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7481
A Multi-Scale Convolutional Residual Time-Frequency Calibration Method for Low-Accuracy Air Pollution Data
Published 2025-01-01“…Residual connections merge the original and multi-scale features, preserving the initial input for enhanced stability. The calibration module employs Gated Recurrent Units (GRUs) to capture long-term dependencies in time-series data through reset and update gates. …”
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7482
Exploring TNFR1: from discovery to targeted therapy development
Published 2025-01-01“…This review emphasizes the emerging field of targeted therapies aimed at selectively modulating TNFR1 activity, identifying promising therapeutic strategies that exploit TNFR1 as a drug target through an evaluation of current clinical trials and preclinical studies. …”
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7483
A High-Precision Dynamic Six Degree-of-Freedom Pose Measurement of the Subreflectors of Large Antennas Based on a Position Sensitive Detector and Laser Array
Published 2022-01-01“…The laser emitted by the laser module array ensures that the PSD can be covered as it moves with the subreflector, and the PSD can obtain more than three laser beams. …”
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7484
Identification and validation of a prognostic risk model based on radiosensitivity-related genes in nasopharyngeal carcinoma
Published 2025-02-01“…Background: Despite advancements with intensity-modulated radiation therapy (IMRT), about 10 % of nasopharyngeal carcinoma (NPC) patients remain resistant to radiotherapy, leading to recurrence and poor prognosis. …”
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7485
Engineered CRISPR-Cas9 for Streptomyces sp. genome editing to improve specialized metabolite production
Published 2025-01-01“…Cas9-BD and similarly modified dCas9-BD have been successfully employed for simultaneous biosynthetic gene cluster (BGC) refactoring, multiple BGC deletions, or multiplexed gene expression modulations in Streptomyces. We also demonstrate improved secondary metabolite production using multiplexed genome editing with multiple single guide RNA libraries in several Streptomyces strains. …”
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7486
Reconfigurable Photonic Lattices Based on Atomic Coherence
Published 2025-01-01“…The inherited instantaneous tunability of susceptibility from EIT‐modulated atomic coherence allows for the easy reconfigurability of EIPLs, which gives rise to exotic beam dynamics under such a readily controllable framework. …”
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7487
Plasmonic Polarization Sensing of Electrostatic Superlattice Potentials
Published 2025-01-01“…We observe that the carrier density and the corresponding plasmonic response of graphene are modulated by polar domains in t-BN. In addition, we demonstrate that the nanometer-wide domain walls of graphene moirés superlattices, created by the polar domains of t-BN, provide momenta to assist the plasmonic excitations. …”
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7488
Instance-level semantic segmentation of nuclei based on multimodal structure encoding
Published 2025-02-01“…The framework incorporates: (1) A multi-scale feature fusion and knowledge distillation module utilizing the Contrastive Language-Image Pre-training (CLIP) model’s image encoder; (2) A method to transform morphological features of cells into textual descriptions for semantic representation; and (3) A graph neural network approach to learn spatial relationships and contextual information between cell nuclei. …”
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7489
Metabolic control of ovarian function through the sympathetic nervous system: role of leptin
Published 2025-02-01“…Metabolic signals, such as nutrients and hormones, acting on the hypothalamus may play a crucial role in modulating sympathetic innervation of the ovary and other reproductive organs. …”
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7490
High‐Speed Solar Wind Imprints on the Ionosphere During the Recovery Phase of the August 2018 Geomagnetic Storm
Published 2020-07-01“…It was found that the high‐speed solar wind was effective in modulating the intensity and the size of the auroral oval, high‐latitude convection, and potential pattern. …”
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7491
Role of bitter contributors and bitter taste receptors: a comprehensive review of their sources, functions and future development
Published 2024-07-01“…Furthermore, not only did the bitter taste receptors (taste receptor type 2 family, T2Rs) show taste effects, but extra-oral T2Rs could also be activated by binding with bitter components, regulating physiological activities via modulating hormone secretion, immunity, metabolism, and cell proliferation. …”
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7492
Light-YOLO: a lightweight detection algorithm based on multi-scale feature enhancement for infrared small ship target
Published 2025-01-01“…Additionally, a Multi-Scale Feature Enhancement Module (MFEB) is introduced to refine focus on low-level features through multi-scale and selection strategies, mitigating issues such as interference from image backgrounds and noise during small target detection. …”
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7493
Simulation of Photovoltaic Thermoelectric Battery Characteristics
Published 2021-06-01“…The 3D model of the proposed photovoltaic thermoelectric battery was realized in the COMSOL Multiphysics software environment with the use of a heat transfer module. The simulation was performed for the geographical coordinates of Minsk and taking into account the diurnal and seasonal variations of both the ambient temperature and the power density of the concentrated AM1.5 solar spectrum, the maximum value of which being varied from 1 to 500 kW/m2. …”
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7494
Defects of CTLA-4 Are Associated with Regulatory T Cells in Myasthenia Gravis Implicated by Intravenous Immunoglobulin Therapy
Published 2020-01-01“…Our mechanistic studies indicated that IVIg expands CTLA-4-Treg cells via modulating antigen-presenting dendritic cells (DCs). …”
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7495
A Model of Insulin Resistance in Mice, Born to Diabetic Pregnancy, Is Associated with Alterations of Transcription-Related Genes in Pancreas and Epididymal Adipose Tissue
Published 2011-01-01“…Adult IR and control offspring were selected and we determined the mRNA expression of transcription factors known to modulate pancreatic and adipose tissue activities and inflammation. …”
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7496
A Lightweight Anti-Unmanned Aerial Vehicle Detection Method Based on Improved YOLOv11
Published 2024-12-01“…Firstly, HWD is imported as the backbone’s downsampling module, which lowers feature loss in the feature extraction procedure while using fewer parameters. …”
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7497
LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis
Published 2015-01-01“…Recently, it was reported that the new ubiquitin ligase complex termed linear ubiquitin chain assembly complex (LUBAC), composed of SHARPIN (SHANK-associated RH domain-interacting protein), HOIL-1L (longer isoform of heme-oxidized iron-regulatory protein 2 ubiquitin ligase-1), and HOIP (HOIL-1L interacting protein), forms linear ubiquitin on NF-κB essential modulator (NEMO) and thereby induces NF-κB pathway activation. …”
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7498
Simulation and Test Study of Blast Crater in Deep Ore Body of Metal Mine Based on Lsdyna
Published 2024-01-01“…First, an exponential fitting function of the type “y=A×ex/B+C” is proposed to measure the rock body structure. Second, by modulating the strength and damage parameters and defining the unit failure criterion, the damage volume and blast action index obtained from the dynamic calculation are consistent with the 3D scanning results of the on-site blast crater test. …”
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7499
The influence of follicular fluid on the regulation of apoptosis and related genes during IVM of camel oocytes
Published 2025-01-01“…Acta2 and Tagln genes that relate to cytoskeletal protein “actin” in transforming growth factor beta (TGFβ) pathway were also modulated. However, the follicular fluid increased the expression of TGFβ in camel oocytes. …”
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7500
Automated text processing: topic segmentation of educational texts
Published 2019-09-01“…The most frequent theme is "Humanities", the reference to which is revealed in 9 modules. It is significant that textbook authors offer the following topics Gardening, Computers & Internet, Science & Mathematics, Entertainment& Recreation only once during the school year.…”
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