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  1. 7501

    A trend of osteocalcin in diabetes mellitus research: bibliometric and visualization analysis by Zixu Liu, Zixu Liu, Yuchen Mao, Kangping Yang, Shukai Wang, Fang Zou

    Published 2025-01-01
    “…Analysis using the VoS viewer suggests a shift in research focus towards the correlation between osteocalcin levels and diabetic complications, the clinical efficacy of therapeutic agents or vitamins in the treatment of osteoporosis in diabetic patients, and the mechanisms by which osteocalcin modulates insulin action. The proposed focus areas are “osteocalcin genes”, “insulin regulation and osteoporosis “, “different populations”, “diabetes-related complications” and “type 2 diabetes mellitus”,“effect of osteocalcin expression on insulin sensitivity as well as secretion”,“osteocalcin expression in different populations of diabetic patients and treatment-related studies”.…”
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  2. 7502

    Effects of the Glutamine Administration on T Helper Cell Regulation and Inflammatory Response in Obese Mice Complicated with Polymicrobial Sepsis by Chiu-Li Yeh, Li-Han Su, Jin-Ming Wu, Po-Jen Yang, Po-Chu Lee, Po-Da Chen, Chun-Chieh Huang, Der-Yirng Hsieh, Hsueh-Ju Wang, Sung-Ling Yeh, Ming-Tsan Lin

    Published 2020-01-01
    “…These findings suggest that the intravenous administration of GLN to obese mice after sepsis modulated a more balanced Th cell lineage, alleviated inflammation, and attenuated lung injury.…”
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  3. 7503

    Coffee and its Biologically Active Components: Is There a Connection to Breast, Endometrial, and Ovarian Cancer? - a Review by Anna Maria Witkowska, Iwona Mirończuk-Chodakowska, Katarzyna Maria Terlikowska, Kamila Kulesza, Małgorzata Elżbieta Zujko

    Published 2020-05-01
    “…It has been suggested that selected coffee secondary metabolites may beneficially modulate several mechanisms of anti-cancer protection. …”
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    Article
  4. 7504

    Tumor Metastasis to the Liver, and the Roles of Proteinases and Adhesion Molecules: New Concepts from In Vivo Videomicroscopy by Alan C Groom, Ian C MacDonald, Eric E Schmidt, Vincent L Morris, Ann F Chambers

    Published 1999-01-01
    “…Integrin-based interventions can modulate postextravasation cell migration and cell growth. …”
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  5. 7505

    Influence of Electrostatic Interactions on the Self-Assembly of Charged Peptides by Xue Sun, Bolan Wu, Na Li, Bo Liu, Shijun Li, Liang Ma, Hangyu Zhang

    Published 2025-01-01
    “…Furthermore, incorporating materials with varied charging properties into Z5 hydrogels can alter the electrostatic interactions among peptide nanofibers, further modulating the rheological properties and the printability of SAP hydrogels.…”
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  6. 7506

    Uric Acid-Induced Adipocyte Dysfunction Is Attenuated by HO-1 Upregulation: Potential Role of Antioxidant Therapy to Target Obesity by Komal Sodhi, Jordan Hilgefort, George Banks, Chelsea Gilliam, Sarah Stevens, Hayden A. Ansinelli, Morghan Getty, Nader G. Abraham, Joseph I. Shapiro, Zeid Khitan

    Published 2016-01-01
    “…These findings demonstrate that increased levels of HO-1 appear crucial in modulating the phenotype of adipocytes exposed to uric acid and in downregulating XO and NADPH oxidase levels.…”
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  7. 7507

    Marine Automatic Weather System (MAWS) instrumentation system for climate change monitoring based on The Internet of Things (IoT) by Husen Zakaria, Ismail Nazli, Syukri Surbakti Muhammad, Omar Fairuz, Yusibani Elin, Kesuma Fatmawati, Nurhanif Nurhanif, Arif Hasibuan Ahmad, Fauzi Fauzi

