Ca²⁺/Calmodulin-Dependent Protein Kinase II (CaMKII) Regulates Basal Cardiac Pacemaker Function: Pros and Cons by Tatiana M. Vinogradova, Edward G. Lakatta

“…The interactions within a “coupled-clock” system are modulated by phosphorylation of surface membrane and sarcoplasmic reticulum proteins. …”
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Sequence-variable attention temporal convolutional network for volcanic lithology identification based on well logs by Hanlin Feng, Zitong Zhang, Chunlei Zhang, Chengcheng Zhong, Qiaoyu Ma

“…A novel Sequence-Variable Attention Mechanism module is designed to effectively extract features by adding the bidirectional attention mechanism, which comprises the sequence attention mechanism and the variable attention mechanism. …”
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A Virtual Reality Platform for Safety Training in Coal Mines with AI and Cloud Computing by Mei Li, Zhenming Sun, Zhan Jiang, Zheng Tan, Jinchuan Chen

“…The system, with browser/client architecture, includes eight modules demonstrating the full procedure of an underground coal mine. …”
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Application of probiotics, prebiotics and synbiotics in patients with breast cancer: a systematic review and meta-analysis protocol for randomised controlled trials by Wenjie Liu, Wenyao Cui, Xinrong Chen, Dan Duan, Maojun Chen

“…Microbial agents play an important role in maintaining the balance of gut microbiota and modulating intestinal immunity, anti-inflammatory and antioxidant effects. …”
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Encrypted traffic identification method based on deep residual capsule network with attention mechanism by Guozhen SHI, Kunyang LI, Yao LIU, Yongjian YANG

“…With the improvement of users’ security awareness and the development of encryption technology, encrypted traffic has become an important part of network traffic, and identifying encrypted traffic has become an important part of network traffic supervision.The encrypted traffic identification method based on the traditional deep learning model has problems such as poor effect and long model training time.To address these problems, the encrypted traffic identification method based on a deep residual capsule network (DRCN) was proposed.However, the original capsule network was stacked in the form of full connection, which lead to a small model coupling coefficient and it was impossible to build a deep network model.The DRCN model adopted the dynamic routing algorithm based on the three-dimensional convolutional algorithm (3DCNN) instead of the fully-connected dynamic routing algorithm, to reduce the parameters passed between each capsule layer, decrease the complexity of operations, and then build the deep capsule network to improve the accuracy and efficiency of recognition.The channel attention mechanism was introduced to assign different weights to different features, and then the influence of useless features on the recognition results was reduced.The introduction of the residual network into the capsule network layer and the construction of the residual capsule network module alleviated the gradient disappearance problem of the deep capsule network.In terms of data pre-processing, the first 784byte of the intercepted packets was converted into images as input of the DRCN model, to avoid manual feature extraction and reduce the labor cost of encrypted traffic recognition.The experimental results on the ISCXVPN2016 dataset show that the accuracy of the DRCN model is improved by 5.54% and the training time of the model is reduced by 232s compared with the BLSTM model with the best performance.In addition, the accuracy of the DRCN model reaches 94.3% on the small dataset.The above experimental results prove that the proposed recognition scheme has high recognition rate, good performance and applicability.…”
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GENomE wide analysis of sotalol-induced IKr inhibition during ventricular REPOLarization, "GENEREPOL study": Lack of common variants with large effect sizes. by Joe-Elie Salem, Marine Germain, Jean-Sébastien Hulot, Pascal Voiriot, Bruno Lebourgeois, Jean Waldura, David-Alexandre Tregouet, Beny Charbit, Christian Funck-Brentano

“…A random subsample of 489 individuals were subjected to a genome-wide-association analysis where 8,306,856 imputed single nucleotide polymorphisms (SNPs) were tested for association with QTc, TpTe and TAmp modulations, as well their derived principal-components, to search for common genetic variants associated with sotalol-induced IKr inhibition. …”
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The R&D of HTR-STAC Program Package: Source Term Analysis Codes for Pebble-Bed High-Temperature Gas-Cooled Reactor by Hongyu Chen, Chuan Li, Haoyu Xing, Chao Fang

“…High-Temperature Gas-Cooled Reactor-Pebble-bed Modules (HTR-PM) design by China is a typical Gen-IV and due to different safety concepts and systems, the implements of source term analysis in light water reactors are not entirely applicable to HTR-PM. …”
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Comparison of Heart Rate Variability and Heart Rate Recovery Indices in Healthy Young Adults after Submaximal Exercise with and without Music Intervention by Saravanan T, Prashanth K S

“…The post-exercise reactivation of the parasympathetic nervous system is thought to have a cardioprotective effect. Music is known to modulate emotions and autonomic nervous system activity. …”
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La rhétorique agonistique du discours sportif : une analyse sémantico-pragmatique des métaphores guerrières dans le journalisme footballistique français by Ala Eddine BAKHOUCH

“…La problématique centrale de cette recherche vise à élucider comment la terminologie martiale, omniprésente dans le journalisme footballistique, influence la construction du sens et module l'interprétation des événements sportifs. Nous postulons que ces choix lexicaux ne sont pas anodins mais participent à une rhétorique agonistique (Mouffe, 2016) qui dramatise et polarise le récit sportif. …”
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Pengembangan panduan konseling rational emotive behavioral teknik dispute cognitive untuk meningkatkan konsep diri dan resiliensi terhadap kemandirian pada siswa by I Gst. Agung Diah Rusdayanti, Ni Ketut Suarni, I Ketut Dharsana, Nyoman Dantes, Putu Ari Dharmayanti

