damage Through Modulating GRP78/PERK/MANF Pathway by Li Q, Zheng JW, Wang ZY, Liao SP, Zhu L, Wang X, Wan LH

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