Food insecurity and ultra-processed food consumption in the Health and Retirement Study: Cross-sectional analysis by Abeer A. Aljahdali

“…Food insecurity was evaluated in the 2013 HRS Health Care and Nutrition Study using the six-item Short Form Food Security Survey Module. Dietary intake was assessed using a food frequency questionnaire, and UPFs, quantified using the NOVA food classification system, were expressed as a percentage of total energy intake. …”
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Shattering the Amyloid Illusion: The Microbial Enigma of Alzheimer’s Disease Pathogenesis—From Gut Microbiota and Viruses to Brain Biofilms by Anna Onisiforou, Eleftheria G. Charalambous, Panos Zanos

“…Viral infections like Herpes Simplex Virus Type 1 (HSV-1) and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) may lead to AD by modulating host processes like the immune system. Aβ peptide’s antimicrobial function as a response to microbial infection might inadvertently promote AD. …”
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Exploring Clec9a in dendritic cell-based tumor immunotherapy for molecular insights and therapeutic potentials by Zubair Hussain, Yueteng Zhang, Lu Qiu, Shanshan Gou, Kangdong Liu

“…Abstract The pivotal role of type 1 conventional dendritic cells (cDC1s) in the field of dendritic cell (DC)-based tumor immunotherapies has been gaining increasing recognition due to their superior antigen cross-presentation abilities and essential role in modulating immune responses. This review specifically highlights the C-type lectin receptor family 9 member A (Clec9a or DNGR-1), which is exclusively expressed on cDC1s and plays a pivotal role in augmenting antigen cross-presentation and cytotoxic T lymphocyte (CTL) responses while simultaneously mitigating off-target effects. …”
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Lipid-Derived Mediators in Endogenous Anti-Inflammation and Resolution: Lipoxins and Aspirin-Triggered 15-epi-Lipoxins by Charles N. Serhan, Nan Chiang

“…LXA4 and 15-epi-LXA4 (a member of the ATL series) display leukocyte-selective actions that enable them to serve as endogenous “stop signals” in multicellular events in that they modulate adherence, transmigration, and chemotaxis. …”
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Utilizing Low-cost Mobile Monitoring to Estimate the PM2.5 Inhaled Dose in Urban Environment by Muhammad Miftahul Munir, Martin Adrian, Casmika Saputra, Puji Lestari

“…The MM device consists of a low-cost PM2.5 sensor, temperature and humidity sensor, Wi-Fi module, and microcontroller unit. The MM system (carried on vehicle) has been used to measure PM2.5 concentration, geolocation, and meteorological factors during rush hour. …”
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Tampered text detection via RGB and frequency relationship modeling by Yuxin WANG, Boqiang ZHANG, Hongtao XIE, Yongdong ZHANG

“…In recent years, the widespread dissemination of tampered text images on the Internet constitutes an important threat to the security of text images.However, the corresponding tampered text detection (TTD) methods have not been sufficiently explored.The TTD task aims to locate all text regions in an image while judging whether the text regions have been tampered with according to the authenticity of the texture.Thus, different from the general text detection task, TTD task further needs to perceive the fine-grained information for real-world and tampered text classification.TTD task has two main challenges.One the one hand, due to the high similarity in texture between real-world texts and tampered texts, TTD methods that only learn from RGB domain features have limited capability to distinguish these two-category texts well.On the other hand, as the different detecting difficulty exists in real-world texts and tampered texts, the network cannot well balance the learning process of the two-category texts, resulting in the imbalance detection performance between real-world and tampered texts.Compared with RGB domain features, the discontinuity of text texture in frequency domain can help the network to identify the authenticity of text instances.Accordingly, a new TTD method based on RGB and frequency information relationship modeling was proposed.The features in the RGB and frequency domains were extracted by independent feature extractors respectively.Thus, the identification ability of tampered texture can be enhanced by introducing frequency information during the texture perception.Then, a global RGB-frequency relationship module (GRM) was introduced to model the texture authenticity relationship between different text instances.GRM referred to the RGB-frequency features of other text instances in the same image to assist in judging the authenticity of the current text instance, which solved the problem of imbalanced detection performance.Furthermore, a new TTD dataset (Tampered-SROIE) was proposed to evaluate the effectiveness of proposed method, which contains 986 images (626 training images and 360 test images).By evaluating on the Tampered-SROIE, the proposed method obtains 95.97% and 96.80% in F-measure for real-world and tampered texts respectively and reduces the imbalanced detection accuracy by 1.13%.The proposed method will give new insights to the TTD community from the perspective of network structure and detection strategy.Tampered-SROIE also provides an evaluation benchmark for future TTD methods.…”
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Association of the Genetic Polymorphisms in Transcription Factor 7-Like 2 and Peroxisome Proliferator-Activated Receptors-γ2 with Type 2 Diabetes Mellitus and Its Interaction with... by Habiba Al-Safar, Ahmed Hassoun, Shaikha Almazrouei, Wala Kamal, Bachar Afandi, Naushad Rais

