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7681
Ontogeny and function of the intestinal epithelial and innate immune cells during early development of chicks: to explore in ovo immunomodulatory nutrition
Published 2025-01-01“…Thus, summarizing the ontogeny and function of IECs, innate immunity systems, and interaction mechanisms of in ovo feeding of bioactive substances could provide baseline information for designing targeted in ovo feeding interventions to modulate cell waise specific innate immune systems.…”
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7682
Why the brown ghost chirps at night
Published 2025-01-01“…These are mainly characterized by brief frequency modulations of the oscillating dipole moment continuously generated by their electric organ, and are known as chirps. …”
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7683
An Improved Method for Enhancing the Accuracy and Speed of Dynamic Object Detection Based on YOLOv8s
Published 2024-12-01“…Specifically, a Focused Linear Attention mechanism is introduced into the YOLOv8s backbone network to enhance dynamic object detection accuracy, while the Ghost module is incorporated into the neck network to improve the model’s tracking speed for dynamic objects. …”
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7684
LotusSQL: SQL Engine for High-Performance Big Data Systems
Published 2021-12-01“…In recent years, Apache Spark has become the de facto standard for big data processing. SparkSQL is a module offering support for relational analysis on Spark with Structured Query Language (SQL). …”
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7685
Beyond metabolic messengers: Bile acids and TGR5 as pharmacotherapeutic intervention for psychiatric disorders
Published 2025-01-01“…Importantly, we detail both pharmacological and non-pharmacological interventions that modulate TGR5 signaling, offering potential breakthroughs in treatment strategies. …”
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7686
Modular Multi‐Parametric and Portable Readout System for Point‐of‐Care Applications
Published 2025-01-01“…Combined optical and thermal readout for spectroscopy is implemented by installing two different analog front‐end modules in the four input channels equipped with a micro spectrometer and a high‐resolution temperature sensor, respectively. …”
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7687
Intelligent characterization of ultra-deep carbonate strike-slip fault zones based on 3DResNeSt-UNet: a case study of the YueMan Block in the Tarim Basin
Published 2025-01-01“…This network integrates the 3DUNet and ResNeSt modules, using synthetic 3D seismic data and its corresponding label data as inputs for training. …”
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7688
Deacetylated SNAP47 recruits HOPS to facilitate autophagosome-lysosome fusion independent of STX17
Published 2025-01-01“…Taken together, our study uncovers a SNAP47 acetylation-dependent regulatory mechanism governing autophagosome-lysosome fusion by modulating the recruitment of HOPS to autophagic vacuoles without involving STX17, SNAP47-STX17 interaction and ternary SNARE complex formation.…”
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7689
Remediation Effects on N170 and P300 in Children with Developmental Dyslexia
Published 2010-01-01“…We argue that training might modulate cortical activity in dyslexic children in a visual word recognition task. …”
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7690
Plant-nanoparticles enhance anti-PD-L1 efficacy by shaping human commensal microbiota metabolites
Published 2025-02-01“…Our findings reveal a previously unknown mechanistic impact of PNP on human tumor immunotherapy by modulating gut bacterial metabolic pathways.…”
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7691
Mesenchymal Stem Cell Therapy for Cardiac Inflammation: Immunomodulatory Properties and the Influence of Toll-Like Receptors
Published 2013-01-01“…This happens likely via a paracrine mechanism. As MSC are potent modulators of the immune system, this could influence this postinfarct immune response. …”
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7692
Employing the Oncolytic Vesicular Stomatitis Virus in Cancer Virotherapy: Resistance and Clinical Considerations
Published 2024-12-01“…Strategies to overcome resistance include enhancing viral oncoselectivity, inhibiting IFN responses, modulating the TME, and combining VSV with chemotherapies, radiation, and immune checkpoint inhibitors. …”
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7693
CRISPR screen reveals modifiers of rAAV production including known rAAV infection genes playing an unexpected role in vector production
Published 2025-03-01“…Specifically, we performed a CRISPR-based genome-wide knockout (KO) screen in human embryonic kidney (HEK) 293 cells using an antibody specific to intact AAV2 capsids coupled with flow cytometry to identify genes that modulate rAAV production. We discovered that the KO of a group of heparan sulfate biosynthesis genes previously implicated in rAAV infectivity decreased rAAV production. …”
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7694
A Modular and Scalable Approach to Hybrid Battery and Converter Integration for Full-Electric Waterborne Transport
Published 2025-01-01“…This real-time capability has been validated, and related results are presented in this paper, showing a synchronization accuracy below 200 ns between two modules and a stable control at a cycle time of 400 µs. …”
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7695
Modified SWAT Model for Agricultural Watershed in Karst Area of Southwest China
Published 2025-01-01“…This study aims to refine the delineation of hydrological response units within the SWAT model by combining geomorphological classification and to enhance the model with an epikarst zone hydrological process module, exploring the accuracy improvement of SWAT model simulations in karst regions of Southwest China. …”
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7696
Neuroprotective Effects of Myrtle Berry By-Product Extracts on 6-OHDA-Induced Cytotoxicity in PC12 Cells
Published 2025-01-01“…Our findings reveal that Myrtus extract significantly protects against 6-OHDA-induced cytotoxicity, reduces ROS levels, and modulates the expression of key stress-related genes, underscoring its potential as a neuroprotective agent. …”
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7697
Context-Aware Fine-Grained Product Recognition on Grocery Shelves
Published 2025-01-01“…Second, we propose the Context-Aware Query Expansion (CAQE) module for the inference phase, in which each feature vector of a product on a shelf is expanded with the feature vectors of neighboring products. …”
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7698
Epigenetic modifications and emerging therapeutic targets in cardiovascular aging and diseases
Published 2025-01-01“…The complex mechanisms underlying the development of cardiovascular diseases remain not fully elucidated. Epigenetics, which modulates gene expression without DNA sequence changes, is shedding light on these mechanisms and their heritable effects. …”
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7699
Control System for U-Arm Robot Arm Movement with Linear Gripper Based on Inverse Kinematic Method
Published 2024-12-01“…The robotic arm consists of four links with lengths of 8.2 cm, 15 cm, 16 cm, and 18.4 cm, respectively, and is equipped with a gripping module for object manipulation. The methodology involves calculating the joint angles required for the desired end-effector position, ensuring accurate and efficient movement. …”
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7700
Motor Sequence Learning across Multiple Sessions Is Not Facilitated by Targeting Consolidation with Posttraining tDCS in Patients with Progressive Multiple Sclerosis
Published 2021-01-01“…While task performance across blocks of training and across sessions improved significantly in both the active and sham tDCS experiment, neither online nor offline motor learning was modulated by the type of tDCS. Accordingly, the primary endpoint (task performance on day 8) did not differ between stimulation conditions. …”
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