Increased Frequency of Circulating Follicular Helper T Cells in Children with Hand, Foot, and Mouth Disease Caused by Enterovirus 71 Infection by Jianping Wu, David Cui, Xianzhi Yang, Jianzhou Lou, Jie Lin, Xianfei Ye, Zhimei Qin, Li Huang, Dejian Zhao, Zhaoxia Huo, Guoliang Xie, Shufa Zheng, Fei Yu, Liwei Lu, Yu Chen

“…These data indicate a role of TFH cells and associated cytokines in modulating the humoral response during the pathogenesis of EV71 infection.…”
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Important Citation Identification by Exploding the Sentiment Analysis and Section-Wise In-Text Citation Weights by Shahzad Nazir, Muhammad Asif, Shahbaz Ahmad, Hanan Aljuaid, Rimsha Iftikhar, Zubair Nawaz, Yazeed Yasin Ghadi

“…In this research work, we proposed an approach based on two primary modules, 1) The section-wise citation count and 2) Sentiment based analysis of citation sentences. …”
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Unlocking the secrets of the immunopeptidome: MHC molecules, ncRNA peptides, and vesicles in immune response by Arpita Balakrishnan, Arpita Balakrishnan, Gabriela Winiarek, Olga Hołówka, Jakub Godlewski, Agnieszka Bronisz

“…The article highlights novel research on non-coding RNA (ncRNA)-derived peptides, which challenge conventional views of antigen processing and presentation and the role of EVs in transporting these peptides, thereby modulating immune responses at remote body sites. This novel research not only challenges conventional views but also opens up new avenues for understanding immune responses. …”
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A cryo-shocked M2 macrophages based treatment strategy promoting repair of spinal cord injury via immunomodulation and axonal regeneration effects by Ermei Lu, Kecheng Zhou, Jiansen Miao, Yanlin Zhu, Jiyao Tang, Siting Du, Yanzhen Feng, Linyuan Jiang, Tianyao Jiang, Ting Huang, Ping Li, Xinjun Miao, Qi Han, Jian Xiao

“…The LNT M2-based dual-functional scaffold significantly enhances motor function, reduces neuroinflammation, and accelerates axonal regeneration by modulating the inflammatory microenvironment and preventing the formation of glial and fibrotic scars. …”
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Ligand-tuning copper in coordination polymers for efficient electrochemical C–C coupling by Yu Yang, Cheng Zhang, Chengyi Zhang, Yaohui Shi, Jun Li, Bernt Johannessen, Yongxiang Liang, Shuzhen Zhang, Qiang Song, Haowei Zhang, Jialei Huang, Jingwen Ke, Lei Zhang, Qingqing Song, Jianrong Zeng, Ying Zhang, Zhigang Geng, Pu-Sheng Wang, Ziyun Wang, Jie Zeng, Fengwang Li

“…Electronic structure modelling, X-ray absorption spectroscopy, and ultraviolet–visible spectroscopy show a widely tuneable Cu electronics by modulating the highest occupied molecular orbital energy of ligands. …”
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Insight into landscape characteristics influence on the adaptability of estuarine shallow groundwater system to 100-year extreme precipitation by Qian Zheng, Fubin Luo, De Wang

“…Landscape characteristics, particularly the combination of artificial and natural waterways, regulate the differences in groundwater responses among the four patterns by modulating three types of groundwater-precipitation relationships. …”
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Probabilistic forecasting of renewable energy and electricity demand using Graph-based Denoising Diffusion Probabilistic Model by Amir Miraki, Pekka Parviainen, Reza Arghandeh

“…Our framework employs a parallel feature extraction module that simultaneously captures temporal dynamics and spatial correlations, enabling improved forecasting accuracy. …”
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Lightweight marine biodetection model based on improved YOLOv10 by Wei Pan, Jiabao Chen, Bangjun Lv, Likun Peng

“…Additionally, the model incorporates the DysnakeConv module within the C2f structure to enhance feature extraction, along with the Powerful-IOU (PIOU) loss function for better data fitting. …”
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Social media network public opinion emotion classification method based on multi-feature fusion and multi-scale hybrid neural network by Yuan Yao, Xi Chen, Peng Zhang

“…An in-depth analysis addresses the label drift phenomenon between aspect term words, and a position-aware module is constructed to mitigate the local development plan (LDP) issue.…”
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Systematic Characterization of Splicing Dysregulation in Pan Solid Tumor Transcriptome by Jingru Sui, Dan Guo, Xiao Wen, Lei Zhou, Yue Huang, Haoyu Yu, Jinyu Chen, Zhaoqi Liu

“…Six unique patterns illustrated by ASE‐SF co‐modules are summarized, which involve 1,570 ASEs and altered expression of 170 SFs, covering 40% of TCGA solid tumors. …”
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Restoration of Central Programmed Movement Pattern by Temporal Electrical Stimulation-Assisted Training in Patients with Spinal Cerebellar Atrophy by Ying-Zu Huang, Yao-Shun Chang, Miao-Ju Hsu, Alice M. K. Wong, Ya-Ju Chang

