Mannan-Binding Lectin Suppresses Peptidoglycan-Induced TLR2 Activation and Inflammatory Responses by Fanping Wang, Yanhua Li, Can Yang, Yonghui Mu, Yan Wang, Wei Zhang, Yonghui Yang, Chen Chen, Shijun Song, Zhifa Shen, Wenjun Wang, Junpeng Li, Jingjing Zhai, Kang Guo, Ruili Sun, Lili Yu, Mingyong Wang

“…All these data suggest that MBL could downregulate inflammation by modulating PGN/TLR2 signaling pathways. This study supports an important role for MBL in immune regulation and signaling pathways involved in inflammatory responses.…”
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The therapeutic potential of PX-478 in a murine model of pelvic organ prolapse by Wei-Min Fan, Yu-Qi Yang, Li-Wen Zhang, Xiao-Hui Mei, Ke Sun, Duan-Qing Wu, Ying Yang, Chun-Fang Duan, Jun Ye, Ru-Jun Chen

“…It reduces vaginal length, attenuates fibrosis, and modulates collagen synthesis. Its immunomodulation is evident through reduced M1 and M2 macrophages and suppressed IL-18 secretion.…”
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PROTON RADIATION THERAPY: CLINICAL APPLICATION OPPORTUNITIES AND RESEARCH PROSPECTS by M. V. Zabelin, V. A. Klimanov, J. J. Galyautdinova, A. S. Samoilov, A. O. Lebedev, E. V. Shelyhina

“…The data obtained from experience of use of proton radiation therapy with passively scattered fascicle for cancer therapy of a prostate at an early stage showed the admixed results in comparison with modern methods of radiation therapy with the modulated intensity. In treatment of non-small cell cancer of mild advantage of proton therapy aren’t absolutely proved yet. …”
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The impact of prolonged blockade of the releasing hormone on alterations in cardiac macrophage polarisation subsequent to quercetin administration in rats by T.A. Voroshylova, V.I. Shepitko, Ye.V. Stetsuk, N.V. Boruta, O.V. Vilkhova, M.V. Rud, G.S. Puzyryov, O.V. Sych, А.A. Miahkokhlib

“…Animals in the experimental group were injected with a solution of triptorelin at a dose of 0.3 mg of active substance per 1 kg of animal weight to modulate central deprivation of luteinising hormone synthesis. …”
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Dietary supplementation of lysozyme can improve growth rate, laying performance, blood biochemistry, and mRNA levels of some related genes in different plumage-colored quails by Ibrahim Elkhaiat, Seham El-Kassas, Karima El-Naggar, Safaa Abdo, Haitham K. Shalaby, Mahmoud M. Azzam, Alessandro Di Cerbo, Mahmoud Alagawany, Reyad Y. Nofal

“…Accompanying LZ-induced modulations in the expression levels of GHR, IGF-1, leptin, CCK, FAS, and ACC genes in both quail varieties were reported. …”
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The Beneficial Application of Turmeric (Curcuma longa L.) on Health and Egg Production, in Layers: A Review by Saade Abdalkareem Jasim, Aiman Mohammed Baqir Al‐Dhalimy, Maryam Zokaei, Shadi Salimi, Mohammed Jawad Alnajar, Abhinav Kumar, Enas R. Alwaily, Ahmed Hussein Zwamel, Soura Alaa Hussein, Majid Gholami‐Ahangaran

“…It has also been shown to have positive effects on gut health by modulating the gut microbiota composition, improving nutrient absorption and reducing digestive disorders. …”
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In Vitro Effect of Estradiol and Progesterone on Ovine Amniotic Epithelial Cells by Annunziata Mauro, Hashimita Sanyal, Angelo Canciello, Paolo Berardinelli, Valentina Russo, Nicola Bernabò, Luca Valbonetti, Barbara Barboni

