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8481
DualCFGL: dual-channel fusion global and local features for sequential recommendation
Published 2024-12-01“…To enable the model to consider both the global and local preferences of users, we design an adaptive orthogonal fusion module, which effectively fuses the two preferences and enables the two feature types to complement and enhance each other. …”
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8482
Rap1 Guanosine Triphosphate Hydrolase (GTPase) Regulates Shear Stress-Mediated Adhesion of Mesenchymal Stromal Cells
Published 2025-01-01“…In a competitive murine short-term homing model with i.v. co-injection of Rap1A+B siRNA-treated and control MSCs that were labeled with PKH 26 and PKH 67 fluorescent dyes, the Rap1A+B siRNA-treated MSCs were detected at increased frequencies in blood, liver, and spleen compared to control MSCs. Thus, Rap1 GTPase modulates the adhesion and migration of MSCs in vitro and may increase the bio-availability of i.v.…”
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8483
Pre-treatment subjective sleep quality as a predictive biomarker of tDCS effects in preclinical Alzheimer's disease patients: Secondary analysis of a randomised clinical trial.
Published 2025-01-01“…<h4>Background</h4>Despite transcranial direct current stimulation (tDCS) has demonstrated encouraging potential for modulating the circadian rhythm, little is known about how well and sustainably tDCS might improve the subjective sleep quality in older adults. …”
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8484
Assessing brain-muscle networks during motor imagery to detect covert command-following
Published 2025-02-01“…For the 15/38 participants who showed motor imagery, as indexed by common spatial filters and linear discriminant analysis, we contrasted the configuration of the networks during imagined movement and resting state at the group level, and subject-level classifiers were implemented using as features the weights of the NMF together with trial-wise power modulations and heart response to classify resting state from motor imagery. …”
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8485
The preference for surprise in reinforcement learning underlies the differences in developmental changes in risk preference between autistic and neurotypical youth
Published 2025-01-01“…The computational modeling approach with reinforcement learning models revealed that individual preferences for surprise modulated such preferences. Conclusions These findings indicate that for NTP people, adolescence is a developmental period involving risk preference, possibly due to lower surprise aversion. …”
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8486
The Plurality of Goal-setting in Pedagogical Activity: Integration of Mathematics on a Chessboard
Published 2019-04-01“…Therefore, the authors propose to study the features of goal-setting with a plurality of alternatives during the process of training bachelors and masters majoring in pedagogy within the disciplines of the methodical module. The goal of the article is to theoretically substantiate, develop and implement the technology of integrative teaching mathematics on the basis of chess game with the actualization of the phenomenon of a plurality of goal-setting as an effective mechanism of content modernization in training programs of future math teachers. …”
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8487
Impact of plasma discharge pressure on implant surface properties and osteoblast activities in vacuum-assisted plasma treatment
Published 2024-12-01“…Implant materials were treated with plasmas under varying discharge conditions, with pre-pumping times of 10 s and 20 s, thereby modulating the pressure during plasma treatments. Through optical emission spectroscopy, we demonstrated that the 5 Torr operational condition, achieved by 20-s pre-pumping, generated a greater density of excited nitrogen species and provided more stable plasma compared to the 16 Torr condition, achieved by 10-s pre-pumping. …”
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8488
Definition of a Novel Cuproptosis-Relevant lncRNA Signature for Uncovering Distinct Survival, Genomic Alterations, and Treatment Implications in Lung Adenocarcinoma
Published 2022-01-01“…Cuproptosis genes displayed aberrant expression and widespread genomic alterations across LUAD, potentially modulated by m6A/m5C/m1A RNA modification mechanisms. …”
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8489
Effectiveness of menstrual hygiene management training to enhance knowledge, attitude, and practice among adolescents in Sindhupalchowk, Nepal.
