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7901
Sentimentally enhanced conversation recommender system
Published 2025-01-01“…Furthermore, the responses generated by the dialogue module are often monotonous, lacking diversity and expressiveness, and thus fall short of meeting the demands of complex scenarios. …”
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7902
Characterization of Chromatin Structure-associated Histone Modifications in Breast Cancer Cells
Published 2012-09-01“…Chromatin structure and dynamics that are influenced by epigenetic marks, such as histone modification and DNA methylation, play a crucial role in modulating gene transcription. To understand the relationship between histone modifications and regulatory elements in breast cancer cells, we compared our chromatin immunoprecipitation sequencing (ChIP-Seq) histone modification patterns for histone H3K4me1, H3K4me3, H3K9/16ac, and H3K27me3 in MCF-7 cells with publicly available formaldehyde-assisted isolation of regulatory elements (FAIRE)-chip signals in human chromosomes 8, 11, and 12, identified by a method called FAIRE. …”
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7903
Bone marrow mesenchymal stem cell‐derived exosomes improve renal fibrosis by reducing the polarisation of M1 and M2 macrophages through the activation of EP2 receptors
Published 2022-02-01“…Here, we investigate the therapeutic effect of BM‐MSCs on unilateral ureteral occlusion (UUO)‐induced interstitial fibrosis in the kidney by modulating prostaglandin E2 receptor 2 (EP2). Renal pathological changes were evident in the UUO group compared to the control group, with significantly increased expression of α‐smooth muscle actin (α‐SMA), fibronectin, Ep2 and F4/80+CD86+ and F4/80+CD206+ cells in the UUO group (p< 0.05). …”
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7904
The Effect of Transobturator Tape Surgery on Female Sexual Functions: A Systematic Review
Published 2020-08-01“…In total, 8 clinical studies employed female sexual function index whereas 8 clinical studies administered Prolapse/Urinary Incontinence Sexual Questionnaire -12. 4 of these studies tried to understand women’s sexual functions through questions determined by the researchers (N/A). 2 of the other studies used the Sexual Impact Questionnaire and a visual analogue scale, 1 study used Nine Questions on Sexual Functioning (NSF-9) and 1 study used International Consultation on Incontinence Questionnaire Vaginal Symptoms Module (ICIQ-VS). It was found that transobturator tape surgery that is performed for incontinence produces positive results on both sexual functions and urinary functions. …”
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7905
The Effect of Therapeutic Blockades of Dust Particles-Induced Ca2+ Signaling and Proinflammatory Cytokine IL-8 in Human Bronchial Epithelial Cells
Published 2015-01-01“…We investigated how to modulate dust particles-induced Ca2+ signaling and proinflammatory cytokine IL-8 expression. …”
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7906
An efficient and lightweight detection method for stranded elastic needle defects in complex industrial environments using VEE-YOLO
Published 2025-01-01“…Firstly, GSConv was introduced to enhance feature extraction in depthwise separable convolution and establish the VOVGSCSP module, emphasizing feature reusability for more effective feature engineering. …”
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7907
Sustainable Nutritional Strategies for Gut Health in Weaned Pigs: The Role of Reduced Dietary Crude Protein, Organic Acids and Butyrate Production
Published 2024-12-01“…Butyrate strengthens intestinal barrier integrity by upregulating tight junction proteins, reduces inflammation by modulating cytokine responses, and promotes anaerobic microbial stability. …”
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7908
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7909
HDN-DDI: a novel framework for predicting drug-drug interactions using hierarchical molecular graphs and enhanced dual-view representation learning
Published 2025-01-01“…HDN-DDI integrates an explainable substructure extraction module to decompose drug molecules and represents them using innovative hierarchical molecular graphs, which effectively incorporates information from real chemical substructures and improves molecules encoding efficiency. …”
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7910
LINC00707 Regulates miR-382-5p/VEGFA Pathway to Enhance Cervical Cancer Progression
