LOX-induced tubulointerstitial fibrosis via the TGF-β/LOX/Snail axis in diabetic mice by Yicheng Lu, Heyangzi Li, Mohan Chen, Yicheng Lin, Xiaoming Zhang

“…Moreover, we found that increased LOX prompted partial EMT of renal tubular epithelial cells (RTECs) by modulating the transcription factor Snail both in vivo and in vitro. …”
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Online resources on gene networks containing human and animal data by E. V. Ignatieva, D. A. Afonnikov, N. A.  Kolchanov

“…This review characterizes a number of Internetaccessible information resources oriented to humans and animals and containing data on gene networks and their functional modules. Without pretending to fully cover all information resources containing data related to humans and animals on the subject, the current review was created to report the current status of the problem and to present the criteria according to which we propose to evaluate the utility of webresources for specific research tasks. …”
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Glycosylation of ceramide synthase 6 is required for its activity by Alexandra J. Straus, Grace Mavodza, Can E. Senkal

“…However, the mechanisms by which ceramide modulates ER stress signaling are not well understood. …”
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Integrated analysis of cellulose structure and properties using solid-state low-field H-NMR and photoacoustic spectroscopy by Levente Csóka, Worakan Csoka, Ella Tirronen, Ekaterina Nikolskaya, Yrjö Hiltunen, Bunsho Ohtani

“…Complementing this, we investigate the photo-absorption properties of cellulose fibers under both continuous and modulated irradiation using reversed double-beam photoacoustic spectroscopy (RDB-PAS). …”
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Effect of the overhead height and tilt angle on comprehensive performance of photovoltaic roof based on simulation and experimental methods by Wenheng Zheng, Huihui He, Fuyu Qin, Yuncheng Lan, Yingde Yin

“…Therefore, this paper established a simulated model to investigate the impact of various overhead heights and tilt angles of photovoltaic modules on thermal and electrical performance, as well as energy-saving benefits. …”
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Bioelectronic osteosynthesis plate to monitor the fracture bone healing using electric capacitive variations by Diogo G. Pires, Nuno M. Silva, A. Completo, Marco P. Soares dos Santos

“…Our technology includes a network-architectured capacitive interdigitated system, a Bluetooth module, an analog-to-digital converter, a multiplexer, a microcontroller, and a miniaturized battery. …”
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Engineering a tumor-selective prodrug T-cell engager bispecific antibody for safer immunotherapy by Amelia C. McCue, Stephen J. Demarest, Karen J. Froning, Michael J. Hickey, Stephen Antonysamy, Brian Kuhlman

“…This study showcases an approach to developing immune-modulating therapeutics that prioritizes safety and has the potential to advance cancer immunotherapy treatment strategies.…”
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Development and Complex Dynamics at School Environment by Miguel Angel Fuentes, Juan Pablo Cárdenas, Natalia Carro, Mariana Lozada

“…Our findings show that participating in the intervention positively modulated social interactions since we found an increase in the diversity and quality of positive links and a reduction in negative ones; a higher level of integration, indicated by enhanced positive networks where children with many positive connections tended to connect with those with few links; and more positive interactions between genders. …”
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Inhibition of BRD4 attenuated IFNγ-induced apoptosis in colorectal cancer organoids by Akimi Yonezawa, Kana Shimomura, Koji Okamoto, Haruna Takeda

“…Conclusions Our results showed that the inhibition of Brd4 suppressed IFNγ-induced cytotoxicity by modulating the Jak-Stat pathway. These data suggested that the inhibition of Brd4 could increase cell viability in the cancer microenvironment where IFNγ is abundant, revealing a new aspect of the molecular mechanism of CRC development. …”
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Lifelong learning as a major trend in personnel training: theoretical and practical aspects by Olga Yu. Kalmykova, Natalia V. Ryumina, Svetlana N. Parfenova, Natalya V. Sukhankina

“…The paper analyzes the methods and content of the module Conflict and Stress Management in the Educational Process of the retraining program Teacher of Higher Education. …”
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Beyond modular and non-modular states: theoretical considerations, exemplifications, and practical implications by Francesco Benso, Carlo Chiorri, Eleonora Ardu, Paola Venuti, Angela Pasqualotto, Angela Pasqualotto

