Lung-specific CRBN knockout attenuates influenza a virus-induced acute lung injury in mice: a potential therapeutic approach by Lifang Zhang, Qingchao Zhang, Jiahui Chang, Yunyi Zhou, Wei Wang, Xiliang Wang, Chengyu Jiang, Yanli Zhang

“…Collectively, these findings indicate that CRBN plays a pivotal role in the pathogenesis of influenza-induced lung injury by modulating MAPK pathway signaling, underscoring its therapeutic potential as a target for intervention.…”
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Protective Effect of Vitamins C and E on Depot-Medroxyprogesterone Acetate-Induced Ovarian Oxidative Stress In Vivo by Atik Ismiyati, I. Wayan Arsana Wiyasa, Dwi Yuni Nur Hidayati

“…Combined vitamins C and E prohibit the increase in ovarian lipid peroxidation, at least in part by modulating of superoxide dismutase. Therefore, this may provide an antioxidant therapy for attenuating the ovarian toxicity found in the DMPA therapy.…”
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Lifelong Learning in the System of Higher Education: the State of the Problem and the Strategy of Integrating Educational Activities and Research by A. V. Keller, I. A. Korshunov, N. N. Shirkova, G. N. Suvorov, E. S. Szhenov, S. S. Shadrin, A. A. Orekhov

“…The authors consider, how universities can be focused on working with the population or industry enterprises, integrating the research results into the modules of education programs, and stimulating an increase in the number of teachers combining research and teaching activities, at realizing the third University’s mission and taking into account the research grant volume.…”
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Techno-Economic Analysis of Waste Heat Recovery in Automotive Manufacturing Plants by Putu Diah Prajna Paramita, Sindu Daniarta, Attila R. Imre, Piotr Kolasiński

“…This study proposes an innovative system for recovering waste heat from exhaust air after a regenerative thermal oxidiser process, integrating a Carnot battery and photovoltaic (PV) modules. The Carnot battery incorporates an organic Rankine cycle (ORC) with a recuperator, thermal energy storage (TES), and heat pump. …”
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Shielding the Gut: Ghrelin and Ferrostatin-1’s Protective Role Against Sepsis-Induced Intestinal Ferroptosis by Qiliang Hou, Zhimin Dou, Lei Zhu, Bin Li

“…Both interventions restored intestinal barrier functions, modulated inflammatory responses, and attenuated oxidative stress, indicating a suppression of the ferroptosis pathway. …”
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Reliability-Based Optimum Design of Dome Truss Structures through Enhanced Vibration Particle System by Pedram Hosseini, Nasibeh Hatami, Seyed Rohollah Hoseini Vaez

“…Throughout this study, random variables such as the module of elasticity, material density, and the cross-sectional area of the elements are considered. …”
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Correlation between Serum Osteopontin and miR-181a Levels in Allergic Rhinitis Children by Wenlong Liu, Qingxiang Zeng, Renzhong Luo

“…The OPN protein and miR-181a levels may serve as predictors of disease severity in childhood AR and appear to be promising targets for modulating AR.…”
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Case report: A case of type 1 diabetes with diabetic ketoacidosis induced by envafolimab treatment in hepatocellular carcinoma by Youjia Li, Kai Qu, Xiuli Li, Xin Yang, Kanghuai Zhang, Jiao Xie

“…Notably, the absence of diabetes-related autoantibodies suggests that the diabetes was induced by the immune-modulating effects of Envafolimab rather than a pre-existing autoimmune condition. …”
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Loader Bucket Working Angle Identification Method Based on YOLOv5s and EMA Attention Mechanism by Xuedong Zhang, Bo Cui, Zhaoxu Wang, Wangting Zeng

“…Subsequently, Depth Separable Convolution was employed to replace the standard convolution in the C3 module of the Backbone, improving the model’s accuracy in identifying target deformation caused by changes in the bucket angle, reducing the computational load, and enhancing the model’s operational speed. …”
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Dynamic Warping Network for Semantic Video Segmentation by Jiangyun Li, Yikai Zhao, Xingjian He, Xinxin Zhu, Jing Liu

“…Firstly, we design a flow refinement module (FRM) to optimize the precomputed optical flow. …”
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In situ evaluation and manipulation of lithium plating morphology enabling safe and long‐life lithium‐ion batteries by Shuoyuan Mao, Yu Wang, Yao Lu, Xuebing Han, Yuejiu Zheng, Xuning Feng, Xinqi Ren, Languang Lu, Minggao Ouyang

“…Abstract The morphology of plated lithium (MPL) metal on graphite anodes, traditionally described as “moss‐like” and “dendrite‐like”, exert a substantial negative influence on the performance of lithium‐ion batteries (LIBs) by modulating the metal‐electrolyte interface and side reaction rates. …”
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Evidence That ADAM17 Mediates the Protective Action of CGRP against Angiotensin II-Induced Inflammation in Vascular Smooth Muscle Cells by Si-yu Zeng, Li Yang, Chen-liang Hong, Hui-qin Lu, Qiu-jiang Yan, Yan Chen, Xu-ping Qin

