Traffic-related-air-pollutant PM2.5 Caused Toxicity on Caenorhabditis elegans with Cotreatment of High-dose Glucose and Tempeh by Jian-He Lu, Ming-Hsien Tsai, Sen-Ting Huang, Jia-De Lee, Ta-Chih Hsiao, Wan Nurdiyana Wan Mansor, How-Ran Chao

“…These findings reveal that co-exposure to TRAP PM2.5 and high-dose glucose causes more serious health effects, while tempeh could modulate oxidative stress which ameliorated TRAP PM2.5-induced and hyperglycemia-induced toxicological effects.…”
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Multiscale Attention Feature Fusion Based on Improved Transformer for Hyperspectral Image and LiDAR Data Classification by Aili Wang, Guilong Lei, Shiyu Dai, Haibin Wu, Yuji Iwahori

“…First, a multiscale fusion Swin transformer module is employed to eliminate information loss in feature propagation, which explores deep spatial–spectral features of HSI while extracting height information from LiDAR data. …”
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Restriction of mitochondrial oxidation of glutamine or fatty acids enhances intracellular growth of Mycobacterium abscessus in macrophages by Ho Won Kim, Ji Won Lee, Hoe Sun Yoon, Hwan-Woo Park, Young Ik Lee, Sung Ki Lee, Jake Whang, Jong-Seok Kim

“…Notably, Mab infection also modulated mitochondrial substrate preferences, increasing fatty acid oxidation capabilities while revealing significant changes in glutamine dependency and flexibility. …”
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Thermocapillary convection in superimposed fluids confined within superhydrophobic surfaces of a microchannel by Radi A. Alsulami, Kanchathan Wasuwatthanakul, Kannan Premnath, Mutabe Aljaghtham, Saad Adam

“…These results elucidate the role of the competing effects of the wall shear variations due to slip and the thermocapillary motions in the bulk regions facilitated by the viscous forces, which can be exploited in modulating mixing and transport in microchannels.…”
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Proximity‐dependent biotinylation reveals an interaction between ubiquitin‐specific peptidase 46 and centrosome‐related proteins by Kazuma Yoshioka, Reiko Nakagawa, Chi Lieu Kim Nguyen, Hayate Suzuki, Kiyohiro Ishigaki, Seiya Mizuno, Tsukasa Okiyoneda, Shizufumi Ebihara, Kazuya Murata

“…Protein ubiquitination extensively modulates protein functions and controls various biological processes, such as protein degradation, signal transduction, transcription, and DNA repair. …”
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Acute effect of a Mediterranean-style dietary pattern (MDP) on mood, anxiety and cognition in UK adults with mild to moderate anxiety and depression: the MediMood randomised contro... by Emma Stevenson, Amy Jennings, Anne Marie Minihane, Rachel Gillings, Alpar Lazar, M Hornberger, Saber Sami, Latife Esgunoglu, Marrium Liaquat, Adrian Leddy, Jon Brooks, William Penny

“…Evidence of the acute (defined as postprandial to 1 week) effects of an MDP on brain function, mood, cognition and important modulators, including sleep and the gut microbiota is limited. …”
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Inducing aggresome and stable tau aggregation in Neuro2a cells with an optogenetic tool by Shigeo Sakuragi, Tomoya Uchida, Naoki Kato, Boxiao Zhao, Toshiki Takahashi, Akito Hattori, Yoshihiro Sakata, Yoshiyuki Soeda, Akihiko Takashima, Hideaki Yoshimura, Gen Matsumoto, Hiroko Bannai

“…This study describes a novel optogenetic module, OptoTau, which is a human tau with the P301L mutation fused with a photosensitive protein CRY2olig, inducing various forms of tau according to the temporal pattern of blue light illumination pattern. …”
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Altered cytoskeleton dynamics in patient-derived iPSC-based model of PCDH19 clustering epilepsy by Rossella Borghi, Stefania Petrini, Valentina Apollonio, Marina Trivisano, Nicola Specchio, Sandra Moreno, Enrico Bertini, Marco Tartaglia, Claudia Compagnucci

“…We show that iPSC-derived cortical neurons are characterized by altered cytoskeletal dynamics, suggesting that this protocadherin has a role in modulating stability of MFs and MTs. Consistently, the levels of acetylated-tubulin, which is related with stable MTs, are significantly increased in cortical neurons derived from the patient’s iPSCs compared to control cells, supporting the idea that the altered dynamics of the MTs depends on their increased stability. …”
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Lipids in parenteral nutrition – expert consensus statements: Translating guidelines into clinical practice by Robert G. Martindale, Philip C. Calder, Sarah V. Cogle, David C. Evans, Leah Gramlich, Stephen A. McClave, Manpreet S. Mundi, Maurizio Muscaritoli, Reid Nishikawa, Jayshil Patel, Lorenzo Pradelli, Martin Rosenthal, Christian Stoppe, Kelly A. Tappenden, Malissa Warren, Dan Waitzberg, Paul E. Wischmeyer, Stanislaw Klek

“…In addition, lipids modulate a variety of biological functions, including inflammatory and immune responses. …”
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Placenta-derived mesenchymal stem cells protect against diabetic kidney disease by upregulating autophagy-mediated SIRT1/FOXO1 pathway by Honghong Liu, Jiao Wang, Guanru Yue, Jixiong Xu

