FORMATION OF STUDENTS’ SCIENTIFIC THINKING BASED ON THE LEARNING OF METHODS OF THE SUBSTANCE ANALYSIS by M. A. Kosareva, L. A. Baikova, E. A. Nikonenko, V. V. Vaitner, A. N. Gabdullin

“…The materials presented in the article can assist in designing the curricula of chemical disciplines or modules of educational programs.…”
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MTMR6 downregulation contributes to cisplatin resistance in oral squamous cell carcinoma by Kah Young Lee, Su Young Oh, Heon-Jin Lee, Tae-Geon Kwon, Jin-Wook Kim, Chang-Geol Shin, Su-Hyung Hong, So-Young Choi

“…Functional analyses revealed that modulating MTMR6 activity alters cisplatin resistance. …”
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Refinement of the co-content function, through an integration of a polynomial fit of $$I-{I}_{sc}$$ I - I sc . Part 1 theoretical analysis and proposal by Victor-Tapio Rangel-Kuoppa

“…The methodology proposed in this article is appliable to unevenly/randomly distributed IV data points, and it is implemented in Part 2 in solar cells’ and photovoltaic modules’ experimental $$IV$$ IV reported in the literature, to deduce their five solar cell parameters.…”
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Exercise medicine as adjunct therapy during RADIation for CAncer of the prostaTE to improve treatment efficacy – protocol for the ERADICATE study: a phase II randomised controlled... by Oliver Schumacher, Robert U. Newton, Colin Tang, Raphael Chee, Sjoerd B. Vos, Ronny S. Low, David Joseph, Dennis R. Taaffe, Daniel A. Galvão

“…Emerging research in preclinical animal models indicates that exercise has the potential to enhance the efficacy of cancer treatment by modulating tumour perfusion and reducing hypoxia; however, evidence from randomised controlled trials is currently lacking. …”
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Analysis of mRNA Pentatricopeptide Repeat Domain 1 as a prospective oncogene in clear cell renal cell carcinoma that accelerates tumor cells proliferation and invasion via the Akt/... by Zhongbao Zhou, Yulong Li, Yumeng Chai, Yong Zhang, Pu Yan

“…Abstract Background Although pentatricopeptide repeat domain 1 (PTCD1) has been found to modulate mitochondrial metabolic and oxidative phosphorylation, its contribution in the growth of clear cell renal cell carcinoma (ccRCC) remains unknown. …”
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Investigation into the influence of mild hypothermia on regulating ferroptosis through the P53-SLC7A11/GPX4 signaling pathway in sepsis-induced acute lung injury by Liujun Tao, Jie Xu, Liangyan Jiang, Juntao Hu, Zhanhong Tang

“…Conclusion Mild hypothermia attenuates S-ALI and modulates ferroptosis through the P53-SLC7A11/GPX4 signaling pathway.…”
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Chromium "(VI)" phytoremediation using Azolla pinnata: effects on Vicia faba growth, physiology, cytogenetics, and gene expression profiling by Elham R. S. Soliman, Kareem Moustafa, Mohamed Khamis, Zeinab A. Shedeed

“…Conclusion Azolla exhibits substantial potential for reducing the detrimental effects of chromium stress including oxidative stress on plants. It modulates stress-related gene expression, protects DNA integrity, enhances cell mitosis, and reduces chromosomal damage. …”
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Exploring the potential benefits of areca nut extract in animal production: a review by Zhuying Liu, Zhuying Liu, Xiaolong Wang, Lixin Wen, Lixin Wen

“…This review focuses on the biological activities of areca nut extract, particularly its antioxidant, anti-inflammatory, antiparasitic, antibacterial, and microbiota-modulating effects, which collectively contribute to its potential role as a feed additive for enhancing animal health and performance.Key findings indicate that areca nut extract can promote livestock productivity by accelerating growth, enhancing immune responses, and reducing disease incidence. …”
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Cancer-associated fibroblast-derived COL17A1 promotes gemcitabine resistance and tumorigenesis in pancreatic cancer cells by interacting with ACTN4 by Rongyu Shi, Ning Zhang, Han Li, Hu Zhong, Chengcheng Zhong, Wei Du, Xi Yang

“…Abstract Background Cancer-associated fibroblasts (CAFs) are key components of tumor microenvironment and have been identified to be involved in modulating drug resistance in cancers by secreting molecules. …”
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Preliminary application of a cervical vertebra segmentation method based on Transformer and diffusion model for lateral cephalometric radiographs in orthodontic clinical practice by LIU Yang, WU Mengyi, HU Yao, QI Kun, WANG Yubin, ZHAO Yue, SONG Jinlin

“…The diffusion model and a conditional model based on U-Net were utilized for feature extraction, with a Transformer module introduced to learn the interaction between noise and semantic features. …”
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Effects of on-farm hatching versus hatchery hatching on growth performance, gut development, and intestinal health and function in broiler chickens by Muhammad Zeeshan Akram, Ester Arévalo Sureda, Matthias Corion, Luke Comer, Nadia Everaert

“…In conclusion, although the HOF showed only transient growth advantages, it enhanced mucosal morphology and modulated immunity, indicating improved intestinal health.…”
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Imbalance of Microbacterial Diversity Is Associated with Functional Prognosis of Stroke by Xintong Zhang, Xiangyu Wang, Hong Zhao, Risheng Cao, Yini Dang, Binbin Yu

