The effect of KUS121, a novel VCP modulator, against ischemic injury in random pattern flaps. by Koichi Yoshimoto, Ryosuke Ikeguchi, Takashi Noguchi, Maki Ando, Daichi Sakamoto, Terunobu Iwai, Kohei Nishitani, Hanako Ohashi Ikeda, Akira Kakizuka, Shuichi Matsuda

“…The purpose of this study was to evaluate the effect of KUS121, a VCP modulator, on flap ischemia using a rodent model. 26 Sprague-Dawley rats were randomly divided into two groups. …”
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Unraveling cerebroprotective potential of fenchone: A combined in vivo and in silico exploration of nitric oxide synthase modulation by Bangaru Mamatha, Anka Rao Areti, DSNBK Prasanth, Narender Malothu

“…Abstract In this study, we investigated the cerebroprotective effects of fenchone (FEN) against brain ischemia through in silico and in vivo approaches, focusing on the inhibition of nitric oxide synthase (NOS) and the modulation of oxidative stress markers. Molecular docking revealed the potential binding affinity of FEN for the NOS active site, with a binding energy of -6.6 kcal/mol. …”
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The role of Ashwagandha in modulating gut parameters in dogs—a randomized double-blind placebo-controlled trial by Kala Kumar Bharani, Ashok Kumar Devarasetti, Rajendar Bobbili, Amit Khurana, Donga Durga Veera Hanuman, Roupesh Gudepu, Swapna Guda

“…In addition, the levels of L-citrulline were significantly modulated by ARE intervention, whereas the intervention did not affect intestinal-type alkaline phosphatase (I-ALP), lactate, and carbamoyl-phosphate synthase (CPS). …”
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High-Performance Dielectric Modulated Epitaxial Tunnel Layer Tunnel FET for Label-Free Detection of Biomolecules by Kunal Aggarwal, Avinash Lahgere

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Blockade of ICAM-1 Improves the Outcome of Polymicrobial Sepsis via Modulating Neutrophil Migration and Reversing Immunosuppression by Yan-jun Zhao, Wen-jing Yi, Xiao-jian Wan, Jun Wang, Tian-zhu Tao, Jin-bao Li, Jia-feng Wang, Xiao-ming Deng

“…The rationale may include the modulated neutrophil migration and the reversed immunosuppression.…”
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Orlistat ameliorates lipid dysmetabolism in high-fat diet-induced mice via gut microbiota modulation by Chengyan Huang, Yuanhui He, Ping Chai, Zongxin Liu, Sirui Su, Yanhui Zhang, Yuelan Luo, Shuiping Fu

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Alternative splicing in the DBD linker region of p63 modulates binding to DNA and iASPP in vitro by Rebecca Lotz, Christian Osterburg, Apirat Chaikuad, Sabrina Weber, Masato Akutsu, Anne Christin Machel, Ulrike Beyer, Jakob Gebel, Frank Löhr, Stefan Knapp, Matthias Dobbelstein, Xin Lu, Volker Dötsch

“…The ASPP family of proteins is involved in modulating the transcriptional activity of the p53 protein family members, including p63. …”
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Corrigendum to “Modulation of Short-Chain Fatty Acids as Potential Therapy Method for Type 2 Diabetes Mellitus” by Ruiqi Tang, Lanjuan Li

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Multi-Channel Packet-Analysis System Based on IEEE 802.15.4 Packet-Capturing Modules by Seong-eun Yoo, Poh Kit Chong, Jeonghwan Bae, Tae-Soo Kim, Hiecheol Kim, Joonhyuk Yoo

“…Wireless packets are detected and timestamped by each sniffer module in the MPAS for each channel, and packets are preprocessed and transmitted to a GUI-based analyzer, which then parses the received packets and shows them in order. …”
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Intrathecal Resiniferatoxin Modulates TRPV1 in DRG Neurons and Reduces TNF-Induced Pain-Related Behavior by M. Leo, M. Schulte, L.-I. Schmitt, M. Schäfers, C. Kleinschnitz, T. Hagenacker

“…Previous studies suggest interactions between tumor necrosis factor- (TNF-) alpha and TRPV1, resulting in a modulation of ion channel function and protein expression in sensory neurons. …”
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Gut microbiota modulation in cardiac cell therapy with immunosuppression in a nonhuman primate ischemia/reperfusion model by Hung-Chih Chen, Yu-Che Cheng, Marvin L. Hsieh, Po-Ju Lin, Emily F. Wissel, Theodore Steward, Cindy M. C. Chang, Jennifer Coonen, Timothy A. Hacker, Timothy J. Kamp, Patrick C. H. Hsieh

