Drug Target Investigation of <i>N</i>-<i>p</i>-Coumaroyl-<i>N</i>’-Caffeoylputrescine, a Naturally-Occurring Alkaloid Derived from <i>Saxifraga tangutica</i> by Chuang Liu, Jun Dang, Minchen Wu

“…An in vitro study on liver (HepG2) cells and breast (MCF-7) cancer cells revealed that PCC modulates HSP90AA1, subsequently affecting Mut-p53 expression, triggering a cascade effect that reduced adriamycin-induced drug resistance in cells. …”
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Utilization of a Lightweight 3D U-Net Model for Reducing Execution Time of Numerical Weather Prediction Models by Hyesung Park, Sungwook Chung

“…We also propose a convolutional block attention module-based Half-UNet (CH-UNet), a lightweight 3D-based U-Net architecture, for faster deep-learning computations. …”
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Temporal–Spatial Acupuncture Effects on Poststroke Sensorimotor Cortex via Yanglingquan (GB34) by Ruoyi Liu, Yue Wang, Myadagbadam Boldbayar, Yuanyuan Li, Chen Chen, Xin Yu, Tianjiao Xu, Muzhao Zhang, Yihuai Zou, Hua Zhang

“…During finger movement, signal patterns matched the task module (movement–rest–movement–rest). In acupuncture, response patterns showed a high–low–high–low fluctuation trend across time segments. …”
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Diversity in Notch ligand-receptor signaling interactions by Rachael Kuintzle, Leah A Santat, Michael B Elowitz

“…These components are expressed in diverse combinations in different cell types, interact in a many-to-many fashion, both within the same cell (in cis) and between cells (in trans), and their interactions are modulated by Fringe glycosyltransferases. A fundamental question is how the strength of Notch signaling depends on which pathway components are expressed, at what levels, and in which cells. …”
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SLFCNet: an ultra-lightweight and efficient strawberry feature classification network by Wenchao Xu, Yangxu Wang, Jiahao Yang

“…This innovative system incorporates a lightweight encoder and a self-designed feature extraction module called the Combined Convolutional Concatenation and Sequential Convolutional (C3SC). …”
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Expression and Secretion of CXCL-8 and CXCL-10 From Mycobacterium Bovis BCG-Infected Human Epithelial Cells: Role of IL-4 by Patricia Méndez-Samperio, Elena Miranda, Abraham Vázquez

“…CXC chemokine release can be modulated by Th2-derived cytokines. Interleukin(IL)-4 is one of the cytokines that are the hallmark of the Th-2 response, and plays an important role in human tuberculosis. …”
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Molecular monitoring of short- and long-term transcriptional effects of hair growth stimulating agents. by Sabrina K Henne, Lara M Hochfeld, Werner Bartmann, Thomas Welss, Markus M Nöthen, Stefanie Heilmann-Heimbach

“…Differential expression analyses identified 52 differentially expressed genes and 17 modulated pathways following treatment with the three hair growth stimulating agents. …”
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Stress contingent changes in Hog1 pathway architecture and regulation in Candida albicans. by Alison M Day, Min Cao, Alessandra da Silva Dantas, Olga Ianieva, Carmen Herrero-de-Dios, Alistair J P Brown, Janet Quinn

“…Although this three-tiered SAPK signalling module is well characterised, it is unclear how Hog1 activation is regulated in response to different stresses. …”
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Embedding Trust in the Media Access Control Protocol for Wireless Networks by Chaminda Alocious, Hannan Xiao, Bruce Christianson, Joseph Spring

“…This issue is further compounded when receivers such as Wi-Fi hotspots, normally trusted by other module nodes, also misbehave. Such issues, their detection, and mitigation have, we believe, not been sufficiently addressed in the literature. …”
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Exosomes and microRNAs as mediators of the exercise by Haoyuan Li, Guifang Liu, Bing Wang, Mohammad Reza Momeni

“…Environmental factors, such as physical exercise, can modulate miRNA expression and induce targeted changes in gene transcription. …”
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Molecular Modeling Studies of Substituted 2,4,5-Trisubstituted Triazolinones Aryl and Nonaryl Derivatives as Angiotensin II AT1 Receptor Antagonists by Mukesh C. Sharma, D. V. Kohli, Smita Sharma