Published 2021-01-01“…Then, we predicted that LINC00707 could serve as a molecular sponge for miR-382-5p to modulate VEGFA expression in cervical cancer. Subsequently, lack of VEGFA expression reversed the influence of miR-382-5p knockdown on cervical cancer cells. …”
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7911
Experimental and numerical investigation into pile spacing effects on the dynamic response of coastal pile foundation bridges considering current-wave-earthquake forces
Published 2025-01-01“…The analysis also highlighted the critical role of water depth, current velocity, and wave properties in modulating the dynamic response. Complementary 3D numerical models were developed using the Finite Element DIANA Software, and the numerical results closely matched the experimental findings, thereby validating the model’s accuracy. …”
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7912
Network Pharmacology Analysis and Experimental Validation to Explore the Anti-inflammatory Mechanism of Asiatic Acid on Alcoholic Steatohepatitis
Published 2022-01-01“…This study provides multiple lines of evidence that asiatic acid may alleviate alcoholic hepatitis in mice by modulating the NF-κB pathway.…”
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7913
Smart Health Monitoring and Management System for Organizations Using Radio-Frequency Identification (RFID) Technology in Hospitals or Emergency Applications
Published 2022-01-01“…Because the proposed solution is based on mature existing hardware modules and software packages, any experienced information technology professional can quickly build an analogous monitoring and management system by following the instructions presented in this paper.…”
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7914
AFF-LightNet: A Lightweight Ship Detection Architecture Based on Attentional Feature Fusion
Published 2024-12-01“…To enhance the fusion of multi-scale features and semantically inconsistent features, we introduce iterative attentional feature fusion (IAFF) into the proposed neck network, improving the efficiency of feature fusion by introducing a multi-scale channel attention module. Also, deep and cross network version 2 (DCNv2) is replaced by Convolution (Conv) in the backbone network to further improve the detection accuracy of the proposed network. …”
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7915
Advancing Neuroscience and Therapy: Insights into Genetic and Non-Genetic Neuromodulation Approaches
Published 2025-01-01“…By systematically evaluating the principles, mechanisms, advantages, limitations, and efficacy in modulating neuronal activity and the potential applications in interventions of neurological disorders of these neuromodulation techniques, a comprehensive picture is gradually emerging regarding the advantages and challenges of neuromodulation techniques, their developmental trajectory, and their potential clinical applications. …”
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7916
Sliding-Window Dissimilarity Cross-Attention for Near-Real-Time Building Change Detection
Published 2025-01-01“…Subsequently, we integrate an SWDCA module into this backbone, forming an efficient change detection network. …”
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7917
Luteolin ameliorates rat model of metabolic syndrome-induced cardiac injury by apoptosis suppression and autophagy promotion via NR4A2/p53 regulation
Published 2025-01-01“…It is documented that the nuclear receptor 4A2 (NR4A2) could modulate autophagy and apoptosis in cardiac complications. …”
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7918
High-Power MHz to 100s of GHz Circuits and Systems for Nuclear Fusion Reactors With Examples From SST-1 and ITER
Published 2024-01-01“…They launch TEM, TE10, and HE11 modes to rapidly fluctuating plasma loads through various antenna modules with real-time matching, positioning, and beam steering capabilities. …”
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7919
Identification and Validation of TEAD Family’s Prognostic Effects and Immune Microenvironment Regulations in Glioma
Published 2024-01-01“…Importantly, this study discovered that TEADs influence the immunological milieu of glioma by modulating genes associated with immune infiltration.…”
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7920
Quantum-Ordering Ambiguities in Weak Chern—Simons 4D Gravity and Metastability of the Condensate-Induced Inflation
Published 2025-01-01“…Finally, we examine the role of periodic modulations in the axion potential induced by non-perturbative effects on the slow-roll inflationary parameters, and find compatibility with the cosmological data.…”
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