PIWI proteins and piRNAs: key regulators of stem cell biology by Fernando Claro-Linares, Patricia Rojas-Ríos

“…Precisely, in GSCs, PIWI proteins and piRNAs regulate gene expression by modulating chromatin states and directly influencing mRNA translation. …”
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A geometrical optimisation of a coplanar micro-electrode structure for microfluidic flow cytometry by Van Phu Nguyen, Van-Anh Bui, Thu Hang Nguyen, Van Thanh Pham, Thi Thanh Thuy Dang, Quang Loc Do

“…The functionality of the sensing structure was validated using COMSOL Multiphysics, with the Electric Current module defining scalar electric potential within the 3D model. …”
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Significance of the modular approach for independent work of students when studying grammar of a foreign language at non-language university by Yuliya S. Elagina, Kseniya S. Oparina

“…The authors of this article consider the modular approach as a technology in which the content is divided into several units or modules, each of which is studied separately. The study is based on qualitative and quantitative methods, as well as an experiment in teaching. …”
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The bacterial response regulator ArcA uses a diverse binding site architecture to regulate carbon oxidation globally. by Dan M Park, Md Sohail Akhtar, Aseem Z Ansari, Robert Landick, Patricia J Kiley

“…DNase I footprinting assays suggest that non-canonical arrangements of cis-regulatory modules dictate both the length and concentration-sensitive occupancy of DNA sites. …”
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MicroRNA-219 in the central nervous system: a potential theranostic approach by Nahal Shamaeizadeh, Mina Mirian

“…Furthermore, miR-219 also plays a role in modulating tau toxicity, which is relevant to the pathophysiology of Alzheimer’s disease and schizophrenia. …”
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Surface defect detection on industrial drum rollers: Using enhanced YOLOv8n and structured light for accurate inspection. by Guofeng Qin, Qinkai Zou, Mengyan Li, Yi Deng, Peiwen Mi, Yongjian Zhu, Hao Liu

“…Then, a new feature fusion module was proposed to enable the fusion network to learn additional original information. …”
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Exploring the impact of telemedicine in chronic patients from diverse socioeconomic contexts: systematic review of qualitative studies by Yuzhe Li, Qifang Shi, Jing Yang, Li Ran

“…We should actively solve the problems and maximize the functions of telemedicine.ObjectiveTo explore the application and improvement of telemedicine in chronic disease self-management to provide important insights from functional module analysis for stakeholders, healthcare professionals, and policymakers to promote the development of telemedicine in chronic disease management.DesignWe conducted a systematic review and qualitative synthesis of five English databases including PubMed, Embase, Web of Science, Cochrane Database of Systematic Reviews, and Scopus, as well as three Chinese databases: China National Knowledge Infrastructure (CNKI), WanFang and VIP database. …”
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Liver Fibrosis and Altered Matrix Synthesis by Katrin Neubauer, Bernhard Saile, Giuliano Ramadori

“…A number of substances are currently being tested that either neutralize fibrogenic stimuli and prevent the activation of hepatic stellate cells, or directly modulate the matrix metabolism. However, until now, the elimination of the hepatotoxins has been the sole therapeutic concept available for the treatment of liver fibrogenesis in humans.…”
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Impact of Isothermal Layering on the Stability of Saline Soil Subgrade in Cold Regions by Yu Zhang, Xuerui Chen, Meisi Zou, Runze Tian, Yunlong Hou, Bingbing Han

“…Secondly, combined with the main strength parameters of subgrade soil at different temperatures, an isothermal stratification-strength parameter function calculation model was proposed. Then, the SLOPE/W module in GeoStudio is used to stratify the established subgrade model according to isotherms and calculate the stability safety factor of saline soil subgrades in cold regions under different months, slopes, and subgrade heights, respectively. …”
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Development of an information measuring and control system for a quadrocopter by V. V. Sleptsov, V. L. Afonin, A. E. Ablaeva, Ba Phuong Dinh

