Reducing catheter-associated urinary tract infections in a large health system: a quality improvement approach using a fractal management system by Elie A. Saade, Esther J. Thatcher, Tina Lewis, Susan Carr, Marcia Cornell, Rachel Arnold, Lisa Bushong, Zainab Albar, Peter Pronovost

“…Results: Enhanced communication and management played crucial roles in minimizing IUC placement. Updated policies and protocols, coupled with clear guidelines and decision support tools, facilitated effective urinary management. …”
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Optimization of a microarray for fission yeast by Dong-Uk Kim, Minho Lee, Sangjo Han, Miyoung Nam, Sol Lee, Jaewoong Lee, Jihye Woo, Dongsup Kim, Kwang-Lae Hoe

“…For PCR, the optimal annealing temperature (maximizing yield and minimizing extra bands) was 58℃ for both tags. Intriguingly, up-tags required 3× higher amounts of blocking oligonucleotides than down-tags. …”
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Spinal cord demyelination predicts neurological deterioration in patients with mild degenerative cervical myelopathy by Jefferson R Wilson, David Anderson, Stephan Duplessis, Julien Cohen-Adad, David W Cadotte, Nathan Evaniew, Jacques Bouchard, Michael Craig, Abdul Al-Shawwa, Kalum Ost, Steve Casha, W Bradley Jacobs, Saswati Tripathy, Peter Lewkonia, Fred Nicholls, Alex Soroceanu, Ganesh Swamy, Kenneth C Thomas, Michael MH Yang, Nicholas Dea

“…Clinical guidelines regarding surgery for patients with mild DCM and minimal symptoms remain uncertain. This study aims to identify imaging and clinical predictors of neurological deterioration in mild DCM and explore pathophysiological correlates to guide clinical decision-making.Methods Patients with mild DCM underwent advanced MRI scans that included T2-weighted, diffusion tensor imaging and magnetisation transfer (MT) sequences, along with clinical outcome measures at baseline and 6-month intervals after enrolment. …”
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Enhancing physicochemical, bioactive, and nutritional properties of sweet potatoes: Ultrasonic contact drying with slot jet nozzles compared to hot-air drying and freeze drying by Gulcin Yildiz, Yuan Gao, Junzhou Ding, Si Zhu, Guibing Chen, Hao Feng

“…SJR + US at 50 °C resulted in the lowest total color changes (ΔE), indicating minimal impact on appearance. Additionally, FTIR analysis revealed that peaks in specific spectral regions indicated superior preservation of bioactive compounds in SJR + US samples compared to other methods, which was also confirmed by principal component analysis (PCA) and heatmap visualization. …”
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Integrating biodiversity assessments into local conservation planning: the importance of assessing suitable data sources by Ferraille, Thibaut, Kerbiriou, Christian, Bigard, Charlotte, Claireau, Fabien, Thompson, John D.

“…Strategic Environmental Assessment (SEA) of land-use planning is a fundamental tool to minimize environmental impacts of artificialization. …”
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Accounting for microorganisms yields stricter water quality criteria and elevated ecological risks of antibiotics: A case study of sulfonamides in the Yangtze River Delta by Xinyang Zhang, Xiao Yun, Ye Huang, Guofeng Shen, Nan Lin

“…Three WQC types were calculated: based on native species (WQC-n), a combination of native and non-native species (WQC-nn), and a combination of species and microorganisms (WQC-nnm). While WQC-nn showed minimal differences from WQC-n, the inclusion of microbial data resulted in more conservative short-term WQCs (SWQC-nnm), calculated as 256.90 μg/L for SMX and 196.09 μg/L for SM2, approximately half of SWQC-nn values (435.20 μg/L for SMX and 491.11 μg/L for SM2). …”
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Oridonin: A natural terpenoid having the potential to modulate apoptosis and survival signaling in cancer by Abhishek Chauhan, Hemant Joshi, Divya Kandari, Diwakar Aggarwal, Ritu Chauhan, Hardeep Singh Tuli, Arpit Mehrotra, Abhilasha Sood, Ujjawal Sharma, Darin Mansor Mathkor, Shafiul Haque, Naveen Chandra Joshi, Laurent Dufossé

“…Its derivatives, such as 13p, exhibit enhanced potency by arresting the G2/M phase and targeting drug-resistant cells with minimal toxicity. Advanced nano-delivery systems and combination therapies further enhance oridonin's therapeutic potential. …”
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Phase 1 study of safety, tolerability, and efficacy of intradermal DNA vaccine ASP2390 in adults allergic to house dust mites by Thomas Kayser, MD, BS, Ronald Smulders, MD, PhD, Tomohiro Kusawake, PhD, Erik Wambre, PhD, Gurunadh R. Chichili, PhD, Mary B. Blauwet, DrPH, Anna Spence, MS, Melanie Patton, BS, Rima Tabash, PhD, Hannah A. DeBerg, PhD, Sugandhika Khosa, MS, Philipp Badorrek, MD, Jens M. Hohlfeld, MD, Brian C. Ferslew, PharmD, PhD

“…The novel LAMP (lysosomal-associated membrane protein)-based DNA vaccine ASP2390 targets major HDM allergens, potentially shifting immune responses toward nonallergic pathways and minimizing the risk of atopy, with positive safety and efficacy signals in preclinical models. …”
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Effects of hypoxia on the heart of the juvenile four-finger threadfin (Eleutheronema tetradactylum) based on physiological indicators and transcriptome analysis by Yi Lu, Eric Amenyogbe, Ye- Yang, Zhong-liang Wang, Zhong-liang Wang, Zhong-liang Wang, Jing-hui Jin, Rui-tao Xie, Eric Kwabena Droepenu, Jian-sheng Huang, Jian-sheng Huang, Jian-sheng Huang

