SILAC-based quantification reveals modulation of the immunopeptidome in BRAF and MEK inhibitor sensitive and resistant melanoma cells by Melissa Bernhardt, Anne Rech, Marion Berthold, Melina Lappe, Jan-Niklas Herbel, Florian Erhard, Annette Paschen, Bastian Schilling, Bastian Schilling, Andreas Schlosser

“…We established a data analysis workflow that integrates the de novo sequencing-based tool Peptide-PRISM for comprehensive HLA peptide identification with MaxQuant for accurate quantification.ResultsWe employed this strategy to explore the modulation of the immunopeptidome upon MAPK pathway inhibition (MAPKi) and to investigate alterations associated with early cellular responses to inhibitor treatment and acquired resistance to MAPKi. …”
Get full text

Regional nutrient emissions and hydrological regime modulate the spatiotemporal patterns of nutrient levels within lake bay by Qiqi Yuan, Zhihui Ren, Ruidong Chen, Qingji Zhang, Jinsong Ma, Lachun Wang

Get full text

Preclinical assessment of splicing modulation therapy for ABCA4 variant c.768G>T in Stargardt disease by Dyah W. Karjosukarso, Femke Bukkems, Lonneke Duijkers, Tomasz Z. Tomkiewicz, Julia Kiefmann, Andrei Sarlea, Sander Bervoets, Irene Vázquez-Domínguez, Laurie L. Molday, Robert S. Molday, Mihai G. Netea, Carel B. Hoyng, Alejandro Garanto, Rob W. J. Collin

Get full text

Simple Proofs for Bochner-Schoenberg-Eberlein and the Bochner-Schoenberg-Eberlein Module Properties on ℓpX,A by Shirin Tavkoli, Rasoul Abazari, Ali Jabbari

“…Additionally, we investigate the BSE module property on Banach ℓpX,A-modules and demonstrate that a Banach space ℓpX,Y serves as a BSE Banach ℓpX,A-module if and only if X is finite and Y represents a BSE Banach A-module.…”
Get full text

Research on High Speed Dry Cutting Technology and Machining Experiment of Small Module Spiral Bevel Gear by Qi Liu, Hua Zhang, Jianjun Yang

Subjects: “…Small module spiral bevel gear…”
Get full text

Pituitary adenylyl cyclase-activating polypeptide modulates the stress response: the involvement of different brain areas and microglia by Anika Singh, Paul Shim, Sadaf Naeem, Shafiqur Rahman, Kabirullah Lutfy

“…Previous research has shown that this peptide/receptor system serves as a modulator of the stress response. In addition to modulating the stress response, this system may also be connected to its emerging role as neuroprotective against hypoxia, ischemia, and neurodegeneration. …”
Get full text

Modulation of Spinal GABAergic Inhibition and Mechanical Hypersensitivity following Chronic Compression of Dorsal Root Ganglion in the Rat by Moon Chul Lee, Taick Sang Nam, Se Jung Jung, Young S. Gwak, Joong Woo Leem

Get full text

Smart Wireless Power Transfer Operated by Time-Modulated Arrays via a Two-Step Procedure by Diego Masotti, Alessandra Costanzo, Vittorio Rizzoli

“…The paper introduces a novel method for agile and precise wireless power transmission operated by a time-modulated array. The unique, almost real-time reconfiguration capability of these arrays is fully exploited by a two-step procedure: first, a two-element time-modulated subarray is used for localization of tagged sensors to be energized; the entire 16-element TMA then provides the power to the detected tags, by exploiting the fundamental and first-sideband harmonic radiation. …”
Get full text

MitoQ Modulates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction via Regulating Nrf2 Signaling by Shengfeng Zhang, Qingniao Zhou, Youcheng Li, Yunli Zhang, Yinmei Wu

Get full text

Titin gene mutations enhance radiotherapy efficacy via modulation of tumour immune microenvironment in rectum adenocarcinoma by Hengchang Liu, Jialiang Liu, Xu Guan, Zhixun Zhao, Pu Cheng, Haipeng Chen, Zheng Jiang, Xishan Wang

Get full text

Material screening for the development of a photovoltaic module using biodegradable materials from renewable raw materials by Pander Matthias, Koepge Ringo, Jaeckel Bengt, Mordvinkin Anton

Subjects: Get full text

Protein Kinase Cα Modulates Estrogen-Receptor-Dependent Transcription and Proliferation in Endometrial Cancer Cells by Alicia M. Thorne, Twila A. Jackson, Van C. Willis, Andrew P. Bradford

“…Evidence suggests that PKCα and estrogen signal transduction pathways functionally interact, to modulate ER-dependent growth and transcription. Thus, PKCα signaling, via PI3K/Akt, may be a critical element of the hyperestrogenic environment and activation of ER that is thought to underlie the development of estrogen-dependent endometrial hyperplasia and malignancy. …”
Get full text

Modulating Perception in Interior Architecture Through Décor: An Eye-Tracking Study of a Living Room Scene by Weronika Wlazły, Agata Bonenberg

“…By integrating décor into the analysis of interior architecture, this study broadens the traditional scope of the field, demonstrating how décor composition can modulate spatial perception using eye-tracking technology. …”
Get full text

Preparation and Sintering Effect in Quartz-Barium Titanate Porous Ceramics and Permeability Modulation Using an Implanted Electrode by Ernesto Suaste Gómez, José de Jesús Agustín Flores Cuautle, Omar Terán Jiménez

Get full text

Modulating the human gut microbiome and health markers through kombucha consumption: a controlled clinical study by Gertrude Ecklu-Mensah, Rachel Miller, Maria Gjerstad Maseng, Vienna Hawes, Denise Hinz, Cheryl Kim, Jack A. Gilbert

Get full text

Identification of a ubiquitin-protein ligase MaUPL6 modulating the response to Fusarium wilt in banana by Yaoyao Li, Jingfang Shi, Yile Huo, Xueyi Xie, Qiaosong Yang, Chunhua Hu, Ou Sheng, Fangcheng Bi, Chunyu Li, Ganjun Yi, Wei Wei, Tongxin Dou

Get full text

Automatic Calibration Using a Modified Genetic Algorithm for Millimeter-Wave Antenna Modules in MIMO Systems by Cheng-Nan Hu, Philip Lo, Chien-Peng Ho, Dau-Chyrh Chang

“…To calibrate the massive mm-wave MIMO antenna module, we propose a modified genetic algorithm to align the amplitude/phase of the transmitting/receiving signal of the module to reduce the time required for the calibration process. …”
Get full text

Editorial: Role of epigenetic modulations and transcription factor in cardiovascular disease and coronary artery spasm: mechanisms and interventions by Ioanna Koniari, Nicholas G. Kounis, Ming-Yow Hung, Ming-Yow Hung, Ming-Yow Hung

Get full text

OK-432 Acts as Adjuvant to Modulate T Helper 2 Inflammatory Responses in a Murine Model of Asthma by Cheng-Jang Wu, Pin-Hsun Tseng, Cheng-Chi Chan, Sara Quon, Li-Chen Chen, Ming-Ling Kuo

Get full text

Computational studies and structural insights for discovery of potential natural aromatase modulators for hormone-dependent breast cancer by Snehal Aditya Arvindekar, Sanket Rathod, Prafulla Balkrishna Choudhari, Pradnya Kiran Mane, Aditya Umesh Arvindekar, Suraj Narayan Mali, Bapu Thorat

“…Conclusion: The results presented 23 hit compounds that can be developed as anti-breast cancer modulating agents in the near future. Additionally, anthraquinone compounds with minor structural modification can also serve to be potential aromatase inhibitors. …”
Get full text