    Published 2025-01-01
    “…This instrument is also equipped with a SIM808 GSM/GPRS/GPS module. In this research, there are two stages of equipment testing, i.e. laboratory testing to determine whether data can be sent in real-time into the database, and field testing which functions to calibrate the equipment. …”
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  8. 7508

    Cell Architecture Design for Fast-Charging Lithium-Ion Batteries in Electric Vehicles by Firoozeh Yeganehdoust, Anil Kumar Madikere Raghunatha Reddy, Karim Zaghib

    Published 2025-01-01
    “…Considering the requirements and challenges of high-power charging systems, we examined how modules, packs, and the vehicle chassis should be adapted to provide fast and ultra-fast charging. …”
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  9. 7509

    Pathological roles of ubiquitination and deubiquitination systems in sepsis-induced myocardial dysfunction by Zhiping Wang, Simiao Sun, Lili Huang, Xinlong Chen, Huifen Xu, Hongwei Ma, Mingbing Xiao, Linhua Wang

    Published 2025-01-01
    “…Strategies aimed at modulating E3 ligase activity or restoring DUB balance have shown promise in preclinical studies. …”
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  10. 7510

    Regulation of Ghrelin Receptor by Periodontal Bacteria In Vitro and In Vivo by Marjan Nokhbehsaim, Anna Damanaki, Andressa Vilas Boas Nogueira, Sigrun Eick, Svenja Memmert, Xiaoyan Zhou, Shanika Nanayakkara, Werner Götz, Joni Augusto Cirelli, Andreas Jäger, James Deschner

    Published 2017-01-01
    “…The expression of the functional ghrelin receptor in periodontal cells and tissues is modulated by periodontal bacteria. Due to the downregulation of the functional ghrelin receptor by long-term exposure to periodontal bacteria, the anti-inflammatory actions of ghrelin may be diminished in chronic periodontal infections, which could lead to an enhanced periodontal inflammation and tissue destruction.…”
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  11. 7511

    Nature’s magic: how natural products work hand in hand with mitochondria to treat stroke by Lin Cheng, Shangbin Lv, Chengkai Wei, Sucheng Li, Hao Liu, Yong Chen, Zhaoliang Luo, Hongyan Cui

    Published 2025-01-01
    “…These compounds reduce neuronal apoptosis by modulating the expression of mitochondrial-associated apoptotic proteins. …”
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  12. 7512

    Endoscopic retrograde cholangiopancreatography training using a silicone simulator fabricated using a 3D printing technique (with videos) by Suk Pyo Shin, Kyong Joo Lee, Min Je Sung, Jong Chan Kim, Guk Bae Kim, Moo Yeop Kim, Sung Yong Han, Sung Ill Jang, Mamoru Takenaka, Chang-Il Kwon

    Published 2025-01-01
    “…An ERCP training model was generated using 3D printing techniques, including five distinct interchangeable and transparent ampullar–common bile duct (CBD) modules. A prospective study using this model was conducted with ten trainees. …”
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  13. 7513

    Weather Support for the 2008 Olympic and Paralympic Sailing Events by Yan Ma, Rongzhen Gao, Yunchuan Xue, Yuqiang Yang, Xiaoyun Wang, Bin Liu, Xiaoliang Xu, Xuezhong Liu, Jianwei Hou, Hang Lin

    Published 2013-01-01
    “…The refined forecasting system based on MM5, WRF, and statistical modules provided point-specific hourly wind forecasts for the five venues, and the severe weather monitoring and forecasting system was used in short-term forecasts and nowcasts for rainstorms, gales, and hailstones. …”
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  14. 7514

    Maintenance of Self-Renewal and Pluripotency in J1 Mouse Embryonic Stem Cells through Regulating Transcription Factor and MicroRNA Expression Induced by PD0325901 by Zhiying Ai, Jingjing Shao, Xinglong Shi, Mengying Yu, Yongyan Wu, Juan Du, Yong Zhang, Zekun Guo

    Published 2016-01-01
    “…Moreover, PD can significantly modulate the expressions of multiple miRNAs that have crucial functions in ESC development. …”
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  15. 7515