“…Treatment strategies aimed at modulating the gut microbiota and SCFAs may have the potential to enhance the clinical results of patients.…”
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Alpha EEG Spectral Characteristics in the Parieto-Occipital lobe of Elderly Patients with Chronic Insomnia and Mild Cognitive Impairment by GUO Zhenxing, BAI Linxin, ZHANG Lin, GAO Jiahui, RAO Ting, LIU Zhizhen

“…Moreover, Parieto-Occipital lobe alpha spectral power can modulate cognitive function in this population.…”
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USC-Derived Small Extracellular Vesicles-Functionalized Scaffolds Promote Scarless Vaginal Defect Repair via Delivery of Decorin and DUSP3 Proteins by Xu Y, Li J, Qiu Y, Wu F, Xue Z, Liu B, Fan H, Zhou Y, Wu Q

“…LC‒MS/MS analysis was used to identify candidate upstream proteins in USC-sEVs.Results: In vivo experiments demonstrated that the sEVs-loaded scaffolds promoted scarless healing of vaginal defects in rabbits by modulating collagen deposition, reducing fibrosis, and diminishing inflammation. …”
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Bioequivalence study of fluticasone propionate nebuliser suspensions in healthy Chinese subjects by Feng Cheng, Tao Shen, Fucheng Zhang, Chenghao Lei, Ye Zhu, GuoJun Luo, Dawei Xiao

“…The non-compartment model method (NCA module) of the WinNonlin® software (version 8.3) was used to calculate the pharmacokinetic parameters (Cmax, AUC0-t, AUC0-∞) between the test formulation and the reference formulation were within the predefined range of 80.00% and 125.00%, bioequivalence of both formulations was demonstrated.ResultsThe 90% confidence intervals of the T/R ratio of the geometric mean of Cmax, AUC0-t, and AUC0-∞ for both formulations were 90.24%–112.68%, 96.99%–112.27% and 96.41%–111.59% respectively, which were all within the bioequivalent range of 80%–125%. …”
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Human Primary Monocytes as a Model for in vitro Immunotoxicity Testing: Evaluation of the Regulatory Properties of TiO2 Nanoparticles by Svadlakova T, Kolackova M, Kulich P, Kotoucek J, Rosecka M, Krejsek J, Fiala Z, Andrýs C

“…Despite the required biocompatibility, this interaction can affect intracellular homeostasis and modulate physiological functions, particularly inflammation. …”
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Effects of milk extracellular vesicles from Holstein Friesian and Brown Swiss heat-stressed dairy cows on bovine mammary epithelial cells by S. Castellani, L. Basiricò, A. Maggiolino, C. Lecchi, P. De Palo, U. Bernabucci

“…In vitro results of BME-UV1 cells treated with milk sEV H-HS and B-HS showed an alteration of the cell viability and metabolic activity, by reducing or increasing reactive oxygen species accumulation, and suppressing or increasing the expression of stress-associated genes thereby modulating the response of BME-UV1 according to the animals' thermal condition and the breed. …”
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Application of MRI image segmentation algorithm for brain tumors based on improved YOLO by Tao Yang, Xueqi Lu, Lanlan Yang, Miyang Yang, Jinghui Chen, Hongjia Zhao

“…A series of optimizations were made to the original YOLOv5 algorithm, introducing the Atrous Spatial Pyramid Pooling (ASPP), Convolutional Block Attention Module (CBAM), Coordinate Attention (CA) for structural improvement, resulting in several optimized versions, namely YOLOv5s-ASPP, YOLOv5s-CBAM, YOLOv5s-CA, YOLOv5s-ASPP-CBAM, and YOLOv5s-ASPP-CA. …”
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Application of the Rehabilitation Principle of "GU ZHENG (Bones Integrity) and JIN HE (Muscles Harmony), XING SHEN GONG TIAO (Union of Body and Mind)" in Chronic Musculoskeletal Dy... by WANG Xiangbin, HOU Meijin, GOU Yanyun, XU Yang, LIN Ziling, TAO Jing

“…"XING SHEN GONG TIAO-union of body and mind" refers to the correct control of the nervous system on joint movements, muscle activation and coordination, as well as the good coordination of emotion and cognition with bone integrity and muscles harmony, which reflects the importance of body and mind uniformity in promoting motor control ability to the balance of muscles and bones, so as to achieve "regulating the mind to control the body" and "strengthening the body to modulate the mind". Moreover, TCM rehabilitation therapies, such as traditional exercises, acupuncture and moxibustion, Tuina, etc., all reflect the importance of the balance of muscles and bones, and the body and mind."…”
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Different lysine-to-methionine ratios in a low-protein diet affect the microbiome and metabolome, influencing the jejunal barrier function in Tibetan sheep by Fengshuo Zhang, Zhenling Wu, Yu Zhang, Quyangangmao Su, Kaina Zhu, Xuan Chen, Shengzhen Hou, Linsheng Gui

“…Several genes related to barrier function, such as Occludin and Muc- 2, were upregulated in the LP-L group (p < 0.05), while IL-6 and TNF-α were downregulated (p < 0.05).DiscussionCollectively, our results suggest that the dietary Met/ Lys ratio could affect the jejunal SCFA concentration by modulating the microbial community and regulating metabolism, thereby contributing to jejunal barrier function. …”
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