“…The interplay between shift in microbial community and host homeostasis during treatment suggests gut microbiome modulation could improve cell therapy outcomes.…”
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Epsin3 promotes non-small cell lung cancer progression via modulating EGFR stability by Huiling Su, Jie Shen, Chenzi Gao, Yue Zhao, Wanyu Deng, Bo Qin, Xin Zhang, Juan Lai, Qian Wang, Jie Dou, Min Guo

“…In this study, we aimed to investigate the role of EPN3 in modulating EGFR function, its effects on NSCLC progression, and its potential involvement in tyrosine kinase inhibitor (TKI) resistance, which remains a significant hurdle in NSCLC treatment. …”
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A Two-Level Iterative Node Importance Evaluation of Aircraft Function Modules Based on Influence Matrix by Chang Liu, Jinyan Wang, Kangxing Wang

“…In view of this situation, this paper researches the two-level iterative method of evaluating the importance of aircraft function modules. The influence matrix was constructed by using the node access probability calculated by the PageRank algorithm and the function module weight calculated based on centrality. …”
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Impact of power ultrasound on the quality of leafy green produce through a multifrequency, multimode, modulated system by Bin Zhou, J. Atilio de Frias, Yaguang Luo, Jorge M. Fonseca, Hao Feng

“…The present study examined the response of leafy greens to ultrasound treatment as shown by tissue damage and sensory quality, using a novel multifrequency, multimode, modulated (MMM) system to address the issue of nonuniform ultrasound field distribution. …”
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Modulation de l’expression vocale des primates en fonction des contraintes socio-écologiques by Jean‑Pierre Gautier

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Enhancing Photovoltaic Module Fault Diagnosis with Unmanned Aerial Vehicles and Deep Learning-Based Image Analysis by J. Jerome Vasanth, S. Naveen Venkatesh, V. Sugumaran, Vetri Selvi Mahamuni

“…Six test conditions of PV modules such as good panel, snail trail, delamination, glass breakage, discoloration, and burn marks were considered in the study. …”
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Temperature Regulation of Photovoltaic Module Using Phase Change Material: A Numerical Analysis and Experimental Investigation by Hasan Mahamudul, Md. Momtazur Rahman, H. S. C. Metselaar, Saad Mekhilef, S. A. Shezan, Rana Sohel, Sayuti Bin Abu Karim, Wan Nur Izzati Badiuzaman

“…This work represents an effective design of a temperature regulated PV module by integrating phase change materials for Malaysian weather condition. …”
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Leucine Modulates Mitochondrial Biogenesis and SIRT1-AMPK Signaling in C2C12 Myotubes by Chunzi Liang, Benjamin J. Curry, Patricia L. Brown, Michael B. Zemel

“…Thus, C2C12 myotubes were treated with leucine (0.5 mM), alanine (0.5 mM), valine (0.5 mM), EX527 (SIRT1 inhibitor, 25 μM), and Compound C (AMPK inhibitor, 25 μM) alone or in combination to determine the roles of AMPK and SIRT1 in leucine-modulation of energy metabolism. Leucine significantly increased mitochondrial content, mitochondrial biogenesis-related genes expression, fatty acid oxidation, SIRT1 activity and gene expression, and AMPK phosphorylation in C2C12 myotubes compared to the controls, while EX527 and Compound C markedly attenuated these effects. …”
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Blast‐Overpressure Induced Modulation of PARP‐SIRT‐NRF2 Axis in Stress Signaling of Astrocytes and Microglia by Vijaya Prakash Krishnan Muthaiah, Kathiravan Kaliyappan, Ramkumar Thiayagarajan, Supriya Mahajan, Krishnamoorthy Gunasekaran

“…Objective The objective is to determine the downstream modulation of the PARP‐SIRT‐NRF2 axis and changes in ATP levels following blast exposure in astrocytes and microglia cell lines. …”
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Alpha-1 Antitrypsin as a Regulatory Protease Inhibitor Modulating Inflammation and Shaping the Tumor Microenvironment in Cancer by Siyu Xiang, Liu Yang, Yun He, Feng Ding, Shuangying Qiao, Zonghua Su, Zheng Chen, Aiping Lu, Fangfei Li

“…However, the lack of comprehensive reviews in this field hinders our understanding of AAT as an essential immune modulator with great potential in cancer immunotherapy. …”
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