    Management Practices and Effectiveness of Universities at Lifelong Learning Realization by I. A. Korshunov, N. N. Shirkova, E. S. Szhenov, I. A. Efremov, G. A. Chakhoyan

    Published 2023-01-01
    “…Heads of lifelong learning programmes departments of 51 universities, realized the federal project, have been participating in the survey, as well as over 15.3 thousand students who provided a description of the qualitative characteristics of the educational services and programmes.The results of survey showed that the number of students participating in lifelong learning programmes at universities increase, as well as the profitability of the programmes potentially depends on management solutions: implementation of a strategy for the lifelong learning programmes development, the university’s participation in federal projects and programmes, implementation of new programmes offered (orientation on different target groups, training the corporate groups, the introduction of online modules and digitalization of programs, initiating the programmes for the development of supra-professional and digital skills), digitalization of lifelong learning programmes and use the network forms of cooperation, taking into account the specialists’ skills needed for employers, expanding relations with enterprises and business partners in the region.The authors of the article formulated proposals and recommendations for the lifelong learning programmes development in regional universities, taking into account the needs of employees, the needs of the real sector of the economy, the financial and economic effectiveness of educational services…”
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  16. 7516

    Nostoc commune Vauch. polysaccharide alleviates Pb-induced hepatorenal toxicity by changing gut bacteriome, mycobiome, and metabolome by Yue Liu, Ping Ren, Hailong Li, Yingying Liu, Yiting Yang, Wanting Wang, Jiaming Zhou, Ling Su, Lili Guan, Hongxia Ma

    Published 2024-11-01
    “…NCVP improved Pb-induced hepatorenal toxicity and inflammatory responses and modulated key indicators of antioxidant capacity. Moreover, the down-regulation of critical proteins of the Nrf2 pathway induced by Pb could be reversed after NCVP intervention. …”
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  17. 7517

    15-Lipoxygenase-1 Is Involved in the Effects of Atorvastatin on Endothelial Dysfunction by Peng Zhang, Xin Xing, Chunxiao Hu, Hui Yu, Qian Dong, Guanglei Chang, Shu Qin, Jian Liu, Dongying Zhang

    Published 2016-01-01
    “…Expression levels of CAMs and Akt/eNOS/NO under oxidized low-density lipoprotein (ox-LDL) stimulation were modulated by ALOX15 inhibitor and ALOX15 small interfering RNA (siRNA). …”
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  18. 7518

    Functionality multiplexing in high-efficiency metasurfaces based on coherent wave interferences by Yuejiao Zhou, Tong Liu, Changhong Dai, Dongyi Wang, Lei Zhou

    Published 2024-11-01
    “…Specifically, upon continuously modulating the incident polarization along different paths on the Poincare’s sphere, we show that the first device can generate two spatially non-overlapping vortex beams with strengths continuously tuned, while the second device can generate a vectorial vortex beam carrying continuously-tuned polarization distribution and/or orbital angular momentum. …”
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  19. 7519

    Explainable attention based breast tumor segmentation using a combination of UNet, ResNet, DenseNet, and EfficientNet models by Shokofeh Anari, Soroush Sadeghi, Ghazaal Sheikhi, Ramin Ranjbarzadeh, Malika Bendechache

    Published 2025-01-01
    “…To improve segmentation accuracy, the model integrates attention mechanisms, such as the Convolutional Block Attention Module (CBAM) and Non-Local Attention, with advanced encoder architectures, including ResNet, DenseNet, and EfficientNet. …”
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  20. 7520

    Functions of BCL-XL at the Interface between Cell Death and Metabolism by Judith Michels, Oliver Kepp, Laura Senovilla, Delphine Lissa, Maria Castedo, Guido Kroemer, Lorenzo Galluzzi

    Published 2013-01-01
    “…In particular, BCL-XL has been shown to modulate a number of pathophysiological processes, including—but not limited to—mitochondrial ATP synthesis, protein acetylation, autophagy and mitosis. …”
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