“…In conclusion, media supplementation with high doses of steroids may be adopted to modulate phenotype and plasticity during oAEC amplification. …”
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First demonstration of a TES based cryogenic Li $$_2$$ 2 MoO $$_4$$ 4 detector for neutrinoless double beta decay search by G. Bratrud, C. L. Chang, R. Chen, E. Cudmore, E. Figueroa-Feliciano, Z. Hong, K. T. Kennard, S. Lewis, M. Lisovenko, L. O. Mateo, V. Novati, V. Novosad, E. Oliveri, R. Ren, J. A. Scarpaci, B. Schmidt, G. Wang, L. Winslow, V. G. Yefremenko, J. Zhang, D. Baxter, M. Hollister, C. James, P. Lukens, D. J. Temples

“…The largest planned detector array, CUPID, is comprised of about 1500 individual Li $$_{2}$$ 2 $$^{100}$$ 100 MoO $$_4$$ 4 detector modules with a further scale up envisioned for a follow up experiment (CUPID-1T). …”
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Surface water and flood-based agricultural systems: Mapping and modelling long-term variability in the Senegal river floodplain by Andrew Ogilvie, Cheickh Sadibou Fall, Ansoumana Bodian, Didier Martin, Laurent Bruckmann, Djiby Dia, Issa Leye, Papa Malick Ndiaye, Donissongou Dimitri Soro, Jean Homian Danumah, Jean-Claude Bader, Jean-Christophe Poussin

“…Results reveal extreme interannual variations in peak flooded areas, ranging from 30,000 ha and 720,000 ha between 1950 and 2022, while annual water modules fluctuate between 210 and 1460 m3/s. After 1994, flooded areas show partial recovery, with 95th percentile reaching 89,000 ha during 1994–2022 compared to 37,000 ha in 1972–1993. …”
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Brain radiotherapy and dorsal vagal complex irradiation: A new organ at risk to decrease radiation-induced nausea and vomiting? by Valentine Caspar, Nicolas Giraud, Thomas Charleux, Arnaud Beddok, Brieuc Bernard, Maelle Martin, Juliette Thariat, Aymeri Huchet, Véronique Vendrely, Charles Dupin

“…Material: Details of consecutive patients treated for benign brain tumors at the Bordeaux University Hospital using normofractionated intensity modulated radiotherapy technique, without chemotherapy, were accessed. …”
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Optimal multiobjective design of an autonomous hybrid renewable energy system in the Adrar Region, Algeria by Abderrahmane Mehallou, Benalia M’hamdi, Abderrahmane Amari, Madjid Teguar, Abdelaziz Rabehi, Mawloud Guermoui, Amal H. Alharbi, El-Sayed M. El-kenawy, Doaa Sami Khafaga

“…The system is composed of photovoltaic (PV) modules and a wind turbine, a set of batteries as an energy storage unit, a diesel generator as a backup energy source, and an inverter. …”
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PMAIP1 regulates the progression of follicular thyroid carcinoma through the Wnt3/FOSL1 pathway by Haobo Wang, Fangjian Shang, Yifang Wang, Bo Pang, Bo Pang, Longfei Kang, Longfei Kang, Chuanmin Zhou, Chuanmin Zhou, Dongyun Li, Dongyun Li, Zhongxin Li, Zhongxin Li, Xia Jiang, Xia Jiang, Bo Liu, Zengren Zhao

“…Mechanistically, PMAIP1 regulated FOSL1 by modulating the Wnt signaling pathway, thereby promoting FTC progression. …”
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Metabolic reprogramming and immunological changes in the microenvironment of esophageal cancer: future directions and prospects by Zhi-Xun Guo, Jia-Li Ma, Jin-Qiu Zhang, Ling-Ling Yan, Ying Zhou, Xin-li Mao, Xin-li Mao, Xin-li Mao, Shao-Wei Li, Shao-Wei Li, Shao-Wei Li, Xian-Bin Zhou, Xian-Bin Zhou, Xian-Bin Zhou