“…Our case-control study is the first of its kind in Emiratis which establishes TCF7L2 rs10885409 C allele as a T2DM risk factor in Emiratis and this association is modulated by obesity status. We also confirmed that Pro12Ala mutation in PPAR-γ2 is not associated with T2DM risk in this population.…”
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Bio-Optical Response of Phytoplankton and Coloured Detrital Matter (CDM) to Coastal Upwelling in the Northwest South China Sea by Guifen Wang, Wenlong Xu, Shubha Sathyendranath, Wen Zhou, Wenxi Cao

“…The relationship between the absorption coefficient of CDM at 443 nm, <i>a</i>_CDM(443), and Chl-a exhibited distinct differences between waters in upper ocean and in bottom layers, with the threshold depth being modulated by shelf topography. Our results highlight the utility of bio-optical observations with high resolution for better understanding the coupling between physical forcing and biogeochemical variability.…”
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Association of food security with cardiometabolic health during young adulthood: cross-sectional comparison of American Indian adults with other racial/ethnic groups by Cassandra J Nikolaus, Anna Zamora-Kapoor, Luciana E Hebert, Ka'imi Sinclair

“…Future work should capitalise on longitudinal data and the US Department of Agriculture’s Food Security Survey Modules.…”
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miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding by Juan Wen, Baiyi Tang, Lan Guo, Wei Chen, Xiaohong Tang

“…The present study was to examine whether miR-145 modulates phenotypic transformation of VSMCs under normal state and synthetic state and to explore the possible role of ADAM17-mediated ACE2 shedding and ACE2-Ang-(1–7)-Mas receptor axis. …”
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Oral Cancer Stem Cell-Derived Small Extracellular Vesicles Promote M2 Macrophage Polarization and Suppress CD4+ T-Cell Activity by Transferring UCA1 and Targeting LAMC2 by Lan Wu, Sai Ye, Yilin Yao, Chenping Zhang, Wei Liu

“…Mechanistically, we revealed that the lncRNA UCA1, by binding to miR-134, modulated the PI3K/AKT pathway in macrophages via targeting LAMC2. …”
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Automatic image generation and stage prediction of breast cancer immunobiological through a proposed IHC-GAN model by Afaf Saad, Noha Ghatwary, Safa M. Gasser, Mohamed S. ElMahallawy

“…We propose a new IHC-GAN that enhances the Pix2PixHD model into a dual generator module, improving its performance and simplifying its structure. …”
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Curative Effect of AD-MSCs against Cisplatin-Induced Hepatotoxicity in Rats is Potentiated by Azilsartan: Targeting Oxidative Stress, MAPK, and Apoptosis Signaling Pathways by Amany Abdlrehim Bekhit, Olivia N. Beshay, Michael A. Fawzy, Sara Mohamed Naguib Abdel-Hafez, Gaber El-Saber Batiha, Farid S. Ataya, Moustafa Fathy

“…In conclusion, the present findings demonstrated that AZIL improves the hepatoprotective potential of AD-MSCs against CISP-induced hepatotoxicity by modulating oxidative stress, mitogen-activated protein kinase, and apoptotic pathways.…”
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Subminute thermal damage to cell types present in the skin by Meagan Doppegieter, Ton G. van Leeuwen, Angela van Weert, Maurice C.G. Aalders, Erik N.T.P. Bakker