“…Pharmacophore hypotheses were generated by the mol sign module and found to contain common features like hydrogen bond donor acceptor, donor, positive, negative ionizable, and hydrophobic features. …”
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Effect of Future Climate Change on Stratosphere-to-Troposphere-Exchange Driven Ozone in the Northern Hemisphere by Shovan Kumar Sahu, Lei Chen, Song Liu, Jia Xing, Rohit Mathur

“…Tropospheric burden of O3 is modulated not only by anthropogenic and natural precursor emissions, but also by the downward transport of O3 associated with stratosphere to troposphere exchange (STE). …”
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SC-ResNeXt: A Regression Prediction Model for Nitrogen Content in Sugarcane Leaves by Zihao Lu, Cuimin Sun, Junyang Dou, Biao He, Muchen Zhou, Hui You

“…The Self-Attention (SA) mechanism and Convolutional Block Attention Module (CBAM) have been incorporated into the ResNeXt101 model to enhance the model’s focus on key image features and its information extraction capability. …”
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Environmental-oriented development of enterprises of agricultural industry and advanced training of personnel in agricultural environmental management by Yu. D. Vishnyakov, S. P. Kiseleva, L. V. Makolova, V. V. Pham, T. T. Vu Huong

“…The structure of the proposed educational program “Agroecological Management” contains disciplines (modules) of a theoretical and applied nature, that are relevant for the study by specialists of the agro-industrial complex in accordance with the need to solve modern environmental problems.…”
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ESD-YOLOv8: An Efficient Solar Cell Fault Detection Model Based on YOLOv8 by Lingyun Zhang, Xu Wu, Zihan Liu, Panlin Yu, Mingfen Yang

“…The detection of small defects is enhanced by optimising the YOLOv8 architecture, removing the P5 layer, introducing the small target sensitive P2 layer, and integrating the EMA attention mechanism and the C2f_EMA module. Meanwhile, guided by the CloAttention mechanism, a feature fusion layer has been designed to focus the model&#x2019;s attention on small target defect features in the P2 layer, thereby improving the accuracy of defect location. …”
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Impact of Tibetan plateau warming amplification on the interannual variations in East Asia Summer precipitation by XiaoJing Jia, XinHai Chen, Wei Dong, Hao Ma, JingWen Ge, QiFeng Qian

“…Our analysis reveals that TA enhances the tripole Pre_EA pattern by modulating moisture transport and vertical motion in the East Asia-North Pacific regions. …”
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Leukemia Stem Cell-Released Microvesicles Promote the Survival and Migration of Myeloid Leukemia Cells and These Effects Can Be Inhibited by MicroRNA34a Overexpression by Yue Wang, Qian Cheng, Jing Liu, Min Dong

“…In summary, LMVs support AML cell malignance and modulating miR34a could offer a new approach for the management of AML.…”
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Enhancing Intelligent Road Target Monitoring: A Novel BGS-YOLO Approach Based on the YOLOv8 Algorithm by Xingyu Liu, Yuanfeng Chu, Yiheng Hu, Nan Zhao

“…Following this, this paper introduces the Global Attention Module (GAM), which markedly improves the efficiency and accuracy of extracting key target information in complex data environments. …”
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Impact of OER-assisted Problem-based Learning on Creative Thinking and Self-Efficacy in Physics Education by Agung Sedayu, Herpratiwi Herpratiwi, Dwi Yulianti, I Wayan Distrik

“…Consequently, educational practitioners in the field of physics education, such as lecturer and teacher can implement PBL assisted by OER, such as e-book, e-module, web-based environment, etc., to optimize students’ creative thinking abilities or skills in which they can enhance their creative thinking, so getting the high achievement in physics subject. …”
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Correlation between uterine microbiota and pregnancy outcomes of embryo transfer in overweight and obese women by Ying Yan, Ying Li, Lingling Wu, Yuxuan Zhang, Hong Guo, Yazhong Ji

“…In individuals with higher BMI, pathogenic bacteria are more likely to impair endometrial receptivity, ultimately leading to adverse pregnancy outcomes. Therefore, modulating the uterine microbiota in overweight/obese women may improve assisted reproductive technology success rates.…”
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