“…Since peripheral electrical stimulation (ES) and motor training may modulate motor cortical excitability through plasticity mechanisms, we aimed to investigate whether temporal ES-assisted movement training could influence premovement cortical excitability and alleviate hypermetria in patients with spinal cerebellar ataxia (SCA). …”
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Neural Correlates of Dual-Task Walking: Effects of Cognitive versus Motor Interference in Young Adults by Rainer Beurskens, Fabian Steinberg, Franziska Antoniewicz, Wanja Wolff, Urs Granacher

“…Average activity in alpha and beta frequencies was significantly modulated during both CI and MI walking conditions in frontal and central brain regions, indicating an increased cognitive load during dual-task walking. …”
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PPAR-γ Regulates Trophoblast Differentiation in the BeWo Cell Model by Khrystyna Levytska, Sascha Drewlo, Dora Baczyk, John Kingdom

“…Here, we aimed to characterize the baseline activity of PPAR-γ in the human choriocarcinoma BeWo cell line that mimics SCT formation in vitro and modulate PPAR-γ activity to study its effects on cell proliferation versus differentiation. …”
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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM. by Frances M Bashore, Vittorio L Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J Bradshaw, Karolina A Rygiel, Tina M Leisner, Rod Chalk, Swati Mishra, C Andrew Williams, Opher Gileadi, Paul E Brennan, Jesse C Wiley, Jake Gockley, Gregory A Cary, Gregory W Carter, Jessica E Young, Kenneth H Pearce, Haian Fu, Emory-Sage-SGC TREAT-AD Center, Alison D Axtman

“…RNA sequencing and genetic data support spleen tyrosine kinase (SYK) and high affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) as putative targets to be modulated for Alzheimer's disease (AD) therapy. FCER1G is a component of Fc receptor complexes that contain an immunoreceptor tyrosine-based activation motif (ITAM). …”
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PKCα regulates the secretion of PDL1-carrying small extracellular vesicles in a p53-dependent manner by Ren Zhang, Weilin Liao, Xi Chen, Junyi Wang, Jiaqi Li, Geer Chen, Weiyu Wu, Xiaoxuan Wang, Yao Zhang, Ziyu Chen, Xiaoyu Zhu, Zicong Lin, Yizhun Zhu, Lijuan Ma, Haijie Yu

“…Our findings suggest that targeting PKCα to modulate PD-L1 dynamics in NSCLC may be a promising therapeutic strategy to enhance the efficacy of immunotherapeutic interventions.…”
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Chitosan as an Immunomodulating Adjuvant on T-Cells and Antigen-Presenting Cells in Herpes Simplex Virus Type 1 Infection by Bunsoon Choi, Do-Hyun Jo, A. K. M. Mostafa Anower, S. M. Shamsul Islam, Seonghyang Sohn

“…These results suggest that chitosan is a potential modulator or immune stimulator as an adjuvant in HSV-1 infected mice.…”
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Evaluating the Efficacy of Transoral Robotic Surgery (TORS) Versus Radiotherapy, Chemotherapy, and Open Surgery in Treating Oropharyngeal Squamous Cell Carcinoma (OPSCC): A Systema... by Abdulrhman Alsayeg, Maha Naif Alshammari, Abdulrahman Mesfer Alajmi, Reem Faihan Alotaibi

“…In this study, we investigate the use of TORS in the management of OPSCC and compare it with intensity-modulated radiation therapy (IMRT), concurrent chemoradiation therapy (CCRT), and open surgery. …”
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New Insights into the PPARγ Agonists for the Treatment of Diabetic Nephropathy by Zhanjun Jia, Ying Sun, Guangrui Yang, Aihua Zhang, Songming Huang, Kristina Marie Heiney, Yue Zhang

“…Recently, numerous novel PPARγ agonists involving the endogenous PPARγ ligands and selective PPARγ modulators (SPPARMs) are emerging as the promising candidates of the next generation of antidiabetic drugs instead of TZDs. …”
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Case report: A rare case of a long-term survivor of glioblastoma who underwent two courses of hypofractionated radiotherapy as part of her care by Midhad Mrvoljak, Midhad Mrvoljak, Shubhendu Mishra, Liam Chen, Liam Chen, Elizabeth Neil, Elizabeth Neil, Eric Ehler, Stephanie Terezakis, Stephanie Terezakis, Lindsey Sloan, Lindsey Sloan

“…The patient is a 75-year-old woman who presented with progressive aphasia and was diagnosed with GB (WHO grade 4, IDH1/IDH2 wild type, ATRX intact, p53 and PTEN mutant, BRAF non-mutated, O6-methylguanine-DNA methyltransferase promoter methylated) and who underwent surgical resection, hypofractionated radiotherapy (HFRT) using intensity-modulated radiotherapy (IMRT) (4,005 cGy in 15 fractions) alone, and adjuvant temozolomide (TMZ). …”
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When the days are(n’t) numbered: Calendar calculations in transparent and opaque systems by Ziyi Zhuang, Norbert Vanek

“…These findings bring new evidence for linguistic relativity in the form of modulations of calendar processing speed changing as a function of linguistic transparency, input type and task demand.…”
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