“…Mounting evidence underscores the importance of modulating metabolic traits within the tumor microenvironment (TME) to augment anti-tumor immunotherapy.MethodsWe selected relevant studies on the metabolism of the esophageal cancer tumor microenvironment and immune cells based on our searches of MEDLINE and PubMed, focusing on screening experimental articles and reviews related to glucose metabolism, amino acid metabolism, and lipid metabolism, as well their interactions with tumor cells and immune cells, published within the last five years. …”
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Cardiac and respiratory activities induce temporal changes in cerebral blood volume, balanced by a mirror CSF volume displacement in the spinal canal by Pan Liu, Kimi Owashi, Heimiri Monnier, Serge Metanbou, Cyrille Capel, Olivier Balédent

“…This study investigates whether cerebral blood volume displacement (CBV), modulated by breathing and cardiac activity, is the predominant drivers of CSF oscillations. …”
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The novel manualized RELIEVE-group treatment for burdened relatives of cancer patients: a feasibility study by Jessica Neumann, Jessica Neumann, Jil Beckord, Jil Beckord, Helen Samira Hesse, Helen Samira Hesse, Carl Martin, Carl Martin, Carlotta Mons, Carlotta Mons, Diana Chur, Diana Chur, Jörg Hense, Jörg Hense, Mitra Tewes, Martin Teufel, Martin Teufel, Eva-Maria Skoda, Eva-Maria Skoda

“…A total of 33 relatives of cancer patients were recruited from the West German Tumor Center and participated in the five modules of the RELIEVE treatment which included an introduction, communication skills, stress and anxiety management and self-care. …”
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Influence of forage-to-concentrate ratio on the effects of a radiata pine bark extract on methane production and fermentation using the rumen simulation technique by N. Vera, S. Suescun-Ospina, C. Gutiérrez-Gómez, P. Williams, C. Fuentealba, R. Allende, J. Ávila-Stagno

“…Hence, the incorporation of radiata PBE into HF diets could serve as an environmentally friendly additive, potentially offering an alternative use for a forestry industry by-product, while beneficially modulating ruminal fermentation.…”
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The short-chain fatty acid receptors Gpr41/43 regulate bone mass by promoting adipogenic differentiation of mesenchymal stem cells by Friederike Behler-Janbeck, Anke Baranowsky, Timur A. Yorgan, Michelle Y. Jaeckstein, Anna Worthmann, Marceline M. Fuh, Karthikeyan Gunasekaran, Gisa Tiegs, Michael Amling, Thorsten Schinke, Joerg Heeren

“…Overall, these data indicate that acetate regulates bone architecture via SCFA-Gpr41/43 signaling by modulating the osteogenic versus adipogenic differentiation of mesenchymal stem cells.…”
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Unlocking melanoma Suppression: Insights from Plasma-Induced potent miRNAs through PI3K-AKT-ZEB1 axis by Pradeep Bhartiya, Apurva Jaiswal, Manorma Negi, Neha Kaushik, Eun Ha Choi, Nagendra Kumar Kaushik

“…Results: NTP exposure for 3 min was sufficient to modulate the expression of several miRNAs, inhibiting cell growth. …”
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Identification and preliminary validation of biomarkers associated with mitochondrial and programmed cell death in pre-eclampsia by Rong Lin, Rong Lin, XiaoYing Weng, XiaoYing Weng, Liang Lin, Liang Lin, XuYang Hu, XuYang Hu, ZhiYan Liu, ZhiYan Liu, Jing Zheng, Jing Zheng, FenFang Shen, FenFang Shen, Rui Li, Rui Li

“…A regulatory network was informed by biomarker expression and database predictions, in which KCNQ1OT1 modulates ACSF2 expression via hsa-miR-200b-3p. Drug predictions, including clodronic acid, were also proposed. …”
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Effects of dietary Bacillus subtilis 14823 on growth performance, gut barrier integrity and inflammatory response of broilers raised in a stressful tropical environment by Sunisa Khongthong, Pipat Piewngam, Natthrit Roekngam, Prapot Maliwan, Sonsawan Kongpuckdee, Juthatip Jeenkeawpleam, Prawit Rodjan

“…Our findings provide new insights and evidence supporting the application of B. subtilis 14823 for enhancing growth performance, gut barrier integrity, and modulating inflammatory cytokines in broilers.…”
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