“…Guidance and counseling teachers' efforts to help students develop positive self-concept and resilience towards independence still experience obstacles due to limited facilities in the form of guidance modules that can assist in providing services. This research aims to compile and produce a design for a guidebook, determine the validity of the contents of the guidebook, determine the practicality of implementing the guidebook, and determine the effectiveness of implementing the rational emotive behavioral counseling guidebook, cognitive dispute techniques to increase self-concept and resilience towards independence in students. …”
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Conditioned Medium from Human Amnion-Derived Mesenchymal Stem Cells Regulates Activation of Primary Hepatic Stellate Cells by Qingjie Fu, Shunsuke Ohnishi, Naoya Sakamoto

“…These findings demonstrated that hAMSC-CM can modulate HSC function via secretory factors and provide a plausible explanation for the protective role of hAMSCs in liver fibrosis.…”
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Microsporidian Nosema bombycis secretes serine protease inhibitor to suppress host cell apoptosis via Caspase BmICE. by Maoshuang Ran, Jialing Bao, Boning Li, Yulian Shi, Wenxin Yang, Xianzhi Meng, Jie Chen, Junhong Wei, Mengxian Long, Tian Li, Chunfeng Li, Guoqing Pan, Zeyang Zhou

“…Apoptosis is an important defense mechanism by which host cell control intracellular pathogens. Microsporidia modulating host cell apoptosis has been reported previously, however the molecular mechanism is not yet clear. …”
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Dual Control of Host Actin Polymerization by a Legionella Effector Pair by M. Pillon, C. Michard, N. Baïlo, J. Bougnon, K. Picq, O. Dubois, C. Andrea, L. Attaiech, V. Daubin, S. Jarraud, E. Kay, P. Doublet

“…We demonstrated that LegK2 and VipA do not modulate each other’s activity in a “metaeffector” relationship. …”
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Integration of predictive and computational intelligent techniques: A hybrid optimization mechanism for PMSM dynamics reinforcement by Shaswat Chirantan, Bibhuti Bhusan Pati

“…The heart of the work deals with the optimal switching states and subsequent voltage injection to the inverter fed PMSM drive by a predefined minimization principle of a current modulated objective function, where MPC constitutes an integral finite control set (IFCS) mechanism for voltage vector selection and thereby selects the optimized integral gains Kd and Kq for direct and quadrature axes, respectively, with the FCS gain Kfcs obtained from implemented intelligent techniques. …”
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Cultural Aspects of Type-2 Diabetes-related Social Stigma: A Cultural Epidemiological Study among General Community Members in Urban Pune, India by Abhay Machindra Kudale, Mayuri Dnyandeo Ghawat, Akshada Vikram Gopale, Mugdha Sharad Phutane, Saju Joseph

“…A cross-sectional community-based survey using a locally adapted Explanatory Module Interview Catalog was conducted among 100 randomly selected general community members who did not have diabetes from slum pockets of Pune city. …”
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Chelate compounds and their use for correction of trace element deficiencies in livestock (review) by A. G. Koshchaev, N. E. Gorkovenko, A. V. Kosykh, D. V. Antipova

“…Due to the immunostimulatory activity resulting from increase in the content of sialic acids, properdin, ceruloplasmin, gamma globulin protein fraction, the metal chelates (copper, cobalt, iodine) can be used as immune response modulators. Iron chelate compounds are used for therapy and prevention of iron deficiency anemias not only in veterinary, but also in human medicine. …”
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Interpretable DWT-1DCNN-LSTM Network for Power Quality Disturbance Classification by Shuangquan Yang, Tao Shan, Xiaomei Yang

“…The robustness provided by the DWT module makes the model well suited for PQDs in environments with large disturbances, helping to detect and mitigate PQDs in a timely manner and ultimately contributing to improved power quality and system reliability.…”
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Natural Cyclic Peptides: Synthetic Strategies and Biomedical Applications by Devan Buchanan, Shogo Mori, Ahmed Chadli, Siva S. Panda

“…These compounds are employed in diverse roles, including antibiotics, antifungals, antiparasitics, immune modulators, and anti-inflammatory agents. Their unique ability to combine high specificity with desirable pharmacokinetic properties makes them valuable tools in addressing unmet medical needs, such as combating drug-resistant pathogens and targeting challenging biological pathways. …”
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Hsp90 mutants with distinct defects provide novel insights into cochaperone regulation of the folding cycle. by Rebecca Mercier, Danielle Yama, Paul LaPointe, Jill L Johnson

“…Further analysis will help elucidate additional steps required for progression through the Hsp90 folding cycle and may lead to new strategies for modulating Hsp90 function.…”
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Unveiling cell-type-specific microRNA networks through alternative polyadenylation in glioblastoma by Mert Cihan, Greta Schmauck, Maximilian Sprang, Miguel A. Andrade-Navarro

“…This study focuses on exploring the distinct cellular transitions in GBM, emphasizing the role of alternative polyadenylation (APA) in modulating microRNA-binding and post-transcriptional regulation. …”
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