“…Damage to these cells may aid in modulating the neuro-inflammatory pathways in psoriasis. …”
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Pathological manifestations in lymphatic filariasis correlate with lack of inhibitory properties of IgG4 antibodies on IgE-activated granulocytes. by Ulrich F Prodjinotho, Charlotte von Horn, Alex Y Debrah, Linda Batsa Debrah, Anna Albers, Laura E Layland, Achim Hoerauf, Tomabu Adjobimey

“…Helminth parasites are known to be efficient modulators of their host's immune system. To guarantee their own survival, they induce alongside the classical Th2 a strong regulatory response with high levels of anti-inflammatory cytokines and elevated plasma levels of IgG4. …”
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Urban versus rural older adults: occupational balance and quality of life comparison by Emel Pekçetin, Serkan Pekçetin, Emine Sağlamoğlu, Gamze Ekici

“…OB of the participants was evaluated with the Occupational Balance Questionnaire 11-T (OBQ 11-T) The QoL of older adults assessed by the World Health Organization Quality of Life – OLD module (WHOQOL-OLD). Results The median OBQ11-T total score was 21.00 (7.00) in the urban area group and 20.00 (5.00) in the rural area group. …”
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Expression divergence of BAG gene family in maize under heat stress by Babar Farid, Muhammad Abu Bakar Saddique, Muhammad Hammad Nadeem Tahir, Rao Muhammad Ikram, Zulfiqar Ali, Waseem Akbar

“…Once the plant is under heat stress, the BAG genes act as co-chaperones and modulate the molecular functions of HSP70/HSC70 saving the plant from the damage of high temperature stress. …”
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The Mechanism of Acupuncture Therapy for Migraine: A Systematic Review of Animal Studies on Rats by An Y, Zhang J, Ren Q, Liu J, Liu Z, Cao K

“…It also reduces the levels of inflammatory cytokines, thereby mitigating neurogenic inflammation and improving central sensitization.Conclusion: Acupuncture exerts its therapeutic effect on migraine by regulating neurotransmitter release, inhibiting inflammatory responses, modulating central analgesic mechanisms, and suppressing glial cell activation. …”
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Application of Multi Objective land Allocation technique for land use Planning Approach Case study: Hamadan County by hassan mahmodzadeh, sodabeh panahi, mahdi herischian

“…Monitoring lands means contribution of an optimized space for land utilization with realization of common upcoming and related to each other in the past, now and in the future.Therefore, the objective  of  this research is to select the suitable lands  with monitoring lands of view in the city of Hamedan using a Multi-Objective Land Allocation method.The aim of Multi-Objective Land Allocation  method use is to contribute  selection of proper lands with monitoring approach based on ideal levels concept which have been executed by 3 different ecologic, socio-economic and strategic aspects existing in the territory.The examined use include agricultural use (water system or dry farming), pasturing use and urban use which based on the highest weight of independent variables, the area has been allocated to mentioned use with land monitoring approach.In what follows, the land suitability map is obtained through MCE operation for each type of land use and the obtained land suitability areas were calculated using these maps for which the results are as follows: irrigated agriculture with 601.176 hectares, dryland farming with 961.193 hectares, urban suitability with 762.984, and rangeland management suitability with 960.552 hectares which is an important criterion for determining the area for implementing MOLA.In the next step, it was time for implementing MOLA module for resolving the contradictions among the  uses.The results of MOLA showed that in average for the three studied aspects, the maximum area was associated with dryland farming with 364.4 hectares which is equivalent to 32% of the studied uses and the maximum weight of 0.4 was associated with irrigated agriculture.These resulted were obtained based on five factors (i.e. the current area of each land use, the favorable area for each land use based on MCE method, the occupational dependencies of different individuals to each land uses, prioritizing the ecological, economic, and social aspects of each land use).Finally, the results showed that selecting the suitable lands with spatial planning point of view using a Multi-Objective Land Allocation method is carried out properly through economic, social, and ecological aspects.…”
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The Use of Trichostatin A during Pluripotent Stem Cell Generation Does Not Affect MHC Expression Level by Sara Farahi, Sara Hosseini, Hossein Ghanbarian, Seyed Mahmoud Hashemi, Mohammad Salehi, Samaneh Hosseini

“…Highly efficient generation of PSCs through chromatin modulators such as trichostatin A (TSA) might change their MHC molecule expression profile. …”
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