Published 2025-01-01“…<h4>Methods</h4>A school-based study was conducted in Indrawati rural municipality of Sindhupalchowk district in Nepal. 427 participants (175 boys and 252 girls), aged 11-13, completed a questionnaire evaluating MH KAP before receiving a structured training module on MH provided by experienced trainers from Putali Nepal using the Menstrupedia tool. …”
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8490
An explainable deep learning model for diabetic foot ulcer classification using swin transformer and efficient multi-scale attention-driven network
Published 2025-02-01“…These blocks dynamically adjust kernel sizes and leverage attention modules, enabling effective feature extraction. To the best of our knowledge, this is the first work reporting the findings of a dual track architecture for DFU classification, leveraging Swin transformer and EMADN networks. …”
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8491
PPIH is a novel diagnostic biomarker associated with immune infiltration in cholangiocarcinoma
Published 2025-02-01“…PPIH may also play a role in modulating the immune microenvironment, contributing to poor prognosis.…”
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8492
3D-AOCL: Analytic online continual learning for imbalanced 3D point cloud classification
Published 2025-01-01“…This approach utilizes Analytic Learning to update parameters and integrates a feature fusion module along with a category balancer to address the above issues. …”
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8493
Performance Comparison of Different Neuroimaging Methods for Predicting Upper Limb Motor Outcomes in Patients after Stroke
Published 2022-01-01“…We used the upper extremity module of the Fugl-Meyer assessment (UE-FM) within 1 month of onset (baseline) and again 3 months poststroke. sMRI (T1- and T2-based) was used to measure CST-weighted lesion load (CST-wLL), and DTI was used to measure the fractional anisotropy asymmetry index (FAAI) and the ratio of fractional anisotropy (rFA). …”
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8494
Specific nature of the integrative (complex) effect of environmental factors on hazelnut cultivars in the Russian humid subtropics
Published 2021-04-01“…Dependencies between yield and weather were well expressed, with module values of 0.86–1.0 (p < 0.05). The effect size of limiting factors is better measured with the coefficient of determination (%), a direct indicator of the correlations between harvest and weather factors. …”
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8495
Research on Mine-Personnel Helmet Detection Based on Multi-Strategy-Improved YOLOv11
Published 2024-12-01“…Secondly, a novel C3K2_FE module was designed that integrates Faster_block and ECA attention mechanisms. …”
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8496
Involvement of Neuropeptide Y within Paraventricular Nucleus in Electroacupuncture Inhibiting Sympathetic Activities in Hypertensive Rats
Published 2022-01-01“…This study aimed to assess the hypothesis that EA treatment exerts a hypotensive action via suppressing sympathetic activities and modulating neuropeptide Y (NPY) function within the paraventricular nucleus (PVN) of hypertensive rats. …”
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8497
Protease-activated receptor 1 in the pathogenesis of cystic fibrosis
Published 2025-01-01“…Protease-activated receptor 1 (PAR1) is a cell surface receptor activated by serine proteases including neutrophil elastase, which is recognised as a potent modulator of inflammation. While PAR1 is known to play an important role in regulating inflammation, nothing is known about any potential role of this receptor in CF pathogenesis.Methods PAR1 (PAR1-/-) and intestinal-corrected CFTR (Cftr-/-) deficient mice were crossed to generate double knock-out (DKO) mutants lacking both PAR1 and CFTR, as well as matching sibling single mutant and wildtype (WT) littermate controls. …”
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8498
The Regulation Effect of α7nAChRs and M1AChRs on Inflammation and Immunity in Sepsis
Published 2021-01-01“…Firstly, the vagus nerve senses and regulates local or systemic inflammation by means of the Cholinergic Anti-inflammatory Pathway (CAP) and activation of α7-nicotinic acetylcholine receptors (α7nAChRs); thus, α7nAChRs play important roles for the central nervous system (CNS) to modulate peripheral inflammation; secondly, the activation of muscarinic acetylcholine receptors 1 (M1AChRs) in the forebrain can affect the neurons of the Medullary Visceral Zone (MVZ), the core of CAP, to regulate systemic inflammation and immunity. …”
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8499
An Active-Learning Framework for Educating Medical Students on SARS-CoV-2 Variants and COVID-19 Epidemiology [version 1; peer review: 2 approved]
Published 2024-11-01“…Students enrolled in professional healthcare programs benefit from being adept with the evolution and spread of SARS-CoV-2 variants, and a team-based learning module can be helpful for applying foundational concepts to clinical problems. …”
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8500
Pan-Cancer Analysis of the Prognostic and Immunotherapeutic Value of PDGFB
Published 2025-01-01“…Notably, PDGFB was found to be associated with immune modulators. PDGFB, which is involved in various immune responses, influences the malignant characteristics of various cancer types and controls immune cell infiltration. …”
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