“…Thus, P-MSCs can significantly improve renal damage and reduce podocyte injury in DKD rats by modulating the SIRT1/FOXO1 pathway and enhancing podocyte autophagy.…”
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Si-Wu-Tang improves liver fibrosis by restoring liver sinusoidal endothelial cell functionality and reducing communication with hepatic stellate cells by Le Wang, Jiaorong Qu, Jianan Li, Xiaoyong Xue, Lingling Qin, Yufei Li, Yuanfeng Dou, Xiaohong Mu, Xiaojiaoyang Li

“…During liver fibrosis, liver sinusoidal endothelial cells (LSECs) undergo phenotypic changes and also play a role in modulating cellular communications. Si-Wu-Tang (SWT), a traditional Chinese herbal remedy, has been extensively studied for its effectiveness in treating hematological, gynecological and hepatic diseases. …”
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GTPase GPN3 facilitates cell proliferation and migration in non-small cell lung cancer by impeding clathrin-mediated endocytosis of EGFR by Linlin Xu, Jiankun Guo, Xinsheng Xie, Hailong Wang, Alan Jiang, Changhua Huang, Hua Yang, Shiwen Luo, Limin Chen

“…In this study, we demonstrate that GPN3 interacts with clathrin light chain A (CLTA), a vesicle coat protein, as well as clathrin-mediated endocytosis associated modulators AP2B1 and AP2S1. Upregulation of GPN3 leads to the inhibition of clathrin-coated pit invagination. …”
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Detection and interpretation of the time-varying seasonal signals in China with multi-geodetic measurements by Liansheng Deng, Yugang Xiao, Qusen Chen, Wei Peng, Zhao Li, Hua Chen, Zhiwen Wu

“…The results reveal that all CMONOC time series exhibit seasonal signals characterized by amplitude and phase modulations, and the SSA method outperforms the traditional least squares fitting (LSF) method in extracting and interpreting the time-varying seasonal signals from the original time series. …”
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Deep Joint Demosaicking and Super-Resolution for Spectral Filter Array Images by Abdelhamid N. Fsian, Jean-Baptiste Thomas, Jon Y. Hardeberg, Pierre Gouton

“…To this end, we use a two-branch framework, namely a pseudo-panchromatic image network and a pre-demosaicking sub-branch coupled with a novel deep residual demosaicking and super resolution module. This holistic approach ensures a more coherent and optimized restoration process, mitigating the risk of error accumulation and preserving image quality throughout the reconstruction pipeline. …”
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Exploring the Therapeutic Potential of Cannabidiol in U87MG Cells: Effects on Autophagy and NRF2 Pathway by Laura Giannotti, Benedetta Di Chiara Stanca, Francesco Spedicato, Daniele Vergara, Eleonora Stanca, Fabrizio Damiano, Luisa Siculella

“…These findings highlight the therapeutic potential of CBD, suggesting that modulating NRF2 and autophagy pathways could represent a promising strategy for glioblastoma treatment.…”
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IMPLEMENTATION OF MICROLEARNING TECHNOLOGY FOR ECONOMICS STUDENTS THROUGH ONLINE COURSES by Olena Hlazunova, Ralf Schlauderer, Valentyna Korolchuk, Tetiana Voloshyna, Taisia Sayapina, Inna Kostenko, Roman Zolotukha

“…Microlearning is a modern learning technology that involves short, intensive training modules focused on the development of specific theoretical knowledge and practical skills. …”
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Regulation of IL-33 by Oncostatin M in Mouse Lung Epithelial Cells by Carl D. Richards, Laura Izakelian, Anisha Dubey, Grace Zhang, Steven Wong, Karen Kwofie, Aatif Qureshi, Fernando Botelho

“…IL-33 modulates both innate and adaptive immune responses at tissue sites including lung and may play critical roles in inflammatory lung disease. …”
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Phytoreduced gold nanoparticles from vitalmelon promote white adipocyte browning in murine cells by targeting phospholipase D2 by Sun Young Park, He mi Kang, Kangmin Park, Lu Guo, Jin-Woo Oh, Geuntae Park, Nam Jun Kang, Young-Whan Choi

“…These findings suggest that VW-GNPs represent a promising novel therapeutic strategy to combat obesity by modulating adipocyte metabolism and increasing energy expenditure via adipocyte browning.…”
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Exposure to PM2.5 and its components leads to obesity: role of socioeconomic status by Yindi Peng, Yamin Zhao, Minzhen Wang, Yingqian He, Lulu Zhang, Yanan Zhao, Jing Liu, Shan Zheng

“…Abstract Exposure to air pollutants is linked to an increased risk of obesity, and socioeconomic status (SES) could modulate this risk. We employed the “Jinchang Cohort” as a platform to investigate the influence of SES (education level, monthly income per household, and marital status) on the obesity risk associated with PM2.5 and its constituents. …”
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Cigarette and e-cigarette reversely regulated autophagy via distinct level of ROS in vitro by Yao Wang, Jialing Zhong, Zuyi Jin, An Luo, Zehong Wu, Xingtao Jiang, Jianwen Chen, Peiqing Liu, Min Li

“…Scavenge of ROS clearly eliminates the autophagy modulated by both CSC and EAC. These findings contribute to a comprehensive understanding of the cytotoxicity of e-cigarettes and conventional cigarettes, providing a scientific basis for health risk assessment and regulatory mechanisms.…”
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