“…This study is aimed at determining the anti-inflammatory effect of CGRP in Ang II-treated VSMCs and whether a disintegrin and metalloproteinase 17 (ADAM17) modulates this protective action. Small interference RNA (siRNA) and inhibitors of CGRP, epidermal growth factor receptor (EGFR), and extracellular signal-regulated kinase 1/2 (ERK1/2) were adopted to investigate their effect on Ang II-induced inflammation in VSMCs. …”
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The Link Between Gut Microbiota and Depression: Exploring the Correlation by Adam Juśkiewicz, Olga Grelewicz, Natalia Kucy, Elwira Servaas, Mateusz Haber, Paula Kula, Adrianna Czachor, Alicja Kotula

“…Probiotics, prebiotics, dietary modifications, and fecal microbiota transplantation (FMT) represent diverse interventions aimed at restoring microbial balance, modulating gut-brain communication, and reducing neuroinflammation associated with depression. …”
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A novel case of glial transdifferentiation in renal medullary carcinoma brain metastasis by Maria A. Gubbiotti, Ian E. McCutcheon, Priya Rao, Giannicola Genovese, Linghua Wang, Artem Tarasov, Vladislav Putintsev, Amber Berlinski, Danil Stupichev, Kirill Kriukov, Suren Davitavyan, Basim Salem, Alexander Sarachakov, Dmitry Lebedev, Michael Hensley, Alexander Bagaev, Francesca Paradiso, Vladimir Kushnarev, Gleb Khegai, Nizar M. Tannir, Pavlos Msaouel

“…Therefore, given the common genetic signatures in the brain metastasis and the patient’s prior tumor, this case represents a rare event of glial transdifferentiation in a brain metastasis of renal medullary carcinoma following the use of an epigenetic modulator. As renal medullary carcinoma has been known to cleverly utilize adaptive mechanisms for survival, we propose that such cell plasticity seen in this case may have been provoked by the use of a drug that alters the epigenetic signature of the tumor cells. …”
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MicroRNA-155: Regulation of Immune Cells in Sepsis by Ming Chen, Fuquan Wang, Haifa Xia, Shanglong Yao

“…In this review, we summarized how miR-155 modulates specific immune cells and the regulatory role of miR-155 in sepsis. miR-155 is expressed by different populations of innate and adaptive immune cells and is involved in the regulation of development, proliferation, and function in these cells. …”
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Visualization and research methodology of three-dimensional magnetic field of suspended electromagnetic iron separator with typesetting poles and pole tips by A. V. Radchenko, K. I. Nikitin, A. S. Tatevosyan, R. T. Tazhiyev

“…Based on the processing of experimental data the visualization of the spatial distribution of the module and vector-components of magnetic induction and ponderomotive (magnetic) force in Excel are presented. …”
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Controlling Underwater Robots with Electronic Nervous Systems by Joseph Ayers, Nikolai Rulkov, Dan Knudsen, Yong-Bin Kim, Alexander Volkovskii, Allen Selverston

“…We have constructed locomotor central pattern generators (CPGs) with aVLSI networks that can be modulated to select different behaviours on the basis of selective command input. …”
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Age and estrogen-associated reductions in hypoxic ventilatory response and chemosensitivity in female rats by Jessica M. L. Grittner, Rebecca Barok, Edgar Juarez Lopez, Misha Shah, Brendan J. Dougherty

“…Respiratory function is modulated by circulating steroid hormones. In female rats, steroid hormones fluctuate across the normal estrous cycle and decline with age, similar to human menopause. …”
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LncRNA PVT1 links estrogen receptor alpha and the polycomb repressive complex 2 in suppression of pro-apoptotic genes in hormone-responsive breast cancer by Viola Melone, Domenico Palumbo, Luigi Palo, Noemi Brusco, Annamaria Salvati, Antonietta Tarallo, Giorgio Giurato, Francesca Rizzo, Giovanni Nassa, Alessandro Weisz, Roberta Tarallo

“…Functional assays and transcriptome analysis following lncRNA knock-down indicated PVT1 as the master modulator of some of the most relevant BC hallmarks, such as cell proliferation, apoptosis, migration and response to hypoxia. …”
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Research on the generation and annotation method of thin section images of tight oil reservoir based on deep learning by Tao Liu, Zongbao Liu, Kejia Zhang, Chunsheng Li, Yan Zhang, Zihao Mu, Mengning Mu, Mengting Xu, Yue Zhang, Xue Li

“…Then, the SALM annotation module was designed to achieve semi-automatic annotation of the generated images. …”
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