“…This underscores the need to minimize oxygen fluctuations to prevent cardiac tissue degeneration. …”
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Advancing Pediatric Surgery: The Use of HoloLens 2 for 3D Anatomical Reconstructions in Preoperative Planning by Marco Di Mitri, Annalisa Di Carmine, Simone D’Antonio, Benedetta Maria Capobianco, Cristian Bisanti, Edoardo Collautti, Sara Maria Cravano, Francesca Ruspi, Michele Libri, Tommaso Gargano, Mario Lima

“…Background: In pediatric surgery, a comprehensive knowledge of the child’s anatomy is crucial to optimize surgical outcomes and minimize complications. Recent advancements in medical imaging and technology have introduced innovative tools that enhance surgical planning and decision-making. …”
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Inheritance of resistance to maize lethal necrosis in tropical maize inbred lines by Hilda M. Kavai, Hilda M. Kavai, Dan Makumbi, Felister M. Nzuve, Vincent W. Woyengo, L. M. Suresh, William M. Muiru, Manje Gowda, Boddupalli M. Prasanna

“…Reciprocal effects were not significant for MLN resistance, suggesting minimal maternal or cytoplasmic inheritance. Four inbred lines showed significant negative GCA effects for MLN resistance and positive GCA effects for GY under artificial MLN inoculation. …”
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Caudal vena cava isolation using ablation index‐guided radiofrequency catheter ablation (CARTO™ 3) to treat sustained atrial tachycardia in horses by Eva Buschmann, Glenn Van Steenkiste, Ingrid Vernemmen, Marie Demeyere, Stijn Schauvliege, Annelies Decloedt, Gunther vanLoon

“…Ablation index guidance ensured efficient lesion creation, and isolation of the caudal vena cava eliminated the arrhythmogenic substrate, thereby minimizing the risk of recurrence.…”
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Combination of ataxia telangiectasia and Rad3-related inhibition with ablative radiotherapy remodels the tumor microenvironment and enhances immunotherapy response in lung cancer by Jenny Ling-Yu Chen, Chun-Kai Pan, Li-Cheng Lin, Yu-Sen Huang, Tsung-Hsuan Huang, Shu-Jyuan Yang, Sung-Hsin Kuo, Yu-Li Lin

“…Safety analysis showed minimal toxicity. ATR inhibition enhanced the efficacy of ablative radiotherapy and immunotherapy in lung cancer. …”
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Lightweight YOLOv8s-Based Strawberry Plug Seedling Grading Detection and Localization via Channel Pruning by CHEN Junlin, ZHAO Peng, CAO Xianlin, NING Jifeng, YANG Shuqin

“…The proposed two-stage seedling-hole matching algorithm effectively minimized the interference caused by overgrown seedlings, accurately locating and classifying seedlings of various growth stages within the plug tray. …”
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Surgical interventions for spontaneous supratentorial intracerebral haemorrhage: a systematic review and network meta-analysisResearch in context by Jiayidaer Huan, Minghong Yao, Yu Ma, Fan Mei, Yanmei Liu, Lu Ma, Xiaochao Luo, Jiali Liu, Jianguo Xu, Chao You, Hunong Xiang, Kang Zou, Xiao Liang, Xin Hu, Ling Li, Xin Sun

“…Summary: Background: Surgical interventions for spontaneous supratentorial intracerebral haemorrhage (ICH) include conventional craniotomy (CC), decompressive craniectomy (DC), and minimally invasive surgery (MIS), with the latter encompassing endoscopic surgery (ES) and minimally invasive puncture surgery (MIPS). …”
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Stem cells prevent long-term deterioration of renal function after renal artery revascularization in a renovascular hypertension model in rats by Nikolas Waack, Tatiana Guirao, Edgar Maquigussa, Erika Nishi, Milene Ormanji, Olinda Ykuta, Mirian Boim

“…Mesenchymal stem cells (MSCs) have produced discrete results in minimizing RVH and renal tissue and functional improvements since the obstruction persists. …”
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Percutaneous nephroscopy versus flexible ureteroscopy in the treatment of calyceal diverticulum calculi: a meta-analysis by Conglei Hu, Rui Ma, Yongxiang Shao, Zilong Liang, Meng Cheng, Haofeng Pang, Liping Yao, Fei Liu

“…Abstract Background There is still controversy about the best minimally invasive surgical method for the treatment of calyceal diverticulum calculi. …”
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Temporary spinal cord stimulation combined with lidocaine patch for postherpetic neuralgia in the elderly: a controlled study by Yun Li, Chunhui Hao, Shengtao Wang, Feng Qiu, Xuli Zhao, Tao Sun

“…Patients with PHN duration <60 days benefited more from combination therapy. Adverse events were minimal and similar between groups.ConclusionCombining SCS with lidocaine patches significantly enhances pain relief and sleep quality in elderly PHN patients compared to SCS alone. …”
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Adverse birth outcome and associated factors among mothers with antepartum hemorrhage in public hospitals Tigray, northern Ethiopia, 2020 by Tomas Amare Abraha, Gebremedhin Kinfe Gebremariam, Berhane Teklay Asfaha, Tensay Kahsay Weldegebreal, Desta Hailu Aregawi

“…Predictors could be minimized by strengthening antenatal care follow up, ensuring early arrival to health institution, and focusing on rural area.…”
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Catastrophic health expenditure associated with non-inpatient costs among middle-aged and older individuals in China by Xiaojuan Zhang, Kun Zhu

“…However, reimbursement for non-inpatient expenditures is significantly limited under the two predominant health insurance schemes, and there is minimal disparity in the distribution of non-inpatient expenses before and after insurance reimbursement. …”
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