“…The main sensors and modules used to determine the parameters of the coordinates of quadrocopters are given. …”
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Perception of vocoded speech in domestic dogs by Amritha Mallikarjun, Emily Shroads, Rochelle S. Newman

“…Noise-vocoded speech is made by dividing the speech signal into frequency bands (channels), identifying the amplitude envelope of each individual band, and then using these envelopes to modulate bands of noise centered over the same frequency regions – the result is a signal with preserved temporal cues, but vastly reduced frequency information. …”
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Rain removal method for single image of dual-branch joint network based on sparse transformer by Fangfang Qin, Zongpu Jia, Xiaoyan Pang, Shan Zhao

“…Finally, the parallel dual-branch joint module, composed of RSTB and UEDB branches, effectively captures the local context and global structure, culminating in a clear background image. …”
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Modulatory effects of rutin on the expression of cytochrome P450s and antioxidant enzymes in human hepatoma cells by Karakurt Sedar

“…Expression of a drug and xenobiotic metabolizing enzymes, cytochrome P450s (CYPs), and antioxidant enzymes can be modulated by various factors. The flavonoid rutin was investigated for its anti-carcinogen and protective effects as well as modulatory action on CYPs and phase II enzymes in human hepatocellular carcinoma cells. …”
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Effects of a Single Session of High Intensity Interval Treadmill Training on Corticomotor Excitability following Stroke: Implications for Therapy by Sangeetha Madhavan, James W. Stinear, Neeta Kanekar

“…We also determined whether exercise-induced changes in excitability could be modulated by transcranial direct current stimulation (tDCS) enhanced with a paretic ankle skill acquisition task. …”
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Explainable correlation-based anomaly detection for Industrial Control Systems by Ermiyas Birihanu, Imre Lendák

“…This is achieved through an anomaly detection module that incorporates a threshold mechanism, utilizing alpha and epsilon values. …”
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The Role of the Enterohepatic Circulation of Bile Salts and Nuclear Hormone Receptors in the Regulation of Cholesterol Homeostasis: Bile Salts as Ligands for Nuclear Hormone Recept... by Richard N Redinger

“…Pharmacologically targeted receptor agonists (or antagonists) may be developed that alter cholesterol and bile salt concentrations by modulating nuclear hormone receptors and/or their coactivators or corepressors to positively affect cholesterol homeostasis and bile salt metabolism. …”
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Marital adjustment and quality of life among HIV discordant couples by Subhasis Bhadra, Nupur Tayal

“…HIV is still a glo­bal epidemic with number of treatment module, yet there is no vaccine to prevent. Number of efforts made by the World Health Organization, National Governments and humanitarian organizations to spread awareness and provide support. …”
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Structural basis for c-di-GMP-mediated inside-out signaling controlling periplasmic proteolysis. by Marcos V A S Navarro, Peter D Newell, Petya V Krasteva, Debashree Chatterjee, Dean R Madden, George A O'Toole, Holger Sondermann

“…In the absence of c-di-GMP, the intracellular module assumes an inactive conformation. Binding of c-di-GMP to the phosphodiesterase domain disrupts the inactive state, permitting the formation of a trans-subunit dimer interface between adjacent phosphodiesterase domains via interactions conserved in c-di-GMP-degrading enzymes. …”
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Differentially Expressed Genes Study Shown Potential for BCG Stimulation in Reducing the Severity of COVID-19 by Irandi Putra Pratomo, Aryo Tedjo, Dimas R Noor, Wisnu Ananta Kusuma

“…In this study, we used a differentially expressed genes (DEG) approach to analyze the genes modulated by BCG vaccination and COVID-19 infection. …”
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Optimization of Online Course Content According to Users Activity Statistics by V. A. Starodubtsev, О. В. Lobanenko, О. V. Sitnikova

“…Optimization of the learning process with the use of online course requires designing of a course with week module structure and singled out micro-targets. The learning material should be presented in various formats taking into account students’ preference for infographics. …”
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