“…We begin by analyzing the contributions of Sternberg and Fodor, whose foundational work established the concept of specialized, encapsulated modules within cognitive processes, particularly in the domains of perception and language. …”
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Implementing a Responsible Conduct of Research Curriculum for an Undergraduate Summer Clinical Research Program in Quantitative Sciences by Kay See Tan, Mengmeng Du, Jaya Satagopan, Elena Elkin

“…METHODS Topics in this 7-module RCR workshop are relevant to undergraduate trainees in quantitative fields, many of whom are learning about these concepts for the first time. …”
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Multimodal heterogeneous graph fusion for automated obstructive sleep apnea-hypopnea syndrome diagnosis by Haoyu Wang, Xihe Qiu, Bin Li, Xiaoyu Tan, Jingjing Huang

“…Additionally, a multi-head fusion module combines these features into a unified representation for effective classification, enhancing focus on relevant signal characteristics and cross-modal interactions. …”
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IFN Regulatory Factor 1 Mediates Macrophage Pyroptosis Induced by Oxidized Low-Density Lipoprotein in Patients with Acute Coronary Syndrome by Min Guo, Rui Yan, Hongmei Yao, Liqin Duan, Meng Sun, Zheng Xue, Yongping Jia

“…The overexpression or inhibition of IRF-1 effectively modulated caspase-1 activation, as well as macrophage lysis, expression of gasdermin D-N (GSDMD-N), production of IL-1β and IL-18, and activation of NLRP3-ASC inflammasome, which were all inhibited by caspase-1 inhibitor. …”
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Zonisamide Enhances Motor Effects of Levodopa, Not of Apomorphine, in a Rat Model of Parkinson’s Disease by Haruo Nishijima, Yasuo Miki, Shinya Ueno, Masahiko Tomiyama

“…In conclusion, zonisamide appears to generate its antiparkinsonian effects by modulating levodopa-dopamine metabolism in the parkinsonian striatum.…”
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Overview of Solar Photovoltaic MPPT Methods: A State of the Art on Conventional and Artificial Intelligence Control Techniques by Debabrata Mazumdar, Chiranjit Sain, Pabitra Kumar Biswas, P. Sanjeevikumar, Baseem Khan

“…Well-written descriptions of the features of photovoltaic modules are followed by a variety of effective control strategies, including both AI-based and traditional controllers. …”
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New era, new GOALs: cardiovascular screening and lipid management in cystic fibrosis by Katherine A. Despotes, Agathe S. Ceppe, Jennifer L. Goralski, Scott H. Donaldson

“…While cholesterol levels were historically low in pwCF, higher levels after initiating highly effective modulator therapy (HEMT) have been reported. Mechanisms are unclear and there is little guidance on screening. …”
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A Lactobacillus consortium provides insights into the sleep-exercise-microbiome nexus in proof of concept studies of elite athletes and in the general population by Tindaro Bongiovanni, Marina Santiago, Kinga Zielinska, Jonathan Scheiman, Carolina Barsa, Ralf Jäger, Daniela Pinto, Fabio Rinaldi, Giammaria Giuliani, Tullio Senatore, Aleksandar D. Kostic

“…Conclusion This study provides novel insights into how a multi-strain Lactobacillus probiotic modulates sleep quality, exercise recovery, and gut microbiome composition in both the general population and elite athletes, and introduces potential mechanisms through which this probiotic could be influencing overall health. …”
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Nogo Osing Apps: Aplikasi Smart Farming Buah Naga Berbasis IoT by Maulida Dwi Agustiningsih, Putri Catur Ayu Lestari, Ravika Mutiara Savitrah, Arif Fahmi, Hamdan -

“…Kombinasi arduino, microcontroller, sensor flow, soil moisture dan modul relay dapat memonitoring suhu dan kelembaban tanah guna menghasilkan buah naga yang optimal. …”
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The Interannual Relationship between the Diabatic Heating over the South Asia and the Snow Depth over the Southern Tibetan Plateau in Late Spring to Early Summer: Roles of the Air... by Chengyang Zhang, Zhihai Zheng, Yi Ou, Tuantuan Zhang, Zhixiang Xiao, Sheng Lai, Yuexing Cai, Sirong Chen, Weijian Qin, Hui He

“…But we could not prove that these diabatic heating anomalies can affect the SD over the southern TP by modulating local surface air temperature. This may be limited by the quality of the data and the simulation capability of the simple model.…”
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