Mitochondrial diseases caused by toxic compound accumulation: from etiopathology to therapeutic approaches by Ivano Di Meo, Costanza Lamperti, Valeria Tiranti

“…Given the complexity of mitochondrial genetics and biochemistry, mitochondrial inherited diseases may present with a vast range of symptoms, organ involvement, severity, age of onset, and outcome. …”
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Alterations in mitochondrial base editors enhance targeted editing efficiency for mouse model generation by Seongho Hong, Sol Pin Kim, Sanghun Kim, Soo Kyung Kang, Sungmo Jung, Yeji Oh, Seung Hee Choi, Su Bin Lee, Hou Cha, Jieun Kim, Jiyoung Bae, Jiyoon Park, Kyoungmi Kim, Chang Geun Choi, Soo-Ji Park, Do Hyun Kim, Lark Kyun Kim, Je Kyung Seong, Hyunji Lee

“…These findings demonstrate the utility of the enhanced base editors in generating mitochondrial disease models and advancing research in mitochondrial genetics.…”
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The role of mitochondria-related genes in hepatocellular carcinoma prognosis: construction of prognostic models based on machine learning by Fei Gao, Fei Teng, Yuxiang Wan, Qiaoli Zhang, Jinchang Huang

“…Methods We systematically retrieved mitochondrial genetic data from the MitoCarta database and identified differentially expressed genes through Gene Expression Omnibus analysis. …”
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